메뉴 건너뛰기




Volumn 54, Issue 4, 2001, Pages 206-214

What we could do now: Molecular pathology of colorectal cancer

Author keywords

Colorectal cancer; Genes; Prognosis

Indexed keywords

PROTEIN P27; PROTEIN P53;

EID: 0034907056     PISSN: 13668714     EISSN: None     Source Type: Journal    
DOI: 10.1136/mp.54.4.206     Document Type: Conference Paper
Times cited : (64)

References (153)
  • 20
    • 0028033603 scopus 로고
    • Loss of apc protein expressed by human colonic epithelial cells and the appearance of a specific low molecular weight form is associated with apoptosis in vitro
    • (1994) Int J Cancer , vol.59 , pp. 56-64
    • Browne, S.1    Williams, A.2    Hague, A.3
  • 21
    • 0028409177 scopus 로고
    • The tumour suppressor APC product is associated with cell adhesion
    • (1994) Bioessays , vol.16 , pp. 225-227
    • Burchill, S.A.1
  • 24
  • 32
    • 0028979727 scopus 로고
    • Adenomatous polyposis coli gene mutations in ulcerative colitis associated dysplasias and cancers versus sporadic colon neoplasms
    • (1995) Cancer Res , vol.55 , pp. 2035-2038
    • Tarmin, L.1    Yin, J.2    Harpaz, N.3
  • 38
    • 0031004088 scopus 로고    scopus 로고
    • Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome
    • (1997) Nat Genet , vol.16 , pp. 64-67
    • Liaw, D.1    Marsh, D.J.2    Li, J.3
  • 42
    • 0023898932 scopus 로고
    • The ras gene family and human carcinogenesis
    • (1988) Murat Res , vol.195 , pp. 255-271
    • Bos, J.L.1
  • 44
    • 0028931739 scopus 로고
    • Mutant K ras in apparently normal mucosa of colorectal cancer patients. Its potential as a biomarker of colorectal tumorigenesis
    • (1995) Cancer , vol.75 , Issue.SUPPL. 6 , pp. 1520-1526
    • Minamoto, T.1    Yamashita, N.2    Ochiai, A.3
  • 45
    • 0028931923 scopus 로고
    • Aberrant crypt foci and K ras mutations: Earliest recognised players or innocent bystanders in colon carcinogenesis?
    • (1995) Gastroenterology , vol.108 , pp. 600-603
    • Pretlow, T.P.1
  • 46
    • 0029003648 scopus 로고
    • Role of aberrant crypt foci in understanding the pathogenesis of colon cancer
    • (1995) Cancer Lett , vol.93 , pp. 55-71
    • Bird, R.P.1
  • 52
    • 0027109075 scopus 로고
    • Cancer. p53, guardian of the genome
    • (1992) Nature , vol.358 , pp. 15-16
    • Lane, D.P.1
  • 55
    • 0028873269 scopus 로고
    • Somatic spectrum of cancer associated single basepair substitutions in the p53 gene is determined mainly by endogenous mechanisms of mutation and by selection
    • (1995) Hum Mutat , vol.5 , pp. 48-57
    • Krawczak, M.1    Smith, S.B.2    Schmidtke, J.3
  • 59
    • 13344279424 scopus 로고    scopus 로고
    • The FHIT gene, spanning the chromosome 3p14.2 fragile site and renal carcinoma associated t(3 ,8) breakpoint, is abnormal in digestive tract cancers
    • (1996) Cell , vol.84 , pp. 587-597
    • Ohta, M.1    Inoue, H.2    Cotticelli, M.G.3
  • 61
    • 0028845142 scopus 로고
    • Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers
    • (1995) Cancer Res , vol.55 , pp. 4525-4530
    • Herman, J.G.1    Merlo, A.2    Mao, L.3
  • 62
    • 0028875205 scopus 로고
    • Methylation of the 5′CpG island of the p16/CDKN2 tumor suppressor gene in normal and transformed human tissues correlates with gene silencing
