-
1
-
-
0033572417
-
Hypoxia induces p53 accumulation through MDM2 down-regulation and inhibition of E6-mediated degradation
-
Alarcon R, Koumenis C, Geyer RK, Maki CG, Giaccia AJ (1999) Hypoxia induces p53 accumulation through MDM2 down-regulation and inhibition of E6-mediated degradation. Cancer Res 59: 6046-6051
-
(1999)
Cancer Res
, vol.59
, pp. 6046-6051
-
-
Alarcon, R.1
Koumenis, C.2
Geyer, R.K.3
Maki, C.G.4
Giaccia, A.J.5
-
2
-
-
0028929988
-
Replacement of the p16/CDKN2 gene suppresses human glioma cell growth
-
Arap W, Nishikawa R, Furnari FB, Cavenee WK, Huang H-JS (1995) Replacement of the p16/CDKN2 gene suppresses human glioma cell growth. Cancer Res 55: 1351-1354
-
(1995)
Cancer Res
, vol.55
, pp. 1351-1354
-
-
Arap, W.1
Nishikawa, R.2
Furnari, F.B.3
Cavenee, W.K.4
Huang, H.-J.5
-
3
-
-
0030613650
-
Functional analysis of wild-type and malignant glioma derived CDKN2AAralleles: Evidence for an rb-independent growth suppressive pathway
-
Arap W, Knudsen E, Sewell DA, Sidransky D, Wang JY, Huang HS, Cavenee WK (1997) Functional analysis of wild-type and malignant glioma derived CDKN2AAralleles: evidence for an RB-independent growth suppressive pathway. Oncogene 15: 2013-2020
-
(1997)
Oncogene
, vol.15
, pp. 2013-2020
-
-
Arap, W.1
Knudsen, E.2
Sewell, D.A.3
Sidransky, D.4
Wang, J.Y.5
Huang, H.S.6
Cavenee, W.K.7
-
4
-
-
0033090071
-
Combined radiation and p53 gene therapy and malignant glioma cells
-
Badie B, Goh CS, Klaver J (1999) Combined radiation and p53 gene therapy and malignant glioma cells. Cancer Gene Therapy 6: 155
-
(1999)
Cancer Gene Therapy
, vol.6
, pp. 155
-
-
Badie, B.1
Goh, C.S.2
Klaver, J.3
-
6
-
-
0028838446
-
Dominant oncogenes, tumor suppressors, and radiosensitivity
-
Chiarugi V, Magnelli L, Cinelli M (1995) Dominant oncogenes, tumor suppressors, and radiosensitivity. Cell Mol Biol Res 41: 161
-
(1995)
Cell Mol Biol Res
, vol.41
, pp. 161
-
-
Chiarugi, V.1
Magnelli, L.2
Cinelli, M.3
-
8
-
-
0028171454
-
p53 gene mutations are associated with decreased sensitivety of human lymphoma cells to DNA damaging agents
-
Fan S, El-Deiry WS, Bac I, Freeman J, Jondle D, Bhatia K, Fornace AJ, Magrath I, Kohn KW, O'Connor P (1994) p53 gene mutations are associated with decreased sensitivety of human lymphoma cells to DNA damaging agents. Cancer Res 54: 5824-5830
-
(1994)
Cancer Res
, vol.54
, pp. 5824-5830
-
-
Fan, S.1
El-Deiry, W.S.2
Bac, I.3
Freeman, J.4
Jondle, D.5
Bhatia, K.6
Fornace, A.J.7
Magrath, I.8
Kohn, K.W.9
O'Connor, P.10
-
9
-
-
0031743815
-
Restoration of the p16 gene is related to increased radiosensitivity of p16-deficient lung adenocarcinoma cell lines
-
Fu XY, Zhang SW, Ran RQ, Shen ZH, Gu JX, Cao SL (1998) Restoration of the p16 gene is related to increased radiosensitivity of p16-deficient lung adenocarcinoma cell lines. J Cancer Res Clin Oncol 124: 621-626
-
(1998)
J Cancer Res Clin Oncol
, vol.124
, pp. 621-626
-
-
Fu, X.Y.1
Zhang, S.W.2
Ran, R.Q.3
Shen, Zh.4
