Improvement of insulin action in diabetic transgenic mice selectively overexpressing GLUT4 in skeletal muscle

Diabetes

Volumn 45, Issue 1, 1996, Pages 23-27

  Leturque, Armelle ^a   Loizeau, Martine ^a   Vaulont, Sophie ^b   Salminen, Marjo ^b   Girard, Jean ^a  

^a CNRS   (France)

^b INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; GLUCOSE TRANSPORTER; INSULIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; GLUCOSE BLOOD LEVEL; GLUCOSE HOMEOSTASIS; GLUCOSE TOLERANCE; GLUCOSE TRANSPORT; INSULIN BLOOD LEVEL; INSULIN RESPONSE; INSULIN TOLERANCE TEST; MALE; NONHUMAN; PRIORITY JOURNAL; SKELETAL MUSCLE; STREPTOZOCIN DIABETES; TRANSGENIC MOUSE;

EID: 0030048269     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diab.45.1.23     Document Type: Article

References (29)

1. Ziel F, Venkatasen N, Davidson MB: Glucose transport is rate-limiting for skeletal muscle glucose metabolism in normal and STZ-induced diabetic rats. Diabetes 37.885-890, 1988
2. Bell GI, Kanyano T, Buse JB, Burant CF, Takeda J, Lin D, Fukumoto H, Soino S: Molecular biology of mammalian glucose transporters. Diabetes Care 13:198-208, 1990
3. Birnbaum MJ: Identification of a novel gene encoding an insulin-responsive glucose transporter protein Cell 57:305-315, 1989
4. Charron MJ, Brosius FC III, Alper SL, Lodish HF: A glucose transport protein expressed predominantly in insulin-responsive tissues. Proc Natl Acad Sci USA 86:2535-2539, 1989
5. Fukumoto H, Kayano T, Buse JB, Edwards Y, Pilch PF, Bell GI, Seino S: Cloning and characterization of the major insulin-responsive glucose transporter expressed in human skeletal muscle and other insulin-responsive tissues. J Biol Chem 264:7776-7779, 1989
6. James DE, Strube M, Mucckler M: Molecular cloning and characterization of an insulin-regulatable glucose transporter Nature 338:83-87, 1989
7. Klip A, Ramlal T, Bilan PJ, Cartee GD, Gulve EA, Ilolloszy JO: Recruitment of GLUT4 glucose transporters by insulin in diabetic rat skeletal muscle Biochem Biophys Res Commun 172:728-736, 1990
8. Hirshman MF, Goodyear LJ, Wardzala L, Horton ED, Horton ES: Identification of an intracellular pool of glucose transporters from basal and insulin stimulated rat skeletal muscle. J Biol Chem 265:987-991, 1990
9. Douen AG, Ramlal T, Rastogi S, Bilan PJ, Cartee GD, Vranic M, Holloszy JO, Klip A: Exercise induces recruitment of the insulin-responsive glucose transporter. J Biol Chem 265 13427-13430, 1990
10. Goodyear LJ, Hirshman MF, Horton ES: Exercise induced translocation of skeletal muscle glucose transporters. Am J Physiol 261:E795-E799, 1991
11. Rodnick KJ, Holloszy JO, Mondon CE, David EJ: Effects of exercise training on insulin-regulatable glucose transporter protein levels in rat skeletal muscle. Diabetes 39.1425-1429, 1990
12. Shepherd PR, Gnudi L, Tozo E, Yang H. Leach F, Kahn BB: Adipose cell hyperplasia and enhanced glucose disposal in transgenic mice overexpressing GLUT4 selectively in adipose tissue. J Biol Chem 268.22243-22246, 1993
13. Olson AL, Liu M-L. Moye Rowley WS, Buse JB, Bell GI, Pessin JE: Hormonal/metabolic regulation of the human GLUT4/muscle-fat facultative glucose transporter gene in transgenic mice. J Biol Chem 268:9839-9846, 1993
