Cytotoxicity of hemolytic, cytotoxic necrotizing factor 1-positive and - negative Escherichia coli to human T24 bladder cells

Infection and Immunity

Volumn 66, Issue 7, 1998, Pages 3384-3389

  Island, Michael D ^a   Cui, Xiaoling ^a   Foxman, Betsy ^b   Marrs, Carl F ^b   Stamm, Walter E ^c   Stapleton, Ann E ^c   Warren, John W ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

^c UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HEMOLYSIN;

ARTICLE; BACTERIUM ISOLATION; BLADDER; CYSTITIS; CYTOTOXICITY; ESCHERICHIA COLI; HEMOLYSIS; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PYELONEPHRITIS;

EID: 0031816678     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.66.7.3384-3389.1998     Document Type: Article

References (40)

1. Alonso, P., J. Blanco, M. Blanco, and E. A. Gonzalez. 1987. Frequent production of toxins by Escherichia coli strains from urinary tract infections: relation with hemagglutination. FEMS Microbiol. Lett. 48:391-396.
2. Bhakdi, S., H. Bayley, A. Valeva, I. Walev, B. Walker, V. Weller, M. Kehoe, and M. Palmer. 1996. Staphylococcal alpha-toxin, streptolysin-O, and Escherichia coli hemolysin: prototypes of pore-forming bacterial cytolysins. Arch. Microbiol. 165:73-79.
3. Bisicchia, R. C., R. Ciammarughi, A. Caprioli, V. Falbo, and F. Ruggeri. 1985. Toxin production and haemagglutination in strains of Escherichia coli from diarrhoea in Brescia, Italy. J. Hyg. 95:353-361.
4. Blanco, J., M. P. Alonso, E. A. Gonzalez, M. Blanco, and J. I. Garabal. 1990. Virulence factors of bacteraemic Escherichia coli with particular reference to production of cytotoxic necrotizing factor (CNF) by P-fimbriate strains. J. Med. Microbiol. 31:175-183.
5. Blanco, J., M. Blanco, M. P. Alonso, J. E. Blanco, E. A. Gonzalez, and J. I. Garabal. 1992. Characteristics of haemolytic Escherichia coli with particular reference to production of cytotoxic necrotizing factor type 1 (CNF1). Res. Microbiol. 143:869-878.
6. Blum, G., V. Falbo, A. Caprioli, and J. Hacker. 1995. Gene clusters encoding the cytotoxic necrotizing factor type 1, Prs-fimbriae and α-hemolysin form the pathogenicity island II of the uropathogenic Escherichia coli strain J96. FEMS Microbiol. Lett. 126:189-196.
7. Caprioli, A., V. Falbo, L. Roda, F. Ruggeri, and C. Zona. 1983. Partial purification and characterization of an Escherichia coli toxic factor that induces morphological cell alterations. Infect. Immun. 39:1300-1306.
8. Caprioli, A., V. Falbo, F. Ruggeri, L. Baldassarri, R. C. Bisicchia, G. Ippolito, E. Romoli, and G. Donelli. 1987. Cytotoxic necrotizing factor production by hemolytic strains of Escherichia coli causing extraintestinal infections. J. Clin. Microbiol. 25:146-149.
9. Cavalieri, S. J., G. A. Bohach, and I. S. Snyder. 1984. Escherichia coli α-hemolysin: characteristics and probable role in pathogenicity. Microbiol. Rev. 48:326-343.
10. Cavalieri, S. J., and I. S. Snyder. 1982. Effect of Escherichia coli α-hemolysin on human peripheral leukocyte viability in vitro. Infect. Immun. 36:455-461.
11. Cavalieri, S. J., and I. S. Snyder. 1982. Cytotoxic activity of partially purified Escherichia coli α-haemolysin. J. Med. Microbiol. 15:11-21.
12. Cox, C., and F. Hinman, Jr. 1961. Experiments with induced bacteriuria, vesical emptying and bacterial growth on the mechanism of bladder defense to infection. J. Urol. 86:739-748.
13. De Rycke, J. 1990. Toxic effects for lambs of cytotoxic necrotizing factor from Escherichia coli. Res. Vet. Sci. 49:349-354.
14. De Rycke, J., E. A. Gonzalez, J. Blanco, E. Oswald, M. Blanco, and R. Boivin. 1990. Evidence for two types of cytotoxic necrotizing factor in human and animal clinical isolates of Eschenchia coli. J. Clin. Microbiol. 28:694-699.
15. De Rycke, J., P. Mazars, J. P. Nougayrede, C. Tasca, M. Boury, F. Herault, A. Valette, and E. Oswald. 1996. Mitotic block and delayed lethality in HeLa epithelial cells exposed to Escherichia coli BM2-1 producing cytotoxic necrotizing factor type 1. Infect. Immun. 64:1694-1705.
16. De Rycke, J., L. Phan-Thanh, and S. Bernard. 1989. Immunochemical identification and biological characterization of cytotoxic necrotizing factor from Escherichia coli. J. Clin. Microbiol. 27:983-988.
17. Donnenberg, M. S., and R. A. Welch. 1996. Virulence determinants of uropathogenic Escherichia coli, p. 135-174. In H. Mobley and J. Warren (ed.), Urinary tract infections: molecular pathogenesis and clinical management. American Society for Microbiology, Washington, D.C.
18. Falbo, V., M. Famiglietti, and A. Caprioli. 1992. Gene block encoding production of cytotoxic necrotizing factor 1 and hemolysin in Escherichia coli isolates from extraintestinal infections. Infect. Immun. 60:2182-2187.