Gu, J.X.5
Cao, S.L.6
-
11
-
-
0030778842
-
ARF
-
ARF. Cell 91: 555-558
-
(1997)
Cell
, vol.91
, pp. 555-558
-
-
Haber, D.A.1
-
12
-
-
9344266882
-
The p53 gene is a potent determinant of chemosensitivity and radiosensitivity in gastric and colorectal cancers
-
Hamada M, Fujiwara T, Hizuta A, Gochi A, Naonoto Y, Takakura N, Takahashi K, Roth JA, Tanaka N, Orita K (1996) The p53 gene is a potent determinant of chemosensitivity and radiosensitivity in gastric and colorectal cancers. J Cancer Res Clin Oncol 122: 360-365
-
(1996)
J Cancer Res Clin Oncol
, vol.122
, pp. 360-365
-
-
Hamada, M.1
Fujiwara, T.2
Hizuta, A.3
Gochi, A.4
Naonoto, Y.5
Takakura, N.6
Takahashi, K.7
Roth, J.A.8
Tanaka, N.9
Orita, K.10
-
13
-
-
0029909822
-
INK4a-N in mouse-lung tumor cells
-
INK4a-N in mouse-lung tumor cells. Oncogene 13: 1885-1891
-
(1996)
Oncogene
, vol.13
, pp. 1885-1891
-
-
Herzog, C.R.1
Soloff, E.V.2
McDoniels, A.L.3
Tyson, F.L.4
Malkinson, A.M.5
Strano, A.H.6
Wiseman, R.W.7
Anderson, M.W.8
You, M.9
-
14
-
-
0028121279
-
A cell cycle regulator potentially involved in genesis of many tumor types
-
Kamb A, Gruis NA, Weaver-Feldhaus J, Liu Q, Harshman K, Tavtigian SV, Stockert E, Day RS, Johnson BE, Skolnick MH (1994) A cell cycle regulator potentially involved in genesis of many tumor types. Science 264: 436-440
-
(1994)
Science
, vol.264
, pp. 436-440
-
-
Kamb, A.1
Gruis, N.A.2
Weaver-Feldhaus, J.3
Liu, Q.4
Harshman, K.5
Tavtigian, S.V.6
Stockert, E.7
Day, R.S.8
Johnson, B.E.9
Skolnick, M.H.10
-
15
-
-
0030728468
-
ARF
-
ARF. Cell 91: 649-659
-
(1997)
Cell
, vol.91
, pp. 649-659
-
-
Kamijo, T.1
Zindy, F.2
Roussel, M.F.3
Quelle, D.E.4
Downing, J.R.5
Ashmun, R.A.6
Grosveld, G.7
Sherr, C.J.8
-
16
-
-
0032493350
-
Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2
-
Kamijo T, Weber JD, Zambetti G, Zindy F, Roussel MF, Sherr CJ (1998) Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2. Proc Natl Acad Sci USA 95: 8292-8297
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 8292-8297
-
-
Kamijo, T.1
Weber, J.D.2
Zambetti, G.3
Zindy, F.4
Roussel, M.F.5
Sherr, C.J.6
-
17
-
-
0023186270
-
The raf oncogene is associated with a radiation-resistant human laryngeal cancer
-
Kasid U, Pfeifer A, Weichselbaum RR, Kritschilo A, Mark G (1987) The raf oncogene is associated with a radiation-resistant human laryngeal cancer. Science 237: 1039-1041
-
(1987)
Science
, vol.237
, pp. 1039-1041
-
-
Kasid, U.1
Pfeifer, A.2
Weichselbaum, R.R.3
Kritschilo, A.4
Mark, G.5
-
18
-
-
9844219749
-
High frequency of simultaneous loss of p16 and p16Kagene expression in squamous cell carcinoma of the esophagus but not in adenocarcinoma of the esophagus or stomach
-
Kazuhiko H, Metzger R, Saloniga D, Danenberg K, Leichamab LP, Fink U, Sendler A, Kelsen D, Schwartz GK, Groshen S, Lenz HJ, Danenberg PV (1997) High frequency of simultaneous loss of p16 and p16Kagene expression in squamous cell carcinoma of the esophagus but not in adenocarcinoma of the esophagus or stomach. Oncogene 15: 1481-1488
