Differential processing and presentation of the H-2Db-restricted epitope from two different strains of influenza virus nucleoprotein

Journal of General Virology

Volumn 82, Issue 5, 2001, Pages 1069-1074

  Potter, Paul ^a,b   Tourdot, Sophie ^a   Blanchard, Tom ^c,d   Smith, Geoffrey L ^a,c   Gould, Keith G ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b IMPERIAL COLLEGE SCHOOL OF MEDICINE   (United Kingdom)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d MEDICAL RESEARCH COUNCIL LABORATORIES   (Gambia)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; EPITOPE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; VIRUS NUCLEOPROTEIN;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN PRESENTATION; ARTICLE; CONTROLLED STUDY; CROSS REACTION; CYTOLYSIS; CYTOTOXIC T LYMPHOCYTE; FEMALE; IN VITRO STUDY; INFLUENZA VIRUS; LYMPHOCYTE ACTIVATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROCESSING; SEQUENCE HOMOLOGY; TARGET CELL; VACCINIA VIRUS; VIRUS RECOMBINANT; VIRUS STRAIN;

ANIMALIA; INFLUENZA VIRUS; INFLUENZAVIRUS A; RNA VIRUSES; VACCINIA; VACCINIA VIRUS;

EID: 0035012038     PISSN: 00221317     EISSN: None     Source Type: Journal    
DOI: 10.1099/0022-1317-82-5-1069     Document Type: Article

References (24)

1. Antoine, G., Scheiflinger, F., Dorner, F. & Falkner, F. G. (1998). The complete genomic sequence of the modified vaccinia Ankara strain: comparison with other orthopoxviruses. Virology 244, 365-396.
2. Anton, L. C., Yewdell, J. W. & Bennink, J. R. (1997). MHC class I-associated peptides produced from endogenous gene products with vastly different efficiencies. Journal of Immunology 158, 2535-2542.
3. Bennink, J. R. & Yewdell, J. W. (1990). Recombinant vaccinia viruses as vectors for studying T lymphocyte specificity and function. Current Topics in Microbiology and Immunology 163, 153-184.
4. Blake, N. W., Kettle, S., Law, K. M., Gould, K., Bastin, J., Townsend, A. R. M. & Smith, G. L. (1995). Vaccinia virus serpins B13R and B22R do not inhibit antigen presentation to class I-restricted cytotoxic T lymphocytes. Journal of General Virology 76, 2393-2398.
5. Cerundolo, V., Tse, A. G. D., Salter, R. D., Parham, P. & Townsend, A. (1991). CD8 independence and specificity of cytotoxic T lymphocytes restricted by HLA-Aw68.I. Proceedings of the Royal Society of London Series B Biological Sciences 244, 169-177.
6. Cerundolo, V., Benham, A., Braud, V., Mukherjee, S., Gould, K., Macino, B., Neefjes, J. & Townsend, A. (1997). The proteasome-specific inhibitor lactacystin blocks presentation of cytotoxic T lymphocyte epitopes in human and murine cells. European Journal of Immunology 27, 336-341.
7. Chakrabarti, S., Brechling, K. & Moss, B. (1985). Vaccinia virus expression vector: coexpression of β-galactosidase provides visual screening of recombinant virus plaques. Molecular and Cellular Biology 5, 3403-3409.
8. k-restricted cytotoxic T cell epitope within the NSI protein of influenza virus using an MHC allele-specific motif. Virology 193, 289-295.
9. Coupar, B. E. H., Andrew, M. E., Both, G. W. & Boyle, D. B. (1986). Temporal regulation of influenza haemagglutinin expression in vaccinia virus recombinants and effects on the immune response. European Journal of Immunology 16, 1479-1487.
10. k-restricted T-cell epitopes within the influenza A/PR/8/34 virus hemagglutinin. Journal of Virology 65, 5401-5409.
11. + memory T cells by viral variants. Journal of Experimental Medicine 190, 1319-1328.
12. Hanke, T., Blanchard, T. J., Schneider, J., Ogg, G. S., Tan, R., Becker, M., Gilbert, S. C., Hill, A. V. S., Smith, G. L. & McMichael, A. (1998). Immunogenicities of intravenous and intramuscular administrations of modified vaccinia virus Ankara-based multi-CTL epitope vaccine for human immunodeficiency virus type 1 in mice. Journal of General Virology 79, 83-90.
13. Hill, A., Jugovic, P., York, I., Russ, G., Bennink, J., Yewdell, J., Ploegh, H. & Johnson, D. (1995). Herpes simplex virus turns off the TAP to evade host immunity. Nature 375, 411-415.
14. Miller, D. M. & Sedmak, D. D. (1999). Viral effects on antigen processing. Current Opinion in Immunology 11, 94-99.
15. Moss, B. (1968). Inhibition of HeLa cell protein synthesis by the vaccinia virion. Journal of Virology 2, 1028-1037.
16. + T cell induction and complete protective efficacy of malaria DNA vaccination by boosting with modified vaccinia virus Ankara. Nature Medicine 4, 397-402.
17. Schubert, U., Anton, L. C., Gibbs, J., Norbury, C. C., Yewdell, J. W. & Bennink, J. R. (2000). Rapid degradation of a large fraction of newly synthesized proteins by proteasomes. Nature 404, 770-774.
18. Smith, G. L., Levin, J. Z., Palese, P. & Moss, B. (1987). Synthesis and cellular location of the ten influenza polypeptides individually expressed by recombinant vaccinia viruses. Virology 160, 336-345.
19. Smith, G. L., Howard, S. T. & Chan, Y. S. (1989). Vaccinia virus encodes a family of genes with homology to serine proteinase inhibitors. Journal of General Virology 70, 2333-2343.
20. Tourdot, S., Oukka, M., Manuguerra, J. C., Magafa, V., Vergnon, I., Riche, N., Bruley-Rosset, M., Cordopatis, P. & Kosmatopoulos, K. (1997). Chimeric peptides: a new approach to enhancing the immunogenicity of peptides with low MHC class I affinity. Journal of Immunology 159, 2391-2398.
21. Townsend, A. R. M., McMichael, A. J., Carter, N. P., Huddleston, J. A. & Brownlee, G. G. (1984). Cytotoxic T cell recognition of the influenza nucleoprotein and hemagglutinin expressed in transfected mouse L cells. Cell 39, 13-25.
22. Townsend, A. R. M., Gotch, F. M. & Davey, J. (1985). Cytotoxic T cells recognize fragments of the influenza nucleoprotein. Cell 42, 457-467.
23. Townsend, A., Bastin, J., Gould, K., Brownlee, G., Andrew, M., Coupar, B., Boyle, D., Chan, S. & Smith, G. (1988). Defective presentation to class I-restricted cytotoxic T lymphocytes in vaccinia-infected cells is overcome by enhanced degradation of antigen. Journal of Experimental Medicine 168, 1211-1224.
24. Wiertz, E. J. H. J., Jones, T. R., Sun, L., Bogyo, M., Geuze, H. J. & Ploegh, H. L. (1996). The human cytomegalovirus US11 gene product dislocates MHC class 1 heavy chains from the endoplasmic reticulum to the cytosol. Cell 84, 769-779.