Mechanism of β-adrenergic receptor upregulation induced by ACE inhibition in cultured neonatal rat cardiac myocytes: Roles of bradykinin and protein kinase C

Circulation

Volumn 97, Issue 22, 1998, Pages 2268-2273

  Yonemochi, Hidetoshi ^a   Yasunaga, Seikoh ^a   Teshima, Yasusi ^a   Iwao, Tetsu ^a   Akiyoshi, Kumiko ^a   Nakagawa, Mikiko ^a   Saikawa, Tetsunori ^a   Iwao, Morio ^a  

^a OITA UNIVERSITY   (Japan)

Author keywords

Angiotensin; Bradykinin; Myocytes; Receptors, adrenergic, beta

Indexed keywords

4 (3 TERT BUTYLAMINO 2 HYDROXYPROPOXY) 2 BENZIMIDAZOLONE; ANGIOTENSIN; ANGIOTENSIN 1 RECEPTOR ANTAGONIST; ANGIOTENSIN I; BETA ADRENERGIC RECEPTOR; BRADYKININ; BRADYKININ B2 RECEPTOR; CANDESARTAN; CAPTOPRIL; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; FORSKOLIN; ICATIBANT; INDOMETACIN; ISOPRENALINE; PROTEIN KINASE C; STAUROSPORINE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVATION; HEART MUSCLE CELL; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR DENSITY; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION;

EID: 0032499628     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.97.22.2268     Document Type: Article

References (28)

