Impaired IgE response in SWAP-70-deficient mice

European Journal of Immunology

Volumn 31, Issue 8, 2001, Pages 2467-2475

  Borggrefe, Tilman ^a,c,d   Keshavarzi, Sassan ^a,c   Gross, Brigitte ^a,b   Wabl, Matthias ^a,d   Jessberger, Rolf ^a,d  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c BASEL INSTITUTE FOR IMMUNOLOGY   (Switzerland)

^d STANFORD UNIVERSITY   (United States)

Author keywords

Autoantibody; CD40; IgE; Irradiation sensitivity; Isotype switching

Indexed keywords

AUTOANTIBODY; CD40 ANTIGEN; IMMUNOGLOBULIN CLASS; IMMUNOGLOBULIN E; NUCLEAR PROTEIN; PROTEIN SWAP 70; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY PRODUCTION; ARTICLE; B LYMPHOCYTE; CONTROLLED STUDY; GAMMA IRRADIATION; GENE SWITCHING; IMMUNE RESPONSE; IMMUNIZATION; IMMUNOGLOBULIN BLOOD LEVEL; LYMPHOCYTE PROLIFERATION; MOUSE; MOUSE STRAIN; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEFICIENCY; RADIOSENSITIVITY; SIGNAL TRANSDUCTION;

ANIMALS; ANTIGENS, CD40; APOPTOSIS; AUTOANTIBODIES; B-LYMPHOCYTES; CELL DIVISION; DNA-BINDING PROTEINS; GAMMA RAYS; GENE TARGETING; GUANINE NUCLEOTIDE EXCHANGE FACTORS; IMMUNOGLOBULIN CLASS SWITCHING; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; LIPOPOLYSACCHARIDES; LYMPHOCYTE ACTIVATION; MICE; MICE, KNOCKOUT; MUTATION; NUCLEAR PROTEINS; RADIATION TOLERANCE; SIGNAL TRANSDUCTION;

EID: 0034857273     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-4141(200108)31:8<2467::AID-IMMU2467>3.0.CO;2-P     Document Type: Article

References (31)

1. Signal transduction from the B cell antigen-receptor
2. CD40-CD154 interactions in B cell signaling
3. The maintenance and the activation signal of the B cell antigen receptor
4. The immunoglobulin class switch: Beyond "accessibility"
5. Molecular processes that regulate class switching
6. Insights into the control of immunoglobulin class switch recombination from analysis of targeted mice
7. The ability of CD40L, but no lipopolysaccharide, to initiate immunoglobulin switching to Immunoglobulin G1 is explained by differential induction of NF-kB/Rel proteins
8. Looping out and deletion mechanism for the imunoglobulin heavy-chain class switch
9. The SCID but not the RAG-2 gene product is required for S μ-S ε heavy chain class switching
10. Ku80 is required for immunoglobulin isotype switching
11. Ku70 is required for late B cell development and immunoglobulin heavy chain class switching
12. The DNA-dependent protein kinase
13. Deficiency in Msh2 affects the efficiency and local sequence specificity of immunoglobulin class-switch recombination: Parallels with somatic hypermutation
14. Reduced isotype switching in splenic B cells from mice deficient in mismatch repair enzymes
15. Copy choice mechanism of immunoglobulin heavy-chain switch recombination
16. The liaison of isotype class switch and mismatch repair: An illegetimate affair
17. Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID) a potential RNA editing enzyme
18. Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the hyper-IgM syndrome (HIGM2)
19. A B cell specific DNA recombination complex
20. Association of SWAP-70 with the B cell antigen receptor complex
21. Cellular, intracellular, and developmental expression patterns of murine SWAP-70
22. Annexin V-affinity assay: A review on an apoptosis detection system based on phosphatidyl-serine exposure
23. Measurement of cell death
24. The scid mutation in mice causes a general defect in DNA repair
25. Long-term proliferating early pre B cell lines and clones with the potential to develop to surface Ig-positive, mitogen reactive B cells in vitro and in vivo
26. B cell development in mice that lack one or both immunoglobulin kappa light chain genes
27. Differences between IL-4R alpha-deficient and IL-4-deficient mice reveal a role for IL-13 in the regulation of Th2 responses
28. CD40 ligand expressed on B cells in the BXSB mouse model of systemic lupus erythematosus
29. Ionizing radiation and autoimmunity. Induction of autoimmune disease in mice by high dose fractionated total lymphoid irradiation and its prevention by inoculating normal T cells
30. Reduction of arteriosclerosis in mice by inhibition of CD40 signaling
31. Delayed repair of DNA damage by ionizing radiation in cells from patients with juvenile syndrome systemic lupus erythematosus and rheumatoid arthritis