Identification of chromosomal deficiencies that modify Drosophila mastermind mutant phenotypes

Genesis

Volumn 30, Issue 4, 2001, Pages 250-258

  Yedvobnick, Barry ^a   Helms, Whitney ^a   Barrett, Britt ^a  

^a EMORY UNIVERSITY   (United States)

Author keywords

Drosophila; Genetic screen; Mastermind; Notch pathway

Indexed keywords

NOTCH RECEPTOR; PROTEIN MAM; UNCLASSIFIED DRUG;

ARTICLE; CELL COMMUNICATION; CHROMOSOME; DROSOPHILA; FORELIMB; HETEROZYGOTE; MUTANT; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; TRANSACTIVATION;

ANIMALS; CHROMOSOME ABERRATIONS; DROSOPHILA; DROSOPHILA PROTEINS; ENHANCER ELEMENTS (GENETICS); GENE EXPRESSION REGULATION; GENES, DOMINANT; GENES, SUPPRESSOR; INSECT PROTEINS; LARVA; MEMBRANE PROTEINS; MICROSCOPY, FLUORESCENCE; MUTATION; NUCLEAR PROTEINS; PHENOTYPE; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION; WING;

EID: 0034867110     PISSN: 1526954X     EISSN: None     Source Type: Journal    
DOI: 10.1002/gene.1071     Document Type: Article

References (26)

1. Distortion of proximodistal information causes JNK-dependent apoptosis Drosophila wing
2. Notch signaling: Cell fate control and signal integration in development
3. The nuclear protein encoded by the Drosophila neurogenic gene mastermind is widely expressed and associates with specific chromosomal sites
4. Feed-back mechanisms affecting notch activation at the dorsoventral boundary in the Drosophila wing
5. The relative expression amounts of apterous and its cofactor dLdb/Chip are critical for dorso-ventral compartmentalization in the Drosophila wing
6. Engineered truncations in the Drosophila Mastermind protein disrupt Notch pathway function
7. Signaling downstream of activated mammalian Notch
8. A screen for genes that function downstream of Ras1 during Drosophila eye development
9. A human protein with sequence similarity to Drosophila Mastermind coordinates the nuclear form of Notch and a CSL protein to build a transcriptional activator complex on target promoters
10. Second-site modifiers of the Delta wing phenotype in Drosophila melanogaster
11. Two different activities of suppressor of hairless during wing development in Drosophila
12. Drosophila Src42A is a negative regulator of RTK signaling
13. Strawberry notch encodes a conserved nuclear protein that functions downstream of notch and regulates gene expression along the developing wing margin of Drosophila
14. Pattern-specific expression of the Drosophila decapentaplegic gene in imaginal disks is regulated by 3′ cis-regulatory elements
15. Genes regulating the remote wing margin enhancer in the Drosophila cut locus
16. Notch signaling: From the outside in
17. A hierarchy of cross-regulation involving Notch, Wingless, Vestigial and Cut organizes the dorsal/ventral axis of the Drosophila wing
18. Homopolymer length variation in the Drosophila gene mastermind
19. Mastermind is a putative activator for Notch
20. Nipped-B, a Drosophila homologue of chromosomal adherins, participates in activation by remote enhancers in the cut and Ultrabithorax genes
21. Notch regulates wingless expression and is not required for reception of the paracrine wingless signal during wing margin neurogenesis in Drosophila
22. The Drosophila neurogenic locus mastermind encodes a nuclear protein unusually rich in amino acid homopolymers
23. The Berkeley Drosophila Genome Project gene disruption project: Single P- inserts mutating 25% of vital Drosophila genes
24. Dorsal wing, a locus that affects dorsoventral wing patterning in Drosophila
25. MAML1, a human homologue of Drosophila Mastermind, is a transcriptional co-activator for NOTCH receptors
26. Apoptotic activities of wild-type and Alzheimer's disease-related mutant presenilins in Drosophila Melanogaster