-
1
-
-
0344109583
-
Efficacy of intravenous continuous infusion of fluorouracil compared with bolus administration in advanced colorectal cancer
-
The Meta-analysis Group in Cancer: Efficacy of intravenous continuous infusion of fluorouracil compared with bolus administration in advanced colorectal cancer. J Clin Oncol 16:301-308, 1998
-
(1998)
J Clin Oncol
, vol.16
, pp. 301-308
-
-
-
2
-
-
0032127244
-
Design of a novel oral fluoropyrimidine carbamate, capecitabine, which generates 5-fluorouracil selectively in tumors by enzymes concentrated in human liver and cancer tissues
-
Miwa M, Ura M, Nishida M, et al: Design of a novel oral fluoropyrimidine carbamate, capecitabine, which generates 5-fluorouracil selectively in tumors by enzymes concentrated in human liver and cancer tissues. Eur J Cancer 34:1274-1281, 1998
-
(1998)
Eur J Cancer
, vol.34
, pp. 1274-1281
-
-
Miwa, M.1
Ura, M.2
Nishida, M.3
-
3
-
-
0031858552
-
Antitumor activities of a novel fluoropyrimidine, N4-pentyloxycarbonyl-5-deoxy-5-fluorocytidine (capecitabine)
-
Ishikawa T, Fukase Y, Yamamoto T, et al: Antitumor activities of a novel fluoropyrimidine, N4-pentyloxycarbonyl-5-deoxy-5-fluorocytidine (capecitabine). Biol Pharm Bull 21:713-717, 1998
-
(1998)
Biol Pharm Bull
, vol.21
, pp. 713-717
-
-
Ishikawa, T.1
Fukase, Y.2
Yamamoto, T.3
-
4
-
-
0344541873
-
Tumor selective delivery of 5-Fura by capecitabine, a new oral fluoropyrimidine carbamate, in human cancer xenografts
-
Ishikawa T, Utoh M, Sawada N, et al: Tumor selective delivery of 5-Fura by capecitabine, a new oral fluoropyrimidine carbamate, in human cancer xenografts. Biochem Pharmacol 55:1091-1097, 1998
-
(1998)
Biochem Pharmacol
, vol.55
, pp. 1091-1097
-
-
Ishikawa, T.1
Utoh, M.2
Sawada, N.3
-
5
-
-
0029790295
-
Clinicopathologic and prognostic significance of an angiogenic factor, thymidine phosphorylase, in human colorectal carcinoma
-
Takebayashi Y, Akiyama S, Akiba S, et al: Clinicopathologic and prognostic significance of an angiogenic factor, thymidine phosphorylase, in human colorectal carcinoma. J Natl Cancer Inst 88:1110-1117, 1996
-
(1996)
J Natl Cancer Inst
, vol.88
, pp. 1110-1117
-
-
Takebayashi, Y.1
Akiyama, S.2
Akiba, S.3
-
6
-
-
0032520168
-
Positive correlation between efficacy of capecitabine and doxifluridine and the ratio of thymidine phosphorylase to dihydropyrimidine dehydrogenase activities in tumors in human cancer xenografts
-
Ishikawa T, Sekiguchi F, Fukase Y, et al: Positive correlation between efficacy of capecitabine and doxifluridine and the ratio of thymidine phosphorylase to dihydropyrimidine dehydrogenase activities in tumors in human cancer xenografts. Cancer Res 58:685-690, 1998
-
(1998)
Cancer Res
, vol.58
, pp. 685-690
-
-
Ishikawa, T.1
Sekiguchi, F.2
Fukase, Y.3
-
7
-
-
0000092361
-
Antitumor efficacy of capecitabine against fluorouracil-sensitive and -resistant tumors
-
abstr 795
-
Cao S, Lu K, Ishitsuka H, et al: Antitumor efficacy of capecitabine against fluorouracil-sensitive and -resistant tumors. Proc Am Soc Clin Oncol 16:226a, 1997 (abstr 795)
-
(1997)
Proc Am Soc Clin Oncol
, vol.16
-
-
Cao, S.1
Lu, K.2
Ishitsuka, H.3
-
8
-
-
85038050327
-
Preferential activation of capecitabine in tumor following oral administration in colorectal cancer patients
-
in press
-
Schüller M, Cassidy J, Reigner B, et al: Preferential activation of capecitabine in tumor following oral administration in colorectal cancer patients. Cancer Chemother Pharmacol (in press)
-
Cancer Chemother Pharmacol
-
-
Schüller, M.1
Cassidy, J.2
Reigner, B.3
-
9
-
-
0031859855
-
Preliminary studies of a novel oral fluoropyrimidine carbamate: Capecitabine
-