-
(1997)
Oncogene
, vol.15
, pp. 1481-1488
-
-
Kazuhiko, H.1
Metzger, R.2
Saloniga, D.3
Danenberg, K.4
Leichamab, L.P.5
Fink, U.6
Sendler, A.7
Kelsen, D.8
Schwartz, G.K.9
Groshen, S.10
Lenz, H.J.11
Danenberg, P.V.12
-
19
-
-
0029052951
-
Tumor-derived p16 alleles encoding proteins defective in cell cycle inhibition
-
Koh J, Enders GH, Dynlacht BD, Harlow E (1995) Tumor-derived p16 alleles encoding proteins defective in cell cycle inhibition. Nature 375: 506-510
-
(1995)
Nature
, vol.375
, pp. 506-510
-
-
Koh, J.1
Enders, G.H.2
Dynlacht, B.D.3
Harlow, E.4
-
20
-
-
9544251503
-
p16 and p16p1 are potent growth suppressors of head and neck squamous carcinoma cells in vitro
-
Liggett WH, Sewell DA, Rocco J, Ahrendt SA, Doch W, Sidransky D (1996) p16 and p16p1 are potent growth suppressors of head and neck squamous carcinoma cells in vitro. Cancer Res 56: 4119-4123
-
(1996)
Cancer Res
, vol.56
, pp. 4119-4123
-
-
Liggett, W.H.1
Sewell, D.A.2
Rocco, J.3
Ahrendt, S.A.4
Doch, W.5
Sidransky, D.6
-
22
-
-
0027931008
-
Cell cycle arrests and radiosensitivity of human tumor cell lines: Dependence on wild-type p53 for radiosensitivity
-
McIlwrath AJ, Wasey PA, Ross GM, Brown R (1994) Cell cycle arrests and radiosensitivity of human tumor cell lines: dependence on wild-type p53 for radiosensitivity. Cancer Res 54: 3718-3722
-
(1994)
Cancer Res
, vol.54
, pp. 3718-3722
-
-
McIlwrath, A.J.1
Wasey, P.A.2
Ross, G.M.3
Brown, R.4
-
23
-
-
0026129706
-
Increased g2 delay in radiation-resistant cells obtained by transformation of primary rat embryo cells with the oncogenes H-ras and v-myc
-
McKenna WG, Iliakis G, Weiss MC, Bernhard EJ, Muschel RJ (1991) Increased G2 delay in radiation-resistant cells obtained by transformation of primary rat embryo cells with the oncogenes H-ras and v-myc. Radiat Res 125: 283-287
-
(1991)
Radiat Res
, vol.125
, pp. 283-287
-
-
McKenna, W.G.1
Iliakis, G.2
Weiss, M.C.3
Bernhard, E.J.4
Muschel, R.J.5
-
25
-
-
0031050047
-
Increased radiosensitivity of p16 gene-deleted human glioma cells after transfection with wild-type p16 gene
-
Miyakoshi J, Kitagawa K, Yamagishi N, Ohtsu S, Day RS, Takebe H (1997) Increased radiosensitivity of p16 gene-deleted human glioma cells after transfection with wild-type p16 gene. Jpn J Cancer Res 88: 34-38
-
(1997)
Jpn J Cancer Res
, vol.88
, pp. 34-38
-
-
Miyakoshi, J.1
Kitagawa, K.2
Yamagishi, N.3
Ohtsu, S.4
Day, R.S.5
Takebe, H.6
-
26
-
-
0028168452
-
Relationship between gamma-ray-induced G2/M delay and cellular radiosensitivity
-
Nagasawa H, Keng P, Harley R (1994) Relationship between gamma-ray-induced G2/M delay and cellular radiosensitivity. Int J Radiat Biol 66: 373
-
(1994)
Int J Radiat Biol
, vol.66
, pp. 373
-
-
Nagasawa, H.1
Keng, P.2
Harley, R.3
-
27
-
-
0027421045
-
Role of the p53 tumor suppressor gene in cell cycle arrest and radiosensitivity of Burkitt's lymphoma cell lines
-
