메뉴 건너뛰기




Volumn 53, Issue 5, 2001, Pages 583-600

St John's wort (Hypericum perforatum L.): A review of its chemistry, pharmacology and clinical properties

Author keywords

[No Author keywords available]

Indexed keywords

ANTHRAQUINONE DERIVATIVE; ANTICONVULSIVE AGENT; ANTIDEPRESSANT AGENT; ANTIMIGRAINE AGENT; CYCLOSPORIN; DIGOXIN; FLAVONOID; FLUOXETINE; HYPERFORIN; HYPERICIN; HYPERICUM PERFORATUM EXTRACT; IMIPRAMINE; ORAL CONTRACEPTIVE AGENT; PLACEBO; PROTEINASE INHIBITOR; SEROTONIN UPTAKE INHIBITOR; SERTRALINE; THEOPHYLLINE; TRICYCLIC ANTIDEPRESSANT AGENT; WARFARIN;

EID: 0034998557     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1211/0022357011775910     Document Type: Review
Times cited : (693)

References (173)
  • 2
    • 0002513561 scopus 로고
    • St John's wort extract in the treatment of depression: Observations of the use of Jarsin capsules
    • Albrecht, M., Hübner, W. O., Podzuweit, H., Schmidt, U. (1994) St John's wort extract in the treatment of depression: observations of the use of Jarsin capsules. Der Kassenarzt 41: 45-54
    • (1994) Der Kassenarzt , vol.41 , pp. 45-54
    • Albrecht, M.1    Hübner, W.O.2    Podzuweit, H.3    Schmidt, U.4
  • 3
    • 0002342461 scopus 로고    scopus 로고
    • St John's wort. Hypericum perforatum
    • Quality control, analytical and therapeutic monograph. American Botanical Council, Texas
    • American Herbal Pharmacopeia (1997) St John's wort. Hypericum perforatum. Quality control, analytical and therapeutic monograph. American Botanical Council, Texas
    • (1997) American Herbal Pharmacopeia
  • 4
    • 0018783011 scopus 로고
    • Toxic reactions to plant products sold in health food stores
    • Anon. (1979) Toxic reactions to plant products sold in health food stores. Med. Lett. Drugs Ther. 21: 29-30
    • (1979) Med. Lett. Drugs Ther. , vol.21 , pp. 29-30
  • 5
    • 0343307453 scopus 로고
    • Hypericin improves blood safety?
    • Anon. (1995a) Hypericin improves blood safety? Scrip 2005: 27
    • (1995) Scrip , vol.2005 , pp. 27
  • 6
    • 0342872403 scopus 로고
    • Hypericin HIV trial in Thailand
    • Anon. (1995b) Hypericin HIV trial in Thailand. Scrip 2019: 25
    • (1995) Scrip , vol.2019 , pp. 25
  • 7
    • 0010414331 scopus 로고    scopus 로고
    • CSM advice on St John's wort
    • Anon. (2000) CSM advice on St John's wort. Pharm. J. 264: 358
    • (2000) Pharm. J. , vol.264 , pp. 358
  • 8
    • 0022884970 scopus 로고
    • A comparative study of phenolic acids of Hypericum caprifolium Boiss and Hypericum perforatum L
    • Ayuga, C., Rebuelta, M. (1986) A comparative study of phenolic acids of Hypericum caprifolium Boiss and Hypericum perforatum L. An. Real Acad. Farm. 52: 723-728
    • (1986) An. Real Acad. Farm. , vol.52 , pp. 723-728
    • Ayuga, C.1    Rebuelta, M.2
  • 9
    • 0013493275 scopus 로고    scopus 로고
    • Hypericum - Four hypersensitivity reactions
    • Baillie, N. (1997) Hypericum - four hypersensitivity reactions. The Modern Phytotherapist 3: 24-26
    • (1997) The Modern Phytotherapist , vol.3 , pp. 24-26
    • Baillie, N.1
  • 10
    • 0018375216 scopus 로고
    • Alcohol and central serotonin metabolism in man
    • Ballenger, J. C., Godwin, F. K., Major, L. F., Brown, G. L. (1979) Alcohol and central serotonin metabolism in man. Arch Gen Psych Scand 57:224-227. Cited by Rezvani AH, Overstreet, D. H., Yang, Y., Clarke, E. (1999). Attenuation of alcohol intake by extract of Hypericum perforatum (St John's wort) in two different strains of alcohol-preferring rats. Alcohol Alcohol. 34: 699-705
    • (1979) Arch Gen Psych Scand , vol.57 , pp. 224-227
    • Ballenger, J.C.1    Godwin, F.K.2    Major, L.F.3    Brown, G.L.4
  • 11
    • 0032871950 scopus 로고    scopus 로고
    • Attenuation of alcohol intake by extract of Hypericum perforatum (St John's wort) in two different strains of alcohol-preferring rats
    • Ballenger, J. C., Godwin, F. K., Major, L. F., Brown, G. L. (1979) Alcohol and central serotonin metabolism in man. Arch Gen Psych Scand 57:224-227. Cited by Rezvani AH, Overstreet, D. H., Yang, Y., Clarke, E. (1999). Attenuation of alcohol intake by extract of Hypericum perforatum (St John's wort) in two different strains of alcohol-preferring rats. Alcohol Alcohol. 34: 699-705
    • (1999) Alcohol Alcohol , vol.34 , pp. 699-705
    • Rezvani, A.H.1    Overstreet, D.H.2    Yang, Y.3    Clarke, E.4
  • 12
    • 0034020386 scopus 로고    scopus 로고
    • Mania in a patient receiving testosterone replacement post-orchidectomy taking St John's wort and sertraline
    • Barbenel, D. M., Yusufi, B., O'Shea, D., Bench, C. J. (2000) Mania in a patient receiving testosterone replacement post-orchidectomy taking St John's wort and sertraline. J. Psychopharmacol. 14: 84-86
    • (2000) J. Psychopharmacol. , vol.14 , pp. 84-86
    • Barbenel, D.M.1    Yusufi, B.2    O'Shea, D.3    Bench, C.J.4
  • 15
    • 0034106493 scopus 로고    scopus 로고
    • Consumer use of St John's wort: A survey on effectiveness, safety and tolerability
    • Beckman, S. E., Roger, W. S., Switzer, J. (2000) Consumer use of St John's wort: a survey on effectiveness, safety and tolerability. Pharmacotherapy 20: 568-574
    • (2000) Pharmacotherapy , vol.20 , pp. 568-574
    • Beckman, S.E.1    Roger, W.S.2    Switzer, J.3
  • 16
    • 0023135318 scopus 로고
    • Biflavonoids in Hypericum perforatum; Part 1. Isolation of 13,II8-biapigenin
    • Berghöfer, R., Hölzl, J. (1987) Biflavonoids in Hypericum perforatum; Part 1. Isolation of 13,II8-biapigenin. Planta Med. 53: 216-217
    • (1987) Planta Med. , vol.53 , pp. 216-217
    • Berghöfer, R.1    Hölzl, J.2
  • 17
    • 0024505531 scopus 로고
    • Isolation of I3′,II8-biapigenin (amentoflavone) from Hypericum perforatum
    • Berghöfer, R., Hölzl, J. (1989) Isolation of I3′,II8-biapigenin (amentoflavone) from Hypericum perforatum. Planta Med. 55: 91
    • (1989) Planta Med. , vol.55 , pp. 91
    • Berghöfer, R.1    Hölzl, J.2
  • 18
    • 13044263873 scopus 로고    scopus 로고
    • Effect of dianthrones and their precursors from Hypericum perforatum L. on lipoxygenase activity
    • Bezáková, L., Psenak, M., Kartnig, T. (1999) Effect of dianthrones and their precursors from Hypericum perforatum L. on lipoxygenase activity. Pharmazie 54: 711
    • (1999) Pharmazie , vol.54 , pp. 711
    • Bezáková, L.1    Psenak, M.2    Kartnig, T.3
  • 19
    • 0031779971 scopus 로고    scopus 로고
    • Oral bioavailability of hyperforin from hypericum extracts in rats and human volunteers
    • Biber, A., Fischer, H., Romer, A., Chatterjee, S. S. (1998) Oral bioavailability of hyperforin from hypericum extracts in rats and human volunteers. Pharmacopsychiatry 31(Suppl 1): 36-43
