Distinct modes of mature and precursor tRNA binding to Escherichia coli RNase P RNA revealed by NAIM analyses

RNA

Volumn 7, Issue 4, 2001, Pages 553-564

  Heide, Corinna ^a   Busch, Silke ^a,b   Feltens, Ralph ^a   Hartmann, Roland K ^a  

^a UNIVERSITY OF LÜBECK   (Germany)

^b UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

Author keywords

c7 deaza modifications; Inosine modifications; Nucleotide analog interference mapping (NAIM); PtRNA processing by E. coli RNase P RNA; tRNA binding to E. coli RNase P RNA

Indexed keywords

RIBONUCLEASE P; RNA; TRANSFER RNA;

ARTICLE; CHEMICAL MODIFICATION; CHEMICAL REACTION; CONFORMATION; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; RNA BINDING; RNA PROCESSING; RNA STRUCTURE;

ANTICODON; AZA COMPOUNDS; BASE SEQUENCE; BINDING SITES; ENDORIBONUCLEASES; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; INOSINE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NUCLEIC ACID CONFORMATION; PHOSPHATES; RIBONUCLEASE P; RNA PRECURSORS; RNA PROCESSING, POST-TRANSCRIPTIONAL; RNA, BACTERIAL; RNA, CATALYTIC; RNA, TRANSFER, GLY;

EID: 0035011793     PISSN: 13558382     EISSN: None     Source Type: Journal    
DOI: 10.1017/S1355838201001765     Document Type: Article

References (39)

1. Ribonuclease P
2. 74 in the reaction catalyzed by Escherichia coli RNase P RNA
3. Comparative photo-crosslinking analysis of the tertiary structure of Escherichia coli and Bacillus subtilis RNase P RNAs
4. p oxygen of the scissile bond
5. Analysis of the role of phosphate oxygens in the group I intron from Tetrahymena
6. Enzymatic synthesis of 2′-modified nucleic acids: Identification of important phosphate and ribose moieties in RNase P substrates
7. Ribonuclease P: Unity and diversity in a tRNA processing ribozyme
8. Differences in the interaction of Escherichia coli RNase P RNA with tRNAs containing a short or a long extra arm
9. Modification interference approach to detect ribose moieties important for the optimal activity of a ribozyme
10. A physical assay for and kinetic analysis of the interactions between M1 RNA and tRNA precursor substrates
11. The RNA moiety of ribonuclease P is the catalytic subunit of the enzyme
12. Gel retardation analysis of E. coli M1 RNA-tRNA complexes
13. Role of the D arm and the anticodon arm in tRNA recognition by eubacterial and eukaryotic RNase P enzymes
14. Kinetics and thermodynamics of the RNase P RNA cleavage reaction: Analysis of tRNA 3′-end variants
15. p-phosphorothioate modifications in RNase P RNA that interfere with tRNA binding
16. 2 groups of Escherichia coli RNase P RNA involved in intramolecular tertiary contacts and direct interactions with tRNA
17. Crystal structure of yeast phenylalanine transfer RNA
18. A crystallographic study of metal-binding to yeast phenylalanine transfer RNA
19. 2+ in 15-year old crystals
20. The methylation of one specific guanosine in a pre-tRNA prevents cleavage by RNase P and by the catalytic M1 RNA
21. Substrate recognition by RNase P and by the catalytic M1 RNA: Identification of possible contact points in pre-tRNAs
22. Identification by modification-interference of purine N-7 and ribose 2′-OH groups critical for catalysis by bacterial ribonuclease P
23. Base pairing between Escherichia coli RNase P RNA and its substrate
24. Different cleavage sites are aligned differently in the active site of M1 RNA, the catalytic subunit of Escherichia coli RNase P
25. Recognition of the T stem-loop of a pre-tRNA substrate by the ribozyme from Bacillus subtilis ribonuclease P
26. Derivation of the three-dimensional architecture of bacterial ribonuclease P RNAs from comparative sequence analysis
27. 2+ ions by ribonuclease P
28. Interaction of the 3′-end of tRNA with ribonuclease P RNA
29. Probing of tertiary interactions in RNA: 2′-hydroxyl-base contacts between the RNase P RNA and pre-tRNA
30. RNase P RNAs from some Archaea are catalytically active
31. Important 2′-hydroxyl groups in model substrates for M1 RNA, the catalytic RNA subunit of RNase P from Escherichia coli
32. Multiple binding modes of substrate to the catalytic RNA subunit of RNase P from Escherichia coli
33. Structural domains of transfer RNA molecules
34. Transfer RNA: Molecular structure, sequence, and properties
35. Multiple magnesium ions in the ribonuclease P reaction mechanism
36. p-phosphorothioate modification in the precursor tRNA at the RNase P cleavage site
37. Crystallographic refinement of yeast aspartic acid transfer RNA
38. Restrained refinement of the monoclinic form of yeast phenylalanine transfer RNA. Temperature factors and dynamics, coordinated waters, and base-pair propeller twist angles
39. Mapping in three dimensions of regions in a catalytic RNA protected from attack by an Fe(II)-EDTA reagent