O'Connor PM, Jackman J, Jondle D, Bhatia K, Magrath I, Kohn K (1993) Role of the p53 tumor suppressor gene in cell cycle arrest and radiosensitivity of Burkitt's lymphoma cell lines. Cancer Res 53: 4776-4780
-
(1993)
Cancer Res
, vol.53
, pp. 4776-4780
-
-
O'Connor, P.M.1
Jackman, J.2
Jondle, D.3
Bhatia, K.4
Magrath, I.5
Kohn, K.6
-
28
-
-
0028987265
-
INK4B/MTS2, and p18 genes in primary and metastatic lung cancer
-
INK4B/MTS2, and p18 genes in primary and metastatic lung cancer. Cancer Res 55: 1448-1451
-
(1995)
Cancer Res
, vol.55
, pp. 1448-1451
-
-
Okamota, A.1
Hussain, S.P.2
Hagiwara, K.3
Spillare, E.A.4
Rusin, M.R.5
Demetrick, D.J.6
Serrano, M.7
Hannon, G.J.8
Shiseki, M.9
Zariwala, M.10
Xiong, Y.11
Beach, D.H.12
Yokota, J.13
Harris, C.C.14
-
29
-
-
0032549704
-
Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53
-
Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53. Cell 92: 713-723
-
(1998)
Cell
, vol.92
, pp. 713-723
-
-
Pomerantz, J.1
Schreiber-Agus, N.2
Liegeois, N.J.3
Silverman, A.4
Alland, L.5
Chin, L.6
Potes, J.7
Chen, K.8
Orlow, I.9
Lee, H.W.10
Cordon-Cardo, C.11
DePinho, R.A.12
-
30
-
-
0029780350
-
The influence of the oncogenes NRAS and MYC on the radiation sensitivety of cells of a human melonoma cell line
-
Pomp J, Ouwerkerk IJM, Hermans J, Wondergem J, Cornelisse CJ, Leer JW, Schrier P (1996) The influence of the oncogenes NRAS and MYC on the radiation sensitivety of cells of a human melonoma cell line. Radiat Res 146: 374-381
-
(1996)
Radiat Res
, vol.146
, pp. 374-381
-
-
Pomp, J.1
Ouwerkerk, I.J.M.2
Hermans, J.3
Wondergem, J.4
Cornelisse, C.J.5
Leer, J.W.6
Schrier, P.7
-
31
-
-
0029587551
-
Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated protein capable of inducing cell cycle arrest
-
Quelle DE, Zindy F, Ashmun RA, Sherr CJ (1995) Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated protein capable of inducing cell cycle arrest. Cell 83: 993-1000
-
(1995)
Cell
, vol.83
, pp. 993-1000
-
-
Quelle, D.E.1
Zindy, F.2
Ashmun, R.A.3
Sherr, C.J.4
-
32
-
-
0033592584
-
Inactivation of the INK4A/ARF locus frequently coexists with TP53 mutations in non-small cell lung cancer
-
Sanchez-Cespedes M, Reed AL, Buta M, Wu L, Westra WH, Herman JG, Yang SC, Jen J, Sidransky D (1999) Inactivation of the INK4A/ARF locus frequently coexists with TP53 mutations in non-small cell lung cancer. Oncogene 18: 5843-5849
-
(1999)
Oncogene
, vol.18
, pp. 5843-5849
-
-
Sanchez-Cespedes, M.1
Reed, A.L.2
Buta, M.3
Wu, L.4
Westra, W.H.5
Herman, J.G.6
Yang, S.C.7
Jen, J.8
Sidransky, D.9
-
33
-
-
0027769876
-
A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4
-
Serrano M, Hannon GJ, Beach D (1993) A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4. Nature 366: 704-707
-
(1993)
Nature
, vol.366
, pp. 704-707
-
-
Serrano, M.1
Hannon, G.J.2
Beach, D.3
-
35
-
-
0028971961
-
INK4A inactivation in non-small cell lung cancer cell lines
-
INK4A inactivation in non-small cell lung cancer cell lines. Cancer Res 55: 6200-6209
