Imaging transmitter release. I. Peeking at the steps preceding membrane fusion

Lasers in Medical Science

Volumn 16, Issue 3, 2001, Pages 149-158

  Oheim, M ^a  

^a MAX PLANCK INSTITUTE OF EXPERIMENTAL MEDICINE   (Germany)

Author keywords

Evanescent wave microscopy; Exocytosis; Fluorescence; Total internal reflection; Vesicle dynamics

Indexed keywords

NEUROTRANSMITTER;

ELECTROCHEMISTRY; ELECTROPHYSIOLOGY; EXOCYTOSIS; IMAGING; KINETICS; LASER MICROSCOPY; MEMBRANE FUSION; MEMBRANE TRANSPORT; NEUROTRANSMITTER RELEASE; PATCH CLAMP; PRIORITY JOURNAL; QUANTITATIVE ASSAY; REVIEW; TECHNIQUE;

EID: 0034958325     PISSN: 02688921     EISSN: None     Source Type: Journal    
DOI: 10.1007/PL00011349     Document Type: Review

References (93)

1. Vesicle hypothesis of the release of quanta of acetylcholine
2. Quantal components of the end-plate potential
3. The synaptic vesicle cycle: A cascade of protein-protein interactions
4. Throttles and dampers: Controlling the engine of membrane fusion
5. Pre- and post-synaptic whole-cell recordings in the medial nucleus of the trapezoid body of the rat
6. Presynaptic mechanism for phorbol-ester induced synaptic potentiation
7. Relationship between presynaptic calcium current and postsynaptic potential in squid giant synapse
8. The role of calcium in regulating neuro-transmitter release in the squid giant synapse
9. Regulated exocytosis
10. Exocytosis in pituitary cells
11. Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches
12. Discrete changes in of cell membrane capacitance observed under conditions of enhanced secretion in bovine adrenal chromaffin cells
13. Temporarily resolved catecholamine spikes correspond to single vesicle release from individual chromaffin granules
14. Delay in vesicle fusion revealed by electrochemical monitoring of single secretory events in adrenal chromaffin cells
15. Optical analysis of synaptic vesicle recycling at the frog neuromuscular junction
16. Measuring serotonin distribution in live cells with three-photon excitation
17. Transport, docking and exocytosis of single secretory granules in live chromaffin cells
18. The kinetics of exocytosis and endocytosis in the synaptic terminals of goldfish retinal bipolar cells
19. The kinetics of synaptic vesicle recycling measured at single presynaptic boutons
20. Techniques for membrane capacitance measurements
21. Spatial and temporal aspects of Ca changes in secretional control
22. Calcium requirements for secretion in bovine chromaffin cells
23. 2+ microdomains: New tools for understanding their roles in neurotransmitter release
24. Exocytosis
25. Electrochemical detection of secretion from single cells
26. Secretion without full fusion
27. Release of secretory products during transient vesicle fusion
28. Currents through the fusion pore that forms during exocytosis of a secretory vesicle
29. High calcium concentrations shift the mode of exocytosis to the kiss-and-run mechanism
30. Temporal characteristics of quantal secretion of catecholamines from adrenal medullary cells
31. Regulations of dense core release from neuroendocrine cells revealed by imaging single exocytic events
32. The exocytotic event in chromaffin cells revealed by patch amperometry
33. Extrasynaptic vesicular transmitter release from the somata of substantia nigra neurons in rat midbrain slices
34. Analysis of diffusional broadening of vesicular packets of catecholamines released from biological cells during exocytosis
35. Kinetics of exocytosis in adrenal chromaffin cells
36. 2+ acts by two separate pathways to modulate the supply of release-competent vesicles in chromaffin cells
37. Rapid exocytosis in single chromaffin cells recorded from mouse adrenal slices
38. Multiple kinetic components of exocytosis distinguished by neurotoxin sensitivity
39. 2+-dependent exocytosis: Implications of kinetic diversity for secretory function
40. Optical detection of quantal presynaptic membrane turnover
41. Transport, capture and exocytosis of single synaptic vesicles at active zones
42. Observing secretory granules with a multiangle evanescent-wave microscope
43. Neuronal peptide release is limited by secretory granule movement
44. The synaptic vesicle cycle
45. Vesicle pool mobilization during action potential firing at hippocampal synapses
