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Volumn 28, Issue 5, 1996, Pages 389-399

Genetic pathways in colorectal cancer

Author keywords

Adenoma carcinoma sequence; Colorectal cancer; Genetic pathways; Mutation selection

Indexed keywords

CANCER GENETICS; CARCINOGENESIS; COLORECTAL CANCER; HUMAN; PRIORITY JOURNAL; REVIEW;

EID: 0029936242     PISSN: 03090167     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2559.1996.339381.x     Document Type: Review
Times cited : (54)

References (114)
  • 2
  • 3
    • 0028264419 scopus 로고
    • Detection of K-ras mutation in colonic effluent samples from patients without evidence of colorectal carcinoma
    • Tobi M, Luo FC, Ronai Z. Detection of K-ras mutation in colonic effluent samples from patients without evidence of colorectal carcinoma. J. Natl. Cancer Inst. 1994; 86; 1007-1010.
    • (1994) J. Natl. Cancer Inst. , vol.86 , pp. 1007-1010
    • Tobi, M.1    Luo, F.C.2    Ronai, Z.3
  • 4
    • 0026537986 scopus 로고
    • Identification of ras oncogene mutations in the stool of patients with curable colorectal tumors
    • Sidransky D, Tokino T, Hamilton SR et al. Identification of ras oncogene mutations in the stool of patients with curable colorectal tumors. Science 1992; 256; 102-105.
    • (1992) Science , vol.256 , pp. 102-105
    • Sidransky, D.1    Tokino, T.2    Hamilton, S.R.3
  • 5
    • 84965905669 scopus 로고
    • Principles of screening for disease
    • Wilson JM. Principles of screening for disease. Proc. R. Soc. Med. 1971; 64; 1255-1256.
    • (1971) Proc. R. Soc. Med. , vol.64 , pp. 1255-1256
    • Wilson, J.M.1
  • 6
    • 0027373764 scopus 로고
    • Programmed cell death and the control of cell survival: Lessons from the nervous sytem
    • Raff MC, Barres BA, Burne JF, Coles HS, Ishizaki Y, Jacobson MD. Programmed cell death and the control of cell survival: lessons from the nervous sytem. Science 1993; 262; 695-700.
    • (1993) Science , vol.262 , pp. 695-700
    • Raff, M.C.1    Barres, B.A.2    Burne, J.F.3    Coles, H.S.4    Ishizaki, Y.5    Jacobson, M.D.6
  • 7
    • 0028362879 scopus 로고
    • Cell death genes: Drosophila enters the field
    • Raff MC. Cell death genes: Drosophila enters the field. Science 1994; 264; 668-669.
    • (1994) Science , vol.264 , pp. 668-669
    • Raff, M.C.1
  • 8
    • 0023875870 scopus 로고
    • Differential influence of adjacent normal cells on the prolifertion of mammalian cells transformed by the viral oncogenes myc, ras and src
    • Bignami M, Rosa S, La-Rocca SA, Falcone G, Tato F. Differential influence of adjacent normal cells on the prolifertion of mammalian cells transformed by the viral oncogenes myc, ras and src. Oncogene 1988; 2; 509-514.
    • (1988) Oncogene , vol.2 , pp. 509-514
    • Bignami, M.1    Rosa, S.2    La-Rocca, S.A.3    Falcone, G.4    Tato, F.5
  • 9
    • 0026504147 scopus 로고
    • Social controls on cell survival and cell death
    • Raff MC. Social controls on cell survival and cell death. Nature 1992; 356; 397-400.
    • (1992) Nature , vol.356 , pp. 397-400
    • Raff, M.C.1
  • 10
    • 0027753280 scopus 로고
    • Cancer, catenins, and cuticle pattern: A complex connection
    • Peifer M. Cancer, catenins, and cuticle pattern: a complex connection. Science 1993; 262; 1667-1668.
    • (1993) Science , vol.262 , pp. 1667-1668
    • Peifer, M.1
  • 11
    • 0029007855 scopus 로고
    • The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa B activation
    • Hsu H, Xiong J, Goeddel DV. The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa B activation. Cell 1995; 81; 495-504.
    • (1995) Cell , vol.81 , pp. 495-504
    • Hsu, H.1    Xiong, J.2    Goeddel, D.V.3
  • 12
    • 0029066697 scopus 로고
    • Contenders in FasL/TNF death signaling
    • Cleveland JL, Ihle JN. Contenders in FasL/TNF death signaling. Cell 1995; 81; 479-482.
    • (1995) Cell , vol.81 , pp. 479-482
    • Cleveland, J.L.1    Ihle, J.N.2
  • 13
    • 0025765985 scopus 로고
    • The role of the arginine-glycine-aspartic acid-directed cellular binding to type I collagen and rat mesenchymal cells in colorectal tumour differentiation
    • Del-Buono R, Pignatelli M, Bodmer WF, Wright NA. The role of the arginine-glycine-aspartic acid-directed cellular binding to type I collagen and rat mesenchymal cells in colorectal tumour differentiation. Differentiation 1991; 46; 97-103.
    • (1991) Differentiation , vol.46 , pp. 97-103
    • Del-Buono, R.1    Pignatelli, M.2    Bodmer, W.F.3    Wright, N.A.4
  • 14
    • 0024399684 scopus 로고
    • Oncogenes, antioncogenes, and the molecular bases of multistep carcinogenesis
    • Weinberg RA. Oncogenes, antioncogenes, and the molecular bases of multistep carcinogenesis. Cancer Res. 1989; 49; 3713-3721.
    • (1989) Cancer Res. , vol.49 , pp. 3713-3721
    • Weinberg, R.A.1
  • 15
    • 0020520516 scopus 로고
    • Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes
    • Land H, Parada LF, Weinberg RA. Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes. Nature 1983; 304; 596-602.
    • (1983) Nature , vol.304 , pp. 596-602
    • Land, H.1    Parada, L.F.2    Weinberg, R.A.3
  • 16
    • 0021673319 scopus 로고
    • Cooperation between gene encoding p53 tumour antigen and ras in cellular transformation
    • Parada LF, Land H, Weinberg RH, Wolf D, Rotter V. Cooperation between gene encoding p53 tumour antigen and ras in cellular transformation. Nature 1984; 312; 649-651.