    • (1998) Pharmacopsychiatry , vol.31 , Issue.1 SUPPL. , pp. 36-43
    • Biber, A.1    Fischer, H.2    Romer, A.3    Chatterjee, S.S.4
  • 20
  • 21
    • 0028154811 scopus 로고
    • Inhibition of MAO by fractions and constituents of Hypericum extract
    • Bladt S, Wagner, H. (1994) Inhibition of MAO by fractions and constituents of Hypericum extract. J Geriatric Psychiatry Neurology 7: S57-59
    • (1994) J Geriatric Psychiatry Neurology , vol.7
    • Bladt, S.1    Wagner, H.2
  • 22
    • 0343743006 scopus 로고    scopus 로고
    • Benefit of a fixed drug combination containing St John's wort and black cohosh for climacteric patients - Results of a randomised clinical trial
    • Boblitz, N., Schrader, E., Henneicke-von Zepelin, H-H., Wüstenberg, P. (2000) Benefit of a fixed drug combination containing St John's wort and black cohosh for climacteric patients - results of a randomised clinical trial [abstract]. FACT 5: 85
    • (2000) FACT , vol.5 , pp. 85
    • Boblitz, N.1    Schrader, E.2    Henneicke-Von Zepelin, H.-H.3    Wüstenberg, P.4
  • 25
    • 0032480534 scopus 로고    scopus 로고
    • Acute neuropathy after exposure to sun in a patient treated with St John's wort
    • Bove, G. M. (1998) Acute neuropathy after exposure to sun in a patient treated with St John's wort. Lancet 352: 1121-1122
    • (1998) Lancet , vol.352 , pp. 1121-1122
    • Bove, G.M.1
  • 28
    • 0034124646 scopus 로고    scopus 로고
    • Comparison of an extract of hypericum (LI160) and sertraline in the treatment of depression : A double-blind, randomized pilot study
    • Brenner, R., Azbel, V., Madhusoodanan, S., Pawlowska, M. (2000) Comparison of an extract of hypericum (LI160) and sertraline in the treatment of depression : a double-blind, randomized pilot study. Clin. Ther. 22: 411-419
    • (2000) Clin. Ther. , vol.22 , pp. 411-419
    • Brenner, R.1    Azbel, V.2    Madhusoodanan, S.3    Pawlowska, M.4
  • 29
    • 0002490743 scopus 로고    scopus 로고
    • The booming US botanical market. A new overview
    • Brevoort, P. (1998) The booming US botanical market. A new overview. Herbalgram 44: 33-46
    • (1998) Herbalgram , vol.44 , pp. 33-46
    • Brevoort, P.1
  • 30
    • 0003999936 scopus 로고    scopus 로고
    • Exeter: British Herbal Medicine Association
    • British Herbal Pharmacopoeia (1996) Exeter: British Herbal Medicine Association
    • (1996) British Herbal Pharmacopoeia
  • 31
    • 0030761151 scopus 로고    scopus 로고
    • Hypericin and pseudohypericin : Pharmacokinetics and effects on photosensitivity in humans
    • Brockmöller, J., Reum, T., Bauer, S., Kerb, R., Hübner, W. D., Roots, I. (1997) Hypericin and pseudohypericin : pharmacokinetics and effects on photosensitivity in humans. Pharmacopsychiatry 30(Suppl): 94-101
    • (1997) Pharmacopsychiatry , vol.30 , Issue.SUPPL. , pp. 94-101
    • Brockmöller, J.1    Reum, T.2    Bauer, S.3    Kerb, R.4    Hübner, W.D.5    Roots, I.6
  • 32
    • 0019953489 scopus 로고
    • The relative stereochemistry of hyperforin an antibiotic from Hypericum perforatum L
    • Brondz, I., Greibrokk, T., Groth, P. A., Aasen, A. J. (1982) The relative stereochemistry of hyperforin An antibiotic from Hypericum perforatum L. Tetrahedron Lett. 1 23: 1299-1300
    • (1982) Tetrahedron Lett. 1 , vol.23 , pp. 1299-1300
    • Brondz, I.1    Greibrokk, T.2    Groth, P.A.3    Aasen, A.J.4
  • 33
    • 0000227717 scopus 로고
    • n-Alkanes of Hypericum perforation: A revision
    • Brondz, I., Greybrok, T., Aasen, A. J. (1983) n-Alkanes of Hypericum perforation: A revision. Phytochemistry 22: 295-296
    • (1983) Phytochemistry , vol.22 , pp. 295-296
    • Brondz, I.1    Greybrok, T.2    Aasen, A.J.3
  • 34
    • 0033963119 scopus 로고    scopus 로고
    • Flavonoids from Hypericum perforatum show antidepressant activity in the forced swimming test
    • Butterweck, V., Jurgenliemk, G., Nahrstedt, A., Winterhoff, H. (2000) Flavonoids from Hypericum perforatum show antidepressant activity in the forced swimming test. Planta Med. 66: 3-6
    • (2000) Planta Med. , vol.66 , pp. 3-6
    • Butterweck, V.1    Jurgenliemk, G.2    Nahrstedt, A.3    Winterhoff, H.4
  • 35
    • 0032765281 scopus 로고    scopus 로고
    • Effects of Hypericum perforatum on levels of 5-hydroxytryptamine, noradrenaline and dopamine in the cortex, diencephalon and brainstem of the rat
    • Calapai, G., Crupi, A., Firenzuoli, F., Costantino, G., Inferrera, G., Campo, G. M., Caputi, A. P. (1999) Effects of Hypericum perforatum on levels of 5-hydroxytryptamine, noradrenaline and dopamine in the cortex, diencephalon and brainstem of the rat. J. Pharm. Pharmacol. 51: 723-728
    • (1999) J. Pharm. Pharmacol. , vol.51 , pp. 723-728
    • Calapai, G.1    Crupi, A.2    Firenzuoli, F.3    Costantino, G.4    Inferrera, G.5    Campo, G.M.6    Caputi, A.P.7
  • 37
    • 0031748869 scopus 로고    scopus 로고
    • Antidepressant activity of Hypericum perforatum and hyperforin: The neglected possibility
    • Chatterjee, S.S., Noldner, M., Koch, E., Erdelmeier, C. (1998b) Antidepressant activity of Hypericum perforatum and hyperforin: the neglected possibility. Pharmacopsychiatry 31(Suppl): 7-15
    • (1998) Pharmacopsychiatry , vol.31 , Issue.SUPPL. , pp. 7-15
    • Chatterjee, S.S.1    Noldner, M.2    Koch, E.3    Erdelmeier, C.4
  • 40
    • 0032999912 scopus 로고    scopus 로고
    • Effects of Citrus aurantium extract, caffeine, and St John's wort on body fat loss, lipid levels, and mood states in overweight healthy adults
    • Colker, C. M., Kalman, D. S., Torina, G. C., Perlis, T., Street, C. (1999) Effects of Citrus aurantium extract, caffeine, and St John's wort on body fat loss, lipid levels, and mood states in overweight healthy adults. Curr. Ther. Res. 60: 145-153
    • (1999) Curr. Ther. Res. , vol.60 , pp. 145-153
    • Colker, C.M.1    Kalman, D.S.2    Torina, G.C.3    Perlis, T.4    Street, C.5
  • 41
    • 0343307441 scopus 로고
    • An observational study of the safety and efficacy of hypericin in HIV-positive subjects
    • Cooper, W. C., James, J. (1990) An observational study of the safety and efficacy of hypericin in HIV-positive subjects [abstract]. International Conference on AIDS 6: 369
    • (1990) International Conference on AIDS , vol.6 , pp. 369
    • Cooper, W.C.1    James, J.2
  • 42
    • 0030881089 scopus 로고    scopus 로고
    • In vitro receptor binding and enzyme inhibition by Hypericum perforatum extract
    • Cott, J. M. (1997) In vitro receptor binding and enzyme inhibition by Hypericum perforatum extract. Pharmacopsychiatry 30(Suppl): 108-112
    • (1997) Pharmacopsychiatry , vol.30 , Issue.SUPPL. , pp. 108-112
    • Cott, J.M.1