1. The SOLVD Investigators. Effect of enalapril on mortality and development of heart failure in asymptomatic patients with reduced left ventricular ejection fraction. N Engl J Med. 1992;327:685-691.
2. The SOLVD Investigators. Effect of enalapril on survival in patients with reduced left ventricular ejection fraction and congestive heart failure. N Engl J Med. 1991;325:293-302.
3. Captopril Multicenter Research Group. A placebo-controlled trial of captopril in refractory chronic congestive heart failure. J Am Coll Cardiol. 1983;2:755-763.
4. Hartman JC, Wall TM, Hullinger TG, Shebuski RJ. Reduction of myocardial infarct size in rabbits by ramiprilat: reversal by bradykinin antagonist Hoe 140. J Cardiovasc Pharmacol. 1993;21:996-1003.
5. Wall TM, Sheehy R, Hartmann JC. Role of bradykinin in myocardial preconditioning. J Pharmacol Exp Ther. 1994;270:681-689.
6. Linz W, Schölkens BA. A specific B2-bradykinin receptor antagonist Hoe 140 abolishes the antihypertrophic effect of ramipril. Br J Pharmacol. 1992;105:771-772.
7. Yang X, Zhu Q, Fong J, Gu X, Hicks GK Jr, Bishop SP, Wang T. Enalaprilat, an angiotensin-converting enzyme inhibitor, enhances functional preservation during long-term cardiac preservation: possible involvement of bradykinin and PKC. J Mol Cell Cardiol. 1996;28:1445-1452.
8. Gohlke P, Linz W, Schölkens BA, Kuwer I, Bartenbach S, Schnell A. Unger T. Angiotensin-converting enzyme inhibition improves cardiac function: role of bradykinin. Hypertension. 1994;23:411-418.
9. Maisel AS, Phillips C, Michel MC, Ziegler MG, Carter SM. Regulation of cardiac β-adrenergic receptors by captopril: implications for congestive heart failure. Circulation. 1989;80:669-675.
10. Gilbert WN, Sandoval A, Larrabee P, Renlund DG, O'Connell JB, Bristow MR. Lisinopril lowers cardiac adrenergic drive and increases β-receptor density in the failing human heart. Circulation. 1993;88:472-480.
11. Sanbe A, Takeo S. Long-term treatment with angiotensin I-converting enzyme inhibitors attenuates the loss of cardiac β-adrenoceptor responses in rats with chronic heart failure. Circulation. 1995;92:2666-2675.
12. Yonemochi H, Saikawa T, Yasunaga S, Iwao T, Takakura T, Nakagawa M, Sakata T, Ito M. Angiotensin-converting enzyme inhibitor up-regulates cardiac β-receptors in cultured neonatal rat myocytes. Jpn Circ J. 1997;61:170-179.
13. Minshall R, Nakamura F, Becker RP, Rabito SF. Characterization of bradykinin B2 receptors in adult myocardium and neonatal rat cardiomyocytes. Circ Res. 1995;76:773-780.
14. Nolly H, Carbini LA, Scicli G, Carretero OA, Scicli AG. A local kallikrein-kinin system is present in rat hearts. Hypertension. 1994;23:919-923.
15. Wang Y-X, Gavras I, Wierzba T, Lammek B, Gavras H. Inhibition of nitric oxide, bradykinin, and prostaglandins in normal rats. Hypertension. 1992;19(suppl II):II-255-II-261.
16. Ehring T, Baumgart D, Krajcar M, Hümmelgen M, Kompa S, Heusch G. Attenuation of myocardial stunning by the ACE inhibitor ramiprilat through a signal cascade of bradykinin and prostaglandins but not nitric oxide. Circulation. 1994;90:1368-1385.
17. Ljunggren O, Fredholm BB, Nordstedt C, Ljunghall S, Lermer UH. Role of protein kinase C in bradykinin-induced prostaglandin formation in osteoblasts. Eur J Pharmacol. 1993;244:111-117.
18. Yonemochi H, Saikawa T, Takakura T, Ito S, Takaki R. Effects of calcium antagonists on β-receptors of cultured neonatal rat ventricle. Circulation. 1990;81:1401-1408.
19. Limas CJ, Limas C. Rapid recovery of cardiac beta adrenergic receptors after isoproterenol-induced 'down' regulation. Circ Res. 1984;55:524-531.
20. Campbell DJ, Kladis A, Duncan A-M. Effects of converting enzyme inhibitors on angiotensin and bradykinin peptides. Hypertension. 1994; 23:439-449.
21. Böhm M, Castellono M, Agabit-Rosei E, Flesh M, Paul M, Erdmann E. Dose dependent dissociation of ACE inhibitor effects on blood pressure, cardiac hypertrophy, and β-adrenergic signal transduction. Circulation. 1995;92:3006-3013.
22. Desemeci A, Dhallan RS, Cohen NM, Leddere WJ, Roger TB. Phorbol ester increases calcium current and simulates effects of angiotensin II on cultured neonatal rat heart myocytes. Circ Res. 1988;62:347-357.
23. Shubeita HE, Martinson EA, Van Bilsen M, Cien KR, Heller-Brown J. Transcriptional activation of the cardiac myosin light chain 2 and atrial natriuretic factor genes by protein kinase C in neonatal rat ventricular myocytes. Proc Natl Acad Sci U S A. 1992;89:1305-1309.
24. Reupcke C, Paraschos A, Honbo N, Kaliner JS. A phorbol ester augments cAMP content and adenylyl cyclase activity in neonatal rat cardiac myocytes despite reduced β-adrenoceptor density. Cardiovasc Res. 1993; 27:2179-2185.
25. Karliner JS, Simpson PC. β-Adrenoceptor and adenylyl cyclase regulation in cardiac myocytes growth. Basic Res Cardiol. 1988;83:655-663.
26. Johnson JA, Mochly-Rosen D. Inhibition of spontaneous rate of contraction of neonatal cardiac myocytes by protein kinase C isozymes: a putative role for the epsilon isozyme. Circ Res. 1995;76:654-663.
27. Clerk A, Bogoyevitch MA, Andersson MB, Sugden PH. Differential activation of protein kinase C isoforms by endothelin-1 and phenylephrine and subsequent stimulation of p42 and p44 mitogen-activated protein kinases in ventricular myocytes cultured from neonatal rat hearts. J Biol Chem. 1994;269:32848-32857.
28. Rouet-Benzineb P, Mohammadi K, Perennec J, Poyard M, Bouanani NEIH, Crozatier B. Protein kinase C isoform in normal and failing rabbit hearts. Circ Res. 1996;79:153-161.