St. John's Wort for depression: A meta-analysis of well-defined clinical trials

Journal of Nervous and Mental Disease

Volumn 187, Issue 9, 1999, Pages 532-538

  Kim, Hannah L ^a   Streltzer, Jon ^a   Goebert, Deborah ^a  

^a UNIVERSITY OF HAWAII   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TRICYCLIC ANTIDEPRESSANT AGENT;

ALTERNATIVE MEDICINE; ARTICLE; CLINICAL TRIAL; DEPRESSION; DRUG EFFICACY; DRUG RESPONSE; FATIGUE; GASTROINTESTINAL SYMPTOM; HEADACHE; HUMAN; HYPERICUM PERFORATUM; META ANALYSIS; VERTIGO; XEROSTOMIA;

ADULT; ANTIDEPRESSIVE AGENTS, TRICYCLIC; CONTROLLED CLINICAL TRIALS; DEPRESSIVE DISORDER; DOUBLE-BLIND METHOD; DRUG ADMINISTRATION SCHEDULE; HUMANS; PATIENT DROPOUTS; PHYTOTHERAPY; PLACEBOS; PSYCHIATRIC STATUS RATING SCALES; RESEARCH DESIGN; THEALES; TREATMENT OUTCOME;

EID: 0032881183     PISSN: 00223018     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005053-199909000-00002     Document Type: Article

References (31)

1. Bergmann R Nubner J, Demling J (1993) Behandlung leichter bis Mittelschwerer Depressionen. Therapiewoche Neurologie/Psychiatrie 7:235-240.
2. Cott J (1995) NCDEU update: Natural product formulations available in Europe for psychotropic indications. Psychopharmacol Bull 31:745-751.
3. Dean J, Dean A, Burton A, Dicker R (1995) Epi Info Ver 6.0. Atlanta, GA: Centers for Disease Control.
4. Ditzler K, Gessner B, Schatton WFH, Willems M (1994) Clinical trial on Neurapas versus placebo in patients with mild to moderate depressive Symptoms: a placebo-controlled randomizeddouble-blind study. Complementary Therapies in Medicine 2:5-13.
5. Eisenberg DM, Davis RB, Ettner SL, Appel S, Wilkey S, Van Rompay M, Kessler RC (1998) Trends in alternative medicine use in the United States, 1990-1997: Results of a follow-up national survey. JAMA 280:1569-1575.
6. Giron M, Majon-Arce P, Puerto-Barber J, Puerto-Barber J, Sanchez-Garcia E, Gomez-Beneyto M (1998) Clinical interview skills and identification of emotional disorders in primary care. Am J Psychiatry 155:530-535.
7. Hamilton M (1967) Development of a rating scale for primary depressive illness. Br J Soc Clin Psychol 6:278-296.
8. Hansgen KD, Vesper J, Ploch M (1994) Multicenter double-blind study examining the antidepressant effectiveness of the hypericum extract LI 160. J Geriatr Psychiatry Neurol 7(suppl 1); S15-S18.
9. Harrer G, Hubner WD, Podzuweit H (1994) Effectiveness and tolerance of the Hypericum extract LI 160 compared to Maprotiline: A multicenter double-blind study. J Geriatr Psychiatry Neurol 7(suppl 1):S24-S28.
10. Harrer G, Schulz V (1994) Clinical investigation of the antidepressant effectiveness of Hypericum. J Geriatr Psychiatry Neurol 7(suppl 1):S6-S8.
11. Herbert TB, Cohen S (1993) Stress and immunity in humans: A meta-analytic review. Psychosom Med 55:364-379.
12. Janicak PG, Davis JM, Preskorn SH, Ayd FJ (1997) Treatment with antidepressant. In PG Janicak (Ed), Principles and practice of psychopharmacotherapy (2nd ed, pp 2433-350). Baltimore: Williams & Wilkins.
13. Jewel D (1997) Flower power: The herb known as St. John's Wort is helping thousands overcome depression. People Weekly 48(18):85.
14. Kessel JB, Simpson GM (1995) Biologic therapies: Tricyclic and tetracyclic drugs. In HI Kaplan, BJ Sadock (Eds), Comprehensive textbook of psychiatry (6th ed, Vol 2, pp 2110-2112). Baltimore: Williams & Wilkins.
15. Klemm Analysis Group (1997) Epimeta Ver 1.1 Atlanta, GA: Centers for Disease Control.
16. Kunze H, Priebe S (1998) Assessing the quality of psychiatric hospital care: A German approach. Psychiatr Serv 49:794-796.
17. Linde K, Ramirez G, Mulrow CD, Pauls A, Weidenhammar W, Melchart D (1996) St. John's wort for depression: An overview and meta-analysis of randomized clinical trials. Br. Med J 313: 353-358.
18. Marder SR (1995) Psychiatric rating scales: Depression scales. In HI Kaplan, BJ Sadock (Eds), Comprehensive textbook of psychiatry (6th ed, Vol 1, p 622). Baltimore: Williams & Wilkins.
19. Miller S (1997) Depression: A natural mood booster. Newsweek 129(18):74.
20. Miyawaki E (1998) Medicine: Listening to St. John's Wort. Atlantic Monthly 281(5):40.
21. Muller JL, Clauson KA (1997) Pharmaceutical considerations of common herbal medicine. Am J Man Care 3:1753-1770.
22. Nash JM (1997) Health: Nature's Prozac. Time 150(12):80.
23. Nielsen AC III, Williams TA (1980) Depression in ambulatory medical patients. Arch Gen Psychiatry 37:999-1004.
24. Orwin RG, Cordray DS (1985) Effects of deficient reporting on meta-analysis: A conceptual framework and reanalysis. Psychol Bull 97:134-147.
25. Rosenthal R (1991) Meta-analysis: A Review. Psychosom Med 53: 247-271.
26. Schatzberg AF, Cole JO, DeBattista C (1997) Antidepressants: Tricyclic antidepressants and related compounds. In Manual of Clinical Psychopharmacology (3rd ed, pp 41-43). Washington, DC: American Psychiatric Press, Inc.
27. Steger W (1985) Depressive Verstimmungen. Z Allgemeinmed 61: 914-918.
28. Volz HP (1997) Controlled clinical trials of Hypericum extracts in depressed patients: An overview. Pharmacopsychiatry 30:S72-S76.
29. Vorbach EU, Hubner WD, Arnoldt KH (1994) Effectiveness and tolerance of the Hypericum extract LI 160 in comparison with Imipramine: Randomized double-blind study with 135 outpatients. J Geriatr Psychiatry Neurol 7(suppl 1):S19-S23.
30. Wheatley D (1997) LI 160, an extract of St. John's Wort, versus Amitriptyline in mildly to moderately depressed outpatients: A controlled 6-week clinical trial. Pharmacopsychiatry 30:S77-S80.
31. Witte VB, Harrer G, Kaptan T, Podzuweit H, Schmidt V (1995) Treatment of depressive symptoms with a high concentration hypericum preparation: A multicenter placebo-controlled double-blind study. Fortschr Med 113:404-408.