Molecular genetics and the epidemiology of bipolar disorder

Annals of Medicine

Volumn 33, Issue 4, 2001, Pages 242-247

  Blackwood, D ^a   Muir, W ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

Age at Onset; Anticipation; Bipolar disorder; Chromosome 1; Epidemiology; Genetics; Linkage; Phenotype

Indexed keywords

ANTICIPATION; CHROMOSOMAL LOCALIZATION; CHROMOSOME 1; DEMOGRAPHY; EPIDEMIOLOGICAL DATA; GENETIC LINKAGE; GENETIC VARIABILITY; MANIC DEPRESSIVE PSYCHOSIS; MOLECULAR GENETICS; MUTATION; PHENOTYPE; PRIORITY JOURNAL; REVIEW; RISK FACTOR; SOCIAL SUPPORT;

EID: 0034992238     PISSN: 07853890     EISSN: None     Source Type: Journal    
DOI: 10.3109/07853890108998752     Document Type: Review

References (60)

1. A family study of schizoaffective, bipolar I, bipolar II, unipolar, and normal control probands
2. Searching high and low: A review of the genetics of bipolar disorder
3. Molecular genetics in psychiatric epidemiology: The promise and challenge
4. Genetic basis of schizophrenia
5. Genetic linkage and complex diseases, with special reference to psychiatric disorders
6. Linkage disequilibrium mapping of complex disease: Fantasy or reality?
7. Human morbid genetics revisited: Relevance of epigenetics
8. Searching for genetic determinants in the new millennium
9. Assessment of lineality in bipolar I linkage studies
10. A locus for bipolar affective disorder on chromosome 4p
11. Genome-wide search for linkage of bipolar affective disorders in a very large pedigree derived from a homogeneous population in quebec points to a locus of major effect on chromosome 12q23-q24
12. Significant linkage between bipolar affective disorder and chromosome 12q24
13. Familial cosegregation of major affective disorder and Darier's disease (keratosis follicularis)
14. Genetic mapping using haplotype, association and linkage methods suggests a locus for severe bipolar disorder (BPI) at 18q22-q23
15. A possible vulnerability locus for bipolar affective disorder on chromosome 21q22.3
16. Evidence of a predisposing locus to bipolar disorder on Xq24-q27.1 in an extended Finnish pedigree
17. Nonsyndromic hearing impairment: Unparalleled heterogeneity
18. Molecular genetics of human retinal disease
19. The structure of psychosis: Latent class analysis of probands from the Roscommon Family Study
20. Bipolar disorder and panic disorder in families: An analysis of chromosome 18 data
21. Genetic epidemiology of major depression: Review and meta-analysis
22. Linkage and associated studies of schizophrenia
23. Susceptibility loci for bipolar disorder: Overlap with inherited vulnerability to schizophrenia
24. Do schizophrenia and affective disorder share susceptibility genes?
25. Continuity and discontinuity of affective disorders and schizophrenia. Results of a controlled family study
26. Association within a family of a balanced autosomal translocation with major mental illness
27. Genetic dissection of complex traits: Guidelines for interpreting and reporting linkage results
28. Genome-wide scan for schizophrenia in the Finnish population: Evidence for a locus on chromosome 7q22
29. A genomewide screen for schizophrenia genes in an isolated Finnish subpopulation, suggesting multiple susceptibility loci
30. Linkage analysis of fifty-seven microsatellite loci to bipolar disorder
31. A follow-up report of a genome search for affective disorder predisposition loci in the Old Order Amish
32. A high-density genome scan detects evidence for a bipolar-disorder susceptibility locus on 13q32 and other potential loci on 1q32 and 18p11.2
33. Disruption of two novel genes by a translocation co-segregating with schizophrenia
34. Angiotensinogen and angiotensin converting enzyme gene polymorphisms and the risk of bipolar affective disorder in humans
35. Sex differences in rates of depression: Crossnational perspectives
36. Sex and depression in the National Comorbidity Survey. I: Lifetime prevalence, chronicity and recurrence
37. Birth-cohort trends in rates of major depressive disorder among relatives of patients with affective disorder
38. Birth cohort trends in major depression: Increasing rates and earlier onset in New Zealand
39. Birthcohort changes in manic and depressive disorders in relatives of bipolar and schizoaffective patients
40. Age, period and cohort effects on the risk of major depression: Results from five United States communities
41. Trinucleotide repeats in neurogenetic disorders
42. Genetic anticipation and imprinting in bipolar I illness
43. Anticipation in Swedish families with bipolar affective disorder
44. Anticipation and imprinting in Japanese familial mood disorders
45. Expanded trinucleotide CAG repeats in families with bipolar affective disorder
46. Anticipation in bipolar affective disorder
47. Anticipation in schizophrenia and bipolar disorder controlling for an information bias
48. Genetic survival analysis of age-ofonset of bipolar disorder, evidence for anticipation and a year-of-birth effect
49. No evidence to support the association of the potassium channel gene hSKCa3 CAG repeat with schizophrenia or bipolar disorder in the Irish population
50. Analysis of thirteen trinucleotide repeat loci as candidate genes for schizophrenia and bipolar affective disorder
51. Psychosis and genes with trinucleotide repeat polymorphism
52. Direct detection of novel expanded trinucleotide repeats in the human genome
53. Detection of expanded CAG repeats in bipolar affective disorder using the repeat expansion detection (RED) method
54. Two commonly expanded CAG/CTG repeat loci: Involvement in affective disorders?
55. Confirmation of association between expanded CAG/CTG repeats and both schizophrenia and bipolar disorder
56. Analysis of CAG/CTG repeat size in Chinese subjects with schizophrenia and bipolar affective disorder using the repeat expansion detection method
57. CAG repeat sequences in bipolar affective disorder: No evidence for association in a French population
58. A preliminary study on early onset schizophrenia and bipolar disorder: Large polyglutamine expansions are not involved
59. Expanded CAG/CTG repeats in bipolar disorder: No correlation with phenotypic measures of illness severity
60. COMT and DRD3 polymorphisms, environmental exposures, and personality traits related to common mental disorders