Life and death in the cytoplasm: Messages from the 3' end

Current Opinion in Genetics and Development

Volumn 7, Issue 2, 1997, Pages 220-232

  Wickens, Marvin ^a   Anderson, Philip ^a   Jackson, Richard J ^b  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; POLYADENYLIC ACID;

ARTICLE; CELL DEATH; CYTOPLASM; DEVELOPMENTAL GENETICS; HUMAN; LIFE; NONHUMAN; PRIORITY JOURNAL; RNA METABOLISM; RNA TRANSLATION; STOP CODON;

EID: 0030949303     PISSN: 0959437X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0959-437X(97)80132-3     Document Type: Article

References (105)

1. Beelman CA, Parker R: Degradation of mRNA in eukaryotes. Cell 1995, 81:179-183.
2. Beelman CA, Stevens A, Caponigro G, Lagrandeur TE, Hatfield L, Fortner DM, Parker R: An essential component of the decapping enzyme required for normal rates of messenger RNA turnover. Nature 1996, 382:642-646.
3. Muhlrad D, Decker CJ, Parker R: Deadenylation of the unstable mRNA encoded by the yeast MFA2 gene leads to decapping followed by 5′ to 3′ digestion of the transcript. Genes Dev 1994, 8:855-866.
4. Hsu CL, Stevens A: Yeast cells lacking a 5′ to 3′ exonuclease contain mRNA species that are poly(A)-deficient and partially lack the 5′ cap structure. Mol Cell Biol 1993, 13:4826-4835.
5. Muhlrad D, Decker CJ, Parker R: Turnover mechanisms of the stable yeast PGK1 messenger RNA. Mol Cell Biol 1995, 15:2145-2156.
6. Caponigro G, Parker R: Multiple functions for poly(A)-binding protein in messenger RNA decapping and deadenylation in yeast Genes Dev 1995, 9:2421-2432.
7. Jacobson A: Poly(A) metabolism and translation: the closed-loop model. In Translational Control. Edited by Hershey J, Mathews M, Sonenberg N. New York: Cold Spring Harbor Press; 1996:451-480.
8. Gallie DR, Tanguay R: Poly(A) binds to initiation factors and increases cap-dependent translation in vitro. J Biol Chem 1994, 269:17166-17173.
9. Tarun S, Sachs AB: Association of the yeast poly(A) tail binding protein with translation initiation factor elF-4G. EMBO J 1996, 15:7168-7177.
10. Kruys V, Wathelet M, Poupart P, Contreras R, Fiers W, Content J, Huez G: The 3′ untranslated region of the human interferon-β mRNA has an inhibitory effect on translation. Proc Natl Acad Sci USA 1987, 84:3030-6034.
11. Kruys VI, Wathelet MC, Huez GA: Identification of a translational inhibitory element (TIE) in the 3′ untranslated region of the human interferon-βmRNA, Gene 1988, 72:191-200.
12. Kruys V, Marinx P, Shaw G, Deschamps J, Huez G: Translational blockade imposed by cytokine-derived UA-rich sequences. Science 1989, 245:852-855.
13. Fox CA, Wickens MP: Pol(A) removal during oocyte maturation: a default reaction selectively prevented by specific sequences in the 3′-UTR of certain maternal mRNAs. Genes Dev 1990, 4:2287-2298.
14. Varnum SM, Wormington WM: Deadenylation of maternal mRNAs during Xenopus oocyte maturation does not require specific cis-sequences: a default mechanism for translational control. Genes Dev 1990, 4:2278-2289.
15. Goyer C, Altmann M, Lee HS, Blanc A, Deshmukh M, Woolford JL, Trachsel H, Sonenberg N: TIF4631 and TIF 4632: two genes encoding the high-molecular weight subunits of the cap-binding protein complex (eukaryotic initiation factor 4F) contain an RNA recognition motif sequence and carry out an essential function. Mol Cell Biol 1993, 13:4860-4874.
16. Hatfield L, Beelman CA, Stevens A, Parker R: Mutations in trans-acting factors affecting messenger RNA decapping in Saccharomyces cerevisiae. Mol Cell Biol 1996, 16:5830-5838.
17. Jacobson A, Peltz S: Interrelationships of the pathways of mRNA decay and translation in eukaryotic cells. Annu Rev Biochem 1996, 65:693-739.
18. Atkin AL, Altamura N, Leeds P, Culbertson MR: The majority of yeast UPF1 co-localizes with polyribosomes in the cytoplasm. Mol Biol Cell 1995, 6:611-625.
19. Weng YM, Czaplinski K, Peltz SW: Identification and characterization of mutations in the UPF1 gene that affect nonsense suppression and the formation of the upf protein complex but not messenger RNA turnover. Mol Cell Biol 1996, 16:5491-5506.
20. Curatula AM, Nadal MS, Schneider RJ: Rapid degradation of AU-rich element (ARE) mRNAs is activated by ribosome transit and blocked by secondary structure at any position 5′ to the ARE. Mol Cell Biol 1995, 15:6331-6340.
21. Chen CYA, Shyu A-B: AU-rich elements: characterization and importance in mRNA degradation. Trends Biochem Sci 1995, 20:465-470.
22. Ross J: Control of messenger RNA turnover in eukaryotes. Trends Genet 1996, 12:171-175.
23. Ruiz-Echevarria MJ, Czaplinski K, Peltz SW: Making sense of nonsense in yeast. Trends Biochem Sci 1996, 21:433-437.
