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Volumn 8, Issue 8, 2001, Pages 767-778

Ingenol esters induce apoptosis in Jurkat cells through an AP-1 and NF-κB independent pathway

Author keywords

Activator protein 1; Apoptosis; Ingenol; Nuclear factor B; Protein kinase C

Indexed keywords

CASP3 PROTEIN, HUMAN; CASPASE; CASPASE 3; DITERPENE; DNA; DNA FRAGMENT; ESTER; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INGENOL; INGENOL DIBENZOATE; LUCIFERASE; PROTEIN KINASE C; TRANSCRIPTION FACTOR AP 1;

EID: 0034864988     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-5521(01)00048-5     Document Type: Article
Times cited : (38)

References (46)
  • 4
    • 0023275783 scopus 로고
    • Structure/activity relationships of polyfunctional diterpenes of the ingenane type. I Tumour promoting activity of homologous, aliphatic 3-esters of ingenol and of delta 7,8-isoingenol-3-tetradecanoate
    • (1987) Carcinogenesis , vol.8 , pp. 1-4
    • Sorg, B.1    Schmidt, R.2    Hecker, E.3
  • 5
    • 0022127593 scopus 로고
    • On the active principles of the spurge family (Euphorbiaceae). XI. [1] The skin irritant and tumour promoting diterpene esters of Euphorbia tirucalli L. originating from South Africa
    • (1985) Z. Naturforsch. [C] Biosci. , vol.40 , pp. 631-646
    • Fürstenberger, G.1    Hecker, E.2
  • 9
    • 0004501722 scopus 로고    scopus 로고
    • Preparation of 13-hydroxyingenols as VCAM-1 formation inhibitors
    • Jpn. Kokai Tokyo Koho JP 07,258,168, 1995
    • (1996) Chem. Abstr. , vol.124 , pp. 87430r
    • Kamimura, D.1    Yamada, K.2
  • 14
    • 0020621035 scopus 로고
    • On the active principles of the Euphorbiaceae VI: Isolation and biological activities of seven milliamines from Euphorbia milii
    • (1983) Planta Med. , vol.47 , pp. 141-147
    • Marston, A.1    Hecker, E.2
  • 19
    • 0029060391 scopus 로고
    • Protein kinase C and lipid signaling for sustained cellular responses
    • (1995) FASEB J. , vol.9 , pp. 484-496
    • Nishizuka, Y.1
  • 39
    • 0029835426 scopus 로고    scopus 로고
    • Structure/activity relationships of polyfunctional diterpenes of the tigliane type. A pharmacophore model for protein-kinase-C activators based on structure/activity studies and molecular modelling of the tumour promoters 12-O-tetradecanoylphorbol 13-acetate and 3-O-tetradecanoylingenol
    • (1996) Eur. J. Biochem. , vol.242 , pp. 417-427
    • Krauter, G.1    Von der Lieth, C.-W.2    Schmidt, R.3    Hecker, E.4
  • 43
    • 0030298294 scopus 로고    scopus 로고
    • Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-κB activation prevents cell death
    • (1996) Cell , vol.87 , pp. 565-576
    • Liu, Z.-G.1    Hsu, H.2    Goeddel, D.V.3    Karin, M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.