Budman DR, Meropol NJ, Reigner B, et al: Preliminary studies of a novel oral fluoropyrimidine carbamate: Capecitabine. J Clin Oncol 16:1795-1802, 1998
-
(1998)
J Clin Oncol
, vol.16
, pp. 1795-1802
-
-
Budman, D.R.1
Meropol, N.J.2
Reigner, B.3
-
10
-
-
0031671094
-
A phase I and pharmacological study of intermittent twice-daily oral therapy with capecitabine in patients with advanced and/or metastatic cancer
-
Mackean MJ, Planting AS, Twelves C, et al: A phase I and pharmacological study of intermittent twice-daily oral therapy with capecitabine in patients with advanced and/or metastatic cancer. J Clin Oncol 16:2977-2985, 1998
-
(1998)
J Clin Oncol
, vol.16
, pp. 2977-2985
-
-
Mackean, M.J.1
Planting, A.S.2
Twelves, C.3
-
11
-
-
0021268738
-
Pharmacokinetics of the diastereoisomer of leucovorin after intravenous and oral administration to normal subjects
-
Straw JA, Szapary D, Wynn WT: Pharmacokinetics of the diastereoisomer of leucovorin after intravenous and oral administration to normal subjects. Cancer Res 44:3114-3119, 1993
-
(1993)
Cancer Res
, vol.44
, pp. 3114-3119
-
-
Straw, J.A.1
Szapary, D.2
Wynn, W.T.3
-
12
-
-
0031724433
-
A phase I study of capecitabine in combination with oral leucovorin in patients with intractable solid tumors
-
Cassidy J, Dirix L, Bisset D, et al: A phase I study of capecitabine in combination with oral leucovorin in patients with intractable solid tumors. Clin Cancer Res 4:2755-2761, 1998
-
(1998)
Clin Cancer Res
, vol.4
, pp. 2755-2761
-
-
Cassidy, J.1
Dirix, L.2
Bisset, D.3
-
14
-
-
0000344523
-
A randomized phase II study of Xeloda™ (capecitabine) in patients with advanced colorectal cancer
-
abstr 798
-
Findlay M, Van Cutsem E, Cocha W, et al: A randomized phase II study of Xeloda™ (capecitabine) in patients with advanced colorectal cancer. Proc Am Soc Clin Oncol 16:227a, 1997 (abstr 798)
-
(1997)
Proc Am Soc Clin Oncol
, vol.16
-
-
Findlay, M.1
Van Cutsem, E.2
Cocha, W.3
-
16
-
-
0027379619
-
The chemotherapy of colon cancer can no longer be ignored
-
Cunningham D, Findlay M: The chemotherapy of colon cancer can no longer be ignored. Eur J Cancer 29A:2077-2079, 1995
-
(1995)
Eur J Cancer
, vol.29 A
, pp. 2077-2079
-
-
Cunningham, D.1
Findlay, M.2
-
17
-
-
0028219974
-
Meta-analysis of randomized trials testing the biochemical modulation of fluorouracil methotrexate in metastatic colorectal cancer
-
Advanced Colorectal Cancer Meta-analysis Project: Meta-analysis of randomized trials testing the biochemical modulation of fluorouracil methotrexate in metastatic colorectal cancer. J Clin Oncol 12:960-969, 1994
-
(1994)
J Clin Oncol
, vol.12
, pp. 960-969
-
-
-
18
-
-
0026721532
-
Modulation of fluorouracil by leucovorin in patients with advanced colorectal cancer: Evidence in terms of response rate
-
Advanced Colorectal Cancer Meta-analysis Project: Modulation of fluorouracil by leucovorin in patients with advanced colorectal cancer: Evidence in terms of response rate. J Clin Oncol 10:896-903, 1992
-
(1992)
J Clin Oncol
, vol.10
, pp. 896-903
-
-
-
19
-
-
0031019918
-
Randomized trial comparing monthly low-dose leucovorin and fluorouracil bolus with bimonthly high-dose leucovorin and fluorouracil bolus plus continuous infusion for advanced colorectal cancer: A French intergroup study
-
De Gramont A, Bosset JF, Milan C, et al: Randomized trial comparing monthly low-dose leucovorin and fluorouracil bolus with bimonthly high-dose leucovorin and fluorouracil bolus plus continuous infusion for advanced colorectal cancer: A French intergroup study. J Clin Oncol 15:808-815, 1997
-
(1997)
J Clin Oncol
, vol.15
, pp. 808-815
-
-
De Gramont, A.1
Bosset, J.F.2
Milan, C.3
-
20
-
-
0030966645
-
Colorectal cancer: Is there an alternative to 5-FU?
