strawberry notch Encodes a conserved nuclear protein that functions downstream of Notch and regulates gene expression along the developing wing margin of Drosophila

Genes and Development

Volumn 11, Issue 10, 1997, Pages 1341-1353

  Majumdar, Arindam ^a   Nagaraj, Raghavendra ^a   Banerjee, Utpal ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Drosophila development; Notch pathway; sno; wing margin

Indexed keywords

NUCLEAR PROTEIN;

ANIMAL CELL; ARTICLE; BODY GROWTH; EPIDERMIS CELL; GENE EXPRESSION REGULATION; GENE INDUCTION; GENE MUTATION; GENETIC ANALYSIS; GENETIC CONSERVATION; GENETIC REGULATION; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION;

EID: 0030924273     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.11.10.1341     Document Type: Article

References (87)

1. Altschul, S.F., W. Gish, W. Miller, E.W. Myers, and D.J. Lipman. 1990. Basic local alignment search tool. J. Mol. Biol. 215: 403-410.
2. Artavanis-Tsakonas, S. and P. Simpson. 1991. Choosing a cell fate: A view from the Natch locus. Trends Genet. 7: 403-408.
3. Artavanis-Tsakonas, S., K. Matsuno, and M.E. Fortini. 1995. Notch signaling. Science 268: 225-232.
4. Ashburner, M. 1989. Drosophila: A laboratory manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
5. Austin, J. and J.H. Kimble. 1987. glp-1 is required in the germ line for the regulation of the decision between mitosis and meiosis in C. elegans. Cell 51: 589-599.
6. _. 1989. Transcript analysis of glp-1 and lin-12, homologous genes required for cell interactions during development of C. elegans. Cell 58: 565-571.
7. Bailey, A.M. and J.W. Posakony. 1995. Suppressor of Hairless directly activates transcription of Enhancer of split complex genes in response to Notch receptor activity. Genes & Dev. 9: 2609-2622.
8. Bang, A.G. and J.W. Posakony. 1992. The Drosophila gene Hairless encodes a novel basic protein that controls alternative cell fates in adult sensory organ development. Genes & Dev. 6: 1752-1769.
9. Boulianne, G.L., A. de la Concha, J.A. Campos-Ortega, L.Y. Jan, and Y.N. Jan. 1991. The Drosophila neurogenic gene neuralized encodes a novel protein and is expressed in precursors of larval and adult neurons. EMBO J. 10: 2975-2983.
10. Busseau, I., R.J. Diederich, T. Xu, and S. Artavanis-Tsakonas. 1994. A member of the Notch group of interacting loci, dellex, encodes a cytoplasmic basic protein. Genetics 136: 585-596.
11. Brand, A.H. and N. Perrimon. 1993. Targeted gene expression as a means of altering cell fates and generating dominant phe-notypes. Development 118: 401-415.
12. Brown, N. and F.C. Kafatos. 1988. Functional cDNA libraries from Drosophila embryos. J. Mol. Biol. 203: 425-437.
13. Brou, C., F. Logeat, M. Lecourtois, J. Vandekerckhove, P. Kourilsky, F. Schweisguth, and A. Israel. 1994. Inhibition of the DNA-binding activity of Drosophila Suppressor of Hairless and of its human homolog, KBF2/RBP-Jκ, by direct protein-protein interaction with Drosophila Hairless. Genes & Dev. 8: 2491-2503.
14. Cagan, R.L. and D.F. Ready. 1989. Notch is required for successive cell decisions in the developing Drosophila retina. Genes & Dev. 3: 1099-1112.
15. Campos-Ortega, J.A. 1993. Early neurogenesis in Drosophila melanogaster. In The development of Drosophila melanogaster (ed. M. Bate and A. Martinez Arias], pp. 1091-1129. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
