Regulation of expression of the 5-lipoxygenase pathway

Clinical Reviews in Allergy and Immunology

Volumn 17, Issue 1-2, 1999, Pages 43-58

  Bigby, Timothy D ^a  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5 HYDROPEROXY 6,8,11,14 ICOSATETRAENOIC ACID; ARACHIDONATE 5 LIPOXYGENASE; GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HYDROLASE; INTERLEUKIN 3; LEUKOTRIENE A4; LEUKOTRIENE B4; LEUKOTRIENE C4; LEUKOTRIENE C4 SYNTHASE; LEUKOTRIENE D4; LEUKOTRIENE E4; PEPTIDOLEUKOTRIENE; PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

ARACHIDONIC ACID METABOLISM; CHEMICAL REACTION; CYTOKINE PRODUCTION; CYTOKINE RELEASE; ENZYME ACTIVATION; ENZYME ACTIVITY; INFLAMMATORY CELL; LYMPHOCYTE ACTIVATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REACTION ANALYSIS; REGULATORY MECHANISM; REVIEW;

EID: 0032770244     PISSN: 10800549     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02737596     Document Type: Review

References (69)

1. Samuelsson B. Leukotrienes: Mediators of immediate hypersensitivity reactions and inflammation. Science 1983;220:568-575.
2. Rouzer CA, Samuelsson B. On the nature of the 5-lipoxygenase reaction in human leukocytes: Enzyme purification and requirement for multiple stimulatory factors. Proc Natl Acad Sci USA 1985;82:6040-6044.
3. Radmark O, Shimizu T, Jornvall H, Sannuelsson B. Leukotriene A4 hydrolase in human leukocytes. Purification and properties. J Biol Chem 1984;259:12,339-12,345.
4. 4 synthase: A homodimeric glutathione S-transferase composed of 18-kDa suburlits. Proc Natl Acad Sci USA 1993;90:2015-2019.
5. Henderson WR. The role of leukotrienes in inflammation. Ann Int Med 1994;121:684-697.
6. Kellaway CH, Trethewie ER. The liberation of a slow-reacting smooth muscle-stimulating substance in anaphylaxis. QJ Exp Physiol 1940;30:121-145.
7. Murphy RC, Hammarstrom S, Samuelsson B. Leukotriene C: A slow-reacting substance from murine mastocytoma cells. Proc Natl Acad Sci USA 1979;76:4275-4279.
8. Lewis RA, Austen KF, Soberman RJ. Leukotrienes and other products of the 5-lipoxygenase pathway. Biochemistry and relation to pathobiology in human diseases. N Engl J Med 1990;323:645-655.
9. 4 effects on human eosinophil and neutrophil motility in vitro. J Leuk Biol 1994;55:183-191.
10. Drazen JM, Austen KF, Lewis RA, Clark DA, Goto G, Marfat A, Corey EJ. Comparative airway and vascular actMties of leukotriene C-1 and D in vitro and in vivo. Proc Natl Acad Sci USA 1980;77:4354-4358.
11. Lam S, Chan H, Chan-Yeung M, Salari H. Release of leukotrienes in patients with bronchial asthma. J Allergy Clin Immunol 1988;81:711-717.
12. 4 in bronchoalveolar ravage fluid from atopic asthmatics after endobronchial allergen challenge. Am Rev Respir Dis 1990;142:112-119.
13. Wenzel SE, Westcott JY, Larsen GL. Bronchoalveolar lavage fluid mediator levels 5 minutes after allergen challenge in atopic subjects with asthma: Relationship to the development of late asthmatic responses. J Allergy Clin Immunol 1991;87:540-548.
14. 4 from the urine of patients with airway obstruction. Am Rev Respir Dis 1992;146:104-108.
15. 4 concentrations increase after aspirin challenge in aspirin-sensitive asthmatic subjects. Am Rev Respir Dis 1991;143:1025-1029.
16. Israel E, Dermakarian R, Rosenberg M, Sperling R, Taylor G, Rubin P, Drazen JM. The effects of a 5-lipoxygenase inhibitor on asthma induced by cold, dry air. N Engl J Med 1990;323:1740-1744.
17. 4 receptor antagonist. N Engl J Med 1990;323:1736-1739.
18. 4-induced bronchoconstriction in the human. Am Rev Respir Dis 1991;144:617-611.
19. Israel E, Rubin P, Kemp JP, Grossman J, Pierson W, Siegel SC, Tinkelman D, Murray JJ, Busse W, Segal AT. The effect of inhibition of 5-lipoxygenase by zileuton in mild-to-moderate asthma. Ann Intern Med 1993;119:1059-1066.
20. Drazen JM, Dahlen S-E, Lee T. Five Lipoxygenase Products in Asthma, Marcel Dekker, New York, 1998.
21. Dixon RA, Diehl RE, Opas E, Rands E, Vickers PJ, Evans JF, Gillard JW, Miller DK. Requirement of a 5-lipoxygenase-activating protein for leukotriene synthesis. Nature 1990;343:282-284.
