Comparison of in vitro and in vivo human skin responses to consumer products and ingredients with a range of irritancy potential

Toxicological Sciences

Volumn 48, Issue 2, 1999, Pages 218-229

  Perkins, Mary A ^a   Osborne, Rosemarie ^a   Rana, Fuz R ^a   Ghassemi, Annahita ^a   Robinson, Michael K ^a  

^a PROCTER AND GAMBLE COMPANY   (United States)

Author keywords

Aspartate aminotransferase; In vitro skin cultures; Interleukin 1 (IL 1 ); Lactate dehydrogenase; Skin irritation potential; Surfactants

Indexed keywords

ANTIPERSPIRANT AGENT; ASPARTATE AMINOTRANSFERASE; COSMETIC; DEODORANT AGENT; DOMESTIC CHEMICAL; ENZYME; INTERLEUKIN 1ALPHA; IRRITANT AGENT; LACTATE DEHYDROGENASE; SURFACTANT;

ADULT; AGED; ARTICLE; CELL VIABILITY; COMPARATIVE STUDY; CONTROLLED STUDY; EDEMA; ENZYME RELEASE; ERYTHEMA; FEMALE; HUMAN; HUMAN EXPERIMENT; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; MALE; NORMAL HUMAN; PATCH TEST; SKIN CULTURE; SKIN IRRITATION;

ASPARTATE AMINOTRANSFERASES; CELL SURVIVAL; CELLS, CULTURED; EDEMA; ERYTHEMA; HUMANS; INTERLEUKIN-1; IRRITANTS; KERATINOCYTES; L-LACTATE DEHYDROGENASE; SKIN; SKIN TESTS; TIME FACTORS;

EID: 0032914723     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/48.2.218     Document Type: Article

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