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Biomolecular Engineering

Volumn 18, Issue 2, 2001, Pages 41-47

Engineering novel biocatalytic routes for production of semisynthetic opiate drugs

(3) Boonstra, Birgitte a Rathbone, Deborah A a Bruce, Neil C a

a UNIVERSITY OF CAMBRIDGE (United Kingdom)

Author keywords

Biotransformation; Cofactor regeneration; Hydromorphone; Recombinant biocatalyst; Semisynthetic opiates

Indexed keywords

ANALGESIC AGENT; ANTITUSSIVE AGENT; BACTERIAL ENZYME; CODEINE; DIAMORPHINE; DIHYDROCODEINE; DIHYDROMORPHINE; HYDROCODONE; HYDROMORPHONE; MORPHINE; MORPHINE DERIVATIVE; NALOXONE; NALTREXONE; OPIATE; OXYCODONE; OXYMORPHONE; THEBAINE;

BACTERIAL METABOLISM; BIOCATALYST; BIOTRANSFORMATION; CATALYST; CHEMICAL MODIFICATION; CONTROLLED STUDY; DRUG MANUFACTURE; DRUG SYNTHESIS; ESCHERICHIA COLI; GENETIC ENGINEERING; MICROORGANISM; NONHUMAN; PRIORITY JOURNAL; PSEUDOMONAS PUTIDA; RECOMBINANT DNA TECHNOLOGY; REVIEW;

EID: 0034887052 PISSN: 13890344 EISSN: None Source Type: Journal
DOI: 10.1016/S1389-0344(01)00084-3 Document Type: Article

Times cited : (35)

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