Crucial amino acid residues of mouse CD1d for glycolipid ligand presentation to Vα14 NKT cells

International Immunology

Volumn 13, Issue 7, 2001, Pages 853-861

  Kamada, Noriaki ^a,b   Iijima, Hiroshi ^c   Kimura, Kaname ^c   Harada, Michishige ^a   Shimizu, Eiko ^a   Motohashi, Shin Ichiro ^a   Kawano, Tetsu ^a   Shinkai, Hiroshi ^b   Nakayama, Toshinori ^a   Sakai, Teruyuki ^c   Brossay, Laurent ^d   Kronenberg, Mitchell ^d   Taniguchi, Masaru ^a  

^a JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^b CHIBA UNIVERSITY   (Japan)

^c KIRIN BREWERY CO LTD   (Japan)

^d LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY   (United States)

Author keywords

Docking modeling; NKT cell receptor; galactosylceramide

Indexed keywords

AMIDE; AMINO ACID; ARGININE; ASPARTIC ACID; CARBOHYDRATE; CD1 ANTIGEN; GALACTOSYLCERAMIDE; GLUTAMIC ACID; GLYCOLIPID; LIGAND; LYMPHOCYTE ANTIGEN RECEPTOR;

ANALYSIS; ANTIGEN EXPRESSION; ANTIGEN PRESENTATION; ANTIGEN RECOGNITION; ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; GENE MUTATION; GENETIC TRANSFECTION; LYMPHOCYTE ACTIVATION; MOLECULAR INTERACTION; MOLECULAR MODEL; MOUSE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL;

EID: 0034915233     PISSN: 09538178     EISSN: None     Source Type: Journal    
DOI: 10.1093/intimm/13.7.853     Document Type: Article

References (42)

1. + NK T cells in the early stages of embryogenesis
2. α14 NKT cells in IL-12-mediated rejection of tumors
3. α14 NKT cells by granulocyte/macrophage colony-stimulating factor
4. Sequence and expression of transcripts of the T-cell antigen receptor α-chain gene in a functional, antigen-specific suppressor-T-cell hybridoma
5. - T cells in mice and humans
6. + T cell populations
7. - T cells
8. - and heterogeneous with respect to TCR β expression
9. CD1d-mediated recognition of an α-galactosylceramide by natural killer T cells is highly conserved through mammalian evolution
10. + NK T lymphocytes
11. α14 NKT cells by glycosylceramides
12. A novel recognition motif of human NKT antigen receptor for a glycolipid ligand
13. + natural killer T cells activated by α-galactosylceramide (KRN7000) have cytotoxic anti-tumour activity through mechanisms distinct from T cells and natural killer cells
14. α24TCR-mediated manner
15. CD1d-restricted recognition of synthetic glycolipid antigens by human natural killer T cells
16. + NKT cells activated by α-glycosylceramide-pulsed monocyte-derived dendritic cells
17. Crystal structure of mouse CD1: An MHC-like fold with a large hydrophobic binding groove
18. Binding and antigen presentation of ceramide-containing glycolipids by soluble mouse and human CD1d molecules
19. Syntheses of biotinylated α-galactosylceramides and their effects on the immune system and CD1 molecules
20. Molecular recognition of lipid antigens by T cell receptors
21. Structural requirements for galactosylceramide recognition by CD1-restricted NK T cells
22. Structure-activity relationship of α-galactosylceramides against B16-bearing mice
23. Immunostimulatory activities of monoglycosylated α-D-pyranosylceramides
24. Immunostimulatory and antitumor activities of monoglycosylceramides having various sugar moieties
25. Structure-activity relationship and conformational analysis of monoglycosylceramides on the syngeneic mixed leukocyte reaction
26. Nonclassical behavior of the mouse CD1 class I-like molecule
27. α14 NKT cell-mediated cytotoxicity by interleukin 4 in an autocrine mechanism resulting in the development of concanavalin A-induced hepatitis
28. Murine CD1d-restricted T cell recognition of cellular lipids
29. Effects of α- and β-galactosylated C2-ceramides on the immune system
30. Differences in the ligand specificity between CD1d-restricted T cells with limited and diverse T-cell receptor repertoire
31. Merck molecular force field. I. Basis, form, scope, parameterization, and performance of MMFF94
32. Merck molecular force field. II. MMFF94 van der Waals and electrostatic parameters for intermolecular interactions
33. Merck molecular force field. III. Molecular geometries and vibrational frequencies for MMFF94
34. Merck molecular force field. IV. Conformational energies and geometries for MMFF94
35. Merck molecular force field. V. Extension of MMFF94 using experimental data, additional computational data, and empirical rules
36. The CD1 family: A third lineage of antigen-presenting molecules
37. α24 NKT cells
38. - T cells
39. Two human T cell receptors bind in a similar diagonal mode to the HLA-A2/Tax peptide complex using different TCR amino acids
40. Structural basis of plasticity in T cell receptor recognition of a self peptide-MHC antigen
41. The crystal structure of a T cell receptor in complex with peptide and MHC class II
42. Structural requirements for antigen presentation by mouse CD1