Matrilysin-specific antisense oligonucleotide inhibits liver metastasis of human colon cancer cells in a nude mouse model

International Journal of Cancer

Volumn 76, Issue 6, 1998, Pages 812-816

  Hasegawa, Satoshi ^a,b   Koshikawa, Naohiko ^a   Momiyama, Nobuyoshi ^b   Moriyama, Kayano ^a   Ichikawa, Yasushi ^b   Ishikanwa, Takashi ^b   Mitsuhashi, Masato ^c   Shimada, Hiroshi ^b   Miyazaki, Kaoru ^a  

^a YOKOHAMA CITY UNIVERSITY   (Japan)

^b YOKOHAMA CITY UNIVERSITY   (Japan)

^c Hitachi Chemical Research Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGODEOXYNUCLEOTIDE; MATRILYSIN;

ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL; CANCER PREVENTION; COLON CANCER; COLON CARCINOMA; HUMAN; HUMAN CELL; LIVER METASTASIS; MOUSE; NONHUMAN; NUDE MOUSE; PRIORITY JOURNAL;

AGED; ANIMALS; COLONIC NEOPLASMS; FEMALE; HUMANS; LIVER NEOPLASMS, EXPERIMENTAL; MATRIX METALLOPROTEINASE 7; METALLOENDOPEPTIDASES; MICE; MICE, INBRED BALB C; MICE, NUDE; OLIGONUCLEOTIDES, ANTISENSE;

EID: 0032503544     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0215(19980610)76:6<812::AID-IJC8>3.0.CO;2-0     Document Type: Article

References (31)