    • (1984) Nature , vol.312 , pp. 649-651
    • Parada, L.F.1    Land, H.2    Weinberg, R.H.3    Wolf, D.4    Rotter, V.5
  • 17
    • 0026636158 scopus 로고
    • Ras-induced hyperplasia occurs with mutation of p53, but activated ras and myc together can induce carcinoma without p53 mutation
    • Lu X, Park SH, Thompson TC, Lane DP. Ras-induced hyperplasia occurs with mutation of p53, but activated ras and myc together can induce carcinoma without p53 mutation. Cell 1992; 70; 153-161.
    • (1992) Cell , vol.70 , pp. 153-161
    • Lu, X.1    Park, S.H.2    Thompson, T.C.3    Lane, D.P.4
  • 18
    • 37949049850 scopus 로고
    • The evolution of cancer of the colon and rectum
    • Muto T, Bussey HJ, Morson BC. The evolution of cancer of the colon and rectum. Cancer 1975; 36; 2251-2270.
    • (1975) Cancer , vol.36 , pp. 2251-2270
    • Muto, T.1    Bussey, H.J.2    Morson, B.C.3
  • 19
    • 0025312728 scopus 로고
    • A genetic model for colorectal tumourigenesis
    • Fearon ER, Vogelstein B. A genetic model for colorectal tumourigenesis. Cell 1990; 61; 759-767.
    • (1990) Cell , vol.61 , pp. 759-767
    • Fearon, E.R.1    Vogelstein, B.2
  • 20
    • 0026630266 scopus 로고
    • APC mutations occur early during colorectal tumorigenesis
    • Powell SM, Zilz N, Beazer-Barclay Y et al. APC mutations occur early during colorectal tumorigenesis. Nature 1992; 359; 235-237.
    • (1992) Nature , vol.359 , pp. 235-237
    • Powell, S.M.1    Zilz, N.2    Beazer-Barclay, Y.3
  • 21
    • 0027521850 scopus 로고
    • The role of the adenomatous polyposis coli (APC) gene in human cancers
    • Nakamura Y. The role of the adenomatous polyposis coli (APC) gene in human cancers. Adv. Cancer Res. 1993; 62; 65-87.
    • (1993) Adv. Cancer Res. , vol.62 , pp. 65-87
    • Nakamura, Y.1
  • 22
    • 0026726952 scopus 로고
    • Molecular analysis of APC mutations in familial adenomatous polyposis and sporadic colon carcinomas
    • Cottrell S, Bicknell D, Kaklamanis L, Bodmer WF. Molecular analysis of APC mutations in familial adenomatous polyposis and sporadic colon carcinomas. Lancet 1992; 340; 626-630.
    • (1992) Lancet , vol.340 , pp. 626-630
    • Cottrell, S.1    Bicknell, D.2    Kaklamanis, L.3    Bodmer, W.F.4
  • 24
    • 0028954815 scopus 로고
    • Embryonic axis induction by the armadillo repeat domain of beta-catenin: Evidence for intracellular signaling
    • Funayama N, Fagotto F, McCrea P, Gumbiner BM. Embryonic axis induction by the armadillo repeat domain of beta-catenin: evidence for intracellular signaling. J. Cell Biol. 1995; 128; 959-968.
    • (1995) J. Cell Biol. , vol.128 , pp. 959-968
    • Funayama, N.1    Fagotto, F.2    McCrea, P.3    Gumbiner, B.M.4
  • 26
    • 0028839835 scopus 로고
    • Alterations in DNA methylation may play a variety of roles in carcinogenesis
    • Counts J, Goodman J. Alterations in DNA methylation may play a variety of roles in carcinogenesis. Cell 1995; 83; 13-15.
    • (1995) Cell , vol.83 , pp. 13-15
    • Counts, J.1    Goodman, J.2
  • 27
    • 0023898932 scopus 로고
    • The ras gene family and human carcinogenesis
    • Bos JL. The ras gene family and human carcinogenesis. Mutat. Res. 1988; 195; 255-271.
    • (1988) Mutat. Res. , vol.195 , pp. 255-271
    • Bos, J.L.1
  • 28
    • 0026498381 scopus 로고
    • Polymerase chain reaction microanalysis of tumors from stained histological slides
    • Whetsell L, Maw G, Nadon N, Ringer DP, Schaefer FV. Polymerase chain reaction microanalysis of tumors from stained histological slides. Oncogene 1992; 7; 2355-2361.
    • (1992) Oncogene , vol.7 , pp. 2355-2361
    • Whetsell, L.1    Maw, G.2    Nadon, N.3    Ringer, D.P.4    Schaefer, F.V.5
  • 29
    • 0028302286 scopus 로고
    • K-ras mutations and p53 alterations in neoplastic and nonneoplastic lesions associated with longstanding ulcerative colitis
    • Chaubert P, Benhattar J, Saraga E, Costa J. K-ras mutations and p53 alterations in neoplastic and nonneoplastic lesions associated with longstanding ulcerative colitis. Am. J. Pathol. 1994; 144; 767-775.
    • (1994) Am. J. Pathol. , vol.144 , pp. 767-775
    • Chaubert, P.1    Benhattar, J.2    Saraga, E.3    Costa, J.4
  • 30
    • 0028931739 scopus 로고
    • Mutant K-ras in apparently normal muscosa of colorectal cancer patients. Its potential as a biomarker of colorectal tumorigenesis
    • Minamoto T, Yamashita N, Ochiai A et al. Mutant K-ras in apparently normal muscosa of colorectal cancer patients. Its potential as a biomarker of colorectal tumorigenesis. Cancer 1995; 75 (suppl.); 1520-1526.
    • (1995) Cancer , vol.75 , Issue.SUPPL. , pp. 1520-1526
    • Minamoto, T.1    Yamashita, N.2    Ochiai, A.3
  • 31
    • 0027973077 scopus 로고
    • Molecular determinants of dysplasia in colorectal lesions
    • Jen J, Powell SM, Papadopoulos N et al. Molecular determinants of dysplasia in colorectal lesions. Cancer Res. 1994; 54; 5523-5526.
