Analysis of CAG/CTG repeat size in Chinese subjects with schizophrenia and bipolar affective disorder using the repeat expansion detection method

Biological Psychiatry

Volumn 44, Issue 11, 1998, Pages 1160-1165

  Li, Tao ^a   Vallada, Homero P ^a   Liu, Xiehe ^b   Xie, Tao ^b   Tang, Xiangdong ^b   Zhao, Jinghua ^a   O'Donovan, Michael C ^c   Murray, Robin M ^a   Sham, Pak C ^a   Collier, David A ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b SICHUAN UNIVERSITY   (China)

^c CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

Allelic association; Anticipation; Expansion; Psychosis; Repeat expansion detection; Triplet repeat

Indexed keywords

ADOLESCENT; ADULT; ALLELE; ARTICLE; FEMALE; GENETIC ANALYSIS; GENETIC SUSCEPTIBILITY; HUMAN; MAJOR CLINICAL STUDY; MALE; MANIC DEPRESSIVE PSYCHOSIS; NUCLEOTIDE REPEAT; PRIORITY JOURNAL; SCHIZOPHRENIA; TRINUCLEOTIDE REPEAT;

ADOLESCENT; ADULT; ALLELES; BIPOLAR DISORDER; CHINA; FEMALE; HUMANS; MALE; SCHIZOPHRENIA; SEX FACTORS; TRINUCLEOTIDE REPEAT EXPANSION;

EID: 0032403843     PISSN: 00063223     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3223(97)00492-7     Document Type: Article

References (31)

