-
4
-
-
0029856893
-
Development of treatment for advanced colorectal cancer: Infusional 5-FU and the role of new agents
-
(1996)
Eur J Cancer
, vol.32 A
, Issue.SUPPL. 5
-
-
Schmoll, H.J.1
-
8
-
-
0031019918
-
Randomized trial comparing monthly low-dose leucovorin and fluorouracil bolus with bimonthly high-dose leucovorin and fluorouracil bolus plus continuous infusion for advanced colorectal cancer: A French intergroup study
-
(1997)
J Clin Oncol
, vol.15
, pp. 808-815
-
-
De Gramont, A.1
Bosset, J.-F.2
Milan, C.3
Rougier, P.4
Bouche, O.5
Etienne, P.-L.6
Morvan, F.7
Louvet, C.8
Guillot, T.9
Francois, E.10
Bedenne, L.11
-
9
-
-
0001446649
-
24h) with or without folinic acid (FA) vs. bolus 5-FU/FA (NCCTG/Mayo) in advanced colorectal cancer (CRC): A randomized phase III study of the EORTC GITCCG and the AIO
-
(Abstract 935)
-
(2000)
Proc Am Soc Clin Oncol
, vol.19
-
-
Schmoll, H.J.1
Köhne, C.H.2
Lorenz, M.3
Schffski, P.4
Voigtmann, R.5
Bokemeyer, C.6
Lutz, M.P.7
Kleeberg, U.8
Ridwelski, K.9
Souchon, R.10
El-Sarafi, M.11
Weiss, U.12
Couvreur, M.L.13
Baron, B.14
Wils, J.A.15
-
10
-
-
0344109583
-
Efficacy of intravenous continuous infusion of fluorouracil compared with bolus administration in advanced colorectal cancer
-
Meta-analysis Group in Cancer
-
(1998)
J Clin Oncol
, vol.16
, pp. 301-308
-
-
-
12
-
-
0026632283
-
Controversial issues in 5-fluorouracil infusion use. Dose intensity, treatment duration, and cost comparison
-
(1992)
Cancer
, vol.70
, pp. 998-1002
-
-
Anderson, N.1
Lokich, J.2
-
13
-
-
0029923720
-
Phase III study of bolus versus infusion fluorouracil with or without cisplatin in advanced colorectal cancer
-
(1996)
J Natl Cancer Inst
, vol.88
, pp. 668-674
-
-
Hansen, T.M.1
Ryan, L.2
Anderson, T.3
Krzywda, B.4
Quebbeman, E.5
Benson, A.6
Haller, D.G.7
Tormey, D.C.8
-
16
-
-
0031935179
-
Assessing patients' needs and preferences in the management of advanced colorectal cancer
-
(1998)
Br J Cancer
, vol.77
, Issue.SUPPL. 2
, pp. 5-7
-
-
Redmond, K.1
-
18
-
-
0031307611
-
Patient preferences for chemotherapy schedules used in the treatment of advanced colorectal cancer - A pilot study
-
(1997)
Eur J Cancer Care
, vol.6
, pp. 291-294
-
-
Topham, C.1
Moore, J.2
-
20
-
-
0000078840
-
A randomized crossover trial comparing oral UFT (uracil/tegafur) + leucovorin (LV) and intravenous fluorouracil (FU) + LV for patient preference and pharmacokinetics in advanced colorectal cancer
-
(Abstract 741)
-
(2000)
Proc Am Soc Clin Oncol
, vol.19
-
-
Borner, M.1
Schöffski, P.2
De Wit, R.3
Caponigro, F.4
Comella, G.5
Sulkes, A.6
Peters, G.7
GrŸnwald, V.8
Wanders, J.9
De Boer, R.10
Martin, C.11
Fumoleau, P.12
-
21
-
-
0026489650
-
A study of quality of life in cancer patients receiving palliative chemotherapy
-
(1992)
Soc Sci Med
, vol.35
, pp. 1505-1509
-
-
Payne, S.A.1
-
22
-
-
0031970715
-
Quality of life issues in the treatment of metastatic breast cancer
-
(1998)
Oncology
, vol.12
, Issue.SUPPL. 4
, pp. 27-31
-
-
Carison, R.W.1
-
25
-
-
0031842077
-
New drugs in the treatment of colorectal carcinoma
-