    • (1994) Cancer Res. , vol.54 , pp. 5523-5526
    • Jen, J.1    Powell, S.M.2    Papadopoulos, N.3
  • 33
    • 0028157851 scopus 로고
    • Increased fibronectin-receptor expression in colon carcinoma-derived HT 29 cells decreases tumorigenicity in nude mice
    • Stallmach A, von-Lampe B, Orzechowski HD, Matthes H, Riecken EO. Increased fibronectin-receptor expression in colon carcinoma-derived HT 29 cells decreases tumorigenicity in nude mice. Gastroenterology 1994; 106; 19-27.
    • (1994) Gastroenterology , vol.106 , pp. 19-27
    • Stallmach, A.1    Von-Lampe, B.2    Orzechowski, H.D.3    Matthes, H.4    Riecken, E.O.5
  • 34
    • 0026658606 scopus 로고
    • Morphoregulatory activities of E-cadherin and beta-1 integrins in colorectal tumour cells
    • Pignatelli M, Liu D, Nasim MM, Stamp GW, Hirano S, Takeichi M. Morphoregulatory activities of E-cadherin and beta-1 integrins in colorectal tumour cells. Br. J. Cancer 1992; 66; 629-634.
    • (1992) Br. J. Cancer , vol.66 , pp. 629-634
    • Pignatelli, M.1    Liu, D.2    Nasim, M.M.3    Stamp, G.W.4    Hirano, S.5    Takeichi, M.6
  • 35
    • 0027257193 scopus 로고
    • Models of colorectal tumour differentiation
    • Pignatelli M. Models of colorectal tumour differentiation. Cancer Surv. 1993; 16; 3-13.
    • (1993) Cancer Surv. , vol.16 , pp. 3-13
    • Pignatelli, M.1
  • 36
    • 0027745259 scopus 로고
    • E-cadherin expression in colorectal cancer. An immunocytochemical and in situ hybridization study
    • Dorudi S, Sheffield JP, Poulsom R, Northover JM, Hart IR. E-cadherin expression in colorectal cancer. An immunocytochemical and in situ hybridization study. Am. J. Pathol. 1993; 142; 981-986.
    • (1993) Am. J. Pathol. , vol.142 , pp. 981-986
    • Dorudi, S.1    Sheffield, J.P.2    Poulsom, R.3    Northover, J.M.4    Hart, I.R.5
  • 38
    • 0028071555 scopus 로고
    • Mutations in the p53 tumor suppressor gene: Clues to cancer etiology and molecular pathogenesis
    • Greenblatt MS, Bennett WP, Hollstein M, Harris CC. Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis. Cancer Res 1994; 54; 4855-4878.
    • (1994) Cancer Res , vol.54 , pp. 4855-4878
    • Greenblatt, M.S.1    Bennett, W.P.2    Hollstein, M.3    Harris, C.C.4
  • 39
    • 0027109075 scopus 로고
    • Cancer. p53, guardian of the genome
    • Lane DP. Cancer. p53, guardian of the genome. Nature 1992; 358; 15-16.
    • (1992) Nature , vol.358 , pp. 15-16
    • Lane, D.P.1
  • 40
    • 0028294605 scopus 로고
    • WAF1/CIP1 is induced in p53-mediated G1 arrest and apoptosis
    • el-Deiry WS, Harper JW, O'Connor PM et al. WAF1/CIP1 is induced in p53-mediated G1 arrest and apoptosis. Cancer Res. 1994; 54; 1169-1174.
    • (1994) Cancer Res. , vol.54 , pp. 1169-1174
    • El-Deiry, W.S.1    Harper, J.W.2    O'Connor, P.M.3
  • 41
    • 0028275667 scopus 로고
    • Deletion analysis of chromosome 8p in sporadic colorectal adenomas
    • Cunningham C, Dunlop MG, Bird CC, Wyllie AH. Deletion analysis of chromosome 8p in sporadic colorectal adenomas. Br. J. Cancer 1994; 70; 18-20.
    • (1994) Br. J. Cancer , vol.70 , pp. 18-20
    • Cunningham, C.1    Dunlop, M.G.2    Bird, C.C.3    Wyllie, A.H.4
  • 43
    • 0026344557 scopus 로고
    • Relationships between umpk and pgd activities and deletions of chromosome 1p in colorectal cancers
    • Bravard A, Luccioni C, Muleris M, Lefrancois DBD. Relationships between umpk and pgd activities and deletions of chromosome 1p in colorectal cancers. Cancer Gent. Cytogenet. 1991; 56; 45-56.
    • (1991) Cancer Gent. Cytogenet. , vol.56 , pp. 45-56
    • Bravard, A.1    Luccioni, C.2    Muleris, M.3    Lefrancois, D.B.D.4
  • 44
    • 0027500221 scopus 로고
    • Cytogenetic aberrations in colorectal adenocarcinomas and their correlation with clinicopathological features
    • Bardi G, Johansson B, Pandis N et al. Cytogenetic aberrations in colorectal adenocarcinomas and their correlation with clinicopathological features. Cancer 1993; 71; 306-314.
    • (1993) Cancer , vol.71 , pp. 306-314
    • Bardi, G.1    Johansson, B.2    Pandis, N.3
  • 45
    • 0027245846 scopus 로고
    • Chromosome 7q deletions: Observations on 13 malignant tumors
    • Atkin NB, Baker MC. Chromosome 7q deletions: observations on 13 malignant tumors. Cancer Genet. Cytocgenet. 1993; 67; 123-125.
    • (1993) Cancer Genet. Cytocgenet. , vol.67 , pp. 123-125
    • Atkin, N.B.1    Baker, M.C.2
  • 46
    • 0028929987 scopus 로고
    • Frequent loss of heterozygosity in human primary squamous-cell and colon carcinomas at 7q32.I-evidence for a broad range tumor-suppressor gene
    • Zenklusen J, Thompson J, Kleinszanto A, Conti C. Frequent loss of heterozygosity in human primary squamous-cell and colon carcinomas at 7q32.I-evidence for a broad range tumor-suppressor gene. Cancer Res. 1995; 55; 1347-1350.