1. Asherson P., Walsh C., Williams J., Sergeant M., Taylor C., Clements A., et al. Imprinting and anticipation Are they relevant to genetic studies of schizophrenia? Br J Psychiatry. 164:1994;619-624.
2. Bassett A.S., Honer W.G. Evidence for anticipation in schizophrenia. Am J Hum Genet. 54:1994;864-870.
3. Cardno A.G., Murphy K.C., Jones L.A., Guy C., Asherson P., Azevedo M.H.P., et al. Expanded CAG/CTG repeats in schizophrenia A study of clinical correlates . Br J Psychiatry. 169:1996;766-771.
4. Gastier J.M., Brody T., Pulido J.C., Businga T., Sunden S., Hu X., et al. Development of a screening set for new (CAG/CTG)n dynamic mutations. Genomics. 32:1995;74-85.
5. Haaf T., Sirugo G., Kidd K.K., Ward D.C. Chromosomal localisation of long trinucleotide repeats in the human genome by fluorescence in situ hybridisation. Nat Genet. 12:1996;183-185.
6. Hofferbert S., Schanen N.C., Chehab F., Franke U. Trinucleotide repeats in the human genome Size distributions for all possible triplets and detection of expanded disease alleles in a group of Huntington disease individuals by the repeat expansion detection method . Hum Mol Genet. 6:1997;77-83.
7. Lindblad K., Nylander P.-O., De Bryn A., Sourey A., Zander C., Engstrom C., et al. Detection of expanded CAG repeats in bipolar affective disorder using the RED method. Neurobiol Dis. 2:1995;55-62.
8. McInnis M.G., McMahon M.J., Chase G.A., Simpson S.G., Ross C.A., DePaulo J.R. Jr. Anticipation in bipolar affective disorder. Am J Hum Genet. 53:1993;385-390.
9. Morris A.G., Gaitonde E., McKenna P., Mollon J.D., Hunt D.M. CAG repeat expansions and schizophrenia Association with disease in females and with early age-at-onset . Hum Mol Genet. 4:1995;1957-1961.
10. Mott F.W. A lecture on heredity and insanity. Lancet. i:1911;1251-1259.
11. Nylander P.-O., Engstrom C., Chotai J., Walstrom J., Adolfson R. Anticipation in Swedish families with bipolar affective disorder. J Med Genet. 31:1994;686-689.
12. O'Donovan M.C., Owen M. Dynamic mutations and psychiatric genetics. Psychol Med. 26:1996;1-6.
13. O'Donovan M.C., Guy C. Bias in the genomic distribution of CAG and CTG trinucleotide repeats. Am J Med Genet. 74:1997;62-64.
14. O'Donovan M.C., Guy C., Craddock N., Murphy K.C., Cardno A.G., Jones L.A., et al. Expanded CAG repeats in schizophrenia and bipolar disorder. Nat Genet. 10:1995;380-381.
15. O'Donovan M.C., Guy C., Craddock N., Bowen T., McKeon P., Macedo A., et al. Confirmation of association between expanded CAG/CTG repeats and both schizophrenia and bipolar disorder. Psychol Med. 26:1996;1145-1153.
16. O'Donovan M.C., Craddock N., Guy C., McGuffin P., Owen M.J. Involvement of CAG/CTG repeats in common diseases. Lancet. 348:1996;1737-1738.
17. O'Neil J., Bryjolfsson J., Curtis D., Rifkin L., Maloney E., Murphy P., et al. Testing the hypothesis of genomic imprinting and anticipation in bipolar and related unipolar affective disorder. Psychiatr Genet. 3:1993;151.
18. Paterson A.D., Kennedy J.L., Petronis A. Evidence for genetic anticipation in non-Mendelian diseases. Am J Hum Genet. 59:1996;264-268.
19. Penrose L.S. The problem of anticipation in pedigrees of dystrophia myotonica. Ann Eugenics (Lond). 14:1948;125-132.
20. Penrose L.S. Critical survey of schizophrenia genetics. Howells J.G. Modern Perspectives in World Psychiatry. 1991;3-19 Oliver and Boyd, Edinburgh.
21. Petronis A., Kennedy J.L. Unstable genes - unstable mind? Am J Psychiatry. 152:1995;164-172.
22. Petronis A., Sherrington R., Kennedy J.L. Regression to the mean does not exclude anticipation and unstable DNA disease. Am J Hum Genet. 55:1994;589-592.
23. Petronis A., Bassett A.S., Honer W.G., Vincent J.B., Tatuch Y., Sasaki T., et al. Search for unstable DNA in schizophrenia families with evidence for genetic anticipation. Am J Hum Genet. 59:1996;905-911.
24. Schalling M., Hudson T.J., Buetow K.H., Houseman D.E. Direct detection of novel expanded trinucleotide repeats in the human genome. Nat Genet. 4:1993;135-139.
25. Schalling M., Nylander P.O., Zander C., Engstrom C., Adolfsson R., Lindblad K. CAG repeat expansions co-segregate with bipolar affective disorder. Am J Hum Genet. 59:1996;A235.
26. Sharma T., Brynjolfsson J., Butler R., Murphy P., Petursson H., Read T., et al. Anticipation in schizophrenia. Schizophr Res. 11:1994;141.
27. Sirugo G., Deinard A.S., Wilson B., Kidd J.R., Kidd K.K. Survey of maximum CAG/CTG repeat lengths in humans and non-human primates Total genome scan using the repeat expansion detection method . Hum Mol Genet. 6:1997;403-408.
28. Sirugo G., Haaf T., Parnas J., Matthysse S., Levy D., Holzman P., et al. A (CTG)n expansion detected by RED in a schizophrenia kindred maps to 18q21 by FISH with a CAG/CTG polymer. Am J Human Genet. 57:1995;A36.
29. Stallings R.L. Distribution of trinucleotide microsatellites in schizophrenia and bipolar affective disorder. Mol Psychiatry. 21:1994;116-121.
30. Sutherland G.R., Richards R.I. Dynamic mutations A new class of mutations causing human disease . Cell. 70:1992;709-712.
31. Vincent J.B., Klempan T., Parikh S.S., Sasaki T., Meltzer H.Y., Sirugo G., et al. Frequency analysis of large CAG/CTG trinucleotide repeats in schizophrenia and bipolar affective disorder. Mol Psychiatry. 1:1996;141-148.