The enterohaemorrhagic Escherichia coli (serotype O157:H7) Tir molecule is not functionally interchangeable for its enteropathogenic E. coli (serotype O127:H6) homologue

Cellular Microbiology

Volumn 3, Issue 8, 2001, Pages 499-510

  Kenny, B ^a  

^a SCHOOL OF MEDICAL SCIENCES   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; ALPHA ACTININ; MEMBRANE RECEPTOR; TYROSINE;

AMINO TERMINAL SEQUENCE; ARTICLE; BACTERIAL MEMBRANE; BACTERIAL VIRULENCE; CONTROLLED STUDY; CYTOSKELETON; DEPHOSPHORYLATION; ESCHERICHIA COLI; ESCHERICHIA COLI O157; HOST CELL; HUMAN; HUMAN CELL; MOLECULE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN LOCALIZATION; PROTEIN MODIFICATION; PROTEIN PHOSPHORYLATION; SEROTYPE;

ACTINS; BACTERIAL PROTEINS; BACTERIAL TYPING TECHNIQUES; BIOLOGICAL TRANSPORT; ESCHERICHIA COLI; ESCHERICHIA COLI O157; ESCHERICHIA COLI PROTEINS; GENE DELETION; HELA CELLS; HUMANS; MUTAGENESIS; O ANTIGENS; RECEPTORS, CELL SURFACE; SEQUENCE HOMOLOGY, AMINO ACID; SEROTYPING;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 0034872761     PISSN: 14625814     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1462-5822.2001.00133.x     Document Type: Article

References (41)

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2. Structural basis for recognition of the translocated intimin receptor (Tir) by intimin from enteropathogenic Escherichia coli
3. Construction and characterization of amplifiable multicopy DNA cloning vehicles derived from the P15A cryptic miniplasmid
4. Identification of the intimin-binding domain of Tir of enteropathogenic Escherichia coli
5. Enterohemorrhagic Escherichia coli O157: H7 produces Tir, which is translocated to the host cell membrane but is not tyrosine phosphorylated
6. Construction of an eae deletion mutant of enteropathogenic Escherichia coli by using a positive-selection suicide vector
7. Interactions between enteropathogenic Escherichia coli and host epithelial cells
8. Initial binding of Shiga toxin-producing Escherichia coli to host cells and subsequent induction of actin rearrangements depend on filamentous EspA-containing surface appendages
9. Identification of CesT, a chaperone for the type III secretion of Tir in enteropathogenic Escherichia coli
10. The cloned locus of enterocyte effacement from enterohemorrhagic Escherichia coli O157: H7 is unable to confer the attaching and effacing phenotype upon E. coli K-12
11. Enteropathogenic E. coli translocated intimin receptor, tir, interacts directly with alpha-actinin
12. Binding of intimin from enteropathogenic Escherichia coli to Tir and to host cells
13. Signal transduction responses following adhesion of verocytotoxin-producing Escherichia coli
14. Phosphorylation of tyrosine 474 of the enteropathogenic Escherichia coli (EPEC) Tir receptor molecule is essential for actin nucleating activity and is preceded by additional host modifications
15. Protein secretion by enteropathogenic Escherichia coli is essential for transducing signals to epithelial cells
16. Intimin-dependent binding of enteropathogenic Escherichia coli to host cells triggers novel signaling events, including tyrosine phosphorylation of phospholipase C gamma
17. Targeting of an enteropathogenic E. coli (EPEC) effector protein to host mitochondria
18. Enteropathogenic Escherichia coli (EPEC) Tir receptor molecule does not undergo full modification when introduced into host cells by EPEC-independent mechanisms
19. Enteropathogenic E. coli (EPEC) protein secretion is induced in response to factors similar to those of the gastrointestinal tract
20. Enteropathogenic E. coli (EPEC) transfers its receptor for intimate adherence into mammalian cells
21. Actin accumulation at sites of bacterial adhesion to tissue culture cells: Basis of a new diagnostic test for enteropathogenic and enterohemorrhagic Escherichia coli
22. A novel EspA-associated surface organelle of enteropathogenic Escherichia coli involved in protein translocation into epithelial cells
23. Cleavage of structural proteins during the assembly of the head of bacteriophage T4
24. The diarrheal response of humans to some classic serotypes of enteropathogenic Escherichia coli is dependent on a plasmid encoding an enteroadhesiveness factor
25. Crystal structure of enteropathogenic Escherichia coli intimin-receptor complex
26. Role of tir and intimin in the virulence of rabbit enteropathogenic Escherichia coli serotype O103: H2
27. A cloned pathogenicity island from enteropathogenic Escherichia coli confers the attaching and effacing phenotype on E. coli K-12
28. A genetic locus of enterocyte effacement conserved among diverse enterobacterial pathogens
29. A novel proline-rich protein, EspF, is secreted from enteropathogenic Escherichia coli via the type III export pathway
30. Translocated EspF protein from enteropathogenic Escherichia coli disrupts host intestinal barrier function
31. Translocated intimin receptors (Tir) of Shiga-toxigenic Escherichia coli isolates belonging to serogroups O26, O111, and O157 react with sera from patients with hemolytic-uremic syndrome and exhibit marked sequence heterogeneity
32. Molecular evolution of a pathogenicity island from enterohemorrhagic Escherichia coli O157: H7
33. Signal transduction between enteropathogenic Escherichia coli (EPEC) and epithelial cells: EPEC induces tyrosine phosphorylation of host cell proteins to initiate cytoskeletal rearrangement and bacterial uptake
34. A pathogenic bacterium triggers epithelial signals to form a functional bacterial receptor that mediates actin pseudopod formation
35. Expression of attaching/effacing activity by enteropathogenic Escherichia coli depends on growth phase, temperature, and protein synthesis upon contact with epithelial cells
36. Versatile low-copy-number plasmid vectors for cloning in Escherichia coli
37. A cluster of fourteen genes from enteropathogenic Escherichia coli is sufficient for the biogenesis of a type IV pilus
38. Use of T7 RNA polymerase to direct expression of cloned genes
39. Expression of the EspB protein of enteropathogenic Escherichia coli within HeLa cells affects stress fibers and cellular morphology
40. Type III secretion-dependent hemolytic activity of enteropathogenic escherichia coli
41. Protein translocation into host epithelial cells by infecting enteropathogenic Escherichia coli