  • 43
    • 0343743001 scopus 로고    scopus 로고
    • Report No. 1 Strasbourg: Council of Europe
    • Council of Europe (2000) Natural sources of Flavourings. Report No. 1 Strasbourg: Council of Europe
    • (2000) Natural Sources of Flavourings
  • 44
    • 0024469955 scopus 로고
    • Identification of MAO-type-A inhibitors in Hypericum perforatum L. (Hyperforat)
    • Demisch, L., Hölzl, J., Golnik, B., Kacynarczyk, P. (1989) Identification of MAO-type-A inhibitors in Hypericum perforatum L. (Hyperforat). Pharmacopsychiatry 22: 194
    • (1989) Pharmacopsychiatry , vol.22 , pp. 194
    • Demisch, L.1    Hölzl, J.2    Golnik, B.3    Kacynarczyk, P.4
  • 45
    • 0033383134 scopus 로고    scopus 로고
    • Comparison of hypericum extracts with imipramine and fluoxetine in animal models of depression and alcoholism
    • De Vry, J., Maurel, S., Schreiber, R., de Beun, R., Jentzsch, K. R. (1999) Comparison of hypericum extracts with imipramine and fluoxetine in animal models of depression and alcoholism. Eur. Neuropsychopharmacol. 9: 461-468
    • (1999) Eur. Neuropsychopharmacol. , vol.9 , pp. 461-468
    • De Vry, J.1    Maurel, S.2    Schreiber, R.3    De Beun, R.4    Jentzsch, K.R.5
  • 47
    • 0022404472 scopus 로고
    • Determination of flavonoids in Hypericum perforatum
    • Dorossiev, I. (1985) Determination of flavonoids in Hypericum perforatum. Pharmazie 40: 585-586
    • (1985) Pharmazie , vol.40 , pp. 585-586
    • Dorossiev, I.1
  • 48
    • 0022730534 scopus 로고
    • Hypericin and its photodynamic action
    • Durán, N., Song, P-S. (1986) Hypericin and its photodynamic action. Photochem. Photobiol. 43: 677-680
    • (1986) Photochem. Photobiol. , vol.43 , pp. 677-680
    • Durán, N.1    Song, P.-S.2
  • 50
    • 0031741887 scopus 로고    scopus 로고
    • Adverse effects profile of the herbal antidepressant St John's wort (Hypericum perforatum L.)
    • Ernst, E., Rand, J. I., Barnes, J., Stevinson, C. (1998) Adverse effects profile of the herbal antidepressant St John's wort (Hypericum perforatum L.). Eur J. Clin. Pharmacol. 54: 589-594
    • (1998) Eur J. Clin. Pharmacol. , vol.54 , pp. 589-594
    • Ernst, E.1    Rand, J.I.2    Barnes, J.3    Stevinson, C.4
  • 51
    • 0342872391 scopus 로고    scopus 로고
    • Strasbourg: Masionneuve
    • European Pharmacopoeia 2000 (Suppl). Strasbourg: Masionneuve, 2000
    • (2000) European Pharmacopoeia 2000 , Issue.SUPPL.
  • 52
    • 0342437880 scopus 로고    scopus 로고
    • St john's wort. Monographs on the medicinal use of plant drugs. Fascicule 1
    • European Scientific Cooperative on phytotherapy. (1996) St John's wort. Monographs on the medicinal use of plant drugs. Fascicule 1. Hyperici herba.
    • (1996) Hyperici Herba
  • 55
    • 0342872387 scopus 로고    scopus 로고
    • Alltagssicherheit eines pflanzlichen antidepressivums aus johanniskraut
    • Friede, M., Hasenfuss, I., Wüstenberg, P. (1998) Alltagssicherheit eines pflanzlichen Antidepressivums aus Johanniskraut. Fortschritte der Medizin 116: 31-135
    • (1998) Fortschritte der Medizin , vol.116 , pp. 31-135
    • Friede, M.1    Hasenfuss, I.2    Wüstenberg, P.3
  • 58
    • 0020071407 scopus 로고
    • Consumption of poisonous plants (Senecio jacobaea, Symphytum officinale, Pteridium aquilinum, Hypericum perforatum) by rats: Chronic toxicity, mineral metabolism, and hepatic drug-metabolizing enzymes
    • Garrett, B. J., Cheeke, P. R., Miranda, C. L., Goeger, D. E., Buhler, D. R. (1982) Consumption of poisonous plants (Senecio jacobaea, Symphytum officinale, Pteridium aquilinum, Hypericum perforatum) by rats: chronic toxicity, mineral metabolism, and hepatic drug-metabolizing enzymes. Toxicol. Lett. 10: 183-188
    • (1982) Toxicol. Lett. , vol.10 , pp. 183-188
    • Garrett, B.J.1    Cheeke, P.R.2    Miranda, C.L.3    Goeger, D.E.4    Buhler, D.R.5
  • 62
    • 0032032735 scopus 로고    scopus 로고
    • SSRIs and St John's wort : Possible toxicity?
    • Gordon, J. B. (1998) SSRIs and St John's wort : possible toxicity? Am. Fam. Phys. 57: 950-953
    • (1998) Am. Fam. Phys. , vol.57 , pp. 950-953
    • Gordon, J.B.1
  • 63
    • 0032695126 scopus 로고    scopus 로고
    • St John's wort extract: Efficacy for menopausal symptoms of psychological origin
    • Grube, B., Walper, A., Wheatley, D. (1999) St John's wort extract: efficacy for menopausal symptoms of psychological origin. Adv. Ther. 16: 177-186
    • (1999) Adv. Ther. , vol.16 , pp. 177-186
    • Grube, B.1    Walper, A.2    Wheatley, D.3
  • 64
    • 0000159374 scopus 로고    scopus 로고
    • Use of a hypericum extract in mild, transient depressive mood disorders
    • Grube, B., Schermuck, S., Hopfenmüller, W., Michel, F. (1997) Use of a hypericum extract in mild, transient depressive mood disorders. Eur. J. Clin. Res. 9: 293-302
    • (1997) Eur. J. Clin. Res. , vol.9 , pp. 293-302
    • Grube, B.1    Schermuck, S.2    Hopfenmüller, W.3    Michel, F.4
  • 65
    • 84882562734 scopus 로고
    • The examining of isolated tannins and their astringent effect
    • Grujic-Vasic, J., Bosnić, T., Jovanović, M. (1986) The examining of isolated tannins and their astringent effect. Planta Med 52 (Suppl.): 67-68
    • (1986) Planta Med , vol.52 , Issue.SUPPL. , pp. 67-68
    • Grujic-Vasic, J.1    Bosnić, T.2    Jovanović, M.3
  • 68
    • 0032947468 scopus 로고    scopus 로고
    • Comparison of equivalence between the St John's wort extract LoHyp-57 and fluoxetine
    • Harrer, G., Schmidt, U., Kuhn, U., Biller, A. (1999) Comparison of equivalence between the St John's wort extract LoHyp-57 and fluoxetine. Arzneim-Forsch 49: 289-296
    • (1999) Arzneim-Forsch , vol.49 , pp. 289-296
    • Harrer, G.1    Schmidt, U.2    Kuhn, U.3    Biller, A.4
  • 69
  • 70
    • 0000354045 scopus 로고
    • St John's wort (Hypericum perforatum L.). HPLC analysis of the main components and their variability in a population
    • Hoelzl, J., Ostrowski, E. (1987) St John's wort (Hypericum perforatum L.). HPLC analysis of the main components and their variability in a population. Deutsch Apoth Ztg 127: 1227-1230
    • (1987) Deutsch Apoth Ztg , vol.127 , pp. 1227-1230
    • Hoelzl, J.1    Ostrowski, E.2
  • 71
    • 4243332921 scopus 로고    scopus 로고
    • Efficacy and tolerability of the hypericum special extract LI 160 in young and elderly outpatients with depressive disorders: A drug monitoring study
    • Holsboer-Trachsler, E., Henauer, S., Vanoni, C. H. (1999) Efficacy and tolerability of the hypericum special extract LI 160 in young and elderly outpatients with depressive disorders: a drug monitoring study. Eur Neuropsychopharmacology 9(Suppl 5): S226
    • (1999) Eur Neuropsychopharmacology , vol.9 , Issue.5 SUPPL.