16. Cavener, D.R. 1987. Comparison of the consensus sequence flanking translational start sites of Drosophila and vertebrates. Nucleic Acids Res. 15: 1353-1361.
17. Chitnis, A., D. Henrique, J. Lewis, D. Ish-Horowicz, and C. Kintner. 1995. Primary neurogenesis in Xenopus embryos regulated by a homologue of the Drosophila neurogenic gene Delta. Nature 375: 761-766.
18. Christensen, S., V. Kodoyianni, M. Bosenberg, L. Friedman, and J.H. Kimble. 1996. lag-1, a gene required for lin-12 and glp-1 signaling in Caenorhabditis elegans is homologous to human CBF1 and Drosophila Su(H). Development 122: 1373-1383.
19. Cohen, B., M.E. McGuffin, C. Pfeile, D. Segal, and S.M. Cohen. 1992. apterous, a gene required for imaginai disc development in Drosophila encodes a member of the LIM family of developmental regulatory proteins. Genes & Dev. 6: 715-729.
20. Corbin, V., A.M. Michelson, S.M. Abmayr, V. Neel, E. Alcamo, T. Maniatis, and Y.W. Young. 1991. A role for the Drosophila neurogeneic genes in mesoderm differentiation. Cell 67: 311-323.
21. Couso, J.P. and A. Martinez-Arias. 1994. Notch is required for wingless signaling in the epidermis of Drosophila. Cell 79: 259-272.
22. Couso, J.P., S.A. Bishop, and A. Martinez-Arias. 1994. The wingless signaling pathway and the patterning of the wing margin in Drosophila. Development 120: 621-636.
23. Couso, J.P., E. Knust, and A. Martinez-Arias. 1995. Serrate and wingless in Drosophila wing development. Curr. Biol. 5: 1437-1448.
24. Coyle-Thompson, C.A. and U. Banerjee. 1993. The strawberry notch gene functions with Notch in common developmental pathways. Development 119: 377-395.
25. de Celis, J.F., A. Garcia-Bellido, and S.J. Bray. 1996. Activation and function of Notch at the dorsal-ventral boundary of the wing imaginai disc. Development 122: 359-369.
26. Diaz-Benjumea, F.J. and S.M. Cohen. 1995. Serrate signals through Notch to establish a Wingless-dependent organizer at the dorsal/ventral compartment houndary of the Drosophila wing. Development 121: 4215-4225.
27. Diederich R.J., K. Matsuno, H. Hing, and S. Artavanis-Tsakonas. 1994. Cytosolic interaction between Deltex and Notch ankyrin repeats implicates deltex in the Notch signaling pathway. Development 120: 473-481.
28. Doherty, D., G. Feger, S. Younger-Shepherd, L.Y. Jan, and Y.N. Jan. 1996. Delta is a ventral to dorsal signal complementary to Serrate, another Notch ligand, in Drosophila wing formation. Genes & Dev. 10: 421-434.
29. Ellisen, L.W., J. Bird, D.C. West, A.C. Soreng, T.C. Reynolds, and S.D. Smith. 1991. Tan-1, the human homolog of the Drosophila Notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms. Cell 66: 649-661.
30. Fehon, R.G., K. Johansen, I. Rebay, and S. Artavanis-Tsakonas. 1991. Complex cellular and subcellular regulation of Notch expression during embryonic and imaginal development of Drosophila: Implications for Notch function. J. Cell. Biol. 113: 657-669.
31. Fitzgerald, K., H.A. Wilkinson, and I. Greenwald. 1993. glp-1 can substitute for lin-12 in specifying cell fate decisions in Caenorhabditis elegans. Development 119: 1091-1027.
32. Fleming, R.J., T.N. Scottgale, R.J. Diederich, and S. Artavanis-Tsakonas. 1990. The Serrate gene encodes a putative EGF-like transmembrane protein essential for proper ectodermal development of Drosophila melanogaster. Genes & Dev. 4: 2188-2201.
33. Fortini, M.E. and S. Artavanis-Tsakonas. 1994. The Suppressor of Hairless protein participates in Notch receptor signaling. Cell 79: 273-282.