    • (1995) Cancer Res. , vol.55 , pp. 1347-1350
    • Zenklusen, J.1    Thompson, J.2    Kleinszanto, A.3    Conti, C.4
  • 47
    • 0027419340 scopus 로고
    • Frequent loss of heterozygosity on chromosome-14 occurs in advanced colorectal carcinomas
    • Young J, Leggett B, Ward M et al. Frequent loss of heterozygosity on chromosome-14 occurs in advanced colorectal carcinomas. Oncogene 1993; 8; 671-675.
    • (1993) Oncogene , vol.8 , pp. 671-675
    • Young, J.1    Leggett, B.2    Ward, M.3
  • 48
    • 0028301964 scopus 로고
    • Prognostic-significance of the loss of heterozygosity of nm23-h1 and p53 genes in human colorectal carcinomas
    • Campo E, Miquel R, Jares P et al. Prognostic-significance of the loss of heterozygosity of nm23-h1 and p53 genes in human colorectal carcinomas. Cancer 1994; 73; 2913-2921.
    • (1994) Cancer , vol.73 , pp. 2913-2921
    • Campo, E.1    Miquel, R.2    Jares, P.3
  • 49
    • 0029016477 scopus 로고
    • Colorectal carcinomas show frequent allelic loss on the long arm of chromosome-17 with evidence for a specific target region
    • Leggett B, Young J, Buttenshaw R et al. Colorectal carcinomas show frequent allelic loss on the long arm of chromosome-17 with evidence for a specific target region. B. J. Cancer 1995; 71; 1070-1073.
    • (1995) B. J. Cancer , vol.71 , pp. 1070-1073
    • Leggett, B.1    Young, J.2    Buttenshaw, R.3
  • 50
    • 0028988358 scopus 로고
    • 17q allele loss is associated with lymph-node metastasis in locally aggressive human colorectal-cancer
    • Purdie C, Piris J, Bird C, Wyllie A. 17q allele loss is associated with lymph-node metastasis in locally aggressive human colorectal-cancer. J. Pathol. 1995; 175; 297-302.
    • (1995) J. Pathol. , vol.175 , pp. 297-302
    • Purdie, C.1    Piris, J.2    Bird, C.3    Wyllie, A.4
  • 51
    • 0028293408 scopus 로고
    • Molecular genetics for clinical management of colorectal carcinoma. 17p. 18q. and 22q loss of heterozygosity and decreased DCC expression are correlated with the metastic potential
    • Iino H, Fukayama M, Maeda Y et al. Molecular genetics for clinical management of colorectal carcinoma. 17p. 18q. and 22q loss of heterozygosity and decreased DCC expression are correlated with the metastic potential. Cancer 1994; 73; 1324-1331.
    • (1994) Cancer , vol.73 , pp. 1324-1331
    • Iino, H.1    Fukayama, M.2    Maeda, Y.3
  • 52
    • 0028936598 scopus 로고
    • Frequent loss of heterozygosity at telomeric loci on 22q in sporadic colorectal cancers
    • Yana I, Kurahashi H, Nakamori S et al. Frequent loss of heterozygosity at telomeric loci on 22q in sporadic colorectal cancers. Int. J. Cancer 1995; 60; 174-177.
    • (1995) Int. J. Cancer , vol.60 , pp. 174-177
    • Yana, I.1    Kurahashi, H.2    Nakamori, S.3
  • 53
    • 0027171533 scopus 로고
    • Suppression of tumorigenicity in human colon-carcinoma cells by introduction of normal chromosome 1p36 region
    • Tanaka K, Yanoshita R, Konishi M et al. Suppression of tumorigenicity in human colon-carcinoma cells by introduction of normal chromosome 1p36 region. Oncogene 1993; 8; 2253-2258.
    • (1993) Oncogene , vol.8 , pp. 2253-2258
    • Tanaka, K.1    Yanoshita, R.2    Konishi, M.3
  • 54
    • 0024333328 scopus 로고
    • Expression of c-myc oncogene in colorectal polyps as a biological marker for monitoring malignant potential
    • Imaseki H, Hayashi H, Taira M et al. Expression of c-myc oncogene in colorectal polyps as a biological marker for monitoring malignant potential. Cancer 1989; 64; 704-709.
    • (1989) Cancer , vol.64 , pp. 704-709
    • Imaseki, H.1    Hayashi, H.2    Taira, M.3
  • 55
    • 0025100403 scopus 로고
    • Alteration and enhanced expression of the c-myc oncogene in human colorectal carcinomas
    • Matsumura T, Dohi K, Takanashi A, Ito H, Tahara E. Alteration and enhanced expression of the c-myc oncogene in human colorectal carcinomas. Pathol. Res. Pract. 1990; 186; 205-211.
    • (1990) Pathol. Res. Pract. , vol.186 , pp. 205-211
    • Matsumura, T.1    Dohi, K.2    Takanashi, A.3    Ito, H.4    Tahara, E.5
  • 56
    • 0026591443 scopus 로고
    • High c-myc protein expression in benign colorectal lesions correlates with the degree of dysplasia
    • Pavelic ZP, Pavelic L, Kuvelkar R, Gapany SR. High c-myc protein expression in benign colorectal lesions correlates with the degree of dysplasia. Anticancer Res. 1992; 12; 171-175.
    • (1992) Anticancer Res. , vol.12 , pp. 171-175
    • Pavelic, Z.P.1    Pavelic, L.2    Kuvelkar, R.3    Gapany, S.R.4
  • 57
    • 0024354721 scopus 로고
    • Evidence that the familial adenomatous polyposis gene is involved in a subset of colon cancers with a complementable defect in c-myc regulation
    • Krisman MD, Scott JK, Astrin SM. Evidence that the familial adenomatous polyposis gene is involved in a subset of colon cancers with a complementable defect in c-myc regulation. Proc. Natal. Acad. Sci. USA 1989; 86; 4264-4268.