    • Holsboer-Trachsler, E.1    Henauer, S.2    Vanoni, C.H.3
  • 72
    • 0342437874 scopus 로고    scopus 로고
    • The influence of vitamin E and extract from hypericum on the endurance capacity of competitors. A placebo-controlled double-blind study with long-distance runners and triathletes
    • Hottenrot, K., Sommer, H-M., Lehrl, S., Hauer, H. (1997) The influence of vitamin E and extract from hypericum on the endurance capacity of competitors. A placebo-controlled double-blind study with long-distance runners and triathletes. Deutsche seitschrift für Sportmedizin 48: 22-27
    • (1997) Deutsche Seitschrift für Sportmedizin , vol.48 , pp. 22-27
    • Hottenrot, K.1    Sommer, H.-M.2    Lehrl, S.3    Hauer, H.4
  • 74
    • 0342872385 scopus 로고
    • Hypericin - A plant extract with anti-HIV activity
    • Hypericin - a plant extract with anti-HIV activity. Scrip 1989; 1415: 29
    • (1989) Scrip , vol.1415 , pp. 29
  • 75
    • 0343307411 scopus 로고    scopus 로고
    • Herbal products are driving supplement industry growth
    • Isenberg, L. (1998) Herbal products are driving supplement industry growth. Herbalgram 42: 65
    • (1998) Herbalgram , vol.42 , pp. 65
    • Isenberg, L.1
  • 76
    • 0000006828 scopus 로고    scopus 로고
    • Pharmacokinetic interaction of digoxin with an herbal extract from St John's wort (Hypericum perforatum)
    • Johne, A., Brockmoller, J., Bauer, S., Maurer, A., Langheinrich, M., Roots, I. (1999) Pharmacokinetic interaction of digoxin with an herbal extract from St John's wort (Hypericum perforatum). Clin. Pharmacol. Ther. 66: 338-345
    • (1999) Clin. Pharmacol. Ther. , vol.66 , pp. 338-345
    • Johne, A.1    Brockmoller, J.2    Bauer, S.3    Maurer, A.4    Langheinrich, M.5    Roots, I.6
  • 79
    • 0034126080 scopus 로고    scopus 로고
    • Investigation of the absorption of hypericin into the skin of hairless mice
    • Kamuhabwa, A. R., Geboes, K. R., de Witte, P. A. (2000a) Investigation of the absorption of hypericin into the skin of hairless mice. J. Pharm. Pharmacol. 52: 487-494
    • (2000) J. Pharm. Pharmacol. , vol.52 , pp. 487-494
    • Kamuhabwa, A.R.1    Geboes, K.R.2    De Witte, P.A.3
  • 81
    • 0030801885 scopus 로고    scopus 로고
    • Treatment of seasonal affective disorder (SAD) with hypericum extract
    • Kasper, S. (1997) Treatment of seasonal affective disorder (SAD) with hypericum extract. Pharmacopsychiatry 30(Suppl): 89-93
    • (1997) Pharmacopsychiatry , vol.30 , Issue.SUPPL. , pp. 89-93
    • Kasper, S.1
  • 82
    • 26144475431 scopus 로고    scopus 로고
    • Efficacy and tolerability of the St John's wort extract (Ze 117) in comparison with placebo, imipramine and fluoxetine for the treatment of mild to moderate depression according to ICD-10
    • February Frankfurt, Germany
    • Käufeler, R., Meier, B., Brattström, A. Efficacy and tolerability of the St John's wort extract (Ze 117) in comparison with placebo, imipramine and fluoxetine for the treatment of mild to moderate depression according to ICD-10 [abstract]. Biocenter Symposium on Drug Therapy. Pharmacology of St. John's wort (Hypericum perforatum L.) and its constituents. February 2000, Frankfurt, Germany.
    • (2000) Biocenter Symposium on Drug Therapy. Pharmacology of St. John's Wort (Hypericum Perforatum L.) and Its Constituents
    • Käufeler, R.1    Meier, B.2    Brattström, A.3
  • 83
    • 0000248189 scopus 로고    scopus 로고
    • Urinary 6-beta-hydroxycortisol excretion rate is affected by treatment with hypericum extract
    • Kerb, R., Bayer, S., Brockmöller, J., Roots, I. (1997) Urinary 6-beta-hydroxycortisol excretion rate is affected by treatment with hypericum extract. Eur. J. Clin. Pharmacol. 52: 607
    • (1997) Eur. J. Clin. Pharmacol. , vol.52 , pp. 607
    • Kerb, R.1    Bayer, S.2    Brockmöller, J.3    Roots, I.4
  • 84
    • 0032881183 scopus 로고    scopus 로고
    • St John's wort for depression. A meta-analysis of well-defined clinical trials
    • Kim, H. L., Streltzer, J., Goebert, D. (1999) St John's wort for depression. A meta-analysis of well-defined clinical trials. J. Nerv. Ment. Dis. 187: 532-539
    • (1999) J. Nerv. Ment. Dis. , vol.187 , pp. 532-539
    • Kim, H.L.1    Streltzer, J.2    Goebert, D.3
  • 86
    • 0034284697 scopus 로고    scopus 로고
    • Effect of Indian Hypericum perforatum linn on animal models of cognitive dysfunction
    • Kumar, V., Singh, P. N., Muruganandam, A. V., Bhattacharya, S. K. (2000) Effect of Indian Hypericum perforatum Linn on animal models of cognitive dysfunction. J. Ethnopharmacol. 72: 119-128
    • (2000) J. Ethnopharmacol. , vol.72 , pp. 119-128
    • Kumar, V.1    Singh, P.N.2    Muruganandam, A.V.3    Bhattacharya, S.K.4
  • 88
    • 0031747773 scopus 로고    scopus 로고
    • St john's wort in mild to moderate depression: The relevance of hyperforin for the clinical efficacy
    • Laakmann, G., Schüle, C., Baghai, T., Kieser, M. (1998) St John's wort in mild to moderate depression: the relevance of hyperforin for the clinical efficacy. Pharmacopsychiatry 31(Suppl): 54-59
    • (1998) Pharmacopsychiatry , vol.31 , Issue.SUPPL. , pp. 54-59
    • Laakmann, G.1    Schüle, C.2    Baghai, T.3    Kieser, M.4
  • 89
    • 0034689551 scopus 로고    scopus 로고
    • Photosensitivity associated with herbal preparations of St John's wort (Hypericum perforatum)
    • Lane-Brown, M. M. (2000) Photosensitivity associated with herbal preparations of St John's wort (Hypericum perforatum). Med J Aust 172: 302
    • (2000) Med J Aust , vol.172 , pp. 302
    • Lane-Brown, M.M.1
  • 90
  • 93
    • 0033159216 scopus 로고    scopus 로고
    • A double-blind randomised trial to investigate three different concentrations of a standardised fresh plant extract obtained from the shoot tips of Hypericum perforatum L
    • Lenoir, S., Degenring, F. H., Saller, R. (1999) A double-blind randomised trial to investigate three different concentrations of a standardised fresh plant extract obtained from the shoot tips of Hypericum perforatum L., Phytomedicine 6: 141-146
    • (1999) Phytomedicine , vol.6 , pp. 141-146
    • Lenoir, S.1    Degenring, F.H.2    Saller, R.3
  • 94
    • 0033547632 scopus 로고    scopus 로고
    • Commentary: Has hypericum found its place in antidepressant treatment?
