In situ zymographic localisation of type II collagen degrading activity in osteoarthritic human articular cartilage

Annals of the Rheumatic Diseases

Volumn 58, Issue 6, 1999, Pages 357-365

  Freemont, A J ^a   Byers, R J ^a   Taiwo, Y O ^b   Hoyland, J A ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b PROCTER AND GAMBLE PHARMACEUTICALS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN TYPE 2; COLLAGENASE; SULFUR 35; TISSUE INHIBITOR OF METALLOPROTEINASE;

ADULT; AGED; ARTICLE; ARTICULAR CARTILAGE; CARTILAGE CELL; CARTILAGE DEGENERATION; COLLAGEN DEGRADATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME LOCALIZATION; FEMALE; HUMAN; HUMAN TISSUE; IN SITU HYBRIDIZATION; JOINT PROSTHESIS; MALE; OSTEOARTHRITIS; PRIORITY JOURNAL; ZYMOGRAPHY;

EID: 0033001430     PISSN: 00034967     EISSN: None     Source Type: Journal    
DOI: 10.1136/ard.58.6.357     Document Type: Article

References (42)

1. 1 Cawston TE, Billington C. Metalloproteinases in the rheumatic diseases. J Pathol 1996;180:115-17.
2. 2 Pelletier JP, Martel-Pelletier J, Malemud CJ. Proteoglycans from experimental osteoarthritic cartilage: degradation by neutral metalloproteinases. J. Rheumatol 1987;14:113-15.
3. 3 McCachren SS. Expression of metalloproteinases and metalloproteinase inhibitor in human arthritic synovium. Arthritis Rheum 1991;34:1085-93.
4. 4 Case JP, Lafyatis R, Remmers EF, Kumkumian GK, Wilder RL. Transin/stromelysin expression in rheumatoid synovium: a transformation-associated metalloproteinase secreted by phenotypically invasive synoviocytes. Am J Pathol 1989;135:1055-64.
5. 5 Cooper C. Osteoarthritis: epidemiology, In: Klippel JH, Dieppe P, eds. Rheumatology. London: A Mosby, 1994: section 7, subsection 3.
6. 6 Dean DD, Martel-Pelletier J, Pelletier JP, Howell DS, Woessner JF jr. Evidence for metalloproteinase and metalloproteinase inhibitor imbalance in human osteoarthritic cartilage. J Clin Invest 1989;84:678-85.
7. 7 Pelletier J P, Mineau F, Faure MP, Martel-Pelletier J. Imbalance between the mechanisms of activation and inhibition of metalloproteases in the early lesions of experimental osteoarthritis. Arthritis Rheum 1990;33:1466-76.
8. 8 Martel-Pelletier J, McCollum R, Fujimoto N, Obata K, Cloutier JM, Pelletier JP. Excess of metalloproteinases over tissue inhibitor of metalloproteinase may contribute to cartilage degradation in osteoarthritis and rheumatoid arthritis. Lab Invest 1994;70:807-15.
9. 9 Martel-Pelletier J, Pelletier JP. Neutral proteases in human osteoarthritic synovium: quantification and characterisation. J Rheumatol 1987;14:38-40.
10. 10 Woessner JF Jr, Gunja-Smith Z. Role of metalloproteinases in human osteoarthritis. J Rheumatol 1991;18:99-101.
11. 11 Wolfe GC, MacNaul KL, Buechel FF, McDonnell J, Hoerrner LA, Lark MW, et al. Differential in vivo expression of collagenase messenger RNA in synovium and cartilage. Arthritis Rheum 1993;36:1540-7.
12. 12 Sapolsky A, Malemud C, Sheff M. The proteoglycanase from human cartilage and cultured rabbit chondrocytes and its relation to osteoarthritis. J Rheumatol 1987;14: 33-5.
13. 13 Dean DD, Azzo W, Martel-Pelletier J, Pelletier JP, Woessner JF jr. Levels of metalloproteases and tissue inhibitor of metalloproteases in human osteoarthritic cartilage. J Rheumatol 1987;14:43-4.
