Human lung surfactant protein A exists in several different oligomeric states: Oligomer size distribution varies between patient groups

Molecular Medicine

Volumn 4, Issue 4, 1998, Pages 266-275

  Hickling, Timothy P ^a   Malhotra, Rajneesh ^b   Sim, Robert B ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALLERGEN; LECTIN; LUNG SURFACTANT; OLIGOMER;

ALLERGY; ARTICLE; BINDING AFFINITY; DEPOLYMERIZATION; ENZYME LINKED IMMUNOSORBENT ASSAY; GEL FILTRATION; HOST RESISTANCE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOBLOTTING; LUNG LAVAGE; OLIGOMERIZATION; POLLEN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEINOSIS; SUCROSE DENSITY GRADIENT CENTRIFUGATION;

EID: 0031852357     PISSN: 10761551     EISSN: None     Source Type: Journal    
DOI: 10.1007/bf03401923     Document Type: Article

References (35)

1. Malhotra R, Lu J, Holmskov U, Sim RB. (1994) Collectins, collectin receptors and the lectin pathway of complement activation. Clin. Exp. Immunol. 2: 4-9.
2. Holmskov U, Malhotra R, Sim RB, Jensenius J-C. (1994) Collectins: Collagenous C-type lectins of the innate immune defence system. Immunol. Today 15: 67-74.
3. Sastry K, Ezekowitz RA. (1993) Collectins: Pattern recognition molecules involved in first line host defence. Curr. Opin. Immunol. 5: 59-66.
4. Suzuki Y, Fugita Y, Kogishi K. (1989) Reconstitution of tubular myelin from synthetic lipids and proteins associated with pig pulmonary surfactant. Am. Rev. Respir. Dis. 140: 75-81.
5. Williams MC, Hawgood S, Hamilton RL. (1991) Changes in lipid structure produced by surfactant proteins SP-A, SP-B, and SP-C. Am. J. Respir. Cell Mol. Biol. 5: 41-50.
6. Dobbs LG, Wright JR, Hawgood S, Gonzales R, Venstrom K, Nellenbogen J. (1987) Pulmonary surfactant and its components inhibit the secretion of phosphatidylcholine from cultured alveolar type II cell. Proc. Nat. Acad. Sci. U.S.A. 84: 1010-1014.
7. Chung J, Yu SH, Whitsett JA, Harding PG, Possmayer F. (1989) Effect of surfactant-associated protein-A (SP-A) on the activity of lipid extract surfactant. Biochim. Biophys. Acta 1002: 348-358.
8. Schurch S, Possmayer F, Cheng S, Cockshutt AM. (1992) Pulmonary SP-A enhances adsorption and appears to induce surface sorting of lipid extract surfactant. Am. J. Physiol. 263 (Lung Cell. Mol. Physiol. 11): L210-218.
9. Reid KBM. (1993) Structure/function relationships in the Collectins (mammalian lectins containing collagen-like regions). Biochem. Soc. Trans. 21: 464-468.
10. Voss T, Eistetter H, Schafer KP, Engel J. (1988) Macromolecular organisation of natural and recombinant lung surfactant protein SP 28-36. Structural homology with the complement factor Clq. J. Mol. Biol. 201: 219-227.
11. Lu J, Wiedemann H, Timpl R, Reid KBM. (1993) Similarity in structure between Clq and the collectins as judged by electron microscopy. Behring Inst. Mitt. 93: 6-16.
12. Hawgood S. (1989) Pulmonary surfactant apoproteins: A review of protein and genoinic structure. Am. J. Physiol. 257 (Lung Cell. Mol. Physiol. 2): L13-L22.
13. Lu J, Sim RB. (1994) Collectins and Collectin Receptors. In: Erdei A (ed). New Aspects of Complement Structure and Function. R.G. Landes, Austin, TX, pp. 85-106.
14. Thiel S, Reid KBM. (1989) Structures and functions associated with the group of mammalian lectins containing collagen-like sequences. FEBS Lett. 250: 78-84.
15. 5. Geertsma MF, Nibbering PH, Haagsman HP, Daha MR, Van-Furth R. (1994) Binding of surfactant protein A to Clq receptors mediates phagocytosis of Staphylococcus aureus by monocytes. Am. J. Physiol. 267 (Lung Cell. Mol. Physiol. 11): L578-584.