22. 4 hydrolase. Proc Natl Acad Sci USA 1987;84:6677-6681.
23. Bigby TD, Holtzman MJ. Enhanced 5-lipoxygenase activity in lung macrophages compared to monocytes from normal subjects. J Immunol 1987;138:1546-1550.
24. Pueringer RJ, Bahns CC, Hunninghake GW. Alveolar macrophages have greater amounts of the enzyme 5-lipoxygenase than do monocytes. J Appl Physiol 1992;73:781-786.
25. Coffey MJ, Wilcoxen SE, Peters-Golden M. Increases in 5-lipoxygenase activating protein expression account for enhanced capacity for 5-lipoxygenase metabolism that accompanies differentiation of peripheral blood monocytes into alveolar macrophages. Am J Respir Cell Mol Biol 1994;11:153-158.
26. Bennett CF, Chiang MY, Monia BP, Crooke ST. Regulation of 5-lipoxygenase and 5-lipoxygenase-activating protein expression in HL-60 cells. Biochem J 1993;289:33-39.
27. Steinhilber D, Radmark O, Samuelsson B. Transforming growth factor β upregulates 5lipoxygenase activity during myeloid cell maturation. Proc Natl Acad Sci USA 1993;90:5984-5988.
28. Fair A, Pritchard KA. Oxidized low density lipoprotein increases U937 cell 5-lipoxygenase activity: Induction of 5-lipoxygenase activating protein. Biochem Biophys Res Com 1994;201:1014-1020.
29. Owen WF, Rothenberg ME, Silberstein DS, Gasson JC, Stevens RL, Austen KF, Soberman RJ. Regulation of human eosinophil viability, density, and function by granulocyte/macrophage colony-stimulating factor in the presence of 3T3 fibroblasts. J Exp Med 1987;166:129-141.
30. Rothenberg ME, Owen WF, Silberstein DS, Woods J, Soberman RJ, Austen KF, Stevens RL. Human eosinophils have prolonged survival, enhanced functional properties, and become hypodense when exposed to human interleukin 3. J Clin Invest 1988;81:1986-1992.
31. Silberstein DS, Owen WF, Gasson JC, Dipersio JF, Golde DW, Bina JC, Soberman R, Austen KF, David JR. Enhancement of human eosinophil cytoxicity and leukotriene synthesis by biosynthetic (recombinant) granulocyte-macrophage colony-stimulating factor. J Immunol 1986;137:3290-3294.
32. Roubin R, Elsas PP, Fiers W, Dessein AJ. Recombinant tumor necrosis factor (rTNF) enhances leukotriene biosynthesis in neutrophils and eosinophils stimulated with the Ca2+ ionophore A23187. Clin Exp Immunol 1987;70:484-490.
33. Dahinden CA, Zingg J, Maly FE, de Weck AL. Leukotriene production in human neutrophils primed by recombinant human granulocyte-macrophage colony-stimulating factor and stimulated with the complement component C5a and FMLP as second signals. J Exp Med 1988;167:1281-1294.
34. Krump E, Borgeat P. Kinetics of 5-lipoxygenase activation, arachidonic acid release, and leukotriene synthesis in human neutrophils: Effects of granulocyte-macrophage colony stimulating factor. Biochem B iophys Acta 1994;1213:135-139.
35. Palmantier R, Surette ME, Sanchez A, Braquet P, Borgeat P. Priming for the synthesis of 5-lipoxygenase products in human blood ex vivo by human granulocyte-macrophage colony stimulating factor and tumor necrosis factor-α. Lab Invest 1994;70:696-704.
36. Pouliot M, McDonald PP, Khamzina L, Borgeat P, McColl SR. Granulocyte-macrophage colony-stimulating factor enhances 5-lipoxygenase levels in human polymorphonuclear leukocytes. J Immunol 1994;152:851-858.
37. Pouliot M, McDonald PP, Borgeat P, McColl SR. Granulocyte/macrophage colony stimulating factor stimulates the expression of the 5-lipoxygenase-activating protein (FLAP) in human neutrophils. J Exp Med 1994;179:1225-1232.
38. Stankova J, Rola-Pleszczynski M, Dubois CM: Granulocyte-macrophage colony-stimulating factor increases 5-lipoxygenase gene transcription and protein expression in human neutrophils. Blood 1995;85:3719-3726.
39. 4. Eur J Biochem 1991;196:395-400.
40. Meslier N, Aldrich AJ, Bigby TD. Effects of recombinant interferon-γ on the 5-lipoxygenase pathway of rat lung macrophages. Am J Respir Cell Mol Biol 1992;6:93-99.
41. Mangkornkanok MA, Markowitz AS, Esterly JR. Establishment of replicating long-term lines of rabbit macrophages and lymphocytes. J Immunol Methods 1975;7:327-336.