19. Falbo, V., T. Pace, L. Picci, E. Pizzi, and A. Caprioli. 1993. Isolation and nucleotide sequence of the gene encoding cytotoxic necrotizing factor 1 of Escherichia coli. Infect. Immun. 61:4909-4914.
20. Falzano, L., C. Fiorentini, G. Donelli, E. Michel, C. Kocks, P. Cossart, L. Cabanie, E. Oswald, and P. Boquet. 1993. Induction of phagocytic behaviour in human epithelial cells by Escherichia coli cytotoxic necrotizing factor type 1. Mol. Microbiol. 9:1247-1254.
21. Fiorentini, C., G. Arancia, A. Caprioli, V. Falbo, F. Ruggeri, and G. Donelli. 1988. Cytoskeletal changes induced in Hep-2 cells by the cytotoxic necrotizing factor of Escherichia coli. Toxicon 26:1047-1056.
22. Foxman, B., L. Zhang, K. Palin, P. Tallman, and C. F. Marrs. 1995. Bacterial virulence characteristics of Escherichia coli isolates from first-time urinary tract infection. J. Infect. Dis. 171:1514-1521.
23. Gadeberg, O. V., I. Orskov, and J. M. Rhodes. 1983. Cytotoxic effect of an α-hemolytic Escherichia coli strain on human blood monocytes and granulocytes in vitro. Infect. Immun. 41:358-364.
24. Hagberg, L., I. Engberg, R. Freter, J. Lam, S. Olling, and C. Svanborg Eden. 1983. Ascending, unobstructed urinary tract infection in mice caused by pyelonephritogenic Escherichia coli of human origin. Infect. Immun. 40:273-283.
25. Hostacka, A. 1994. Production of enterotoxin, verotoxin, hemolysin, and cytotoxic necrotizing factor by Escherichia coli of intestinal and extraintestinal origin. Folia Microbiol. 39:79-82.
26. Johnson, D. E., C. V. Lockatell, R. G. Russell, J. R. Hebel, M. D. Island, A. E. Stapleton, W. E. Stamm, and J. W. Warren. 1998. Comparison of Escherichia coli strains recovered from human cystitis or pyelonephritis infections in transurethrally challenged mice. Infect. Immun. 66:3059-3065.
27. Johnson, J. R. 1991. Virulence factors in Escherichia coli urinary tract infection. Clin. Microbiol. Rev. 4:80-128.
28. Mobley, H. L. T., D. Green, A. L. Trifillis, D. E. Johnson, G. R. Chippendale, C. V. Lockatell, B. D. Jones, and J. Warren. 1990. Pyelonephritogenic Escherichia coli and killing of cultured human renal proximal tubular epithelial cells: role of hemolysin in some strains. Infect. Immun. 58:1281-1289.
29. Norden, C. W., G. M. Green, and E. H. Kass. 1968. Antibacterial mechanisms of the urinary bladder. J. Clin. Invest. 47:2689-2700.
30. O'Hanley, P., G. Lalonde, and G. Ji. 1991. Alpha-hemolysin contributes to the pathogenicity of piliated digalactoside-binding Escherichia coli in the kidney: efficiency of an alpha-hemolysin vaccine in preventing renal injury in the BALB/c mouse model of pyelonephritis. Infect. Immun. 59:1153-1161.
31. Oliver, M., N. Harrison, J. Bishop, P. Cole, and G. Laurent. 1989. A rapid and convenient assay for counting cells cultured in microwell plates: application for assessment of growth factors. J. Cell Sci. 92:513-518.
32. Oswald, E., J. De Rycke, P. Lintermans, K. Van Muylem, J. Mainil, G. Daube, and P. Pohl. 1991. Virulence factors associated with cytotoxic necrotizing factor type two in bovine diarrheic and septicemic strains of Escherichia coli. J. Clin. Microbiol. 29:2522-2527.
33. Penfold, R. J., and J. M. Pemberton. 1992. An improved suicide vector for construction of chromosomal insertion mutations in bacteria. Gene 118:145-146.
34. Peres, S. Y., O. Marches, F. Daigle, J. P. Nougayrede, F. Herault, C. Tasca, J. De Rycke, and E. Oswald. 1997. A new cytolethal distending toxin (CDT) from Escherichia coli producing CNF2 blocks HeLa cell division in G2/M phase. Mol. Microbiol. 24:1095-1107.
35. Stamm, W. E., and T. M. Hooton. 1993. Management of urinary tract infections in adults. N. Engl. J. Med. 329:1328-1334.
36. Stamm, W. E., T. M. Hooton, J. R. Johnson, C. Johnson, A. E. Stapleton, P. L. Roberts, S. Moseley, and S. D. Fihn. 1997. Urinary tract infections: from pathogenesis to treatment. J. Infect. Dis. 159:400-406.
37. Stapleton, A., S. Moseley, and W. Stamm. 1991. Urovirulence determinants in Escherichia coli isolates causing first-episode and recurrent cystitis in women. J. Infect. Dis. 163:773-779.
38. Trifillis, A. L., M. S. Donnenberg, X. Cui, R. G. Russell, S. J. Utsalo, H. L. Mobley, and J. W. Warren. 1994. Binding to and killing of human renal epithelial cells by hemolytic P-fimbriated E. coli. Kidney Int. 46:1083-1091.
39. Warren, J. W. 1997. Host-parasite interactions and host defense mechanisms, p. 873-893. In R. W. Schrier and C. W. Gottschalk (ed.), Diseases of the kidney. Little Brown and Company, Boston, Mass.
40. Wilson, A. P. 1996. Cytotoxicity and cell viability assays, p. 263-303. In R. I. Frishney (ed.), Animal cell culture, a practical approach. IRL Press, Oxford, England.