Increased osteoblast apoptosis in apert craniosynostosis role of protein kinase c and interleukin- 1

American Journal of Pathology

Volumn 158, Issue 5, 2001, Pages 1833-1842

  Lemonnier, Jérome ^a   Haÿ, Eric ^a   Delannoy, Philippe ^a   Fromigué, Olivia ^a   Lomri, Abderrahim ^a   Modrowski, Dominique ^a   Marie, Pierre J ^a  

^a HÔPITAL LARIBOISIÈRE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CALPHOSTIN C; CASPASE 3; CASPASE 6; CASPASE 7; CASPASE 8; DNA; FAS ANTIGEN; INTERLEUKIN 1; INTERLEUKIN 1 ANTIBODY; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; PROTEIN BAX; PROTEIN BCL 2; PROTEIN KINASE C;

ACROCEPHALOSYNDACTYLY; APOPTOSIS; ARTICLE; AUTOSOMAL DOMINANT DISORDER; CALVARIA; CONTROLLED STUDY; CRANIOFACIAL SYNOSTOSIS; CYTOKINE PRODUCTION; DNA DEGRADATION; FETUS; GENE MUTATION; HUMAN; HUMAN CELL; HUMAN TISSUE; NICK END LABELING; OSTEOBLAST; PRIORITY JOURNAL; PROTEIN EXPRESSION;

EID: 0035004860     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9440(10)64139-9     Document Type: Article

References (50)

1. Fibroblast-growth-factor receptor mutations in human skeletal disorders
2. FGF signaling in skeletal development
3. Fibroblast growth factor receptors: Lessons from the genes
4. Craniosynostosis syndromes: From genes to premature fusion of skull bones
5. Mutation associated with Crouzon syndrome causes ligand-independent dimerization and activation of FGF receptor-2
6. Activating mutations in the extracellular domain of the fibroblast growth factor 2 function by disruption of the disulfide bond in the third immunoglobulin-like domain
7. Crystal structures of two FGF-FGFR complexes reveal the determinants of ligand-receptor specificity
8. Increased calvaria cell differentiation and bone matrix formation induced by fibroblast growth factor receptor 2 mutations in Apert syndrome
9. The Ser252Trp fibroblast growth factor receptor-2 (FGFR-2) mutation induces PKC-independent downregulation of FGFR-2 associated with premature calvaria osteoblast differentiation
10. Decreased proliferation and altered differentiation in osteoblasts from genetically and clinically distinct craniosynostotic disorders
11. Role of N-cadherin and protein kinase C in osteoblast gene activation induced by the S252W fibroblast growth factor receptor 2 mutation in Apert craniosynostosis
12. Signaling by fibroblast growth factors (FGF) and fibroblast growth factor receptor 2 (FGFR2)-activating mutations blocks mineralization and induces apoptosis in osteoblasts
13. Sutural morphogenesis in the mouse calvaria: The role of apoptosis
14. Apoptotic cell death during normal embryogenesis of the coronal suture: Early detection of apoptosis in mice using annexin V
15. Apoptosis during bone-like tissue development in vitro
16. Apoptosis in murine calvarial bone and suture development
17. Birth and death of bone cells: Basic regulatory mechanisms and implications for the pathogenesis and treatment of osteoporosis
18. Apoptosis: The biochemistry and molecular biology of programmed cell death
19. Apoptosis
20. Serine/threonine protein kinases and apoptosis
21. The mitochondrion in cell death control: Certainties and incognita
22. Death receptors: Signaling and modulation
23. Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family
24. Involvement of the CD95 (APO-I/FAS) receptor/ligand system in drug-induced apoptosis in leukemia cells
25. Role of multiple cellular proteases in the execution of programmed cell death
26. Caspases: Enemies within
27. Bcl-2 and the regulation of programmed cell death
28. The Bcl-2 protein family
29. Fas and Fas ligand interaction is necessary, for human osteoblast apoptosis
30. Tumor necrosis factor-alpha and interleukin-1 beta increase the Fas-mediated apoptosis of human osteoblasts
31. Osteoblast programmed cell death (apoptosis): Modulation by growth factors and cytokines
32. Estrogen prevents glucocorticoid-induced apoptosis in osteoblasts in vivo and in vitro
33. Basic fibroblast growth factor induces apoptosis in myofibroblastic cells isolated from rat palatal mucosa
34. Basic fibroblast growth factor downregulates Bcl-2 and promotes apoptosis in MCF-7 human breast cancer cells
35. Increased bone formation and osteoblastic cell phenotype in premature cranial suture ossification (craniosynostosis)
36. 1α,25-dihydroxyvitamin D3 inhibits programmed cell death in HL-60 cells by activation of sphingosine kinase
37. Fibroblast growth factor receptor 3 mutations promote apoptosis but do not alter chondrocyte proliferation in thanatophoric dysplasia
38. FGF suppresses apoptosis and induces differentiation of fibre cells in the mouse lens
39. Protein kinase C involvement in apoptosis
40. Novel and classical protein kinase C isoforms have different functions in proliferation, survival and differentiation of neuroblastoma cells
41. Identification of genes induced by the Ser252Trp FGFR-2 Apert mutation in osteoblasts using atlas human expression arrays: Evidence for increased expression of PKCα, IL-1α and RhoA GTPase
42. Protein kinase C regulates Fas (CD95/APO-1) expression
43. Fas-induced apoptosis, and diseases caused by its abnormality
44. Fas and other cell death signaling pathways
45. An induced proximity, model for caspase-8 activation
46. Molecular ordering of the Fas-apoptotic pathway; the Fas/APO-1 protease Mch5 is a CrmA-inhibitable protease that activates multiple Ced-3/ICE-like cysteine proteases
47. Cell death induced by the Fas/Fas ligand pathway and its role in pathology
48. Fibroblast growth factors and osteoblasts
49. The effects of fibroblast growth factor-2 on human neonatal calvaria osteoblastic cells are differentiation stage specific
50. Fgfr1 and Fgfr2 have distinct differentiation- and proliferation-related roles in the developing mouse skull vault