    • (1989) Proc. Natal. Acad. Sci. USA , vol.86 , pp. 4264-4268
    • Krisman, M.D.1    Scott, J.K.2    Astrin, S.M.3
  • 59
    • 0028040019 scopus 로고
    • Bcl-2 and the regulation of programmed cell death
    • Reed JC. Bcl-2 and the regulation of programmed cell death. J. Cell Biol. 1994; 124; 1-6.
    • (1994) J. Cell Biol. , vol.124 , pp. 1-6
    • Reed, J.C.1
  • 60
    • 0026688162 scopus 로고
    • Apoptotic cell death induced by c-myc is inhibited by bcl-2
    • Bissonnette RP, Echeverri F, Mahboubi A, Green DR. Apoptotic cell death induced by c-myc is inhibited by bcl-2. Nature 1992; 359; 552-554.
    • (1992) Nature , vol.359 , pp. 552-554
    • Bissonnette, R.P.1    Echeverri, F.2    Mahboubi, A.3    Green, D.R.4
  • 61
    • 0028109983 scopus 로고
    • BCL-2 expression in human colorectal adenomas and carcinomas
    • Hauge A, Moorghen M, Hicks D, Chapman M, Paraskeva C. BCL-2 expression in human colorectal adenomas and carcinomas. Oncogene 1994; 9; 3367-3370.
    • (1994) Oncogene , vol.9 , pp. 3367-3370
    • Hauge, A.1    Moorghen, M.2    Hicks, D.3    Chapman, M.4    Paraskeva, C.5
  • 62
    • 0028814213 scopus 로고
    • The bcl-2 protooncogene and the gastrointestinal epithelial tumour progression model
    • Bronner MP, Culin C, Reed JC, Furth EE. The bcl-2 protooncogene and the gastrointestinal epithelial tumour progression model. Am. J. Pathol. 1995; 146; 20-26.
    • (1995) Am. J. Pathol. , vol.146 , pp. 20-26
    • Bronner, M.P.1    Culin, C.2    Reed, J.C.3    Furth, E.E.4
  • 63
    • 0029351569 scopus 로고
    • Microsatellite instability and Hereditary Non-Polyposis Colon Cancer
    • Peltomaki P. Microsatellite instability and Hereditary Non-Polyposis Colon Cancer. J. Pathol. 1995; 176; 329-330.
    • (1995) J. Pathol. , vol.176 , pp. 329-330
    • Peltomaki, P.1
  • 64
    • 0028034537 scopus 로고
    • The tumour spectrum in INPCC
    • Watson P, Lynch H. The tumour spectrum in INPCC. Anticancer Res. 1994; 14; 1635-1640.
    • (1994) Anticancer Res. , vol.14 , pp. 1635-1640
    • Watson, P.1    Lynch, H.2
  • 65
    • 0027158031 scopus 로고
    • Clues to the pathogenesis of familial colorectal cancer
    • Aaltonen LA, Peltomaki P, Leach FS et al. Clues to the pathogenesis of familial colorectal cancer. Science 1993; 260; 812-816.
    • (1993) Science , vol.260 , pp. 812-816
    • Aaltonen, L.A.1    Peltomaki, P.2    Leach, F.S.3
  • 67
    • 0027314411 scopus 로고
    • Microsatellite instability in cancer of the proximal colon
    • Thibodeau SN, Bren G, Schaid D. Microsatellite instability in cancer of the proximal colon. Science 1993; 260; 816-819.
    • (1993) Science , vol.260 , pp. 816-819
    • Thibodeau, S.N.1    Bren, G.2    Schaid, D.3
  • 68
    • 0027742295 scopus 로고
    • The human mutator gene homolog MSH2 and its associaton with hereditary nonpolyposis colon cancer
    • Fishel R, Lescoe MK, Rao MR et al. The human mutator gene homolog MSH2 and its associaton with hereditary nonpolyposis colon cancer. Cell 1993; 75; 1027-1038.
    • (1993) Cell , vol.75 , pp. 1027-1038
    • Fishel, R.1    Lescoe, M.K.2    Rao, M.R.3
  • 69
    • 0027263363 scopus 로고
    • Genetic mapping of a locus predisposing to human colorectal cancer
    • Peltomaki P, Aaltonen LA, Sistonen P et al. Genetic mapping of a locus predisposing to human colorectal cancer. Science 1993; 260; 810-812.
    • (1993) Science , vol.260 , pp. 810-812
    • Peltomaki, P.1    Aaltonen, L.A.2    Sistonen, P.3
  • 70
    • 0027145633 scopus 로고
    • Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer
    • Leach FS, Nicolaides NC, Papadopoulos N et al. Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer. Cell 1993; 75; 1215-1225.
    • (1993) Cell , vol.75 , pp. 1215-1225
    • Leach, F.S.1    Nicolaides, N.C.2    Papadopoulos, N.3
  • 71
    • 0028221943 scopus 로고
    • Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancer
    • Bronner CE, Baker SM, Morrison PT et al. Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancer. Nature 1994; 368; 258-61.
    • (1994) Nature , vol.368 , pp. 258-261
    • Bronner, C.E.1    Baker, S.M.2    Morrison, P.T.3
  • 72
    • 0027933070 scopus 로고
    • Mutations of two PMS homologues in hereditary nonpolypesis colon cancer
    • Nicolaides NC, Papadopoulos N, Liu B et al. Mutations of two PMS homologues in hereditary nonpolypesis colon cancer. Nature 1994; 371; 75-80.
    • (1994) Nature , vol.371 , pp. 75-80
    • Nicolaides, N.C.1    Papadopoulos, N.2    Liu, B.3
  • 73
    • 0028595722 scopus 로고
    • Binding of mismatched microsatellite DNA sequences by the human MSH2 protein
    • Fishel R, Ewel A, Lee S, Lescoe MK, Griffith J. Binding of mismatched microsatellite DNA sequences by the human MSH2 protein. Science 1994; 266; 1403-1405.