34. Greenwald, I.S., P.W. Sternberg, and H.R. Horvitz. 1983. The lia-12 locus specifies cell fate in Caenorhabditis elegans. Cell 34: 435-444.
35. Hartenstein, V. and J.W. Posakony. 1989. Development of adult sensilla on the wing and the notum of Drosophila melanogaster. Development 107: 389-405.
36. _. 1990. A dual function of the Notch gene in Drosophila sensillum development. Dev. Biol. 142: 13-30.
37. Hartenstein, A.Y., A. Rugendorff, U. Tepass, and V. Hartenstein. 1992. The function of the neurogenic genes during epithelial development in the Drosophila embryo. Development 116: 1203-1220.
38. Heish, J.J. and S.D. Hayward. 1995. Masking the CBF1/RBPJ kappa transcriptional repression domain by Epstein-Barr virus EBNA-2. Science 268: 530-563.
39. Heitzler, P., M. Bourouis, L. Ruel, C. Carteret, and P. Simpson. 1996. Genes of the Enhancer of split and achaete-scute complexes are required for a regulatory loop between Notch and Delta during lateral signaling in Drosophila. Development 122: 161-171.
40. Hing, H.K., X. Sun, and S. Artavanis-Tsakonas. 1994. Modulation of wingless signaling by Notch in Drosophila. Mech. Dev. 47: 261-268.
41. Huang, F., C. Dambly-Chaudiere, and A. Ghysen. 1991. The emergence of sense organs in the wing disc of Drosophila. Development 111: 1087-1095.
42. Irvine, K.D. and E. Wieschaus. 1994. fringe, a boundary-specific signaling molecule, mediates interactions between dorsal and ventral cells during Drosophila wing development. Cell 79: 595-606.
43. Jack, J. and Y. DeLotto. 1992. Effect of wing scalloping mutations on Cut expression and sense organ differentiation in the Drosophila wing margin. Genetics 131: 353-363.
44. Jack, J., D. Dorsett, Y. Delotto, and S. Liu. 1991. Expression of the cut locus in the Drosophila wing margin is required for cell type specification and is regulated by a distant enhancer. Development 113: 735-747.
45. Jan, Y.N. and L.Y. Jan. 1995. Maggot's hair and bug's eye: Role of cell interactions and intrinsic factors in cell fate specification. Neuron 14: 1-5.
46. Jennings, B., A. Preiss, C. Delidakis, and S. Bray. 1994. The Notch signaling pathway is required for Enhancer of split bHLH protein expression during neurogenesis in the Drosophila embryo. Development 120: 3537-3548.
47. Joutel, A., C. Corpechot, A. Ducros, K. Vahedi, H. Chabriat, P. Mouton, S. Alomawitch, V. Domenga, M. Cecillion, E. Marechal, J. Maciazek, C. Vayssiere, C. Cruaud, E.A. Cabanis, M.M. Ruchoux, J. Weissenbach, J.F. Bach, M.G. Bousser, and E.T. Lasserve. 1996. Notch3 mutations in CADASIL, a hereditary adult onset condition causing stroke and dementia. Nature 383: 707-710.
48. Kim, J., K.D. Irvine, and S.B. Carroll. 1995. Cell recognition, signal induction, and symmetrical gene activation at the dorsal-ventral boundary of the developing Drosophila wing. Cell 82: 795-802.
49. Kim, J., A. Sebring, J.J. Esch, M.E. Kraus, K. Vorwerk, J. Magee, and S.B. Carroll. 1996. Integration of positional signals and regulation of wing formation and identity by Drosophila vestigial gene. Nature 382: 133-138.
50. Kopczynski, C.C., A.K. Alton, K. Fechtel, P.J. Kooh, and M.A. Muskavitch. 1988. Delta, a Drosophila neurogenic gene, is transcriptionally complex and encodes a protein related to blood coagulation factors and epidermal growth factor of vertebrates. Genes & Dev. 2: 1723-1735.