42. Mayernik DG, Ul-Haq A, Rinehart JJ. Differentiation-associated alteration in human monocyte-macrophage accessory cell function. J Immunol 1983;130:2156-2160.
43. Ring WL, Riddick CA, Baker JR, Munafo DA, Bigby TD. Human monocytes lose 5lipoxygenase and FLAP as they mature into monocyte-derived macrophages in vitro. Am J Physiol 1996;271 (Cell Physiol. 40):C372-C2377.
44. Ring WL, Riddick CA, Baker JR, Munafo DA, Bigby TD. Lymphocytes stimulate expression of 5-lipoxygenase and its activating protein in monocytes in vitro via granulocyte macrophage colony-stimulating factor and interleukin-3. J Clin Investig 1996;97:1293-1301.
45. Miyajima A, Kitamura T, Harada N, Yokota T, Arai K. Cytokine receptors and signal transduction. Ann Rev Immunol 1992;10:295-331.
46. Tsuchiya S, Yamabe M, Yamaguchi Y, Kobayashi Y, Konno T, Tada K. Establishment and characterization of a human monocytic leukemia cell line (THP-1). Int J Cancer 1980;26:171.
47. Ring WL, Riddick CA, Baker JR, Glass CK, Bigby TD. Activated lymphocytes increase expression of 5-lipoxygenase and its activating protein in THP-1 cells. Am J Physiol, Cell Physiol 1997;273:C2057-C2064.
48. Riddick CA, Ring WL, Baker JR, Hodulik CR, Bigby TD. Dexamethasone increases expression of 5-lipoxygenase and its activating protein in human monocytes and THP-1 cells. Eur J Biochem 1997;246:112-118.
49. Riddick CA, Ring WL, Baker JR, Bigby TD. Dexamethasone enhances expression of 5lipoxygenase and its activating protein in THP-1 cells conditioned with activated lymphocyte supernatant. Am J Respir Crit Care Med 1995;151:A677.
50. 4 synthase. J Biol Chem 1996;271:22,203-22,210.
51. Bach MK, Brashler JR, Peck RE, Morton DR. Leukotriene C synthatase, a special glutathione S-transferase: Properties of the enzyme and inhibitor studies with special reference to the mode of action of U-60,257, a selective inhibitor of leukotriene synthesis. J Allergy Clin Immunol 1984;74:353-357.
52. 4 synthesized by polymorphonuclear leukocytes. J Biol Chem 1986;261:16,466-16,472.
53. Ibe BO, Campbell WB. Synthesis and metabolism of leukotrienes by human endothelial cells: Influence of prostacyclin release. Biochem Biophys Acta 1988;960:309-321.
54. 4 by human platelets. J Biol Chem 1988;263:174-181.
55. Bigby TD, Meslier N. Transcellular lipoxygenase metabolism between monocytes and platelets. J Immunol 1989;143:1948-1954.
56. 4 monomethyl ester by cytosolic rat glutathione transferases. FEBS Letter 1984;174:289-293.
57. 4. Proc Natl Acad Sci USA 1994;91:7663-7667.
58. 4 synthase. Proc Natl Acad Sci USA 1994;91:9745-9749.
59. 4 synthase activity and attenuates cysteinyl leukotriene production in an eosinophilic substrain of HL-60 cells. J Immunol 1994;153:776-787.
60. 4 synthase in neutrophilic HL-60 cells. Mol Pharmacol 1994;45:1043-1049.
61. 4 synthase activity in human granulocytes. FEBS Letters 1995;377:87-91.
62. 4 synthase. J Biol Chem 1997;272:13,923-13,928.
63. 4 synthase pathway in mouse mast cells. J Biol Chem 1995;270:22,653-22,656.
64. Bigby TD, Hodulik CR, Arden KC, Fu L. Molecular cloning of the human leukotriene Ca. synthase gene and assignment to chromosome 5q35. Mol Med 1996;2:637-646.
65. 4 synthase. Organization, nucleotide sequence, and chromosomal localization to 5q35. J Biol Chem 1996;271:11,356-11,361.
66. 4 synthase in bronchial biopsies from aspirin-intolerant asthmatic patients. Intl Arch Allergy Immunol 1997;113:355-357.
67. van Leenwen BH, Martinson ME, Webb GC, Young IG. Molecular organization of the cytokine gene cluster, involving the human IL-3, IL-4, IL-5, and GM-CSF genes, on human chromosome 5. Blood 1989;73:1142-1148.
68. Marsh DG, Neely JD, Breazeale DR, Ghosh B, Freidhoff LR, Ehrlich-Kautzky E, Schou C, Krihnaswamy G, Beaty TH. Linkage an,alysis of IL-4 and other chromosome 5q31.1 markers and total serum immunoglobulin E concentrations. Science 1994;264:1152-1156.
69. 4 synthase expression in the monocyte-like cell line, THP-1. J Immunol 1999;162:1101-1107.