(1998)
Cancer
, vol.83
, pp. 679-689
-
-
Punt, C.1
-
26
-
-
0031900670
-
Phase I clinical and pharmacologic study of eniluracil plus fluorouracil in patients with advanced cancer
-
(1998)
J Clin Oncol
, vol.16
, pp. 1450-1457
-
-
Schilsky, R.L.1
Hohneker, J.2
Ratain, M.J.3
Crawford, J.4
Hochster, H.5
O'Rourke, M.6
Steinfeldt, H.7
Doucette, M.8
Levin, J.9
Hohneker, J.10
-
27
-
-
0033975358
-
Phase I and pharmacologic study of oral fluorouracil on a chronic daily schedule in combination with the dihydropyrimidine dehydrogenase inactivator eniluracil
-
(2000)
J Clin Oncol
, vol.18
, pp. 915-926
-
-
Baker, S.D.1
Diasio, R.B.2
O'Reilly, S.3
Lucas, V.S.4
Khor, S.P.5
Sartorius, S.E.6
Donehower, R.C.7
Grochow, L.B.8
Spector, T.9
Hohneker, J.A.10
Rowinsky, E.K.11
-
30
-
-
18244414936
-
Phase I clinical and pharmacokinetic study of oral S-1 in patients with advanced solid tumors
-
(2000)
J Clin Oncol
, vol.18
, pp. 2772-2779
-
-
Van Groeningen, C.J.1
Peters, G.J.2
Schornagel, J.H.3
Gall, H.4
Noordhuis, P.5
De Vries, M.J.6
Turner, S.L.7
Swart, M.S.8
Pinedo, H.M.9
Hanauske, A.R.10
Giaccone, G.11
-
31
-
-
0031671094
-
Phase I and pharmacologic study of intermittent twice daily oral therapy with capecitabine in patients with advanced and/or metastatic cancer
-
(1998)
J Clin Oncol
, vol.16
, pp. 2977-2985
-
-
Mackean, M.1
Planting, A.2
Twelves, C.3
Schellens, J.4
Allman, D.5
Osterwalder, B.6
Reigner, B.7
Griffin, T.8
Kaye, S.9
Verweij, J.10
-
32
-
-
0031724433
-
A phase I study of capecitabine in combination with oral leucovorin in patients with intractable solid tumors
-
(1998)
Clin Cancer Res
, vol.4
, pp. 2755-2761
-
-
Cassidy, J.1
Dirix, L.2
Bissett, D.3
Reigner, B.4
Griffin, T.5
Allman, D.6
Osterwalder, B.7
Van Oosterom, A.T.8
-
33
-
-
0034034108
-
A multicenter phase II study of a five-day regimen of oral 5-fluorouracil plus eniluracil with or without leucovorin in patients with metastatic colorectal cancer
-
(2000)
Ann Oncol
, vol.11
, pp. 415-420
-
-
Schilsky, R.L.1
Bukowski, R.2
Burris III, H.3
Hochster, H.4
O'Rourke, M.5
Wall, J.G.6
Mani, S.7
Bonny, T.8
Levin, J.9
Hohneker, J.10
-
34
-
-
0033852502
-
Multicenter phase II study to evaluate a 28-day regimen of oral fluorouracil plus eniluracil in the treatment of patients with previously untreated metastatic colorectal cancer
-
(2000)
J Clin Oncol
, vol.18
, pp. 2894-2901
-
-
Mani, S.1
Hochster, H.2
Beck, T.3
Chevlen, E.M.4
O'Rourke, M.A.5
Weaver, C.H.6
Bell, W.N.7
White, R.8
McGuirt, C.9
Levin, J.10
Hohneker, J.11
Schilsky, R.L.12
Lokich, J.13
-
35
-
-
0034126765
-
Low-dose oral fluorouracil with eniluracil as first-line chemotherapy against advanced breast cancer: A phase II study
-
(2000)
J Clin Oncol
, vol.18
, pp. 2378-2384
-
-
Smith, I.E.1
Johnston, S.R.D.2
O'Brien, M.E.R.3
Hickish, T.F.4
De Boer, R.H.5
Norton, A.6
Cirkel, D.T.7
Barton, C.M.8
-
37
-
-
0033050165
-
Multicenter phase II study of capecitabine in paclitaxel-refractory metastatic breast cancer
-
(1999)
J Clin Oncol
, vol.17
, pp. 485-493
-
-
Blum, J.1
Jones, S.2
Buzdar, A.3
LoRusso, P.4