    • (1994) Science , vol.266 , pp. 1403-1405
    • Fishel, R.1    Ewel, A.2    Lee, S.3    Lescoe, M.K.4    Griffith, J.5
  • 74
    • 0027205395 scopus 로고
    • Nucleotide repeats. Slippery DNA and diseases
    • Kunkel TA. Nucleotide repeats. Slippery DNA and diseases. Nature 1993; 365; 207-208.
    • (1993) Nature , vol.365 , pp. 207-208
    • Kunkel, T.A.1
  • 75
    • 0026355962 scopus 로고
    • Mechanisms and biological effects of mismatch repair
    • Modrich P. Mechanisms and biological effects of mismatch repair. Ann. Rev. Genet. 1991; 25; 229-253.
    • (1991) Ann. Rev. Genet. , vol.25 , pp. 229-253
    • Modrich, P.1
  • 76
    • 0029042130 scopus 로고
    • Identification of mismatch repir genes and their role in the development of cancer
    • Fishel R, Kolodner RD. Identification of mismatch repir genes and their role in the development of cancer. Curr. Opin. Genet. Dev. 1995; 5; 382-395.
    • (1995) Curr. Opin. Genet. Dev. , vol.5 , pp. 382-395
    • Fishel, R.1    Kolodner, R.D.2
  • 77
    • 0027750908 scopus 로고
    • Carcinogenesis. Missing mismatch repair
    • Radman M, Wagner R. Carcinogenesis. Missing mismatch repair. Nature 1993; 366; 722.
    • (1993) Nature , vol.366 , pp. 722
    • Radman, M.1    Wagner, R.2
  • 78
    • 0027137935 scopus 로고
    • Hypermutability and mismatch repair deficiency in RER+ tumor cells
    • Parsons R, Li GM, Longley MJ et al. Hypermutability and mismatch repair deficiency in RER+ tumor cells. Cell 1993; 75; 1227-1236.
    • (1993) Cell , vol.75 , pp. 1227-1236
    • Parsons, R.1    Li, G.M.2    Longley, M.J.3
  • 79
    • 0028887597 scopus 로고
    • Increased mutation rale at the hprt locus accompanies microsatellite instability in colon cancer
    • Eshleman JR, Lang EZ, Bowerfind GK et al. Increased mutation rale at the hprt locus accompanies microsatellite instability in colon cancer. Oncogene 1995; 10; 33-37.
    • (1995) Oncogene , vol.10 , pp. 33-37
    • Eshleman, J.R.1    Lang, E.Z.2    Bowerfind, G.K.3
  • 80
    • 0028226295 scopus 로고
    • Replication errors in benign and malignant tumors from hereditary nonpolyposis colorectal cancer patients
    • Aaltonen LA, Peltomaki P, Mecklin JP et al. Replication errors in benign and malignant tumors from hereditary nonpolyposis colorectal cancer patients. Cancer Res. 1994; 54; 1645-1648.
    • (1994) Cancer Res. , vol.54 , pp. 1645-1648
    • Aaltonen, L.A.1    Peltomaki, P.2    Mecklin, J.P.3
  • 81
    • 0028859671 scopus 로고
    • Mismatch repair gene defects in sporadic colorectal cancers with microsatellite instability
    • Liu B, Nicolaides NC, Markowitz S et al. Mismatch repair gene defects in sporadic colorectal cancers with microsatellite instability. Nat. Genet. 1995; 9; 48-55.
    • (1995) Nat. Genet. , vol.9 , pp. 48-55
    • Liu, B.1    Nicolaides, N.C.2    Markowitz, S.3
  • 82
    • 0028141683 scopus 로고
    • Hereditary non-polyposis colon cancer - Morphologies. genes and mutations
    • Jass JR, Stewart SM, Stewart J, Lane MR. Hereditary non-polyposis colon cancer - morphologies. genes and mutations. Mutat Res. 1994; 310; 125-133.
    • (1994) Mutat Res. , vol.310 , pp. 125-133
    • Jass, J.R.1    Stewart, S.M.2    Stewart, J.3    Lane, M.R.4
  • 83
    • 0029089040 scopus 로고
    • Colorectal adenomas in surgical specimens from subjects with hereditary non-polyposis colorectal cancer
    • Jass JR. Colorectal adenomas in surgical specimens from subjects with hereditary non-polyposis colorectal cancer. Histopathology 1995; 27; 263-267.
    • (1995) Histopathology , vol.27 , pp. 263-267
    • Jass, J.R.1
  • 84
    • 0028276666 scopus 로고
    • Clinical and pathological characteristics of sporadic colorectal carcinomas with DNA replication errors in microsatellite sequences
    • Kim H, Jen J, Vogelstein B, Hamilton SR. Clinical and pathological characteristics of sporadic colorectal carcinomas with DNA replication errors in microsatellite sequences. Am. J. Pathol. 1994; 145; 148-156.
    • (1994) Am. J. Pathol. , vol.145 , pp. 148-156
    • Kim, H.1    Jen, J.2    Vogelstein, B.3    Hamilton, S.R.4
  • 85
    • 0029066689 scopus 로고
    • Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability
    • Markowitz S, Wang J, Myeroff L et al. Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability. Science 1995; 268; 1336-1338.
    • (1995) Science , vol.268 , pp. 1336-1338
    • Markowitz, S.1    Wang, J.2    Myeroff, L.3
  • 86
    • 0026758347 scopus 로고
    • Inflammatory bowel disease and cancer
    • Levin B. Inflammatory bowel disease and cancer. Cancer 1992; 70; 1313-1316.
    • (1992) Cancer , vol.70 , pp. 1313-1316
    • Levin, B.1
  • 87
    • 0025979693 scopus 로고
    • Colorectal cancer in ulcerative colitis. Influence of anatomical extent and age at onset on colitis-cancer interval
    • Sugita A, Sachar DB, Bodian C, Ribeiro MB, Aufses A Jr., Greenstein AJ. Colorectal cancer in ulcerative colitis. Influence of anatomical extent and age at onset on colitis-cancer interval. Gut 1991; 32; 167-169.
