Activating mutations in the extracellular domain of the fibroblast growth factor receptor 2 function by disruption of the disulfide bond in the third immunoglobulin-like domain

Proceedings of the National Academy of Sciences of the United States of America

Volumn 95, Issue 8, 1998, Pages 4567-4572

  Robertson, Scott C ^a   Meyer, April N ^a   Hart, Kristen C ^b   Galvin, Brendan D ^c   Webster, Melanie K ^a   Donoghue, Daniel J ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Crouzon syndrome; Neu chimera; Receptor activation

Indexed keywords

FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR RECEPTOR; PROTEIN TYROSINE KINASE;

ANIMAL CELL; ARTICLE; CELL TRANSFORMATION; DIMERIZATION; DISULFIDE BOND; EXTRACELLULAR MATRIX; MOLECULAR MODEL; MOUSE; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; ANIMALS; COS CELLS; CRANIOFACIAL DYSOSTOSIS; CYSTEINE; DIMERIZATION; DISULFIDES; HUMANS; IMMUNOGLOBULINS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUSCULOSKELETAL ABNORMALITIES; POINT MUTATION; PROTEIN STRUCTURE, SECONDARY; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTOR, FIBROBLAST GROWTH FACTOR, TYPE 2; RECEPTORS, FIBROBLAST GROWTH FACTOR; RECOMBINANT FUSION PROTEINS; RECOMBINANT PROTEINS; TRANSFECTION;

ANIMALIA;

EID: 0032515975     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.95.8.4567     Document Type: Article

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