-
Bleiberg H: Colorectal cancer: Is there an alternative to 5-FU? Eur J Cancer 33:536-541, 1997
-
(1997)
Eur J Cancer
, vol.33
, pp. 536-541
-
-
Bleiberg, H.1
-
21
-
-
0031947624
-
Raltitrexed (Tomudex)
-
Van Cutsem E: Raltitrexed (Tomudex). Exp Op Invest Drugs 7:823-834, 1998
-
(1998)
Exp Op Invest Drugs
, vol.7
, pp. 823-834
-
-
Van Cutsem, E.1
-
22
-
-
0031014627
-
Phase II study of irinotecan in the treatment of advanced colorectal cancer in chemotherapy-naive patients and patients pretreated with fluorouracil-based chemotherapy
-
Rougier P, Bugat R, Douillard J, et al: Phase II study of irinotecan in the treatment of advanced colorectal cancer in chemotherapy-naive patients and patients pretreated with fluorouracil-based chemotherapy. J Clin Oncol 15:251-260, 1997
-
(1997)
J Clin Oncol
, vol.15
, pp. 251-260
-
-
Rougier, P.1
Bugat, R.2
Douillard, J.3
-
23
-
-
0032585197
-
Randomised trial of irinotecan versus fluorouracil by continuous infusion after fluorouracil failure in patients with metastatic colorectal cancer
-
Rougier Ph, Van Cutsem E, Bajetta E, et al: Randomised trial of irinotecan versus fluorouracil by continuous infusion after fluorouracil failure in patients with metastatic colorectal cancer. Lancet 352:1407-1412, 1998
-
(1998)
Lancet
, vol.352
, pp. 1407-1412
-
-
Rougier, Ph.1
Van Cutsem, E.2
Bajetta, E.3
-
24
-
-
0033053920
-
Clinical activity and benefit of irinotecan (CPT-11) in patients with colorectal cancer truly resistant to 5-fluorouracil (5-FU)
-
Van Cutsem E, Cunningham D, Ten Bokkel Huinink WW, et al: Clinical activity and benefit of irinotecan (CPT-11) in patients with colorectal cancer truly resistant to 5-fluorouracil (5-FU). Eur J Cancer 35:54-59, 1999
-
(1999)
Eur J Cancer
, vol.35
, pp. 54-59
-
-
Van Cutsem, E.1
Cunningham, D.2
Ten Bokkel Huinink, W.W.3
-
25
-
-
0031838679
-
Oxaliplatin for the treatment of advanced colorectal cancer: Future directions
-
Ducreux M, Louvet C, Bekradda M, et al: Oxaliplatin for the treatment of advanced colorectal cancer: Future directions. Semin Oncol 25:47-53, 1998
-
(1998)
Semin Oncol
, vol.25
, pp. 47-53
-
-
Ducreux, M.1
Louvet, C.2
Bekradda, M.3
-
26
-
-
0026460966
-
Systemic infusion versus bolus chemotherapy in measurable colorectal cancer
-
Weinerman B, Shah A, Fields A, et al: Systemic infusion versus bolus chemotherapy in measurable colorectal cancer. Am J Clin Oncol 15:518-523, 1992
-
(1992)
Am J Clin Oncol
, vol.15
, pp. 518-523
-
-
Weinerman, B.1
Shah, A.2
Fields, A.3
-
27
-
-
0029012118
-
Phase II study of fluorouracil and its modulation in advanced colorectal cancer: A Southwest Oncology Group study
-
Leichman CG, Fleming TR, Muggia FM, et al: Phase II study of fluorouracil and its modulation in advanced colorectal cancer: A Southwest Oncology Group study. J Clin Oncol 13:1303-1311, 1995
-
(1995)
J Clin Oncol
, vol.13
, pp. 1303-1311
-
-
Leichman, C.G.1
Fleming, T.R.2
Muggia, F.M.3
-
28
-
-
0027472160
-
The syndrome of 5-fluorouracil cardiotoxicity
-
Robben NC, Pippas AW, Moore JO: The syndrome of 5-fluorouracil cardiotoxicity. Cancer 71:493-509, 1993
-
(1993)
Cancer
, vol.71
, pp. 493-509
-
-
Robben, N.C.1
Pippas, A.W.2
Moore, J.O.3
-
29
-
-
0033050165
-
Multicenter phase II study of capecitabine in paclitaxel-refractory metastatic breast cancer
-
Blum JL, Jones SE, Buzdar AU, et al: Multicenter phase II study of capecitabine in paclitaxel-refractory metastatic breast cancer. J Clin Oncol 17:485-493, 1999
-
(1999)
J Clin Oncol
, vol.17
, pp. 485-493
-
-
Blum, J.L.1
Jones, S.E.2
Buzdar, A.U.3
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