Kuter, I.5
Vogel, C.6
Osterwalder, B.7
Burger, H.8
Brown, C.9
Griffin, T.10
-
41
-
-
0028099423
-
Phase II trial of uracil and tegafur plus oral leucovorin: An effective oral regimen in the treatment of metastatic colorectal carcinoma
-
(1994)
J Clin Oncol
, vol.12
, pp. 2296-2300
-
-
Pazdur, R.1
Lassere, Y.2
Rhodes, V.3
Ajani, J.A.4
Sugarman, S.M.5
Patt, Y.Z.6
Jones D.V., Jr.7
Markowitz, A.B.8
Abbruzzese, J.L.9
Bready, B.10
-
44
-
-
0002500431
-
Capecitabine as first-line treatment for colorectal cancer (CRC): Integrated results of 1207 patients (pts) from 2 randomized, phase III studies
-
On behalf of the Capecitabine CRC Study Group. (Abstract 263)
-
(2000)
Ann Oncol
, vol.11
, Issue.4
, pp. 60
-
-
Hoff, P.M.1
-
45
-
-
0032698405
-
Post-operative chemoendocrine treatment with mitomycin C, tamoxifen, and UFT is effective for patients with premenopausal estrogen receptor-positive stage II breast cancer
-
(1999)
Breast Cancer Res Treat
, vol.56
, pp. 113-124
-
-
Sugimachi, K.1
Maehara, Y.2
Akazawa, K.3
Nomura, Y.4
Eida, K.5
Ogawa, M.6
Konaga, E.7
Tanaka, N.8
Toge, T.9
Dohi, K.10
Noda, S.11
Maeda, M.12
Monden, Y.13
-
49
-
-
0034089123
-
Phase II study of S-1, a novel oral fluoropyrimidine derivative, in patients with metastatic colorectal carcinoma
-
(2000)
Br J Cancer
, vol.83
, pp. 141-145
-
-
Ohtsu, A.1
Baba, H.2
Sakata, Y.3
Mitachi, Y.4
Horikoshi, N.5
Sugimachi, K.6
Taguchi, T.7
-
50
-
-
0032127244
-
Design of a novel oral fluoropyrimidine carbamate, capecitabine, which generates 5-fluorouracil selectively in tumours by enzymes concentrated in human liver and cancer tissues
-
(1998)
Eur J Cancer
, vol.8
, pp. 1274-1281
-
-
Miwa, M.1
Ura, M.2
Nishida, M.3
Sawada, N.4
Ishikawa, I.5
Ishitsuka, H.6
-
52
-
-
0034016415
-
Preferential activation of capecitabine in tumor following oral administration in colorectal cancer patients
-
(2000)
Cancer Chemother Pharmacol
, vol.45
, pp. 291-297
-
-
Schüller, J.1
Cassidy, J.2
Dumont, E.3
Roos, B.4
Durston, S.5
Banken, L.6
Utoh, M.7
Mori, K.8
Weidekamm, E.9
Reigner, B.10
-
53
-
-
0034016343
-
Capecitabine (Xeloda™), an oral fluoropyrimidine carbamate with substantial activity in advanced colorectal cancer: Results of a randomized phase II study
-
(2000)
J Clin Oncol
, vol.18
, pp. 1338-1345
-
-
Van Cutsem, E.1
Findlay, M.2
Osterwalder, B.3
Kocha, W.4
Dalley, D.5
Pazdur, R.6
Cassidy, J.7
Dirix, L.8
Twelves, C.9
Allman, D.10
Burger, H.U.11
Verweij, J.12
-
55
-
-
0035871538
-
Comparison of oral capecitabine versus intravenous fluorouracil plus levcovonin as first-line treatment in 605 patients with metastatic colectoral cancer: Results of a randomized phase III study
-
(2001)
J Clin Oncol
, vol.19
, pp. 2282-2292
-
-
Hoff, P.M.1
Ansar, R.2
Batist, G.3
-
56
-
-
0003267120
-
First-line capecitabine treatment for metastatic breast cancer (MBC): Updated data from a randomised phase II trial
-
87
-
(2000)
Proc ICACT
-
-
Aapro, M.1
-
58
-
-
0003886074
-
Results of a large phase III trial of Xeloda®/Taxotere® combination therapy vs Taxotere® monotherapy in metastatic breast cancer (MBC) patients
