Exploring the minimal substrate requirements for trans-cleavage by RNase P holoenzymes from Escherichia coli and Bacillus subtilis

Molecular Microbiology

Volumn 41, Issue 1, 2001, Pages 131-143

  Hansen, Annika ^a   Pfeiffer, Thomas ^a,d   Zuleeg, Tilman ^b   Limmer, Stefan ^b   Ciesiolka, Jerzy ^c   Feltens, Ralph ^a   Hartmann, Roland K ^a  

^a UNIVERSITY OF LÜBECK   (Germany)

^b UNIVERSITY OF BAYREUTH   (Germany)

^c INSTITUTE OF BIOORGANIC CHEMISTRY   (Poland)

^d Euroimmun ^*  (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL ENZYME; HOLOENZYME; HYBRID PROTEIN; OLIGONUCLEOTIDE; PROTEIN SUBUNIT; RIBONUCLEASE P; TRANSFER RNA;

ARTICLE; BACILLUS SUBTILIS; CHEMICAL MODIFICATION; ESCHERICHIA COLI; MODEL; NONHUMAN; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN STRUCTURE; TURNOVER TIME;

BACILLUS SUBTILIS; ENDORIBONUCLEASES; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; HOLOENZYMES; KINETICS; OLIGONUCLEOTIDES; RIBONUCLEASE P; RNA, BACTERIAL; RNA, CATALYTIC; SUBSTRATE SPECIFICITY;

EID: 0034944725     PISSN: 0950382X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2958.2001.02467.x     Document Type: Article

References (43)

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2. Ribonuclease P
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10. Inside a living cell
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14. Role of the D arm and the anticodon arm in tRNA recognition by eubacterial and eukaryotic RNase P enzymes
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16. 2 groups of E. coli RNase P RNA involved in intramolecular tertiary contacts and direct interactions with tRNA
17. Distinct modes of mature and precursor tRNA binding to Escherichia coli RNase P RNA revealed by NAIM analyses
18. Base pairing between Escherichia coli RNase P RNA and its substrate
19. A tRNA-like structure is present in 10Sa RNA, a small stable RNA from Escherichia coli
20. Different cleavage sites are aligned differently in the active site of M1 RNA, the catalytic subunit of Escherichia coli RNase P
21. Asp
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31. Protein component of the ribozyme ribonuclease P alters substrate recognition by directly contacting precursor tRNA
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41. Compilation of tRNA sequences and sequences of tRNA genes
42. Several regions of a tRNA precursor determine the Escherichia coli RNase P cleavage site
43. Role of metal ions in the hydrolysis reaction catalyzed by RNase P RNA from Bacillus subtilis