14. 14 Martel-Pelletier J, Zafarullah M, Kodama S, Pelletier JP. In-vitro effects of interleukin 1 on the synthesis of metalloproteases, TIMP, plasminogen activators and inhibitors in human cartilage. J Rheumatol Suppl 1991;27:80-4
15. 15 Lefebvre V, Peeters-Joris C, Vaes G. Production of gelatin-degrading matrix metalloproteinase ("type IV collagenases") and inhibitors by articular chondrocytes during their dedifferentiation by serial subcultures and under stimulation by interleukin-1 and tumour necrosis factor alpha. Biochim Biophys Acta 1991;1094:8-18
16. 16 Mehraban F, Kuo SY, Riera H, Chang C, Moskowitz RW. Prostromelysin and procollagenase genes are differentially up-regulated in chondrocytes from the knees of rabbits with experimental osteoarthritis. Arthritis Rheum 1994;37: 1189-97
17. 17 Freemont AJ, Hampson V, Tilman R, Goupille P, Taiwo Y, Hoyland JA. Gene expression of matrix metalloproteinases 1,3 and 9 by chondrocytes in osteoarthritic human knee articular cartilage is zone and grade specific. Ann Rheum Dis 1997;56:542-9
18. 18 Martel-Pelletier J, Pelletier J-P. Wanted - the collagenase responsible for the destruction of the collagen network in human cartilage! Br J Rheumatol 1996;35:818-20.
19. 19 Freije JMP, Diez-Itza, Balbin M, Sanchez L, Blasco R, Toliva J, et al. Molecular cloning and expression of collagenase-3, a novel human matrix metalloproteinase produced by breast carcinomas. J Biol Chem 1994;269: 16766-73
20. 20 Knauper V, Lopez-Otin c, Smith B, Knight G, Murphy G. Biochemical characterisation of human collagenase-3. J Biol Chem 1996;271:1544-50.
21. 21 Reboul P, Pelletier JP, Tardif G, Cloutier JM, MartelPelletier J. The new collagenase, collagenase-3, is expressed and synthesised by human chondrocytes but not synoviocytes. A role in osteoarthritis. J Clin Invest 1996;97:2011-19.
22. 22 Mitchell PG, Magna HA, Reeves LM, Lopresti-Morrow LL, Yocum SA, Rosner PJ, et al. Cloning, expression and type II collagenolytic activity of matrix metalloproteinase-13 from human osteoarthritic cartilage. J Clin Invest 1996;97:761-8.
23. 23 Shlopov BV, Lie W-R, Mainardi CL, Cole AA, Chubinskaya S, Hasty KA. Osteoarthritic lesions: Involvement of three different collagenases. Arthritis Rheum 1997;40:2065-74.
24. 24 Marles PJ, Hoyland JA, Parkinson R, Freemont AJ. Demonstration of variation in chondrocyte activity in different zones of articular cartilage - an assessment of the value of in-situ hybridisation. . Int J Exp Pathol 1991:72;171-82.
25. 25 Hoyland J, Freemont A Investigation of a quantitative post-hybridization signal amplification system for mRNA-oligodeoxyribonucleotide in-situ hybridization. J Pathol 1991;164:51-8.
26. 26 Walsh L, Freemont AJ, Hoyland JA. The effect of tissue decalcification on mRNA retention with bone for in-situ hybridisation studies. Int J Exp Pathol 1993;74:237-41.
27. 27 Hoyland JA, Freemont A, Investigation of a quantitative post-hybridisation signal amplification system for mRNA-oligodeoxyribonucleotide in-situ hybridisation. J Pathol 1991;164:51-8.
28. 28 Galis ZS, Sukhova GK, Libby P. Microscopic localisation of active proteases by in situ zymography: detection of matrix metalloproteinase active in vascular tissue. FASEB J 1995; 9:974-80.
