Reduced growth in response to ganciclovir treatment of subcutaneous xenografts expressing HSV-tk in the vascular compartment

Gene Therapy

Volumn 8, Issue 12, 2001, Pages 913-920

  Mavria, G ^a   Porter, C D ^a  

^a INSTITUTE OF CANCER RESEARCH   (United Kingdom)

Author keywords

Angiogenesis; Endothelial; Gene therapy; HSV tk GCV; Retroviral vector; Tumor vasculature

Indexed keywords

GANCICLOVIR; PRODRUG; THYMIDINE KINASE; VIRUS ENVELOPE PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BLEEDING DISORDER; BLOOD VESSEL; BLOOD VESSEL INJURY; BREAST CARCINOMA; CANCER GROWTH; CELL CYCLE S PHASE; CELL PROLIFERATION; COLON CARCINOMA; CONTROLLED STUDY; DRUG EFFICACY; ECOTROPIC VIRUS; ENDOTHELIUM CELL; ENZYME ACTIVATION; GENETIC TRANSDUCTION; GROWTH INHIBITION; HERPES SIMPLEX VIRUS; HUMAN; HUMAN CELL; IRRADIATION; KAPOSI SARCOMA; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RETROVIRUS; SUBCUTANEOUS TISSUE; TARGET CELL; TUMOR CELL; TUMOR GROWTH; TUMOR VASCULARIZATION; VIRUS ENVELOPE; VIRUS RECOMBINANT; XENOGRAFT;

ANIMALS; ANTIVIRAL AGENTS; BREAST NEOPLASMS; COLONIC NEOPLASMS; ENDOTHELIUM, VASCULAR; FEMALE; GANCICLOVIR; GENE THERAPY; GENETIC VECTORS; HUMANS; MICE; MICE, NUDE; NEOPLASM TRANSPLANTATION; NEOVASCULARIZATION, PATHOLOGIC; PROTEIN-TYROSINE KINASES; RETROVIRIDAE; SIMPLEXVIRUS; TRANSDUCTION, GENETIC; TRANSPLANTATION, HETEROLOGOUS; TUMOR CELLS, CULTURED;

EID: 0034963065     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3301483     Document Type: Article

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