A role for complement C5 in organism containment and granulomatous response during murine tuberculosis

Scandinavian Journal of Immunology

Volumn 53, Issue 5, 2001, Pages 464-474

  Actor, J K ^a,c   Breij, E ^a   Wetsel, R A ^b   Hoffmann, H ^a   Hunter Jr , R L ^a   Jagannath, C ^a  

^a UNIVERSITY OF TEXAS   (United States)

^b UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^c BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE; COMPLEMENT COMPONENT C5; CYTOKINE; INTERLEUKIN 12; MACROPHAGE INFLAMMATORY PROTEIN 2; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL INFECTION; COMPLEMENT DEFICIENCY; CONGENIC STRAIN; CYTOKINE PRODUCTION; GRANULOMATOUS INFLAMMATION; MACROPHAGE; MOUSE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; TUBERCULOSIS;

ANIMALS; CHEMOKINES; COMPLEMENT C5; CYTOKINES; DOWN-REGULATION; GRANULOMA, RESPIRATORY TRACT; INTERLEUKIN-12; LUNG; MACROPHAGES; MICE; MICE, CONGENIC; MICE, KNOCKOUT; MYCOBACTERIUM TUBERCULOSIS; RNA, MESSENGER; TUBERCULOSIS, PULMONARY;

EID: 0035032920     PISSN: 03009475     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-3083.2001.00902.x     Document Type: Article

References (41)

1. Evidence inconsistent with a role for the Bcg gene (Nrampl) in resistance of mice to infection with virulent Mycobacterium tuberculosis
2. Resistance ranking of some common inbred mouse strains to Mycobacterium tuberculosis and relationship to major histocompatiblity complex haplotype and Nrampl genotype
3. Relationship between Survival, Organism Containment and Granuloma Formation in Acute Murine Tuberculosis
4. Apoptosis in Murine Mycobacterium tuberculosis Infection in Mice Exhibiting Varied Immunopathology
5. Haplotype mapping and sequence analysis of the mouse Nramp gene predict susceptibility to infection with intracellular parasites
6. Genetic control of resistance to Listeria monocytogenes: Regulation of leukocyte inflammatory responses by the Hc locus
7. Adequate expression of protective immunity in the absence of granuloma formation in Mycobacterium tuberculosis-infected mice with a disruption in the intracellular adhesion molecule 1 gene
8. Cytokine/chemokine cascades in immunity to tuberculosis
9. Comparison of subcutaneous and intraperitoneal staphylococcal infections in normal and complement-deficient mice
10. The pulmonary response of C5 sufficient and deficient mice to Pseudomonas aeruginosa
11. Complement component C5 modulates the systemic tumor necrosis factor response in murine endotoxic shock
12. Hypersusceptibility of A/J mice to tuberculosis is in part due to a deficiency of the fifth complement component (C5)
13. A gene locus concerned with hemolytic complement in Mus musculus
14. Deficiency of the fifth component of complement in mice with an inherited complement defect
15. Structure of the murine fifth complement component (C5) gene. A large, highly interrupted gene with a variant donor splice site and organizational homology with the third and fourth complement component genes
16. Activities of poloxamer CRL8131 against Mycobacterium tuberculosis in vitro and in vivo
17. Analysis of cytokine mRNA expression during primary granuloma formation induced by eggs of Schistosoma mansoni
18. Evaluation of electrochemiluminescence- and bioluminescence-based assays for quantitating specific DNA
19. A flash-type bioluminescent immunoassay that is more sensitive than radioimaging: Quantitative detection of cytokine cDNA in activated and resting human cells
20. A flexible bioluminescent-quantitative polymerase chain reaction assay for analysis of competitive PCR amplicons
21. Cytokine gene expression after in vivo primary immunization with goat antibody to mouse IgD antibody
22. Selective suppression of interleukin-12 induction after macrophage receptor ligation
23. Deficiency of the murine fifth complement component (C5). A 2-base pair gene deletion in a 5′-exon
24. Genetics of MuB1 and of a complement defect in inbred strains of mice
25. NF-kappaB activation is required for C5a-induced interleukin-8 gene expression in mononuclear cells
26. In vitro and in vivo dependency of chemokine generation on C5a and TNF-alpha
27. C3a and C5a enhance granulocyte adhesion to endothelial and epithelial cell monolayers: Epithelial and endothelial priming is required for C3a-induced eosinophil adhesion
28. Migration of dendritic cells in response to formyl peptides, C5a, and a distinct set of chemokines
29. Dendritic cell migration in different micropore filter assays
30. Role of complement, chemokines, and regulatory cytokines in acute lung injury
31. Synergistic enhancement of chemokine generation and lung injury by C5a or the membrane attack complex of complement
32. The cytolytically inactive terminal complement complex activates endothelial cells to express adhesion molecules and tissue factor procoagulant activity
33. Enhancement by the complement membrane attack complex of tumor necrosis factor-alpha-induced endothelial cell expression of Eselectin and ICAM-1
34. Granuloma formation is required to contain bacillus growth and delay mortality in mice chronically infected with Mycobacterium tuberculosis
35. The cysteinecysteine family of chemokines RANTES, MIP-1alpha, and MIP-Ibeta induce trypanocidal activity in human macrophages via nitric oxide
36. Pathogenesis of pulmonary tuberculosis: An interplay of tissue damaging and macrophage activating immune responses-dual mechanisms that control bacillary multiplication
37. CRL-1072 enhances antimycobacterial activity of human macrophages through interleukin-8
38. Comparative effect of C3a and C5a on adhesion molecule expression on neutrophils and endothelial cells