    • (1991) Gut , vol.32 , pp. 167-169
    • Sugita, A.1    Sachar, D.B.2    Bodian, C.3    Ribeiro, M.B.4    Aufses Jr., A.5    Greenstein, A.J.6
  • 88
    • 0023856775 scopus 로고
    • Colorectal cancer in ulcerative colitis: A cohort study of primary referrals from three centres
    • Gyde S, Prior P, Allan R et al. Colorectal cancer in ulcerative colitis: a cohort study of primary referrals from three centres. Gut 1988; 29; 206-217.
    • (1988) Gut , vol.29 , pp. 206-217
    • Gyde, S.1    Prior, P.2    Allan, R.3
  • 90
    • 0027967342 scopus 로고
    • Clinicopathological characteristics of colorectal carcinoma complicating ulcerative colitis
    • Connell W, Talbot IC, Harpaz N et al. Clinicopathological characteristics of colorectal carcinoma complicating ulcerative colitis. Gut 1994; 35; 1419-1423.
    • (1994) Gut , vol.35 , pp. 1419-1423
    • Connell, W.1    Talbot, I.C.2    Harpaz, N.3
  • 91
    • 0028305575 scopus 로고
    • Risk factors for colorectal cancer in patients with ulcerative colitis: A case control study
    • Pinczowski D, Ekbom A, Baron J, Yuen J, Adami H-O. Risk factors for colorectal cancer in patients with ulcerative colitis: a case control study. Gastroenterology 1994; 107; 117-120.
    • (1994) Gastroenterology , vol.107 , pp. 117-120
    • Pinczowski, D.1    Ekbom, A.2    Baron, J.3    Yuen, J.4    Adami, H.-O.5
  • 92
    • 0021017589 scopus 로고
    • Dysplasia in inflammatory bowel disease: Standardised classification with provisional clinical applications
    • Riddell R, Goldman H, Ransohoff D et al. Dysplasia in inflammatory bowel disease: standardised classification with provisional clinical applications. Hum. Pathol. 1993; 14; 931-968.
    • (1993) Hum. Pathol. , vol.14 , pp. 931-968
    • Riddell, R.1    Goldman, H.2    Ransohoff, D.3
  • 93
    • 0023214021 scopus 로고
    • Colonic pericryptal fibroblast sheath cells: Characterisation of cell type with a new monoclonal antibody
    • Richman PI, Tilly R, Jass JR, Bodmer WF. Colonic pericryptal fibroblast sheath cells: characterisation of cell type with a new monoclonal antibody. J. Clin. Pathol. 1987; 40; 593-600.
    • (1987) J. Clin. Pathol. , vol.40 , pp. 593-600
    • Richman, P.I.1    Tilly, R.2    Jass, J.R.3    Bodmer, W.F.4
  • 94
    • 0027238642 scopus 로고
    • Significance of pericryptal fibroblasts in colorectal epithelial tumours: A special reference to the histologic features and growth patterns
    • Yao T, Tsuneyoshi M. Significance of pericryptal fibroblasts in colorectal epithelial tumours: a special reference to the histologic features and growth patterns. Hum. Pathol. 1993; 24; 525-533.
    • (1993) Hum. Pathol. , vol.24 , pp. 525-533
    • Yao, T.1    Tsuneyoshi, M.2
  • 95
    • 0028921585 scopus 로고
    • Common occurrence of APC and K-ras mutation in the spectrum of colitis-associated neoplasias
    • Redston M, Papadopoulos N, Caldas C, Kinzler K, Kern S. Common occurrence of APC and K-ras mutation in the spectrum of colitis-associated neoplasias. Gastroenterology 1995; 108; 383-392.
    • (1995) Gastroenterology , vol.108 , pp. 383-392
    • Redston, M.1    Papadopoulos, N.2    Caldas, C.3    Kinzler, K.4    Kern, S.5
  • 96
    • 0028979727 scopus 로고
    • Adenomatous polyposis coli gene mutations in ulcerative colitis-associated dysplasias and cancers versus sporadic colon neoplasms
    • Tarmin L, Yin J, Harpaz N, Kozam M et al. Adenomatous polyposis coli gene mutations in ulcerative colitis-associated dysplasias and cancers versus sporadic colon neoplasms. Cancer Res. 1995; 55; 2035-2038.
    • (1995) Cancer Res. , vol.55 , pp. 2035-2038
    • Tarmin, L.1    Yin, J.2    Harpaz, N.3    Kozam, M.4
  • 97
    • 84966163814 scopus 로고
    • C-ki-ras gene mutations in dysplasia and carcinomas complicating ulcerative colitis
    • Bell SM, Kelly SA, Hoyle JA et al. C-ki-ras gene mutations in dysplasia and carcinomas complicating ulcerative colitis. Br. J. Cancer 1991; 64; 174-178.
    • (1991) Br. J. Cancer , vol.64 , pp. 174-178
    • Bell, S.M.1    Kelly, S.A.2    Hoyle, J.A.3
  • 98
    • 0025303624 scopus 로고
    • Activation of c-Ki-ras in human gastrointestinal dysplasias determined by direct sequencing of polymerase chain reaction products
    • Meltzer SJ, Mane SM, Wood PK et al. Activation of c-Ki-ras in human gastrointestinal dysplasias determined by direct sequencing of polymerase chain reaction products. Cancer Res. 1990; 50; 3627-3630.
    • (1990) Cancer Res. , vol.50 , pp. 3627-3630
    • Meltzer, S.J.1    Mane, S.M.2    Wood, P.K.3
  • 101
    • 0023706935 scopus 로고
    • Dysplasia and deoxyribonucleic acid aneuploidy in the assessment of precancerous changes in chronic ulcerative colitis. Observer variation and correlations
    • Melville DM, Jass JR, Shepherd NA et al. Dysplasia and deoxyribonucleic acid aneuploidy in the assessment of precancerous changes in chronic ulcerative colitis. Observer variation and correlations. Gastroenterology 1988; 95; 668-675.