    • Linde, K., Berner, M. (1999) Commentary: Has hypericum found its place in antidepressant treatment? BMJ 319: 1539
    • (1999) BMJ , vol.319 , pp. 1539
    • Linde, K.1    Berner, M.2
  • 95
    • 21844437994 scopus 로고    scopus 로고
    • St John's wort for depression
    • Oxford: Update Software
    • Linde, K., Mulrow, C. D. (2001) St John's wort for depression (Cochrane Review). In: The Cochrane Library. Issue 1, Oxford: Update Software
    • (2001) The Cochrane Library , Issue.1
    • Linde, K.1    Mulrow, C.D.2
  • 96
    • 0030055770 scopus 로고    scopus 로고
    • St John's wort for depression - An overview and meta-analysis of randomised clinical trials
    • Linde, K., Ramirez, G., Mulrow, C. D., Pauls, A., Weidenhammer, W., Melchart, D. (1996) St John's wort for depression - an overview and meta-analysis of randomised clinical trials. BMJ 313: 253-258
    • (1996) BMJ , vol.313 , pp. 253-258
    • Linde, K.1    Ramirez, G.2    Mulrow, C.D.3    Pauls, A.4    Weidenhammer, W.5    Melchart, D.6
  • 97
    • 0033850464 scopus 로고    scopus 로고
    • Hypericin and photodynamic therapy decreases human pancreatic cancer in vitro and in vivo
    • Liu, C. D., Kwan, D., Saxton, R. E., McFadden, D. W. (2000) Hypericin and photodynamic therapy decreases human pancreatic cancer in vitro and in vivo. J. Surg. Res. 93: 137-143
    • (2000) J. Surg. Res. , vol.93 , pp. 137-143
    • Liu, C.D.1    Kwan, D.2    Saxton, R.E.3    McFadden, D.W.4
  • 99
    • 0034695608 scopus 로고    scopus 로고
    • Effect of St John's wort (Hypericum perforatum) on cytochrome P450 2D6 and 3A4 activity in healthy volunteers
    • Markowitz, J. S., Devane, C. L., Boulton, D. W., Carson, S. W., Nahas, Z, Risch, S. C. (2000) Effect of St John's wort (Hypericum perforatum) on cytochrome P450 2D6 and 3A4 activity in healthy volunteers. Life Sci. 66: 133-139
    • (2000) Life Sci. , vol.66 , pp. 133-139
    • Markowitz, J.S.1    Devane, C.L.2    Boulton, D.W.3    Carson, S.W.4    Nahas, Z.5    Risch, S.C.6
  • 100
    • 0001477181 scopus 로고
    • Étude chimio-taxonomique du genre hypericum - II. Identification de constituants de diverses huiles essentielles d'Hypericum
    • Mathis, C., Ourisson, G. (1964a) Étude chimio-taxonomique du genre Hypericum - II. Identification de constituants de diverses huiles essentielles d'Hypericum. Phytochemistry 3: 115-131
    • (1964) Phytochemistry , vol.3 , pp. 115-131
    • Mathis, C.1    Ourisson, G.2
  • 101
    • 0001477184 scopus 로고
    • Étude chimio-taxonomique du genre hypericum - IV. Repartition des sesquiterpenes, des alcools monoterpeniques et des aldehydes satures dans les huiles essentielles d'Hypericum
    • Mathis, C., Ourisson, G. (1964b) Étude chimio-taxonomique du genre Hypericum - IV. Repartition des sesquiterpenes, des alcools monoterpeniques et des aldehydes satures dans les huiles essentielles d'Hypericum. Phytochemistry 3: 377-378
    • (1964) Phytochemistry , vol.3 , pp. 377-378
    • Mathis, C.1    Ourisson, G.2
  • 102
    • 0002892705 scopus 로고
    • Étude chimio-taxonomique du genre hypericum - V. Identification de quelques constituants non volatils d'Hypericum perforatum L
    • Mathis, C., Ourisson, G. (1964e) Étude chimio-taxonomique du genre Hypericum - V. Identification de quelques constituants non volatils d'Hypericum perforatum L. Phytochemistry 3: 379
    • (1964) Phytochemistry , vol.3 , pp. 379
    • Mathis, C.1    Ourisson, G.2
  • 104
    • 0002662558 scopus 로고    scopus 로고
    • Wirksamkeit und verträglichkeit eines standardisierten johanniskraut-vollextraktes (ze 117) bei patienten mit depressiver symptomatik unterschiedlicher schweregrade eine anwendungsbeobachtung
    • Meier, B., Liske, E., Rosinus, V. (1997) Wirksamkeit und Verträglichkeit eines standardisierten Johanniskraut-Vollextraktes (Ze 117) bei Patienten mit depressiver Symptomatik unterschiedlicher Schweregrade eine Anwendungsbeobachtung. Forsch Komplementärmed 4: 87-93
    • (1997) Forsch Komplementärmed , vol.4 , pp. 87-93
    • Meier, B.1    Liske, E.2    Rosinus, V.3
  • 105
    • 0343742951 scopus 로고
    • Proanthocyanidins from Hypericum perforatum: Effects on isolated pig coronary arteries
    • Melzer, R., Fricke U, Holz, J. (1988) Proanthocyanidins from Hypericum perforatum: Effects on isolated pig coronary arteries. Planta Med. 54: 572-573
    • (1988) Planta Med. , vol.54 , pp. 572-573
    • Melzer, R.1    Fricke, U.2    Holz, J.3
  • 106
    • 0040805180 scopus 로고
    • Therapeutic agents with dramatic antiretroviral activity and little toxicity at effective doses: Aromatic polycyclic diones hypericin and pseudohypericin
    • Meruelo, D., Lavie, G., Lavie, D. (1988) Therapeutic agents with dramatic antiretroviral activity and little toxicity at effective doses: aromatic polycyclic diones hypericin and pseudohypericin. Proc. Natl Acad. Sci. 85: 5230-5234
    • (1988) Proc. Natl Acad. Sci. , vol.85 , pp. 5230-5234
    • Meruelo, D.1    Lavie, G.2    Lavie, D.3
  • 110
    • 0031719029 scopus 로고    scopus 로고
    • Effects of hypericum extract HYP811 in patients with psychovegetative disorders
    • Mueller, B. M. (1998a) Effects of hypericum extract HYP811 in patients with psychovegetative disorders. Adv. Ther. 15: 255-260
    • (1998) Adv. Ther. , vol.15 , pp. 255-260
    • Mueller, B.M.1
  • 111
    • 0031806363 scopus 로고    scopus 로고
    • St John's wort for depressive disorders: Results of an outpatient study with the hypericum preparation HYP811