51. Kramatschek, B. and J. A. Campos-Ortega. 1994. Neuroectodermal transcription of the Drosophila neurogenic genes E(spl) and HLH-m5 is regulated by proneural genes. Development 120: 815-826.
52. Lecourtois, M. and F. Schweisguth. 1995. The neurogenic Suppressor of Hairless DNA binding protein mediates the transcriptional activation of the Enhancer of Split complex genes triggered by Notch signaling. Genes & Dev. 9: 2598-2608.
53. Lefevre, G. and K. Peterson. 1972. An unusual Notch mimic: Glossy like. Drosophila Inf. Ser. 48: 126-127.
54. Lehmann, R., F. Jimenez, U. Dietrich, and J.A. Campos-Ortega. 1983. On the phenotype and development of mutants of early neurogenesis in Drosophila melanogaster. Wilhelm Roux's Arch. Dev. Biol. 192: 62-74.
55. Lindsell, C.F., C.J. Shawber, J. Boulter, and G. Weinmaster. 1995 Jagged: A mammalian ligand that activates Notch1. Cell 680: 909-917.
56. Matsuno, K., R.J. Diederich, M.J. Go, C.M. Blaumueller, and S. Artavanis-Tsakonas. 1995. Deltex acts as a positive regulator of Notch signaling through interactions with the Notch ankyrin repeats. Development 121: 2633-2644.
57. Menne, T.V. and C. Klambt. 1994. The formation of commissures in the Drosophila CNS depends on the midline cells and on the Notch gene. Development 120: 123-133.
58. Myat, A., D. Henrique, D. Ish-Horowicz, and J. Lewis. 1996. A chick homologue of Serrate and its relationship with Notch and Delta homologues during central neurogenesis. Dev. Biol. 174: 233-247.
59. Nakao, K. and J.A. Campos-Ortega. 1996. Persistent expression of genes of the Enhancer of Split complex supresses neural development in Drosophila. Neuron 16: 275-286.
60. Oellers, N., M. Dehio, and E. Knust. 1994. bHLH proteins encoded by the Enhancer of split complex of Drosophila negatively interfere with transcriptional activation mediated by proneural genes. Mol. Gen. Genet. 244: 465-473.
61. Parr, B.A. and A.P. Mcmohan. 1995 Dorsalizing signal Wnt-7a required for the normal polarity of D-V and A-P axes in the mouse limb. Nature 374: 350 -353.
62. Ptashne, M. and A. Gann. 1993. Activators and targets. Nature 346: 329-331.
63. Phillips, R.G. and J.R. Whittle. 1993. wingless expression mediates determination of peripheral nervous system elements in late stages of Drosophila wing disc development. Development 118: 427-438.
64. Rabinow, L. and J.A. Birchler. 1990. Interactions of vestigial and scabrous with the Notch locus of Drosophila melanogaster. Genetics 125: 41-50.
65. Rhyu, M.S., L.Y. Jan, and Y.N. Jan. 1994. Asymmetric distribution of Numb protein during division of the sensory organ precursor cells confers distinct fates to daughter cells. Cell 76: 477-491.
66. Riddle, R.D., M. Ensini, C. Nelson, T. Tsuchida, T. Jessell, and C. Tabin. 1995. Induction of the LIM homeobox gene Imx1 by Wnt 7a establishes Dorsoventral pattern in the vertebrate limb. Cell 83: 631-640.
67. Rogge, R.D., C.A. Karlovich, and U. Banerjee. 1991. Genetic dissection of a neurodevelopmental pathway: Son of sevenless functions downstrean of sevenless and EGF receptor tyrosine kinases. Cell 64: 39-48.
68. Rubin, G.M. and A. Spradling. 1982. Genetic transformation of Drosophila with transposable element vectors. Science 218: 348-353.
69. Rulifson, E.J. and S.S. Blair. 1995. Notch regulates Wingless expression and is not required for reception of the paracrine Wingless signal during wing margin neurogenesis in Drosophila. Development 121: 2813-2824.