-
(1995)
Cancer Res
, vol.55
, pp. 6200-6209
-
-
Shapiro, G.I.1
Park, J.E.2
Edwards, C.D.3
Mao, L.4
Merlo, A.5
Sidransky, K.6
Ewen, M.E.7
Rollins, B.J.8
-
36
-
-
0028171292
-
G1 phase progression: Cycling on cue
-
Sherr CJ (1994) G1 phase progression: cycling on cue. Cell 79: 551-555
-
(1994)
Cell
, vol.79
, pp. 551-555
-
-
Sherr, C.J.1
-
37
-
-
0013973616
-
X-ray sensitivity during the cell generation cycle of cultured chinese hamster cells
-
Sinclair WK, Morton RA (1966) X-ray sensitivity during the cell generation cycle of cultured Chinese hamster cells. Radiat Res 29: 450-474
-
(1966)
Radiat Res
, vol.29
, pp. 450-474
-
-
Sinclair, W.K.1
Morton, R.A.2
-
38
-
-
0029060657
-
Complex structure and regulation of the P16 (MTS1) locus
-
Stone S, Jiang P, Dayananth P, Tavtigian SV, Katcher H, Parry D, Peters G, Kamb A (1995) Complex structure and regulation of the P16 (MTS1) locus. Cancer Res 55: 2988-2994
-
(1995)
Cancer Res
, vol.55
, pp. 2988-2994
-
-
Stone, S.1
Jiang, P.2
Dayananth, P.3
Tavtigian, S.V.4
Katcher, H.5
Parry, D.6
Peters, G.7
Kamb, A.8
-
39
-
-
0000477631
-
X-ray sensitivity and DNA synthesis in synchronous populations of Hela cells
-
Terasima R, Tolmach LJ (1963) X-ray sensitivity and DNA synthesis in synchronous populations of Hela cells. Science 140: 490-492
-
(1963)
Science
, vol.140
, pp. 490-492
-
-
Terasima, R.1
Tolmach, L.J.2
-
40
-
-
0032569736
-
Expression of p16INK4a/p16alpha and p19ARF/p16beta is frequently altered in non-small cell lung cancer and correlates with p53 overexpression
-
Vonlanthen S, Heighway J, Tschan MP, Borner MM, Altermatt HJ, Kappeler A, Tobler A, Fey MF, Thatcher N, Yarbrough WG, Betticher DC (1998) Expression of p16INK4a/p16alpha and p19ARF/p16beta is frequently altered in non-small cell lung cancer and correlates with p53 overexpression. Oncogene 17: 2779-2785
-
(1998)
Oncogene
, vol.17
, pp. 2779-2785
-
-
Vonlanthen, S.1
Heighway, J.2
Tschan, M.P.3
Borner, M.M.4
Altermatt, H.J.5
Kappeler, A.6
Tobler, A.7
Fey, M.F.8
Thatcher, N.9
Yarbrough, W.G.10
Betticher, D.C.11
-
41
-
-
0029866249
-
Growth arrest and suppression of tumorigenicity of bladder carcinoma cell lines induced by the p16/CDKN2 gene and other loci on human chromosome 9
-
Wu Q, Possati L, Montesi M, Gualandi F, Rimessi P, Morelli C, Trabanelli C, Barbanti-Brodanao G (1996) Growth arrest and suppression of tumorigenicity of bladder carcinoma cell lines induced by the p16/CDKN2 gene and other loci on human chromosome 9. Int J Cancer 65: 840-846
-
(1996)
Int J Cancer
, vol.65
, pp. 840-846
-
-
Wu, Q.1
Possati, L.2
Montesi, M.3
Gualandi, F.4
Rimessi, P.5
Morelli, C.6
Trabanelli, C.7
Barbanti-Brodanao, G.8
-
42
-
-
0032549711
-
ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways
-
Zhang Y, Xiong Y, Yarbrough WG (1998) ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways. Cell 92: 725-734
-
(1998)
Cell
, vol.92
, pp. 725-734
-
-
Zhang, Y.1
Xiong, Y.2
Yarbrough, W.G.3
|