    • Mueller, B. M. (1998b) St John's wort for depressive disorders: results of an outpatient study with the hypericum preparation HYP811. Adv. Ther. 15: 109-116
    • (1998) Adv. Ther. , vol.15 , pp. 109-116
    • Mueller, B.M.1
  • 112
    • 0030865990 scopus 로고    scopus 로고
    • Effects of hypericum extract (LI 160) in biochemical models of antidepressant activity
    • Müller, W. E., Rolli, M., Schafer, C., Hafner, U. (1997) Effects of hypericum extract (LI 160) in biochemical models of antidepressant activity. Pharmacopsychiatry 30(Suppl): 102-107
    • (1997) Pharmacopsychiatry , vol.30 , Issue.SUPPL. , pp. 102-107
    • Müller, W.E.1    Rolli, M.2    Schafer, C.3    Hafner, U.4
  • 113
    • 0030874985 scopus 로고    scopus 로고
    • Biologically active and other chemical constituents of the herb of Hypericum perforatum L
    • Nahrstedt, A., Butterweck, V. (1997) Biologically active and other chemical constituents of the herb of Hypericum perforatum L. Pharmacopsychiatry 30(Suppl): 129-134
    • (1997) Pharmacopsychiatry , vol.30 , Issue.SUPPL. , pp. 129-134
    • Nahrstedt, A.1    Butterweck, V.2
  • 114
    • 0032824062 scopus 로고    scopus 로고
    • The experimental and clinical pharmacology of St John's wort (Hypericum perforatum L)
    • Nathan, P. J. (1999) The experimental and clinical pharmacology of St John's Wort (Hypericum perforatum L). Molecular Psychiatry 4: 333-338
    • (1999) Molecular Psychiatry , vol.4 , pp. 333-338
    • Nathan, P.J.1
  • 115
    • 0032914931 scopus 로고    scopus 로고
    • Potential metabolic interaction between St John's wort and theophylline
    • Nebel, A., Schneider, B. J., Baker, R. K., Kroll, D. J. (1999) Potential metabolic interaction between St John's wort and theophylline. Ann. Pharmacother. 33: 502
    • (1999) Ann. Pharmacother. , vol.33 , pp. 502
    • Nebel, A.1    Schneider, B.J.2    Baker, R.K.3    Kroll, D.J.4
  • 119
    • 0033917295 scopus 로고    scopus 로고
    • Inhibition of human cytochrome P450 enzymes by constituents of St John's wort, an herbal preparation used in the treatment of depression
    • Obach, R. S. (2000) Inhibition of human cytochrome P450 enzymes by constituents of St John's wort, an herbal preparation used in the treatment of depression. J. Pharmacol. Exp. Ther. 294: 88-95
    • (2000) J. Pharmacol. Exp. Ther. , vol.294 , pp. 88-95
    • Obach, R.S.1
  • 120
    • 0021810731 scopus 로고
    • Separation et identification des acides phenols par chromatographie liquide haute performance et spectroscopie ultra-violette. Application à la pariétaire (Parietaria officinalis L.) et au millepertuis (Hypericum perforatum L.)
    • Ollivier, B., Balansard, G., Maillard, C., Vical, E. (1985) Separation et identification des acides phenols par chromatographie liquide haute performance et spectroscopie ultra-violette. Application à la pariétaire (Parietaria officinalis L.) et au millepertuis (Hypericum perforatum L.). J. Pharm. Belg. 40: 173-177
    • (1985) J. Pharm. Belg. , vol.40 , pp. 173-177
    • Ollivier, B.1    Balansard, G.2    Maillard, C.3    Vical, E.4
  • 121
    • 0033009751 scopus 로고    scopus 로고
    • Inhibition of human sperm motility by specific herbs used in alternative medicine
    • Ondrizek, R. R., Chan, P. J., Patton, W. C., King, A. (1999) Inhibition of human sperm motility by specific herbs used in alternative medicine. J. Assist. Reprod. Genet. 16: 87-91
    • (1999) J. Assist. Reprod. Genet. , vol.16 , pp. 87-91
    • Ondrizek, R.R.1    Chan, P.J.2    Patton, W.C.3    King, A.4
  • 122
    • 0034105176 scopus 로고    scopus 로고
    • Effects of Hypericum perforatum on ethanol intake, and on behavioural despair: A search for the neurochemical systems involved
    • Panocka, I., Perfumi, M., Angeletti, S., Ciccocioppo, R., Massi, M. (2000) Effects of Hypericum perforatum on ethanol intake, and on behavioural despair: a search for the neurochemical systems involved. Pharmacol. Biochem. Behav. 66: 105-111
    • (2000) Pharmacol. Biochem. Behav. , vol.66 , pp. 105-111
    • Panocka, I.1    Perfumi, M.2    Angeletti, S.3    Ciccocioppo, R.4    Massi, M.5
  • 123
    • 0002145226 scopus 로고    scopus 로고
    • Immunosuppressive effects of hypericin on stimulated human leucocytes : Inhibition of the arachidonic acid release, leukotriene b4 and interleukin-1 production and activation of nitric oxide formation
    • Panossian, A. G., Gabrielian, E., Manvelian, V., Vulcic, K., Wagner, H. (1996) Immunosuppressive effects of hypericin on stimulated human leucocytes : inhibition of the arachidonic acid release, leukotriene B4 and interleukin-1 production and activation of nitric oxide formation. Phytomedicine 3: 19-28
    • (1996) Phytomedicine , vol.3 , pp. 19-28
    • Panossian, A.G.1    Gabrielian, E.2    Manvelian, V.3    Vulcic, K.4    Wagner, H.5
  • 125
    • 0033547613 scopus 로고    scopus 로고
    • Hypericum extract versus imipramine or placebo in patients with moderate depression: Randomised multicentre study of treatment for eight weeks
    • Philipp, M., Kohnen, R., Hiller, K. O. (1999) Hypericum extract versus imipramine or placebo in patients with moderate depression: randomised multicentre study of treatment for eight weeks. BMJ 319: 1534-1539
    • (1999) BMJ , vol.319 , pp. 1534-1539
    • Philipp, M.1    Kohnen, R.2    Hiller, K.O.3
  • 128
    • 0032556549 scopus 로고    scopus 로고
    • Hypericum perforatum (St John's wort) in depression: Pest or blessing?
