CAG repeat sequences in bipolar affective disorder: No evidence for association in a French population

American Journal of Medical Genetics - Neuropsychiatric Genetics

Volumn 81, Issue 4, 1998, Pages 338-341

  Zander, Cecilia ^a   Schürhoff, Franck ^b   Laurent, Claudine ^b   Chavand, Olivier ^b   Bellivier, Frank ^b   Samolyk, Danièle ^b   Leboyer, Marion ^b   Allilaire, Jean François ^b   Cann, Howard ^a   Néri, Christian ^a   Mallet, Jacques ^b  

^a FONDATION JEAN DAUSSET CEPH   (France)

^b PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

Author keywords

Anticipation; Bipolar affective disorder; Genetics; Polyglutamine; Trinucleotide repeat expansion

Indexed keywords

ADENINE; CYTOSINE; DNA; GLUTAMINE; GUANINE; THYMINE; TRINUCLEOTIDE;

ADULT; ANTICIPATION; ARTICLE; CONTROLLED STUDY; FEMALE; FRANCE; HUMAN; HUMAN CELL; LYMPHOBLASTOID CELL LINE; MAJOR CLINICAL STUDY; MALE; MANIC DEPRESSIVE PSYCHOSIS; POPULATION RESEARCH; PRIORITY JOURNAL; TRINUCLEOTIDE REPEAT;

ADULT; AGE OF ONSET; BIPOLAR DISORDER; BLOTTING, WESTERN; FEMALE; FRANCE; GENE FREQUENCY; HUMANS; MALE; MIDDLE AGED; PEPTIDES; POLYMERASE CHAIN REACTION; TRINUCLEOTIDE REPEATS;

EID: 0032503889     PISSN: 15524841     EISSN: 1552485X     Source Type: Journal    
DOI: 10.1002/(SICI)1096-8628(19980710)81:4<338::AID-AJMG11>3.0.CO;2-M     Document Type: Article

References (22)

1. American Psychiatric Association (1981): "American Psychiatrie Association Diagnostic and Statistical Manual of Mental Disorders (DSM-III-R)." Washington, DC: American Psychiatrie Association.
2. Goodwin FK, Jamison KR (1990): "Manic Depressive Illness." New York: Oxford University Press, p 938.
3. Grigoroiu-Serbanescu M, Wickramaratne PJ, Hodge SE, Milea S, Mihailescu R (1997): Genetic anticipation and imprinting in bipolar I illness. Er J Psychiatry 170:162-166.
4. Hofferbert S, Schanen NC, Chehab F, Francke U (1997): Trinucleotide repeats in the human genome: Size distributions for all possible triplets and detection of expanded disease alleles in a group of Huntington disease individuals by the repeat expansion detection method. Hum Mol Genet 6:77-83.
5. Lindblad K, Nylander PO, De Bruyn A, Sourey D, Zander C, Engstrom C, Holmgren G, Hudson T, Chotai J, Mendlewicz J, van Broeckhoven C, Schalling M, Adolfsson R (1995): Detection of expanded CAG repeats in bipolar affective disorder using the repeat expansion detection (RED) method. Neurobiol Dis 2:55-62.
6. Maxwell ME (1992): "Family Interview for Genetic Studies." Clinical Neurogenetics Branch, Intramural Research Program, NIMH.
7. McInnis MG, McMahon FJ, Chase GA, Simpson SG, Ross CA, DePaulo JR Jr (1993): Anticipation in bipolar affective disorder. Am J Hum Genet 53:385-390.
8. Nurnberger JI Jr, Blehar MC, Kaufmann CA, York-Cooler C, Simpson SG, Harkavy-Friedman J, Severe JB, Malaspina D, Reich T (1994): Diagnostic interview for genetic studies. Rationale, unique features, and training. NIMH Genetics Initiative. Arch Gen Psychiatry 51:849-859, 863-864.
9. Nylander PO, Engstrom C, Chotai J, Wahlstrom J, Adolfsson R (1994): Anticipation in Swedish families with bipolar affective disorder. J Med Genet 31:686-689.
10. O'Donovan MC, Guy C, Craddock N, Murphy KG, Cardno AG, Jones LA, Owen MJ, McGuffin P (1995): Expanded CAG repeats in schizophrenia and bipolar disorder. Nat Genet 10:380-381.
11. O'Donovan MC, Guy C, Craddock N, Bowen T, McKeon P, Macedo A, Maier W, Wildenauer D, Aschauer HN, Sorbi S, Feldman E, Mynett-Johnson L, Claffey E, Nacmias B, Valente J, Dourado A, Grassi E, Lenzinger E, Heiden AM, Moorhead S, Harrison D, Williams J, McGuffin P, Owen MJ (1996): Confirmation of association between expanded CAG/CTG repeats and both schizophrenia and bipolar disorder. Psychol Med 26: 1145-1153.
12. Oruc L, Lindblad K, Verheyen GR, Ahlberg S, Jakovljevic M, Ivezic S, Raeymaekers P, van Broeckhoven C, Schalling M (1997): CAG repeat expansions in bipolar and unipolar disorders. Am J Hum Genet 60: 730-732.
13. Petronis A, Kennedy JL (1995): Unstable genes - Unstable mind? Am J Psychiatry 152:164-172.
14. Reddy PS, Housman DE (1997): The complex pathology of trinucleotide repeats. Curr Opin Cell Biol 9:364-372.
15. Risch N, Botstein D (1996): A manic depressive history. Nat Genet 12:351-353.
16. Schalling M, Hudson TJ, Buetow KH, Housman DE (1993): Direct detection of novel expanded trinucleotide repeats in the human genome. Nat Genet 4:135-139.
17. Sirugo G, Deinard AS, Kidd JR, Kidd KK (1997): Survey of maximum CTG/CAG repeat lengths in humans and non-human primates: Total genome scan in populations using the Repeat Expansion Detection method. Hum Mol Genet 6:403-408.
18. Spitzer RL, Endicott J, Robins E (1975): Research diagnostic diagnostic criteria. Psychopharmacol Bull 11:22-25.
19. Trottier Y, Lutz Y, Stevanin G, et al. (1995): Polyglutamine expansion as a pathological epitope in Huntington's disease and four dominant cerebellar ataxias. Nature 378:403-406.
20. Vincent JB, Klempan T, Parikh SS, Sasaki T, Meltzer HY, Sirugo G, Cola P, Petronis A, Kennedy JL (1996): Frequency analysis of large CAG/ CTG trinucleotide repeats in schizophrenia and bipolar affective disorder. Mol Psychiatry 1:141-148.
21. Zander C, Burgess CE, Johansen J, Lindblad K, Hudson T, Schalling M (1997): Repeat expansion detection. In Taylor GR (ed): "Laboratory Methods for the Detection of Mutations and Polymorphisms in DNA." Boca Raton, FL: CRC Press, Inc., pp 263-271.
22. Zhuchenko O, Bailey J, Bonnen P, Ashizawa T, Stockton DW, Amos C, Dobyns WB, Subramony SH, Zoghbi HY, Lee CC (1997): Autosomal dominant cerebellar ataxia (SCAB) associated with small polyglutamine expansions in the alpha 1A-voltage-dependent calcium channel. Nat Genet 15:62-69.