14. Ren J-M, Marshall BA, Gulve EA, Gao J, Johnson DW, Holloszy JO, Mueckler M: Evidence from transgenic mice that glucose transport is rate-limiting for glycogen deposition and glycolysis in skeletal muscle. J Biol Chem 268:16113-16115, 1993
15. Liu M-L, Gibbs EM, McCoid SC, Milici AJ, Stukenbrok HA, McPherson RK, Treadway JL, Pessin JE Transgenic mice expressing the human GLUT4/muscle-fat facilitative glucose transporter protein exhibit efficient glycemic control. Proc Natl Acad Sci USA 90:11:346-11350, 1993
16. Ikemoto S, Thompson KS, Itakura II, Lane MD, Ezaki O. Expression of an insulin-responsive glucose transporter (GLUT4) minigene in transgenic mice: effect of exercise and role in glucose homeostasis. Proc Natl Acad Sci USA 92:865-869, 1995
17. Concordet J-P, Salminen M, Demignon J, Moch C, Maire P, Kahn A, Daegelen D: An opportunistic promoter sharing regulatory sequences with either a muscle-specific or a ubiquitous promoter in the human aldolase A gene. Mol Cell Biol 13:9-17, 1993
18. Chomczynski P, Sacchi N: Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156-159, 1987
19. Postic C, Leturque A, Printz RL, Maulard P, Loizeau M, Granner DK, Girard J: Development and regulation of glucose transporter and hexokinase expression in rat Am J Physiol 266.E548-E559, 1994
20. Klip A, Pâquet MR: Glucose transport and glucose transporters in muscle and their metabolic regulation. Diabetes Care 13 228-243, 1990
21. Neufer PD, Carey JO, Dohm GL: Transcriptional regulation of the gene for glucose transporter GLUT4 in skeletal muscle. J Biol Chem 268: 13824-13829, 1993
22. Marshall BA, Mueckler MM: Differential effects of GLUT-1 or GLUT-4 overexpression on insulin responsiveness in transgenic mice. Am J Physiol 267:E738-E744, 1994
23. Deems RO, Evans JL, Deacon RW, Honer CM, Chu DT, Bürki K, Fillers WS, Cohen DK, Young DA: Expression of human GLUT4 in mice results in increased insulin action. Diabetologia 37:1097-1104, 1904
24. Ren J-M, Marshall BA, Mueckler MM, McCaleb M, Amatruda JM, Shulman GI: Overexpression of Glut4 protein in muscle increases basal and insulin stimulated whole body glucose disposal in conscious mice. J Clin Invest 95:429-432, 1995
25. Marshall BA. Ren J-M, Johnson DW, Gibbs EM, Lillquist JS, Soeller WC, Holloszy JO, Mueckler M: Germline manipulation of glucose homeostasis via alteration of glucose transporter levels in skeletal muscle. J Biol Chem 268:18442-18445, 1993
26. Treadway JL, Hargrove DM, Nardone NA, McPherson RK, Russo JK, Milici AJ, Stukenbrock HA, Gibbs EM, Stevenson RW, Pessin JE: Enhanced peripheral glucose utilization in transgenic mice expressing the human GLUT4 gene. J Biol Chem 269:29956-29961, 1994
27. Gulve EA, Ren J-M, Marshall BA, Gao J, Hansen PA, Hollozy JO, Mueckler M: Glucose transport activity in skeletal muscles from transgenic mice overexpressing GLUT1. J Biol Chem 269:18366-18370, 1994
28. Hansen PA, Gulve EA, Marshall BA, Gao J, Pessin JE, Hollozy JO, Mueckler M. Skeletal muscle glucose transporter and metabolism are enhanced in transgenic mice overexpressing the Glut4 glucose transporter. J Biol Chem 270:1679-1684, 1995
29. Gibbs EM, Stock JL, McCoid SC, Stukenbrok HA, Pessin JE, Stevenson RW, Milici AJ, McNeish JD: Glycemic improvement in diabetic db/db mice by overexpression of the human insulin-regulatable glucose transporter (GLUT4). J Clin Invest 95:1512-1518, 1995