far4, far5, and far6 define three genes required for efficient activation of MAPKs Fus3 and Kss1 and accumulation of glycogen

Current Genetics

Volumn 40, Issue 1, 2001, Pages 13-26

  Cherkasova, V ^a   Elion, E A ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

G1 arrest; MAP kinase; Pheromone response; Saccharomyces cerevisiae

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE; CYTOCHROME P450; FUNGAL ENZYME; FUNGAL PROTEIN; GLYCOGEN; MATING HORMONE ALPHA FACTOR; MITOGEN ACTIVATED PROTEIN KINASE; PHEROMONE; REGULATOR PROTEIN;

ALLELE; ARTICLE; CELL CYCLE G1 PHASE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME REGULATION; FUNGAL GENETICS; FUNGUS GROWTH; FUNGUS MUTANT; GENE MUTATION; GENETIC ANALYSIS; GENETIC REGULATION; GLYCOGEN SYNTHESIS; MICROTUBULE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; RECESSIVE GENE; REGULATORY MECHANISM; SACCHAROMYCES CEREVISIAE; STRAIN DIFFERENCE;

CELL CYCLE PROTEINS; ENZYME ACTIVATION; FUNGAL PROTEINS; G1 PHASE; GENES, FUNGAL; GENETIC COMPLEMENTATION TEST; GLYCOGEN; MICROTUBULE PROTEINS; MITOGEN-ACTIVATED PROTEIN KINASES; MUTATION; PEPTIDES; PHENOTYPE; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SIGNAL TRANSDUCTION;

EID: 0034861574     PISSN: 01728083     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002940100217     Document Type: Article

References (65)

