Regulation of the leukotriene biosynthetic pathway

Clinical and Experimental Allergy Reviews

Volumn 1, Issue 2, 2001, Pages 128-132

  Peters Golden, M ^a  

^a UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; ARACHIDONATE 5 LIPOXYGENASE; ARACHIDONIC ACID; GLUCOCORTICOID; LEUKOTRIENE; LEUKOTRIENE A4 HYDROLASE; LEUKOTRIENE C4 SYNTHASE; PHOSPHOLIPASE A2;

ARACHIDONIC ACID METABOLISM; ASTHMA; BIOSYNTHESIS; CATALYSIS; CONFERENCE PAPER; ENZYME ACTIVITY; HUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; TRANSCRIPTION REGULATION;

EID: 0034883365     PISSN: 14729725     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1472-9725.2001.00023.x     Document Type: Conference Paper

References (20)

1. Intracellular compartmentalization of leukotriene biosynthesis
2. Hydrogen peroxide inhibits alveolar macrophage 5-lipoxygenase metabolism in association with depletion of ATP
3. 4 production
4. 2 is phosphorylated and activated by MAP kinase
5. 5-Lipoxygenase is phosphorylated by p38 kinase-dependent MAPKAP kinases
6. Adenosine a potent natural suppressor of arachidonic acid release and leukotriene biosynthesis in human neutrophils
7. 4 synthase
8. Regulation of expression of the 5-lipoxygenase pathway
9. Granulocyte/macrophage colony-stimulating factor stimulates the expression of the 5-lipoxygenase-activating protein (FLAP) in human neutrophils
10. Transforming growth factor β upregulates 5-lipoxygenase activity during myeloid maturation
11. IL-5 increases expression of 5-lipoxygenase-activating protein and translocates 5-lipoxygenase to the nucleus in human blood eosinophils
12. 3-deficient rats
13. GM-CSF regulates bleomycin-induced pulmonary fibrosis via a prostaglandin mechanism
14. Regulation of 5-lipoxygenase metabolism in mononuclear phagocytes by CD4 T lymphocytes
15. Granulocyte colony-stimulating factor administration to HIV-infected subjects augments reduced leukotriene synthesis and anticryptococcal activity in neutrophils
16. Naturally occurring mutations in the human 5-lipoxygenase gene promoter that modify transcription factor binding and reporter gene transcription
17. 4 in chemotactic peptide-stimulated human neutrophils
18. 4 secretion by fluticasone proprionate in exogenously activated human eosinophils
19. Regulation of 5-lipoxygenase activity in mononuclear phagocytes: Characterization of an endogenous cytosolic inhibitor
20. Glutathione peroxidase-1 but not -4 is involved in the regulation of cellular 5-lipoxygenase activity in monocytic cells