The use of 3-[2-(N,N-diethyl-N-methylammonium)ethyl]-7-methoxy-4-methylcoumarin (AMMC) as a specific CYP2D6 probe in human liver microsomes

Drug Metabolism and Disposition

Volumn 29, Issue 9, 2001, Pages 1196-1200

  Chauret, N ^a   Dobbs, B ^a   Lackman, R L ^a   Bateman, K ^a   Nicoll Griffith, D A ^a   Stresser, D M ^a   Ackermann, J M ^a   Turner, S D ^a   Miller, V P ^a   Crespi, C L ^a  

^a MERCK FROSST CENTRE FOR THERAPEUTIC RESEARCH   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

3 [2 (N,N DIETHYL N METHYLAMMONIUM)ETHYL] 7 METHOXY 4 METHYLCOUMARIN; ANTIBODY; BUFURALOL; COUMARIN DERIVATIVE; CYTOCHROME P450 2D6; FLUORESCENT DYE; METHYLAMMONIUM; O DEMETHYLASE; RECOMBINANT ENZYME; UNCLASSIFIED DRUG;

ARTICLE; CORRELATION FUNCTION; DRUG METABOLISM; ENZYME INHIBITION; FLUORESCENCE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN TISSUE; LIVER MICROSOME; MASS SPECTROMETRY; PRIORITY JOURNAL; XENOBIOTIC METABOLISM;

COUMARINS; CYTOCHROME P-450 CYP2D6; ENZYME INHIBITORS; FLUORESCENT DYES; HUMANS; MICROSOMES, LIVER; QUATERNARY AMMONIUM COMPOUNDS;

EID: 0034872347     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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