Potentiation of NMDA receptor function through somatostatin release: A possible mechanism for the cognition-enhancing activity of GABAB receptor antagonists

Neuropharmacology

Volumn 41, Issue 3, 2001, Pages 301-310

  Pittaluga, A ^a   Feligioni, M ^a   Ghersi, C ^a   Gemignani, A ^a   Raiteri, M ^a  

^a UNIVERSITY OF GENOA   (Italy)

Author keywords

Cognition enhancers; GABAB receptors; Kynurenate test; NMDA receptors; Somatostatin receptor subtypes; Somatostatin release

Indexed keywords

2 [1 (3 DIMETHYLAMINOPROPYL) 3 INDOLYL] 3 (3 INDOLYL)MALEIMIDE; 3 AMINOPROPYLBUTYLPHOSPHINIC ACID; 4 AMINOBUTYRIC ACID RECEPTOR BLOCKING AGENT; DEXTRO PHENYLALANYLPHENYLALANYLPHENYLALANYL DEXTRO TRYPTOPHYLLYSYLTHREONYLPHENYLALANYLTHREONINAMIDE; DEXTRO PHENYLALANYLPHENYLALANYLTYROSYL DEXTRO TRYPTOPHYLLYSYLVALYLPHENYLALANYL DEXTRO [3 (2 NAPHTHYL)ALANINAMIDE]; KYNURENIC ACID; L 362855; L 779976; L 796778; L 797591; L 803087; MERCAPTAMINE; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NORADRENALIN; PROTEIN KINASE C INHIBITOR; SOMATOSTATIN 14; SOMATOSTATIN DERIVATIVE; SOMATOSTATIN RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN; COGNITION; CONTROLLED STUDY; DEPLETION; DOSE RESPONSE; DRUG EFFECT; DRUG EXPOSURE; HIPPOCAMPUS; IMMUNOREACTIVITY; MALE; NERVE CELL; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; RAT; REGULATORY MECHANISM; SOMATOSTATIN RELEASE;

ANIMALS; COGNITION; EXCITATORY AMINO ACID ANTAGONISTS; GABA ANTAGONISTS; MALE; NOREPINEPHRINE; ORGANOPHOSPHORUS COMPOUNDS; PROTEIN KINASE C; RADIOIMMUNOASSAY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, AMPA; RECEPTORS, GABA-B; RECEPTORS, N-METHYL-D-ASPARTATE; RECEPTORS, SOMATOSTATIN; SINCALIDE; SOMATOSTATIN; SYNAPTOSOMES;

EID: 0034885530     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0028-3908(01)00066-1     Document Type: Article

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