1. AGARWAL, B.B., SCHWARZ, L., HOGAN, M.E. and RANDO, R.F., Triple helix-forming oligodeoxyribonucleotides targeted to the human tumor necrosis factor (TNF) gene inhibit TNF production and the TNF-dependent growth of human glioblastoma tumor cells. Cancer Res., 56, 5156-5164 (1996).
2. AGRAWAL, S., TEMSAMANI, J. and TANG, Y.J., Pharmacokinetics, biodistribution, and stability of oligonucleotide phosphorothioates in mice. Proc. nat. Acad. Sci. (Wash.), 88, 7975-7599 (1991).
3. BASSET, P., BELLOCQ, J.P. and CHAMBON, P., A novel metalloproteinase gene specifically expressed in stromal cells of breast carcinomas. Nature (Lond.), 348, 699-704 (1990).
4. FINLAY, I.G. and MCARDLE, C.S., Effect of occult hepatic metastasis on survival after curative resection for colorectal carcinoma. Gastroenterology, 85, 596-600 (1983).
5. HEPPNER, K.J., MATRISIAN, L.M., JENSEN, R.A. and RODGERS, W.H., Expression of most matrix metalloproteinase family members in breast cancer represents a tumor-induced host response. Amer. J. Pathol., 149, 273-282 (1996).
6. ISHIKAWA, T., ICHIKAWA, Y. MITSUHASHI, M., MOMIYAMA, N., CHISHIMA, T., TANAKA, K., YAMAOKA, H., MIYAZAKI, K., NAGASHIMA, Y., AKITAYA, T. and SHIMADA, H., Matrilysin is associated with progression of colon tumor. Cancer Lett., 106, 5-10 (1996).
7. KOSHIKAWA, N., YASUMITSU, H., UMEDA, M. and MIYAZAKI, K., Multiple secretion of matrix serine proteinases by human gastric carcinoma cell lines. Cancer Res., 52, 5046-5053 (1992).
8. LEONETTI, D.A., LOZUPONE, F., VALENTINI, A., GEISER, T., ZON, G., CALABRETTERA, B., CITRO, G.C. and ZUPI, G., Antitumor effect of c-myc antisense phosphorothioate oligonucleotides on human melanoma cells in vitro and in mice. J. nat. Cancer Int., 88, 419-429 (1996).
9. MATRISIAN, L.M., The matrix-degrading metalloproteinases. Bioassays, 14, 455-463 (1992).
10. MCDONNEL, S., NAVRE, M., COFFEY, R.J., JR. and MATRISIAN, L.M., Expression and localization of the matrix metalloproteinase Pump-1 (MMP-7) in human gastric and colon carcinomas. Mol. Carcinogenesis, 4, 527-533 (1991).
11. MIYAZAKI, K., HATTORI, Y., UMENISHI, F., YASUMITSU, H. and UMEDA, M., Purification and characterization of extracellular matrix-degrading metalloproteinase, Matrin (PUMP-1), secreted from human rectal carcinoma cell line. Cancer Res., 50, 7758-7764 (1990).
12. MOMIYAMA, N., KOSHIKAWA, N., ISHIKAWA, T., ICHIKAWA, Y., HASEGAWA, S., NAGASHIMA, Y., MITSUHASHI, M., MIYAZAKI, K. and SHIMADA, H., Inhibitory effect of matrilysin antisense phosphorothioate oligonucleotides on human colon cancer cell invasion in vitro. Mol. Carcinogenesis (1998). (In press).
13. MORI, M., BARNARD, G.F., MIMORI, K., UEO, H., AKIYOSHI, T. and SUGIMACHI, K., Overexpression of matrix metalloproteinase-7 in human colon carcinomas. Cancer (Suppl.), 75, 1516-1519 (1995).
14. MULLER, D., QUANTIN, B., GESNEL, M.C., MILLON-COLLARD, R., ABECASSIS, J. and BREATHNACH, R., The collagenase gene family in humans consists of at least four members. Biochem J., 253, 187-192 (1989).
15. NAGASHIMA, Y., HASEGAWA, S., KOSHIKAWA, N., TAKI, A., ICHIKAWA, Y., KITAMURA, H., MISUGI, K., KIHIRA, Y., MATSUO, Y., YASUMITSU, H. and MIYAZAKI, K., Expression of matrilysin in vascular endothelial cell adjacent to matrilysin-producing tumor. Int. J. Cancer, 72, 1-5 (1997).
16. NARAYANAN, R. and AKHTAR, S., Antisense therapy. Curr. Opin. Oncol., 8, 509-515 (1990).
17. NEWELL, K., WITTY, J., RODGERS, W.H. and MATRISIAN, L.M., Expression and localization of the matrix metalloproteinases during colon carcinogenesis. Mol. Carcinogenesis. 10, 199-206 (1994).
18. NOGUCHI, P., WALLACE, R., JOHNSON, J., EARLEY, E.M., O'BRINEN, S., FERRONE, S., PELLEGRINO, M.A., MILSTIEN, J., NEEDY, C., BROWSE, W. and PETRICCINAI, J., Characterization of WiDr: a human colon carcinoma cell line. In Vitro. 15, 401-408 (1979).
19. PAJOUH, M.S., NAGLE, R.B., BREATHNACH, R., BRAWER, M.K. and BOWDEN, G.T., Expression of metalloproteinase genes in human prostate cancer. J. Cancer Res. Clin. Oncol., 117, 144-150 (1991).
20. PISANI, P., PARKIN, D.M. and FERLAY, J., Estimates of the worldwide mortality from eighteen major cancers in 1985. Implications for prevention and projections of future burden. Int. J. Cancer, 55, 891-903 (1993).
21. POWELL, W.C., KNOX, J.D., NAVRE, M., GROGAN, T.M., KITTELSON, J., NAGLE, R.B. and BOWDEN, G.T., Expression of the metalloproteinase matrilysin in DU-145 cells increases their invasive potential in severe combined immunodeficient mice. Cancer Res., 53, 417-422 (1993).
22. PYKE, C., PALFKIAER, M. and DANØ, K., Messenger RNA for two type collagenases is located in stromal cells in human colon cancer. Amer. J. Pathol., 142, 359-365 (1993).
23. SAIJO, Y., PERLAKY, L., WANG, H. and BUSCH, H., Pharmacokinetics, tissue distribution, and stability of antisense oligonucleotide phosphorothiate ISIS3466 in mice. Oncol. Res., 6, 243-249 (1994).
24. STEIN, C.A. and CHENG, Y.C., Antisense oligonucleotides as therapeutic reagents - is the bullet really magical? Science. 261, 1004-1012 (1993).
25. STETLER-STEVENSON, W.G., AZANAVOORIAN, S. and LIOTTA, L.A., Tumor cell interactions with the extracellular matrix during invasion and metastasis. Ann. Rev. Cell Biol., 9, 541-573 (1993).
26. WANG, X., FU, X., BROWN, D.P., CRIMMIN, J.M. and HOFFMAN, M.R., Matrix metalloproteinase inhibitor BB-94 (Batimastat) inhibits human colon tumor growth and spread in a patient-like orthotopic model in nude mice. Cancer Res., 54, 4726-4728 (1994).
27. WILSON, C.L., HEPPNER, K.J., LABOSKY, P.A., HOGAN, B.L.M. and MATRISIAN, L.M., Intestinal tumorigenesis is suppressed in mice lacking the metalloproteinase matrilysin. Proc. nat. Acad. Sci. (Wash.), 94, 1402-1407 (1997).
28. WILSON, C.L. and MATRISIAN, L.M., Matrilysin: An epithelial matrix metalloproteinase with potentially novel functions. Int. J. Biochem. Cell Biol., 28, 123-136 (1996).
29. WITTY, J.P., MCDONNELL, S., NEWELL, J.K., CANNON, P., NAVRE, M., TRESSLER, J.R. and MATRISIAN, L.M., Modulation of matrilysin levels in colon carcinoma cell lines affects tumorigenicity in vivo. Cancer Res., 54, 4805-4812 (1994).
30. YAMAMOTO, H., ITOH, F., HINODA, Y. and IMAI, K., Suppression of matrilysin inhibits colon cancer cell invasion in vitro. Int. J. Cancer, 61, 218-222 (1995).
31. YOSHIMOTO, M., ITOH, F., YAMAMOTO, H., HINODA, Y., IMAI, K. and YACHI, A., Expression of MMP-7 (pump-1) mRNA in human colorectal cancers. Int. J. Cancer, 54, 614-618 (1993).