46. Photon upmanship - Why multiphoton imaging is more than a gimmick
47. Multifocal multiphoton microscopy
48. Real time two-photon absorption microscopy using multiple point excitation
49. Video-rate scanning two-photon excitation fluorescence microscope and ratio imaging with cameleons
50. Real-time 2-photon confocal microscopy using a femtosecond, amplified ti-sapphire system
51. Fast scanning and efficient photodetection in a simple two-photon microscope
52. Total internal reflection fluorescence
53. Evanescent waves in optical imaging
54. Total reflection fluorescence (TRF)
55. Cell-substrate contacts illuminated by TIRF
56. Fluorescence emission at dielectric and metal-film interfaces
57. Fluorescence of adsorbed protein layers: Quantitation of total internal reflection fluorescence
58. Evanescent detection of adsorbed protein concentration-distance profiles: Fit of simple models to variable-angle total internal reflection fluorescence data
59. General electromagnetic theory of total internal reflection fluorescence: The quantitative basis for mapping cell-substratum topography
60. Topography of cell-glass apposition revealed by total internal reflection fluorescence of volume markers
61. Structural organization of interphase 3T3 fibroblasts studied by TIRFM
62. Mapping fluorophore distributions in 3 dimensions by quantitative multi-angle total internal reflection fluorescence microscopy (MA-TIRFM)
63. Translational diffusion of bovine prothrombin fragment 1 weakly bound to supported planar membranes: Measurement by total internal reflection with fluorescence pattern photobleaching recovery
64. Competitive protein adsorption-studied with tiff and ellipsometry
65. 2+ sparks within 200 nm of the sarcolemma of rat ventricular cells: Evidence from total internal reflection fluorescence microscopy
66. Imaging and time-resolved spectroscopy of single molecules at an interface
67. Direct observation of single kinesin molecules moving along microtubules
68. 2+-triggered peptide secretion in single cells imaged with green fluorescent protein and evanescent-wave microscopy
69. The last few milliseconds in the life of a secretory granule. Docking dynamics and fusion visualized by total internal reflection fluorescence microscopy (TIRFM)
70. Evanescent-wave microscopy: A new tool to gain insight into the control of transmitter release
71. Tracking individual granules through the actin cortex
72. Tracking single secretory granules in live chromaffin cells by evanescent-field fluorescence microscopy
73. Quantitative analysis of exocytosis directly visualised in living chromaffin cells
74. Optical detection of calcium dependent ATP release from stimulated medullary chromaffin cells
75. Imaging exocytosis and endocytosis
76. Synaptic vesicles retain their identity through the endocytic cycle
77. Simultaneous independent measurement of endocytosis and exocytosis
78. Imaging synaptic activity in intact brain and slices with FM1-43 in C. elegans, lamprey and rat
79. The pH-sensitive dye acridine orange as a tool to monitor exocytosis/endocytosis in synaptosomes
80. Targeting of green fluorescent protein to neuroendocrine secretory granules: A new tool for real time studies of regulated protein secretion
81. Role of rab3A-binding domain in targeting of rabphilin-3A to vesicle membranes of PC12 cells
82. Engineering green fluorescent protein for improved brightness, longer wavelengths and fluorescence resonance energy transfer
83. 2+ activity directly controls adrenergic secretion in rat chromaffin cells
84. Fusion of constitutive membrane traffic with the cell surface observed by evanescent wave microscopy
85. ER-to-Golgi transport of vsv g-gfp chimeras visualized in living cells
86. Unravelling Golgi membrane traffic with green fluorescent protein chimeras
87. Endocytic vesicles move at the tips of actin tails in cultured mast cells
88. Role of actin cortex in the subplasmalemmal transport of secretory granules in PC-12 cells
89. 2+ channel trigger secretion with different efficacies in chromaffin cells
90. Imaging constitutive exocytosis with total internal reflection fluorescence microscopy
91. Exocytosis: Meltdown of the core
92. Secretion: Dense-core vesicles can kiss-and-run too