    • Rey, J., Walter, G. (1998) Hypericum perforatum (St John's wort) in depression: pest or blessing? Med. J. Aust. 169: 583-586
    • (1998) Med. J. Aust. , vol.169 , pp. 583-586
    • Rey, J.1    Walter, G.2
  • 129
    • 0032871950 scopus 로고    scopus 로고
    • Attenuation of alcohol intake by extract of Hypericum perforatum (St John's wort) in two different strains of alcohol-preferring rats
    • Rezvani, A. H., Overstreet, D. H., Yang, Y., Clarke, E. (1999) Attenuation of alcohol intake by extract of Hypericum perforatum (St John's wort) in two different strains of alcohol-preferring rats. Alcohol Alcohol. 34: 699-705
    • (1999) Alcohol Alcohol. , vol.34 , pp. 699-705
    • Rezvani, A.H.1    Overstreet, D.H.2    Yang, Y.3    Clarke, E.4
  • 131
    • 0034639638 scopus 로고    scopus 로고
    • Acute heart transplant rejection due to Saint John's wort
    • Ruschitzka, F., Meier, P. J., Turina, M., Luscher, T. F., Noll, G. (2000) Acute heart transplant rejection due to Saint John's wort. Lancet 355: 548-549
    • (2000) Lancet , vol.355 , pp. 548-549
    • Ruschitzka, F.1    Meier, P.J.2    Turina, M.3    Luscher, T.F.4    Noll, G.5
  • 132
    • 0031780097 scopus 로고    scopus 로고
    • Pharmacodynamic effects of two different hypericum extracts in healthy volunteers measured by quantitative EEG
    • Schellenberg, R., Sauer, S., Dimpfel, W. (1998) Pharmacodynamic effects of two different hypericum extracts in healthy volunteers measured by quantitative EEG. Pharmacopsychiatry 31(Suppl): 44-53
    • (1998) Pharmacopsychiatry , vol.31 , Issue.SUPPL. , pp. 44-53
    • Schellenberg, R.1    Sauer, S.2    Dimpfel, W.3
  • 133
    • 0032771917 scopus 로고    scopus 로고
    • Hypericin levels in human serum and interstitial skin blister fluid after oral single-dose and steady-state administration of hypericum perforatum extract (St John's wort)
    • Schempp, C., Winghofer, B., Langheinrich, M., Schopt, E., Simon, J. C (1999a) Hypericin levels in human serum and interstitial skin blister fluid after oral single-dose and steady-state administration of Hypericum perforatum extract (St John's wort). Skin Pharmacol. Appl. Skin Physiol. 12: 299-304
    • (1999) Skin Pharmacol. Appl. Skin Physiol. , vol.12 , pp. 299-304
    • Schempp, C.1    Winghofer, B.2    Langheinrich, M.3    Schopt, E.4    Simon, J.C.5
  • 134
    • 0344654719 scopus 로고    scopus 로고
    • Antibacterial activity of hyperforin from St John's wort, against multiresistant Staphylococcus aureus and gram-positive bacteria
    • Schempp, C., Pelz, K., Wittmer, A., Schopf, E., Simon, J. C. (1999b) Antibacterial activity of hyperforin from St John's wort, against multiresistant Staphylococcus aureus and gram-positive bacteria. Lancet 353: 2129
    • (1999) Lancet , vol.353 , pp. 2129
    • Schempp, C.1    Pelz, K.2    Wittmer, A.3    Schopf, E.4    Simon, J.C.5
  • 135
    • 0034103796 scopus 로고    scopus 로고
    • Topical application of St John's wort (Hypericum perforatum l.) and of its metabolite hyperforin inhibits the allostimulatory capacity of epidermal cells
    • Schempp, C. M., Winghofer, B., Ludtke, R., Simon-Haarhuis, B., Schopf, E., Simon, J. C. (2000a) Topical application of St John's wort (Hypericum perforatum L.) and of its metabolite hyperforin inhibits the allostimulatory capacity of epidermal cells. Jr. J. Dermatol. 142: 979-984
    • (2000) Jr. J. Dermatol. , vol.142 , pp. 979-984
    • Schempp, C.M.1    Winghofer, B.2    Ludtke, R.3    Simon-Haarhuis, B.4    Schopf, E.5    Simon, J.C.6
  • 136
    • 0342424206 scopus 로고    scopus 로고
    • Effect of topical application of Hypericum perforatum extract (St John's wort) on skin sensitivity to solar simulated radiation
    • Schempp, C. M., Ludtke, R., Winghofer, B., Simon, J. C. (2000b) Effect of topical application of Hypericum perforatum extract (St John's wort) on skin sensitivity to solar simulated radiation. Photodermatol. Photoimmunol. Photomed. 16: 125-128
    • (2000) Photodermatol. Photoimmunol. Photomed. , vol.16 , pp. 125-128
    • Schempp, C.M.1    Ludtke, R.2    Winghofer, B.3    Simon, J.C.4
  • 138
    • 0032415734 scopus 로고    scopus 로고
    • St John's wort and hypomania
    • Schneck, C. (1998) St John's wort and hypomania. J. Clin. Psychiatry 59: 689
    • (1998) J. Clin. Psychiatry , vol.59 , pp. 689
    • Schneck, C.1
  • 139
    • 0034008572 scopus 로고    scopus 로고
    • Equivalence of st john's wort extract (Ze 117) and fluoxetine: A randomized, controlled study mild-moderate depression
    • Schrader, E. (2000) Equivalence of St John's wort extract (Ze 117) and fluoxetine: a randomized, controlled study mild-moderate depression. Int. J. Clin. Psychopharmacol. 15: 61-68
    • (2000) Int. J. Clin. Psychopharmacol. , vol.15 , pp. 61-68
    • Schrader, E.1
  • 140
    • 0031966728 scopus 로고    scopus 로고
    • Hypericum treatment of mild-moderate depression in a placebo-controlled study. A prospective, double-blind, randomized, placebo-controlled, multicentre study
    • Schrader, E., Meier, B., Brattström, A. (1998) Hypericum treatment of mild-moderate depression in a placebo-controlled study. A prospective, double-blind, randomized, placebo-controlled, multicentre study. Human Psychopharmacol. 13: 163-169
    • (1998) Human Psychopharmacol. , vol.13 , pp. 163-169
    • Schrader, E.1    Meier, B.2    Brattström, A.3
  • 142
    • 0031711433 scopus 로고    scopus 로고
    • Antidepressant-like effect of Hypericum perforatum (St John's wort) on the sleep polysomnogram
    • Sharpley, A. L., McGavin, C. L., Whale, R., Cowen, P. J. (1998) Antidepressant-like effect of Hypericum perforatum (St John's wort) on the sleep polysomnogram. Psychopharmacology 139: 286-287
    • (1998) Psychopharmacology , vol.139 , pp. 286-287
    • Sharpley, A.L.1    McGavin, C.L.2    Whale, R.3    Cowen, P.J.4
  • 143
    • 0019757777 scopus 로고
    • Extracts from a group of medicinal plants enhancing the uterine tonus
    • Shiplochliev, T. (1981) Extracts from a group of medicinal plants enhancing the uterine tonus. Vet Med Nauki 18: 94-98
    • (1981) Vet Med Nauki , vol.18 , pp. 94-98
    • Shiplochliev, T.1
  • 145
    • 0027427260 scopus 로고
    • Zur frage der phototoxizität von hypericum
    • Siegers, C., Biel, S., Wilhelm, K-P. (1993) Zur Frage der Phototoxizität von Hypericum. Nervenheilkunde 12: 320-322
    • (1993) Nervenheilkunde , vol.12 , pp. 320-322
    • Siegers, C.1    Biel, S.2    Wilhelm, K.-P.3
  • 148
    • 0027946782 scopus 로고
    • Pharmacokinetics of hypericin and pseudohypericin after oral intake of the Hypericum perforatum extract LI 160 in healthy volunteers
    • Staffeldt, B., Kerb, R., Brockmoller, J., Ploch, M., Roots, I. (1994) Pharmacokinetics of hypericin and pseudohypericin after oral intake of the Hypericum perforatum extract LI 160 in healthy volunteers. J. Geriatr. Psychiatry Neurol. 7: S47-53
    • (1994) J. Geriatr. Psychiatry Neurol. , vol.7
    • Staffeldt, B.1    Kerb, R.2    Brockmoller, J.3    Ploch, M.4    Roots, I.5
  • 149
    • 0040081421 scopus 로고
    • Successful long-term treatment over 40 months of HIV-patients with intravenous hypericin
    • Steinbeck-Klose, A., Wernet, P. (1993) Successful long-term treatment over 40 months of HIV-patients with intravenous hypericin [abstract]. International Conference on AIDS 9: 470
    • (1993) International Conference on AIDS , vol.9 , pp. 470