1. Repression of yeast Ste12 transcription factor by direct binding of unphosphorylated Kss1 MAPK and its regulation by the Ste7 MEK
2. BIK1, a protein required for microtubule function during mating and mitosis in Saccharomyces cerevisiae, colocalizes with tubulin
3. cAMP-independent control of sporulation, glycogen metabolism and heat shock resistance in S. cerevisiae
4. Identification of a gene necessary for cell cycle arrest by a negative growth factor of yeast: FAR1 is an inhibitor of a G1 cyclin, CLN2
5. Fus3p and Kss1p control G1 arrest in Saccharomyces cerevisiae through a balance of distinct arrest and proliferative functions that operate in parallel with Far1p
6. Starting the cell cycle: What's the point?
7. Regulation of G protein-initiated signal transduction in yeast: Paradigms and principles
8. Human CPR (cell cycle progression restoration) genes impart a Far-phenotype on yeast cells
9. Routing MAP kinase cascades
10. Pheromone response, mating and cell biology
11. FUS3 encodes a cdc2/CDC28-related kinase required for the transition from mitosis into conjugation
12. FUS3 represses CLN1 and CLN2 and in concert with KSS1 promotes signal transduction
13. Functional redundancy in the yeast cell cycle: FUS3 and KSS1 have both overlapping and unique functions
14. FUS3 phosphorylates multiple components of the mating signal transduction cascade: Evidence for STE12 and FAR1
15. Fus2 localizes near the site of cell fusion and is required for both cell fusion and nuclear alignment during zygote formation
16. Relative dependence of different outputs of the S. cerevisiae pheromone response pathway on the MAP kinase Fus3p
17. Inhibition of glycogen synthesis in Saccharomyces cerevisiae by the mating pheromone alpha-factor
18. Identification and characterization of a mutation affecting the division arrest signaling of the pheromone response pathway in Saccharomyces cerevisiae
19. Pheromone-dependent G1 cell cycle arrest requires Far1 phosphorylation, but may not involve inhibition of Cdc28-Cln2 kinase, in vivo
20. New yeast - Escherichia coli shuttle vectors with in vitro mutagenized yeast genes lacking six-base pair restriction sites
21. MAP kinase pathways in the yeast Saccharomyces cerevisiae
22. Evidence the yeast STE3 gene encodes a receptor for the peptide pheromone a factor: Gene sequence and implications for the structure of the presumed receptor
23. Identification and characterization of FAR3, a gene required for pheromone-mediated G1 arrest in Saccharomyces cerevisiae
24. Connections between the Ras-cyclic AMP pathway and G1 cyclin expression in the budding yeast Saccharomyces cerevisiae
25. Cln3-associated kinase activity in Saccharomyces cerevisiae is regulated by the mating factor pathway
26. The MAP kinase Fus3 associates with and phosphorylates the upstream signaling component Ste5
27. The protein kinase homologue Ste20p is required to link the yeast pheromone response G-protein beta gamma subunits to downstream signalling components
28. Cloning of Saccharomyces cerevisiae STE5 as a suppressor of a Ste20 protein kinase mutant: Structural and functional similarity of Ste5 and Far1
29. The MAPKKK Ste11 regulates vegetative growth through a kinase cascade of shared signaling components
30. POG1, a novel yeast gene, promotes recovery from pheromone arrest via the G1 cyclin CLN2
31. The SH3-domain protein Bem1 coordinates mitogen-activated protein kinase cascade activation with cell cycle control
32. MAP kinases with distinct inhibitory functions impart signaling specificity during yeast differentiation
33. The pathway of cell and nuclear fusion during mating in S. cerevisiae
34. A cytokinesis checkpoint requiring the yeast homologue of an APC-binding protein
35. At the heart of the budding yeast cell cycle
36. Rigorous feedback control of cAMP levels in Saccharomyces cerevisiae
37. G(1) cyclins CLN1 and CLN2 repress the mating factor response pathway at start in the yeast cell cycle
38. The mating factor response pathway regulates transcription of TEC1, a gene involved in pseudohyphal differentiation of Saccharomyces cerevisiae
39. Direct inhibition of the yeast cyclin-dependent kinase Cdc28-Cln by Far1
40. FAR1 links the signal transduction pathway to the cell cycle machinery in yeast
41. Ste50p is involved in regulating filamentous growth in the yeast Saccharomyces cerevisiae and associates with Ste11p
42. Signaling and circuitry of multiple MAPK pathways revealed by a matrix of global gene expression profiles
43. Saccharomyces cerevisiae nuclear fusion requires prior activation by alpha factor
44. A Saccharomyces cerevisiae genomic bank based on a centromerecontaining shuttle vector
45. Targeting, disruption, replacement and allele rescue: Integrative DNA transformation in yeast
46. G1 cell cycle arrest in S. cerevisiae
47. BIM1 encodes a microtubule-binding protein in yeast
48. Methods in yeast genetics
49. A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae
50. Pheromone response and signal transduction during the mating process of Saccharomyces cerevisiae
51. Constitutive mutants of the protein kinase STE11 activate the yeast pheromone response pathway in the absence of the G protein
52. G protein mutations that alter the pheromone response in Saccharomyces cerevisiae
53. APC binds to the novel protein EB1
54. The role of Cdc28 and cyclins during mitosis in the budding yeast S cerevisiae
55. Yeast Bim1p promotes the G1-specific dynamics of microtubules
56. Inhibition of G1 cyclin activity by the Ras/cAMP pathway in yeast
57. Two genes required for cell fusion during conjugation: Evidence for a pheromone-induced surface protein
58. Far1 and Fus3 link the mating pheromone signal transduction pathway to three G1-phase Cdc28 kinase complexes
59. Comparison of the Saccharomyces cerevisiae G1 cyclins: Cln3 may be an upstream activator of Cln1, Cln2, and other cyclins
60. FAR1 is required for posttranscriptional regulation of CLN2 gene expression in response to mating pheromone
61. Stationary phase in the yeast Saccharomyces cerevisiae
62. G1-specific cyclins of S. cerevisiae: Cell cycle periodicity, regulation by mating pheromone, and association with the p34CDC28 protein kinase
63. Differential regulation of Fus3 MAP kinase by tyrosine-specific phosphatases Ptp2/Ptp3 and dual-specificity Msg5 in Saccharomyces cerevisiae