    • (1995) Cancer Res , vol.55 , pp. 4531-4535
    • Gonzalez, Z.M.1    Bender, C.M.2    Yang, A.S.3
  • 64
    • 0028788862 scopus 로고
    • Deletion mapping defines different regions in 1p34.2 pter that may harbor genetic information related to human colorectal cancer
    • (1995) Oncogene , vol.11 , pp. 1357-1362
    • Praml, C.1    Finke, L.H.2    Herfarth, C.3
  • 71
    • 0028276666 scopus 로고
    • Clinical and pathological characteristics of sporadic colorectal carcinomas with DNA replication errors in microsatellite sequences
    • (1994) Am J Pathol , vol.145 , pp. 148-156
    • Kim, H.1    Jen, J.2    Vogelstein, B.3
  • 81
    • 0028973429 scopus 로고
    • Overexpression of nm23 H1 and nm23 H2 genes in colorectal carcinomas and loss of nm23 H1 expression in advanced tumour stages
    • (1995) Gut , vol.37 , pp. 712-720
    • Martinez, J.A.1    Prevot, S.2    Nordlinger, B.3
  • 83
    • 0027973944 scopus 로고
    • Frequency of allele loss of DCC, p53, RBI, WT1, NF1, NM23 and APC/MCC in colorectal cancer assayed by fluorescent multiplex polymerase chain reaction
    • (1994) Br J Cancer , vol.70 , pp. 813-818
    • Cawkwell, L.1    Lewis, F.A.2    Quirke, P.3
  • 84
    • 0028301964 scopus 로고
    • Prognostic significance of the loss of heterozygosity of nm23 h1 and p53 genes in human colorectal carcinomas
    • (1994) Cancer , vol.73 , pp. 2913-2921
    • Campo, E.1    Miquel, R.2    Jares, P.3
  • 85
    • 0028670648 scopus 로고
    • Positive relationship between expression of CD44 and hepatic metastases in colorectal cancer
    • (1994) Pathobiology , vol.62 , pp. 172-179
    • Ichikawa, W.1
  • 87
    • 0029021505 scopus 로고
    • Recurrent deletions involving chromosomes 1, 5, 17, and 18 in colorectal carcinoma: Possible role in biological and clinical behavior of tumors
    • (1995) Anticancer Res , vol.15 , pp. 13-24
    • Gerdes, H.1    Chen, Q.2    Elahi, A.H.3
  • 89
    • 0031014938 scopus 로고    scopus 로고
    • The significance of allelic deletions and aneuploidy in colorectal carcinoma. Results of a 5 year follow up study
    • (1997) Cancer , vol.79 , pp. 233-244
    • Cohn, K.H.1    Ornstein, D.L.2    Wang, F.3
  • 115
  • 124
    • 0033831989 scopus 로고    scopus 로고
    • Prognostic significance of extensive microsatellite instability in sporadic clinicopathological stage C colorectal cancer
    • (2000) Br J Surg , vol.87 , pp. 1197-1202
    • Wright, C.M.1    Dent, O.F.2    Barker, M.3
  • 133
    • 0028942692 scopus 로고
    • Immunohistochemical analysis of p53 in colorectal cancer regarding clinicopathological correlation and prognostic significance
    • (1995) J Surg Oncol , vol.58 , pp. 125-128
    • Tomoda, H.1    Kakeji, Y.2
  • 134
  • 149
    • 0031048236 scopus 로고    scopus 로고
    • Increased proteasome dependent degradation of the cyclin dependent kinase inhibitor p27 in aggressive colorectal carcinomas
    • (1997) Nat Med , vol.3 , pp. 231-234
    • Loda, M.1    Cukor, B.2    Tam, S.W.3
  • 150
    • 0033986568 scopus 로고    scopus 로고
    • Prognostic significance of p27 (kip1) protein expression and spontaneous apoptosis in patients with colorectal adenocarcinomas
    • (2000) Oncology , vol.58 , pp. 45-51
    • Tenjo, T.1    Toyoda, M.2    Okuda, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.