Macrophage stimulation with murabutide, an HIV-suppressive muramyl peptide derivative, selectively activates extracellular signal-regulated kinases 1 and 2, C/EBPβ and STAT 1: Role of CD14 and Toll-like receptors 2 and 4

European Journal of Immunology

Volumn 31, Issue 7, 2001, Pages 1962-1971

  Vidal, Vincent F ^a   Castran, Nathalie ^a   Riendeau, Carrie J ^b   Kornfeld, Hardy ^b   Darcissac, Edith C A ^a   Capron, Andr ^b   Bahr, George M ^a,c  

^a INSTITUT PASTEUR DE LILLE   (France)

^b ISTAC Biotechnology   (France)

^c BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Immunomodulator; Macrophage; Protein kinase; Transcription factor

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; CD14 ANTIGEN; CELL EXTRACT; CELL SURFACE RECEPTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IMMUNOMODULATING AGENT; IMMUNOSTIMULATING AGENT; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MURABUTIDE; MURAMYL PEPTIDE; PEPTIDOGLYCAN; STAT 1 PROTEIN; STAT 3 PROTEIN; STAT 5 PROTEIN; STAT PROTEIN; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL CELL WALL; CELL ACTIVATION; CELL STIMULATION; CONTROLLED STUDY; DRUG MECHANISM; DRUG POTENCY; DRUG SAFETY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS; MACROPHAGE; MONOCYTE; NONHUMAN; PRIORITY JOURNAL; SALMONELLA ENTERITIDIS; SIGNAL TRANSDUCTION; VIRUS REPLICATION; VIRUS TRANSCRIPTION;

ACETYLMURAMYL-ALANYL-ISOGLUTAMINE; ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTI-HIV AGENTS; ANTIGENS, CD14; CCAAT-ENHANCER-BINDING PROTEIN-BETA; CELL LINE; CELLS, CULTURED; CHO CELLS; CRICETINAE; DNA-BINDING PROTEINS; DROSOPHILA PROTEINS; ENZYME ACTIVATION; HUMANS; MACROPHAGES; MEMBRANE GLYCOPROTEINS; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; MONOCYTES; PHOSPHORYLATION; RECEPTORS, CELL SURFACE; SIGNAL TRANSDUCTION; STAT1 TRANSCRIPTION FACTOR; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 4; TOLL-LIKE RECEPTORS; TRANS-ACTIVATORS; TRANSCRIPTION FACTOR AP-1;

EID: 0034938974     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-4141(200107)31:7<1962::AID-IMMU1962>3.0.CO;2-V     Document Type: Article

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