Active matrilysin (MMP-7) in human pterygia: Potential role in angiogenesis

Investigative Ophthalmology and Visual Science

Volumn 42, Issue 9, 2001, Pages 1963-1968

  Di Girolamo, N ^a   Coroneo, M T ^a   Wakefield, D ^a  

^a UNIVERSITY OF NEW SOUTH WALES   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

MATRILYSIN;

ANGIOGENESIS; ARTICLE; CELLULAR DISTRIBUTION; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; ENZYME ACTIVATION; ENZYME ASSAY; ENZYME RELEASE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; PATHOGENESIS; PRIORITY JOURNAL; PTERYGIUM;

ADULT; ANTIBODIES, MONOCLONAL; ANTIBODY SPECIFICITY; BLOTTING, WESTERN; CONJUNCTIVA; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME ACTIVATION; FEMALE; HUMANS; IMMUNOENZYME TECHNIQUES; MALE; MATRIX METALLOPROTEINASE 7; MIDDLE AGED; NEOVASCULARIZATION, PATHOLOGIC; ORGAN CULTURE TECHNIQUES; PTERYGIUM;

EID: 0034899073     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (38)

1. Immunohistochemical evidence that human pterygia originate from an invasion of vimentin-expressing altered limbal epithelial basal cells
2. The pathogenesis of pterygia
3. Pterygium as an early indicator of ultraviolet insolation: A hypothesis
4. Apoptosis and apoptosis related gene expression in normal conjunctiva and pterygium
5. p53 expression and relation to human papillomavirus infection in pingueculae, pterygia, and limbal tumors
6. A hypothesis on the pathogenesis of pterygium
7. Capillaries in the epithelium of pterygium
8. Expression of MMPs and TIMPs in human pterygia and cultured pterygium epithelial cells
9. Differential expression of matrix metalloproteinases and their tissue inhibitors at the advancing pterygium head
10. Regulation of collagenase, stromelysin, and urokinase-type plasminogen activator in primary pterygium body fibroblasts by inflammatory cytokines
11. Pterygia pathogenesis: Corneal invasion by matrix metalloproteinase (MMP) expressing altered limbal basal stem cells and activation of fibroblasts
12. Overexpression of collagenase (MMP-1) and stromelysin (MMP-3) by cultured pterygium head fibroblasts
13. Matrix metalloproteinases
14. Matrix metalloproteinases and their inhibitors in tumour growth and invasion
15. Mechanisms of tissue destruction and cellular activation in rheumatoid arthritis
16. Localization of TIMP-1, TIMP-2, TIMP-3, gelatinase A and gelatinase B in pathological human corneas
17. Increased expression of matrix metalloproteinases in vivo in scleritis tissue and in vitro in cultured human scleral fibroblasts
18. Increased matrix metalloproteinases in the aqueous humor of patients and experimental animals with uveitis
19. Tissue inhibitors of metalloproteinases: Structure, regulation and biological functions
20. Production of metalloproteinase-7 (matrilysin) by human myeloma cells and its potential involvement in metalloproteinase-2 activation
21. Matrilysin: An epithelial matrix metalloproteinase with potentially novel functions
22. Matrix metalloproteinase-7-dependent release of tumor necrosis factor-α in a model of herniated discs resorption
23. Microscopic localization of active proteases by in situ zymography: Detection of matrix metalloproteinase activity in vascular tissue
24. Matrilysin expression and function in airway epithelium
25. Matrix metalloproteinase matrilysin is constitutively expressed by epithelial cells in human exocrine epithelium
26. The metalloproteinase matrilysin is preferentially expressed by epithelial cells in a tissue-restricted pattern in the mouse
27. Evidence for increased activated metalloproteinase 2 (MMP2a) expression associated with human prostate cancer progression
28. Human matrix metalloproteinase-9: Activation by limited trypsin treatment and generation of monoclonal antibodies specific for the activated form
29. Expression of degradative enzymes and protease inhibitors in corneas with keratoconus
30. In situ zymographic localisation of type II collagen degrading activity in osteoarthritic human articular cartilage
31. Detection of collagenase-induced damage of collagen by 9A4, a monoclonal C-terminal neoepitope antibody
32. Immunolocalization and gene expression of matrilysin during corneal wound healing
33. Suppression of matrilysin inhibits colon cancer cell invasion in vitro
34. Matrilysin-specific antisense oligonucleotide inhibits liver metastasis of human colon cancer cells in a nude mouse model
35. Expression of matrix metalloproteinase-7 in choroidal neovascular membranes in age-related macular degeneration
36. Expression of matrilysin in vascular endothelial cells adjacent to matrilysin-producing tumors
37. Heparin sulphate proteoglycans as extracellular docking molecules for matrilysin (matrix metalloproteinase 7)
38. Accumulation of matrilysin (MMP-7) and macrophage metalloelastase (MMP-12) in actinic damage