ActA and human zyxin harbour Arp2/3-independent actin-polymerization activity

Nature Cell Biology

Volumn 3, Issue 8, 2001, Pages 699-707

  Fradelizi, Julie ^a   Noireaux, Vincent ^b,c   Plastino, Julie ^b   Menichi, Bernadette ^a   Louvard, Daniel ^a   Sykes, Cécile ^b   Golsteyn, Roy M ^a,d   Friederich, Evelyne ^a,e,f  

^a INSTITUT CURIE   (France)

^b INSTITUT CURIE   (France)

^c ROCKEFELLER UNIVERSITY   (United States)

^d INSTITUT DE RECHERCHES SERVIER   (France)

^e LUXEMBOURG INSTITUTE OF HEALTH   (Luxembourg)

^f UNIVERSITY OF LUXEMBOURG   (Luxembourg)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; BACTERIAL PROTEIN; CYTOSKELETON PROTEIN; F ACTIN; GENE PRODUCT; MEMBRANE PROTEIN; PROTEIN ACTA; UNCLASSIFIED DRUG; VASODILATOR STIMULATED PHOSPHOPROTEIN; WISKOTT ALDRICH SYNDROME PROTEIN; ZYXIN;

ACTIN POLYMERIZATION; ANIMAL CELL; ARTICLE; CELL ACTIVITY; COMPLEX FORMATION; CONTROLLED STUDY; CYTOSKELETON; HUMAN; HUMAN CELL; IN VITRO STUDY; LISTERIA MONOCYTOGENES; MITOCHONDRION; MOLECULAR BIOLOGY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DETERMINATION; PROTEIN INTERACTION; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; STRUCTURE ANALYSIS;

ANIMALIA; BACTERIA (MICROORGANISMS); LISTERIA MONOCYTOGENES;

EID: 0034906978     PISSN: 14657392     EISSN: None     Source Type: Journal    
DOI: 10.1038/35087009     Document Type: Article

References (45)

1. The mammalian Arp2/3 complex localizes to regions of lamellipodial protrusion and is composed of conserved subunits
2. Relationship between Arp2/3 complex and the barbed ends of actin filaments at the leading edge of carcinoma cells after epidermal growth factor stimulation
3. Identification of a new protein localized at sites of cell-substrate adhesion
4. Actin filaments and the growth, movement, and spread of the intracellular bacterial parasite, Listeria monocytogenes
5. Scar, a WASp-related protein, activates nucleation of actin filaments by the Arp2/3 complex
6. The interaction between N-Wasp and the Arp2/3 complex links Cdc42-dependent signals to actin assembly
7. The interaction of Arp2/3 complex with actin: Nucleation, high affinity pointed end capping, and formation of branching networks of filaments
8. Arp2/3 complex and actin depolymerizing factor/cofilin in dendritic organization and treadmilling of actin filament array in lamellipodia
9. Actin filament organization in the fish keratocyte lamellipodium
10. A novel bacterial virulence gene in Listeria monocytogenes required for host cell microfilament interaction with homology to the proline-rich region of vinculin
11. L. monocytogenes-induced actin assembly requires the actA gene product, a surface protein
12. Structural and functional similarities between the human cytoskeletal protein zyxin and the ActA protein of Listeria monocytogenes
13. Purification and characterization of zyxin, an 82,000-Dalton component of adherens junctions
14. Zyxin: Zinc fingers at sites of cell adhesion
15. Molecular characterization of human zyxin
16. A zyxin-related protein whose synthesis is reduced in virally transformed fibroblasts
17. LPP, the preferred fusion partner gene of HMGIC in lipomas, is a novel member of the LIM protein gene family
18. The human TRIP6 gene encodes a LIM domain protein and maps to chromosome 7q22, a region associated with tumorigenesis
19. A novel proline-rich motif present in ActA of Listeria monocytogenes and cytoskeletal proteins is the ligand for the EVH1 domain, a protein module present in the Ena/VASP family
20. Characterization of the interaction between zyxin and Ena/VASP family of proteins
21. The amino-terminal part of ActA is critical for the actin-based motility of Listeria monocytogenes, the central proline-rich region acts as a stimulator
22. The tandem repeat domain in the Listeria monocytogenes ActA protein controls the rate of actin-based motility, the percentage of moving bacteria, and the localization of vasodilator-stimulated phosphoprotein and profilin
23. Reconstitution of actin-based motility of Listeria and Shigella using pure proteins
24. Inducible recruitment of Cdc42 or WASP to a cell-surface receptor triggers actin polymerization and filopodium formation
25. The Arp2/3 complex is essential for the actin-based motility of Listeria monocytogenes
26. An α-actinin binding site of zyxin is essential for subcellular zyxin localization and α-actinin recruitment
27. Motility of ActA protein-coated microspheres driven by actin polymerization
28. Growing an actin gel on spherical surfaces
29. Actin polymerization is induced by Arp2/3 protein complex at the surface of Listeria monocytogenes
30. Identification of two regions in the amino terminal domain of ActA involved in the actin comet tail formation by Listeria monocytogenes
31. Cooperative symmetry-breaking by actin polymerization in a model for cell motility
32. Organization and structure of actin filament bundles in Listeria infected cells
33. The isolated comet tail pseudopodium of Listeria monocytogenes: A tail of two actin filament populations, long and axial and short and random
34. Direct observation of dendretic actin filament networks nucleated by Arp2/3 complex and WASP/Scar proteins
35. Spatial control of actin filament assembly: Lessons from Listeria
36. Molecular dissection of zyxin function reveals its involvement in cell motility
37. Role of proteins of the Ena-VASP family in actin-based motility of Listeria monocytogenes
38. Actin polymerizability is influenced by profilin, a low molecular weight protein in non-muscle cells
39. The proline-rich focal adhesion and microfilament protein VASP is a ligand for profilins
40. Purification of a cortical complex containing two unconventional actins from Acanthamoeba by affinity chromatography on profilin agarose
41. Regulation of actin polymerization by Arp2/3 complex and WASp/Scar proteins
42. Quantitative measurement of proteins by western blotting with Cy5 coupled secondary antibodies
43. Mobility of microinjected rhodamine actin within living chicken gizzard cells determined by fluorescence photobleaching recovery
44. Targeting of Listeria monocytogenes ActA protein to the plasma membrane as a tool to dissect both actin-based cell morphogenesis and ActA function