    • Steinbeck-Klose, A.1    Wernet, P.2
  • 150
    • 0032964314 scopus 로고    scopus 로고
    • Safety of hypericum in patients with depression. A comparison with conventional antidepressants
    • Stevinson, C., Ernst E. (1999) Safety of hypericum in patients with depression. A comparison with conventional antidepressants. CNS Drugs 11: 125-132
    • (1999) CNS Drugs , vol.11 , pp. 125-132
    • Stevinson, C.1    Ernst, E.2
  • 151
    • 0034053611 scopus 로고    scopus 로고
    • A pilot study of hypericum perforatum, for the treatment of premenstrual syndrome
    • Stevinson, C., Ernst, E. (2000) A pilot study of Hypericum perforatum, for the treatment of premenstrual syndrome. Br. J. Obstet. Gynaecol. 107: 870-876
    • (2000) Br. J. Obstet. Gynaecol. , vol.107 , pp. 870-876
    • Stevinson, C.1    Ernst, E.2
  • 152
    • 0000409896 scopus 로고    scopus 로고
    • Hypericum for fatigue a pilot study
    • Stevinson, C., Dixon, M., Ernst, E. (1998) Hypericum for fatigue a pilot study. Phytomedicine 5: 443-447
    • (1998) Phytomedicine , vol.5 , pp. 443-447
    • Stevinson, C.1    Dixon, M.2    Ernst, E.3
  • 155
    • 0024847267 scopus 로고
    • Hypericin and pseudohypericin specifically inhibit protein kinase C: Possible relation to their antiretroviral activity
    • Takahashi, I., Nakanishi, S., Kobayashi, E., Nakano, H., Suzuki, K., Tamaoki, T. (1989) Hypericin and pseudohypericin specifically inhibit protein kinase C: possible relation to their antiretroviral activity. Biochem. Biophys. Res. Comm. 165: 1207-1212
    • (1989) Biochem. Biophys. Res. Comm. , vol.165 , pp. 1207-1212
    • Takahashi, I.1    Nakanishi, S.2    Kobayashi, E.3    Nakano, H.4    Suzuki, K.5    Tamaoki, T.6
  • 156
    • 0033855762 scopus 로고    scopus 로고
    • An open-label trial of St John's wort (Hypericum perforatum) in obsessive-compulsive disorder
    • Taylor, L. H., Kobak, K. A. (2000) An open-label trial of St John's wort (Hypericum perforatum) in obsessive-compulsive disorder. J. Clin. Psychiatry 61: 575-578
    • (2000) J. Clin. Psychiatry , vol.61 , pp. 575-578
    • Taylor, L.H.1    Kobak, K.A.2
  • 157
    • 0027994755 scopus 로고
    • Inhibition of MAO and COMT by Hypericum extracts and hypericin
    • Thiede, H. M., Walper, A. (1994) Inhibition of MAO and COMT by Hypericum extracts and hypericin. J. Ger. Psychiatry Neurol. 7: S54-56
    • (1994) J. Ger. Psychiatry Neurol. , vol.7
    • Thiede, H.M.1    Walper, A.2
  • 161
    • 0000699327 scopus 로고
    • Quantitative determination of biologically active constituents in medicinal plant crude extracts by thin-layer chromatography-densitometry
    • Vanhaelen, M., Vanhaelen-Fastre, R. (1983) Quantitative determination of biologically active constituents in medicinal plant crude extracts by thin-layer chromatography-densitometry. J. Chromatogr. 281: 263-271
    • (1983) J. Chromatogr. , vol.281 , pp. 263-271
    • Vanhaelen, M.1    Vanhaelen-Fastre, R.2
  • 162
    • 0032997269 scopus 로고    scopus 로고
    • Furohyperforin, a prenylated phloroglucinol from st. John's wort (Hypericum perforatum)
    • Verotta, L., Appendino, G., Belloro, E., Jakupovic, J., Bombardelli, E. (1999) Furohyperforin, a prenylated phloroglucinol from st. John's wort (Hypericum perforatum). J. Nat. Prod. 62: 770-772
    • (1999) J. Nat. Prod. , vol.62 , pp. 770-772
    • Verotta, L.1    Appendino, G.2    Belloro, E.3    Jakupovic, J.4    Bombardelli, E.5
  • 163
    • 0034062571 scopus 로고    scopus 로고
    • Hyperforin analogues from St John's wort (Hypericum perforatum)
    • Verotta, L., Appendino, G., Jakupovic, J., Bombardelli, E. (2000) Hyperforin analogues from St John's wort (Hypericum perforatum). J. Nat. Prod. 63: 412-415
    • (2000) J. Nat. Prod. , vol.63 , pp. 412-415
    • Verotta, L.1    Appendino, G.2    Jakupovic, J.3    Bombardelli, E.4
  • 164
    • 0032987555 scopus 로고    scopus 로고
    • Hypericum perforatum extracts as potential antidepressants
    • Vitiello, B. (1999) Hypericum perforatum extracts as potential antidepressants. J. Pharm. Pharmacol. 51: 513-517
    • (1999) J. Pharm. Pharmacol. , vol.51 , pp. 513-517
    • Vitiello, B.1
  • 165
    • 0033612827 scopus 로고    scopus 로고
    • Antibacterial activity of hyperforin from St John's wort
    • Voss, A., Verweij, P. E. (1999) Antibacterial activity of hyperforin from St John's wort. Lancet 354: 777
    • (1999) Lancet , vol.354 , pp. 777
    • Voss, A.1    Verweij, P.E.2
  • 166
    • 0028234190 scopus 로고
    • The antiviral agent hypericin has in vitro activity against HSV-1 through non-specific association with viral and cellular membranes
    • Weber, N. D., Murray, B. K., North, J. A., Wood, S. G. (1994) The antiviral agent hypericin has in vitro activity against HSV-1 through non-specific association with viral and cellular membranes. Antiviral Chemistry & Chemotherapy 5: 83-90
    • (1994) Antiviral Chemistry & Chemotherapy , vol.5 , pp. 83-90
    • Weber, N.D.1    Murray, B.K.2    North, J.A.3    Wood, S.G.4
  • 167
    • 0032939649 scopus 로고    scopus 로고
    • Hypericum in seasonal affective disorder (SAD)
    • Wheatley, D. (1999) Hypericum in seasonal affective disorder (SAD). Curr. Med. Res. Opin. 15: 33-37
    • (1999) Curr. Med. Res. Opin. , vol.15 , pp. 33-37
    • Wheatley, D.1
  • 168
    • 0034596545 scopus 로고    scopus 로고
    • Comparison of St John's wort and imipramine for treating depression : Randomised controlled trial
    • Woelk, H. (2000) Comparison of St John's wort and imipramine for treating depression : randomised controlled trial. BMJ 321: 536-539
    • (2000) BMJ , vol.321 , pp. 536-539
    • Woelk, H.1
  • 169
    • 0027973836 scopus 로고
    • Benefits and risks of the hypericum extract LI 160. Drug monitoring study with 3250 patients
    • Woelk, H., Burkard, G., Grunwald, J. (1994) Benefits and risks of the hypericum extract LI 160. Drug monitoring study with 3250 patients. J. Geriatr. Psychiatry Neurol. 7(Suppl. 1): 34-38
    • (1994) J. Geriatr. Psychiatry Neurol. , vol.7 , Issue.1 SUPPL. , pp. 34-38
    • Woelk, H.1    Burkard, G.2    Grunwald, J.3
  • 170
    • 0034131070 scopus 로고    scopus 로고
    • Inhibition of synaptosomal uptake of 3H-L-glutamate and 3H-GABA by hyperforin, a major constituent of st john's wort: The role of amiloride sensitive sodium conductive pathways
    • Wonnemann, M., Singer, A., Muller, W. E. (2000) Inhibition of synaptosomal uptake of 3H-L-glutamate and 3H-GABA by hyperforin, a major constituent of St John's wort: the role of amiloride sensitive sodium conductive pathways. Neuropsychopharmacology 23: 188-197
    • (2000) Neuropsychopharmacology , vol.23 , pp. 188-197
    • Wonnemann, M.1    Singer, A.2    Muller, W.E.3
  • 172
    • 0033624787 scopus 로고    scopus 로고
    • Effect of the Hypericum perforatum extract on serotonin turnover in the mouse brain
    • Yu, P. H. (2000) Effect of the Hypericum perforatum extract on serotonin turnover in the mouse brain. Pharmacopsychiatry 33: 60-65
    • (2000) Pharmacopsychiatry , vol.33 , pp. 60-65
    • Yu, P.H.1
  • 173
    • 0034639564 scopus 로고    scopus 로고
    • Safety of St John's wort (Hypericum perforatum)
    • Yue, Q-Y., Bergquist, C., Gerden, B. (2000) Safety of St John's wort (Hypericum perforatum). Lancet 355: 576-577
    • (2000) Lancet , vol.355 , pp. 576-577
    • Yue, Q.-Y.1    Bergquist, C.2    Gerden, B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.