29. 29 Pelletier JP, Roughley PJ, DiBattista JA, McCollum R, Martel-Pelletier J. Are cytokines involved in osteoarthritic pathophysiology? Semin Arthritis Rheum 1991;20 (suppl 2)12-25.
30. 30 Mort JS, Dodge GR, Roughley PJ, Liu J, Finch SJ, DiPasquale G, et al. Direct evidence for active metalloproteinases mediating matrix degradation in interleukin 1-stimulated human articular curtilage. Matrix 1993;13: 95-102.
31. 31 Bunning R A, Richardson H J, Crawford A, Skjodt H, Hughes D, Evans DB, et al. The effect of interleukin-1 on connective tissue metabolism and its relevance to arthritis. Agents Actions 1986;18 (suppl):131-52.
32. 32 Shingu M, Isayama T, Naono T, Nobunaga, Nagai Y. The effects of cytokines on metalloproteinase inhibitors (TIMP) and collagenase production by human chondrocytes and TIMP production by synovial cells and endothelial cells. Clin Exp Immunol 1993;94:145-9.
33. 33 Buttle DJ, Bramwell H, Hollander AP. Proteolytic mechanisms of cartilage breakdown, a target for arthritis therapy? J Clin Paihol Mol Pathol 1995;48:M167-77.
34. 34 Hollander AP, Pidoux I, Reiner A, Rorabeck C, Bourne R, Poole AR. Damage to type II collagen in aging and osteoarthritis starts at the articular surface, originates around chondrocytes, and extends into the cartilage with progressive degeneration. J Clin Invest 1995;96: 2859-69.
35. 35 Vankemmelebeke M, Dekeyser PM, Hollander AP, Buttle DJ, Demeester J. Characterisation of the helical cleavages in type II collagen generated by matrixins. Biochem J 1998; 330:633-40.
36. 36 Panula HE, Hyttinen MM, Arokoski JPA, Langsjo TK, Pelttari A, Kiviranta I, et al. Articular cartilage superficial zone collagen birefringence reduced and cartilage thickness increased before surface fibrillation in experimental osteoarthritis. Ann Rheum Dis 1998;57:237-45.
37. 37 Stahle-Backdahl M, Sandstedt B, Bruce K, Lindahl A, Jiminez MG, Vega JA, et al. Collagenase-3 (MMP-13) is expressed during fetal ossification and re-exprossed in postnatal bone remodelling and in rheumatoid arthritis. Lab Invest 1997;76:717-28.
38. 38 Cazorla M, Hernandez L, Nadal A, Balbin M, Lopez JM, Viziso F, et al. Collagenase-3 expression is associated with advanced local invasion in human squamous cell carcinomas of the larynx. J.Pathol 1998;186:144-50.
39. 39 Moldovan F, Pelletier J-P, Hambor J, Cloutier J-M, Martel-Pelletier J. Collagenase-3 (matrix metalloprotease 13) is preferentially localised in the deep layer of human arthritic cartilage in situ: in vitro mimicking effect by transforming growth factor beta. Arthritis Rheum 1997;40:1653-61.
40. 40 Lindy O, Konttinen YT, Sorsa T, Ding Y, Santavirta S, Ceponis A, et al. Matrix metalloproteinase 13 (collagenase 3) in human rheumatoid synovium. Arthritis Rheum 1997; 40:1391-9.
41. 41 Billinghurst RC, Dahlberg L, Ionescu M, Reiner A, Bourne R, Rorabeck C, et al. Enhanced cleavage of type II collagen by collagenases in osteoarthritic articular cartilage. J Clin Invest 1997;99:1534-45.
42. 42 Wernicke D, Seyfert C, Hinzmann R, Gromnica-Ihle E. Cloning of collagenase 3 from the synovial membrane and its expression in rheumatoid arthritis and osteoarthritis. J Rheumatol 1996;23:590-5.