Methodology based on chiral silanes in the synthesis of polypropionate-derived natural products - Total synthesis of epothilone A

European Journal of Organic Chemistry

Volumn , Issue 9, 2001, Pages 1701-1714

  Zhu, Bin ^a   Panek, James S ^b  

^a R W JOHNSON PHARMACEUTICAL RES I   (United States)

^b Boston University   (United States)

Author keywords

Antitumor natural products; Asymmetric synthesis; Chiral silane reagent; Epothilone; Lipase resolution

Indexed keywords

EPOTHILONE A; EPOTHILONE B; NATURAL PRODUCT; PROPIONIC ACID; SILANE DERIVATIVE; TAXOL; TRIACYLGLYCEROL LIPASE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL REACTION; DRUG MECHANISM; DRUG SYNTHESIS; PROTON NUCLEAR MAGNETIC RESONANCE;

EID: 0035034609     PISSN: 1434193X     EISSN: None     Source Type: Journal    
DOI: 10.1002/1099-0690(200105)2001:9<1701::AID-EJOC1701>3.0.CO;2-%23     Document Type: Article

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