    • (1988) Gastroenterology , vol.95 , pp. 668-675
    • Melville, D.M.1    Jass, J.R.2    Shepherd, N.A.3
  • 102
    • 0026605115 scopus 로고
    • DNA aneuploidy in ulcerative colitis: Reproducibility, topographic distribution, and relation to dysplasia
    • Lofberg R, Brostrom O, Karlen P, Ost A, Tribukait B. DNA aneuploidy in ulcerative colitis: reproducibility, topographic distribution, and relation to dysplasia. Gastroenterology 1992; 102; 1149-1154.
    • (1992) Gastroenterology , vol.102 , pp. 1149-1154
    • Lofberg, R.1    Brostrom, O.2    Karlen, P.3    Ost, A.4    Tribukait, B.5
  • 103
    • 0026663080 scopus 로고
    • DNA aneuploidy in colonic biopsies predicts future development of dysplasia in ulcerative colitis
    • Rubin CE, Haggit RC, Burmer GC et al. DNA aneuploidy in colonic biopsies predicts future development of dysplasia in ulcerative colitis. Gastroenterology 1992; 103; 1611-1620.
    • (1992) Gastroenterology , vol.103 , pp. 1611-1620
    • Rubin, C.E.1    Haggit, R.C.2    Burmer, G.C.3
  • 104
    • 0028295305 scopus 로고
    • DNA aneuploidy and histologic dysplasia in long-standing ulcerative colitis. A 10-year follow-up study
    • Befrits R, Hammarberg C, Rubio C, Jaramillo E, Tribukait B. DNA aneuploidy and histologic dysplasia in long-standing ulcerative colitis. A 10-year follow-up study. Dis. Colon Rectum 1994; 37; 313-319.
    • (1994) Dis. Colon Rectum , vol.37 , pp. 313-319
    • Befrits, R.1    Hammarberg, C.2    Rubio, C.3    Jaramillo, E.4    Tribukait, B.5
  • 105
    • 0027194679 scopus 로고
    • p53 Point mutations in dysplastic and cancerous ulcerative colitis lesions
    • Yin J, Harpaz N, Tong Y et al. p53 Point mutations in dysplastic and cancerous ulcerative colitis lesions. Gastroenterology 1993; 104; 1633-1639.
    • (1993) Gastroenterology , vol.104 , pp. 1633-1639
    • Yin, J.1    Harpaz, N.2    Tong, Y.3
  • 106
    • 0028122352 scopus 로고
    • Mutations in the p53 gene: An early marker of neoplastic progression in ulcerative colitis
    • Brentall TA, Crispin DA, Rabinovitch PS et al. Mutations in the p53 gene: An early marker of neoplastic progression in ulcerative colitis. Gastroenterology 1994; 107; 369-378.
    • (1994) Gastroenterology , vol.107 , pp. 369-378
    • Brentall, T.A.1    Crispin, D.A.2    Rabinovitch, P.S.3
  • 107
    • 0023835918 scopus 로고
    • Minute cancers arising de-nove in the human large intestine
    • Kuramoto S, Oohara T. Minute cancers arising de-nove in the human large intestine. Cancer 1988; 61; 829-834.
    • (1988) Cancer , vol.61 , pp. 829-834
    • Kuramoto, S.1    Oohara, T.2
  • 108
    • 0028861574 scopus 로고
    • Small depressed cancer of the large bowel: Report of three cases
    • Yokota T, Sugihara K, Yokoyama T et al. Small depressed cancer of the large bowel: report of three cases. Am. J. Gastroenterol. 1995; 90; 134-136.
    • (1995) Am. J. Gastroenterol. , vol.90 , pp. 134-136
    • Yokota, T.1    Sugihara, K.2    Yokoyama, T.3
  • 109
    • 0028270711 scopus 로고
    • Colorectal counterpart of gastric depressed adenoma. A comparison with flat and polypoid adenomas with special reference to the development of pericryptal fibroblasts
    • Yao T, Tada S, Tsuneyoshi M. Colorectal counterpart of gastric depressed adenoma. A comparison with flat and polypoid adenomas with special reference to the development of pericryptal fibroblasts. Am. J. Surg. Pathol 1994; 18; 559-568.
    • (1994) Am. J. Surg. Pathol , vol.18 , pp. 559-568
    • Yao, T.1    Tada, S.2    Tsuneyoshi, M.3
  • 110
    • 0028854853 scopus 로고
    • Polypoid growth and K-ras codon 12 mutation in colorectal cancer
    • Yamagata S, Muto T, Uchida Y et al. Polypoid growth and K-ras codon 12 mutation in colorectal cancer. Cancer 1995; 75; 935-957.
    • (1995) Cancer , vol.75 , pp. 935-957
    • Yamagata, S.1    Muto, T.2    Uchida, Y.3
  • 111
    • 0028000987 scopus 로고
    • Comparative clinicopathological and immunohistochemical study of ras and p53 in flat and polypoid type colorectal tumours
    • Yukawa M, Fujimori T, Maeda S, Tabuchi M, Nagasako K. Comparative clinicopathological and immunohistochemical study of ras and p53 in flat and polypoid type colorectal tumours. Gut 1994; 35; 1258-1261.
    • (1994) Gut , vol.35 , pp. 1258-1261
    • Yukawa, M.1    Fujimori, T.2    Maeda, S.3    Tabuchi, M.4    Nagasako, K.5
  • 113
    • 0027995407 scopus 로고
    • A clinicopathologic study of small flat colorectal carcinoma
    • Tada S, Yao T, Iida M, Koga H, Hizawa K, Fujishima M. A clinicopathologic study of small flat colorectal carcinoma. Cancer 1994; 74, 2430-2435.
    • (1994) Cancer , vol.74 , pp. 2430-2435
    • Tada, S.1    Yao, T.2    Iida, M.3    Koga, H.4    Hizawa, K.5    Fujishima, M.6
  • 114
    • 0028951471 scopus 로고
    • How do colorectal cancers develop?
    • Kuramoto S, Oohara T. How do colorectal cancers develop? Cancer 1995; 75 (suppl.); 1534-1538.
    • (1995) Cancer , vol.75 , Issue.SUPPL. , pp. 1534-1538
    • Kuramoto, S.1    Oohara, T.2


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