Carrier-mediated enhancement of cognate T cell help: The basis for enhanced immunogenicity of meningococcal outer membrane protein polysaccharide conjugate vaccine

European Journal of Immunology

Volumn 31, Issue 8, 2001, Pages 2373-2381

  Pérez Melgosa, Mercedes ^a   Ochs, Hans D ^b   Linsley, Peter S ^c   Laman, Jon D ^d   Van Meurs, Marjan ^d   Flavell, Richard A ^e   Ernst, Robert K ^a   Miller, Samuel I ^a   Wilson, Christopher B ^a,b  

^a UNIVERSITY OF WASHINGTON   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^c Rosetta Inpharmatics   (United States)

^d ERASMUS UNIVERSITY ROTTERDAM   (Netherlands)

^e YALE UNIVERSITY   (United States)

Author keywords

Adjuvant; Carrier; Vaccine

Indexed keywords

ADJUVANT; B7 ANTIGEN; CD40 ANTIGEN; CD86 ANTIGEN; CYTOKINE; DIPHTHERIA TOXOID; DRUG CARRIER; HAEMOPHILUS INFLUENZAE TYPE B VACCINE; LIGAND; LIPOPOLYSACCHARIDE; MENINGOCOCCUS VACCINE; MITOGENIC AGENT; OUTER MEMBRANE PROTEIN; POLYSACCHARIDE VACCINE; PORIN; TETANUS TOXOID;

AGE; ANIMAL CELL; ANTIBODY PRODUCTION; ANTIBODY RESPONSE; ARTICLE; B LYMPHOCYTE; CONTROLLED STUDY; DOSE RESPONSE; HELPER CELL; HUMAN; HUMAN CELL; IMMUNOGENICITY; INFANT; MOUSE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; REPRODUCIBILITY; T LYMPHOCYTE; TH1 CELL;

ADJUVANTS, IMMUNOLOGIC; ADULT; ANIMALS; ANTIGENS, CD; ANTIGENS, CD86; B-LYMPHOCYTES; BACTERIAL OUTER MEMBRANE PROTEINS; CELLS, CULTURED; CYTOKINES; FLOW CYTOMETRY; HAEMOPHILUS VACCINES; HUMANS; IMMUNOHISTOCHEMISTRY; INFANT, NEWBORN; KILLER CELLS, NATURAL; LYMPHOCYTE ACTIVATION; MEMBRANE GLYCOPROTEINS; MENINGOCOCCAL VACCINES; MICE; MICE, INBRED STRAINS; MONOCYTES; NEISSERIA MENINGITIDIS; POLYSACCHARIDES, BACTERIAL; T-LYMPHOCYTES, HELPER-INDUCER; TETANUS TOXOID; UP-REGULATION; VACCINES, CONJUGATE;

EID: 0034859035     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-4141(200108)31:8<2373::AID-IMMU2373>3.0.CO;2-G     Document Type: Article

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