-
Poster presented at the San Antonio Breast Cancer Symposium, San Antonio, USA, (Abstract 381)
-
(2000)
-
-
O'Shaughnessy, J.1
Vukelja, S.2
Moiseyenko, V.3
Miles, D.4
Cervantes, G.5
Chan Navarro, C.6
Mauriac, L.7
Van Hazel, G.8
Lui, W.-Y.9
Ayoub, J.-P.10
Rizel, S.11
Osterwalder, B.12
Rutman, O.13
Leonard, R.14
-
59
-
-
0033040540
-
Phase I and pharmacokinetic study of the oral fluoropyrimidine capecitabine in combination with paclitaxel in patients with advanced solid malignancies
-
(1999)
J Clin Oncol
, vol.17
, pp. 1915-1925
-
-
Villalona-Calero, M.A.1
Weiss, G.R.2
Burris, H.A.3
Kraynak, M.4
Rodrigues, G.5
Drengler, R.L.6
Eckhardt, S.G.7
Reigner, B.8
Moczygemba, J.9
Burger, H.U.10
Griffin, T.11
Von Hoff, D.D.12
Rowinsky, E.K.13
-
61
-
-
0034079455
-
A phase I and pharmacokinetic study of the combination of capecitabine and docetaxel in patients with advanced solid tumours
-
(2000)
Br J Cancer
, vol.83
, pp. 22-29
-
-
Pronk, L.C.1
Vasey, P.2
Sparreboom, A.3
Reigner, B.4
Planting, A.S.T.5
Gordon, R.J.6
Osterwalder, B.7
Verweij, J.8
Twelves, C.9
-
62
-
-
0001258517
-
Efficacy and safety profile of capecitabine (Xeloda®) in combination with paclitaxel (P) in patients with locally advanced or metastatic breast cancer: Preliminary results of a phase II study
-
(Abstract 535)
-
(2000)
Breast Cancer Res Treat
, vol.64
, pp. 124
-
-
Pérez-Manga, G.1
Batista, N.2
Constenla, M.3
Guillem, V.4
Carabantes, F.5
Ahlgren, J.6
Castellanos, J.7
Gonzalez-Baron, M.8
Villman, K.9
Söderberg, K.10
Casinello, J.11
Murias, A.12
Regueiro, P.13
Gregorio Marañon, H.14
-
63
-
-
0000220540
-
Safety profile and preliminary efficacy of capecitabine (Xeloda®) in combination with oxaliplatin in patients with advanced or metastatic solid tumours: Results from a phase I study
-
(Abstract 222)
-
(2000)
Ann Oncol
, vol.11
, Issue.4
, pp. 51
-
-
Evans, J.1
Tabernero, J.2
Cassidy, J.3
Sastre, J.4
Eatock, M.5
Baselga, J.6
Bissett, D.7
Requeiro, P.8
Díaz-Rubio, E.9
-
64
-
-
0000348961
-
Phase I study of capecitabine in combination with a weekly schedule of irinotecan as first-line chemotherapy in metastatic colorectal cancer
-
(Abstract 212)
-
(2000)
Ann Oncol
, vol.11
, Issue.4
, pp. 49
-
-
Vanhoefer, U.J.1
Mayer, S.2
Achterrath, W.3
Hense, J.4
Omidi, S.5
Frings, S.6
Harstrick, A.7
Wilke, H.8
Seeber, S.9
-
66
-
-
0001700120
-
Phase II clinical trial with the combination of oxaliplatin-UFT-1, -leucovorin (OXA-UFT-1, LV) for the first line treatment of advanced colorectal cancer (ACC)
-
(Abstract 220)
-
(2000)
Ann Oncol
, vol.11
, Issue.4
, pp. 50
-
-
Dorta, F.J.1
Feliú, J.2
Vicent, J.3
Garcia-Gir, C.4
Constenla, M.5
Fonseca, E.6
Montalar, J.7
Lomas, M.8
Aparicio, L.A.9
González-Barón, M.10
-
67
-
-
0001867492
-
A phase I/II study of oral uracil/tegafur (UFT®) leucovorin and irinotecan in patients with advanced colorectal cancer
-
(Abstract 193)
-
(2000)
Ann Oncol
, vol.11
, Issue.4
, pp. 45
-
-
Hill, M.1
Mackay, M.2
Cunningham, D.3
Glasspool, R.4
Price, T.5
Campbell, S.6
Massey, A.7
Bailey, S.8
Martin, C.9
Twelves, C.10
|