16. Malhotra R, Haurum J, Thiel S, Sim, RB. (1994) Binding of human Collectins (SP-A and MBP) to influenza virus. Biochetn. J. 304: 455-461.
17. Malhotra R, Haurum J, Thiel S, Jensenius J-C, Sim RB. (1993) Pollen grains bind to lung alveolar lype II cells (A549) via lung surfactant protein A (SP-A). Biosci. Rep. 13: 79-90.
18. Downing JF, Pasula R, Wright JR, Twigg HL, Martin WJ. (1995) Surfactant protein A promotes attachment of Mycobacterium tuberculosis to alveolar macrophage during infection with human immunodeficiency virus. Prof. Nat. Acad. Sci. U.S.A. 92: 4848-4852.
19. Kabha K, Schmegner J, Keisari Y, Parolis H, Schlepper-Schaefer J, Ofek I. (1997) SP-A enhances phagocytosis of Klebsiella by interaction with capsular polysaccharides and alveolar macrophage. Am. J. Physiol 272 (Lung Cell. Mol. Physiol. 16): L344-L352.
20. LeVine AM, Bruno MD, Huelsman KM, Ross GF, Whitsett JA, Korfhagen TR. (1997) Surfactant protein A-deficient mice are susceptible to group B streptococcal infection. J. Immunol. 158: 4336-4340.
21. Ikegami M, Korfhagen TR, Bruno MD, Whitsett JA, Jobe AH. (1997) Surfactant metabolism in surfactant protein A-deficient mice. Am. J. Physiol. 272 (Lung Cell. Mol. Physiol. 16): L479-L485.
22. Weis WI, Drickamer K. (1996) Structural basis of lectin-carbohydrate recognition. Ann. Rev. Biochem. 65: 441-473.
23. Holmskov U, Laursen SB, Malhotra R, et al. (1995) Comparative study of the structural and functional properties of a bovine plasma C-type lectin, collectin-43, with other collectins. Biochem. J. 305: 889-896.
24. Stuart GR, Sim RB, Malhotra R. (1996) Characterisation of radioiodinated lung surfactant protein A (SP-A) and the effects of oxidation on SP-A quaternary structure and activity. Exp. Lung. Res. 22: 467-487.
25. 2 complex, of the classical pathway of complement, without involvement of Clq. J. Immunol. 144: 2287-2294.
26. Lipscombe RJ, Sumiya M, Summerfield JA, Turner MW. (1995) Distinct physicochemical characteristics of human mannose binding protein expressed by individuals of differing genotype. Immunology 85: 660-667.
27. Weaver TE, Whitsett JA. (1991) Function and regulation of expression of pulmonary surfactant-associated proteins. Biochem. J. 273: 249-264.
28. Laemmli UK. (1970). Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227: 680-685.
29. Fairbanks G, Steck TL, Wallach DFH. (1971) Electrophoretic analysis of the major polypeptides of the human erythrocyte membrane. Biochemistry 10: 2606-2610.
30. Towbin H, Staehelin T, Gordon J. (1979) Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications. Proc. Nat. Acad. Sci. U.S.A. 76: 4350-4355.
31. Ackers GK. (1964) Molecular exclusion and restricted diffusion processes in molecular-sieve chromatography. Biochemistry 3: 723-730.
32. Smith MH. (1970) Peptides and Proteins. In: Sober HA (ed). Handbook of Biochemistry and Selected Data for Molecular Biology. CRC Press, Cleveland, pp. C3-28.
33. Martin RG, Ames BN. (1961) A method of determining the sedimentation behaviour of enzymes: Application to protein mixtures. J. Biol. Chem. 236: 1372-1379.
34. Siegel LM, Monty KJ. (1966) Determination of molecular weights and frictional ratios of proteins in impure system by use of gel filtration and density gradient centrifugation. Biochim. Biophys. Acta 112: 346-359.
35. Passero MA, Tye RW, Kilburn KH, Lynn WS. (1973) Isolation and characterisation of two glycoproteins from patients with alveolar proteinosis. Proc. Nat. Acad. Sci. U.S.A. 70: 973-976.