Effects of phencyclidine on prepulse inhibition of acoustic startle response in the macaque

Psychopharmacology

Volumn 156, Issue 2-3, 2001, Pages 165-168

  Javitt, D C ^a   Lindsley, R W ^a  

^a NATHAN S KLINE INSTITUTE FOR PSYCHIATRIC RESEARCH   (United States)

Author keywords

Event related potentials; Glutamate; N Methyl D aspartate; Schizophrenia; Thought disorder

Indexed keywords

PHENCYCLIDINE;

ACOUSTIC REFLEX; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHANNEL GATING; CONTROLLED STUDY; DRUG EFFECT; EVENT RELATED POTENTIAL; MONKEY; NEUROPHYSIOLOGY; NEUROTRANSMITTER RELEASE; NONHUMAN; PREPULSE INHIBITION; PRIORITY JOURNAL; SCHIZOPHRENIA; SENSORIMOTOR FUNCTION; STARTLE REFLEX; STIMULUS RESPONSE; THOUGHT DISORDER;

ACOUSTIC STIMULATION; ANIMALS; ELECTROMYOGRAPHY; EVOKED POTENTIALS; HALLUCINOGENS; MACACA FASCICULARIS; PHENCYCLIDINE; RECEPTORS, N-METHYL-D-ASPARTATE; STARTLE REACTION;

EID: 0034915264     PISSN: 00333158     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002130100758     Document Type: Article

References (27)

1. Effects of clonidine and diazepam on the acoustic startle response and on its inhibition by "prepulses" in man
2. Repeated testing of prepulse inhibition and habituation of the startle reflex: A study in healthy human controls
3. Effects of the PCP analog dizocilpine on sensory gating: Potential relevance to clinical subtypes of schizophrenia
4. Phencyclidine-induced deficits in prepulse inhibition of startle are blocked by prazosin, an alpha-1 noradrenergic antagonist
5. Disruption of prepulse inhibition and increases in locomotor activity by competitive N-methyl-D-aspartate receptor antagonists in rats
6. Sensorimotor gating and schizophrenia. Human and animal model studies
7. Gating and habituation of the startle reflex in schizophrenic patients
8. Symptom correlates of prepulse inhibition deficits in male schizophrenic patients
9. Prepulse inhibition and habituation of the startle response are stable neurobiological measures in a normal male population
10. Modification of the acoustic startle-reflex eyeblink: A tool for investigating early and late attentional processes
11. Startle response models of sensorimotor gating and habituation deficits in schizophrenia
12. Effects of the hallucinogen psilocybin on habituation and prepulse inhibition of the startle reflex in humans
13. Recent advances in the phencyclidine model of schizophrenia
14. Schizophrenia-like deficits in auditory P1 and N1 refractoriness induced by the psychomimetic agent phencyclidine (PCP)
15. Prepulse inhibition of the startle response in men with schizophrenia: Effects of age of onset of illness, symptoms, and medication
16. Phencyclidine (PCP) induced deficits of prepulse inhibition in monkeys
17. The effects of phencyclidine and ketamine on sensory thresholds and reaction times in the baboon
18. Effects of phencyclidine and phencyclidine biologs on sensorimotor gating in the rat
19. Parametric determinants in pre-stimulus modification of acoustic startle: Interaction with ketamine
20. Effects of sustained phencyclidine exposure on sensorimotor gating of startle in rats
21. Impaired prepulse inhibition of acoustic startle in schizophrenia
22. Information-processing deficits and thought disorder in schizophrenia
23. Sensorimotor gating and thought disturbance measured in close temporal proximity in schizophrenic patients
24. Using an animal model of deficient sensorimotor gating to study the pathophysiology and new treatments of schizophrenia
25. Seroquel, clozapine and chlorpromazine restore sensorimotor gating in ketamine-treated rats
26. The effects of low dose ketamine on sensory gating, neuroendocrine secretion and behavior in healthy human subjects
27. Opposite effects of 3,4-methylenedioxymethamphetamine (MDMA) on sensorimotor gating in rats versus healthy humans