70. Ruohola, H., K.A. Bremer, D. Baker, J.R. Swedlow, L.Y. Jan, and Y.N. Jan. 1991. Role of neurogenic genes in establishment of follicle cell fate and oocyte polarity during oogenesis in Drosophila. Cell 66: 433-449.
71. Schweisguth, F. and J.W. Posakony. 1992. Suppressor of Hairless, the Drosophila homolog of the mouse recombination signal-binding protein gene, controls sensory organ cell fates. Cell 69: 1199-1212.
72. Shawber, C., J. Boulter, J.L. Lindsell, and G. Weinmaster. 1996. Jagged2: A Serrate-like gene expressed during rat embryogenesis. Dev. Biol. 180: 370-376.
73. Singson, A., M.W. Leviten, A.G. Bang, X.H. Hua, and J.W. Posakony. 1994. Direct downstream targets of proneural activators in the imaginal disc include genes involved in lateral inhibitory signaling. Genes & Dev. 8: 2058-2071.
74. Smoller, D., C. Friedel, A. Schmid, D. Bettler, L. Lam, and B. Yedvobnick. 1990. The Drosophila neurogenic locus mastermind encodes a nuclear protein unusually rich in amino acid homopolymers. Genes & Dev. 4: 1688-1700.
75. Spana, E.P., C. Kopczynski, C.S. Goodman, and C.Q. Doe. 1995. Asymmetric localisation of Numb autonomously determines sibling neuron identity in the Drosophila CNS. Development 121: 3489-3494.
76. Spana, E.P. and C.Q. Doe. 1996. Numb antagonizes Notch signaling to specify sibling neuron cell fates. Neuron 17: 21-26.
77. Speicher, S.A., U. Thomas, U. Hinz, and E. Knust. 1994. The Serrate locus of Drosophila and its role in morphogenesis of the wing imaginal discs: Control of cell proliferation. Development 120: 535-544.
78. Spemann, H. 1938. Embryonic development and induction. Yale University Press, New Haven, CT.
79. Tax, F.E., J.J. Yeargers, and J.H. Thomas. 1994. Sequence of C. elegans lag-2 reveals a cell signaling domain shared with delta and serrate of Drosophila. Nature 368: 150-154.
80. Thomas, U., S.A. Speicher, and E. Knust. 1991. The Drosophila gene Serrate encodes a EGF-like transmembrane protein with a complex expression pattern in the embryos and wing discs. Development 111: 749-761.
81. Wehrli, M., A. DiAntonio, I.M. Fearnley, R.J. Smith, and M. Wilcox. 1993. Cloning and characterization of alpha PS1, a novel Drosophila melanogaster integrin. Mech. Dev. 43: 21-36.
82. Wilkinson, H.A., K. Fitzgerald, and I. Greenwald. 1994. Reciprocal changes in expression of the receptor lin-12 and its ligand lag-2 prior to commitment in a C. elegans cell fate decision. Cell 79: 1187-1198.
83. Williams, J.A., J.B. Bell, and S.B. Carroll, 1991. Control of Drosophila wing and haltere development by the nuclear vestigial gene product. Genes & Dev. 5: 2481-2495.
84. Williams, J.A., S.W. Paddock, and S.B. Carroll. 1993. Pattern formation in a secondary field: A hierarchy of regulatory genes subdivides the Drosophila wing disc into discrete subregions. Development 11: 7571-7584.
85. Williams, J.A., S.W. Paddock, K. Vorwerk, and S.B. Carroll. 1994. Organization of wing formation and induction of a wing-patterning gene at the dorsal/ventral compartment boundary. Nature 368: 299-305.
86. Xu, T., L.A. Caron, R.G. Fehon, and S. Artavanis-Tsakonas. 1992. The involvement of the Notch locus in Drosophila oogenesis. Development 115: 913-922.
87. Zipursky, S.L., T.R. Venkatesh, D.B. Teplow, and S. Benzer. 1984. Neuronal development in the Drosophila retina: Monoclonal antibodies as molecular probes. Cell 36: 15 -26.