Synthesis of N-arylrolipram derivatives - Potent and selective phosphodiesterase-IV inhibitors - by copper catalyzed lactam-aryl halide coupling

Heterocycles

Volumn 48, Issue 11, 1998, Pages 2225-2229

  Aebischcr, Esther ^a   Bacher, Edmond ^a   Joachim Demnitz, F W ^a,b   Keller, Thomas H ^a   Kurzmeyer, Miriam ^a   Ortiz, Marta L ^a   Pombo Villar, Esteban ^a   Weber, Hans Peter ^a  

^a NOVARTIS PHARMA AG   (Switzerland)

^b FEDERAL UNIVERSITY OF PERNAMBUCO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0004415521     PISSN: 03855414     EISSN: None     Source Type: Journal    
DOI: 10.3987/com-98-8322     Document Type: Article

References (6)

1. Praktikantin from the University of Santiago de Compostela, Spain, 1993.
2. C. Schudt, G. Dent, and K. F. Rabe, eds., 'Phosphodiesterase Inhibitors', Academic Press, London, 1996;
3. L. Sekut, D. Yarnall, S. A. Stimpson, L. S. Noel, R. Bateman-Fite, R. L. Clark, M. F. Brackeen, J. A. Menius, and K. M. Conolly, Clin. Exp. Immunol., 1995, 100, 126.
4. N. Sommer, P. A. Loeschmann, G. H. Northoff, M. Weller, A. Steinbrecher, J. P. Steinbach, R. Richtenfels, R. Meyermann, A. Reithmueller, A. Fontana, J. Dichgans, and R. Martin, Nature Med., 1995, 1, 244.
5. M. C. Marivet, J. J. Bourguignon, C. Lugnier, A. Mann, J. C. Stoclet, and C. G. Wermuth, J. Med. Chem., 1989, 32, 1450;
6. P. W. Baures, D. S. Eggleston, S. Drake, K. F. Erhard, L. B. Cieslinski, Th. J. Torphy, and S. B. Christensen, J. Med. Chem., 1993, 36, 3274.