Triple helix-forming oligonucleotides conjugated to indolocarbazole poisons direct topoisomerase I-mediated DNA cleavage to a specific site

Bioconjugate Chemistry

Volumn 12, Issue 4, 2001, Pages 501-509

  Arimondo, P B ^a   Bailly, C ^a   Boutorine, A S ^b   Moreau, P ^c   Prudhomme, M ^c   Sun, J S ^b   Garestier, T ^b   Helene C ^b  

^a CENTRE OSCAR LAMBRET   (France)

^b MUSÉUM NATIONAL D'HISTOIRE NATURELLE   (France)

^c UNIVERSITÉ CLERMONT AUVERGNE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOTHERAPY; DISEASES; DNA;

CAMPTOTHECINS; CANCER CHEMOTHERAPY; DNA CLEAVAGE; DNA TOPOISOMERASE I; INDOLOCARBAZOLES; OLIGONUCLEOTIDE CONJUGATES; REBECCAMYCIN; SPECIFIC SITES; THERAPEUTIC TARGETS; TOPOISOMERASE I;

OLIGONUCLEOTIDES;

EID: 0034924635     PISSN: 10431802     EISSN: None     Source Type: Journal    
DOI: 10.1021/bc000162k     Document Type: Article

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