24. Maquat LE: When cells stop making sense - effects of nonsense codons on RNA metabolism in vertebrate cells. RNA 1995, 1:453-465.
25. Muhlrad D, Parker R: Premature translational termination triggers messenger RNA decapping. Nature 1994, 370:578-581.
26. Zhang SA, Ruiz-Echevarria MJ, Quan Y, Peltz SW: Identification and characterization of a sequence motif involved in nonsense-mediated mRNA decay. Mol Cell Biol 1995, 15:2231-2244.
27. He F, Jacobson A: Identification of a novel component of the nonsense-mediated messenger RNA decay pathway by use of an interacting protein screen. Genes Dev 1995, 9:437-454.
28. Cui Y, Hagan KW, Zhang S, Peltz SW: Identification and characterization of genes that are required for the accelerated degradation of messenger-RNAs containing a premature translational termination codon. Genes Dev 1995, 9:423-436.
29. Kimble J, Anderson P: mRNA and translation. In C. elegans II. Edited by Riddle DL, Blumenthal T, Meyer BJ, Priess JR. New York: Cold Spring Harbor Press; 1997:185-208.
30. Perlick HA, Medghalchi SM, Spencer FA, Kendzior RJ Jr, Dietz HC: Mammalian orthologues of a yeast regulator of nonsense transcript stability. Proc Natl Acad Sci USA 1996, 93:10928-10932.
31. Hodgkin J, Papp A, Pulak R, Ambros V, Anderson P: A new kind of informational suppression in the nematode Caenorhabditis elegans. Genetics 1989, 123:301-313.
32. Peltz SW, He F, Welch E, Jacobson A: Nonsense mediated decay in yeast. Prog Nucleic Acids Res Mol Biol 1997, 47:271-298.
33. Pulak R, Anderson P: mRNA surveillance by the Caenorhabditis elegans smg genes. Genes Dev 1993, 7:1885-1897.
34. He F, Peltz SW, Donahue JL, Rosbash M, Jacobson A: Stabilization and ribosome association of unspliced pre-mRNAs in a yeast upf-mutant. Proc Natl Acad Sci USA 1993, 90:7034-7038.
35. Baumann B, Potash MJ, Kohler G: Consequences of frameshift mutations at the immunoglobulin heavy chain locus of the mouse. EMBO J 1985, 4:351-359.
36. Zhang J, Maquat L: Evidence that the decay of nucleus-associated nonsense messenger RNA for human triosephosphate isomerase involves nonsense codon recognition after splicing. RNA 1996, 2:235-243.
37. Carter KMS, Li S, Wilkinson MF: A splicing-dependent regulatory mechanism that detects translation signals. EMBO J 1996, 15:5965-5975.
38. Zhang S, Welch EM, Hagan K, Brown AH, Peltz SW, Jacobson A: Polysome-associated mRNAs are substrates for the nonsense-mediated mRNa decay pathway in Saccharomyces cerevisiae. RNA 1997, in press.
39. Tanguay RL, Gallie DR: Translational efficiency is regulated by the length of the 3′-untranslated region. Mol Cell Biol 1996, 16:146-156.
40. Gallie DR, Lewis NJ, Marzluff WF: The histone 3′-terminal stem-loop is necessary for translation in chinese-hamster ovary cells. Nucleic Acids Res 1996, 24:1954-1962.
41. Tanguay RL, Gallie DR: Isolation and characterization of the 102-kilodalton RNA binding protein that binds to the 5′-translational and 3′-translational enhancers of tobacco mosaic-virus RNA. J Biol Chem 1996, 271:14316-14322.
42. Wang S. Miller WA: A sequence located 4.5 to 5 kilobases from the end of the Barley Yellow Dwarf Virus (PAV) genome strongly sitmulates translation of uncapped RNA. J Biol Chem 1995, 270:13446-13452.
43. Iizuka N, Najita L, Franzusoff A, Sarnow P: Cap-dependent and cap-independent translation by internal initiation of mRNAs in cell extracts from Saccharomyces cerevisiae. Mol Cell Biol 1994, 14:7322-7330.
44. Tarun SZ, Sachs AB: A common function for messenger RNA 5′ and messenger RNA 3′ ends in translation initiation in yeast. Genes Dev 1995, 23:2997-3007.
45. Sachs AB, Davis RW: The poly(A) binding protein is required for poly(A) shortening and 60S ribosomal subunit-dependent translation initiation. Cell 1989, 58:857-867.
46. Munroe D, Jacobson A: mRNA poly(A) tail, a 3′ enhnacer of translational initiation. Mol Cell Biol 1990, 10:3441-3455.
47. Proweller A, Butler S: Efficient translation of poly(A)-deficient messenger RNAs in Saccharomyces cerevisiae. Genes Dev 1984, 8:2629-2840.
48. Masison DC, Blanc A, Ribas JC, Carroll K, Sonenberg N, Wickner RB: Decoying the cap(-) messenger RNA degradation system by a double-stranded RNA virus and poly(A)-messenger RNA surveillance by a yeast antiviral system. Mol Cell Biol 1995, 15:2763-2771.
49. Ohtake Y, Wickner RB: Yeast virus propagation depends critically on free 60S ribosomal-subunit concentration. Mol Cell Biol 1995, 15:2772-2731.
50. Wang Z-F, Whitfield ML, Ingledue TC, Dominski A, Marzluff WF: The protein that binds the 3′ end of histone mRNA: a novel RNA binding protein required for histone pre-mRNA processing. Genes Dev 1996, 10:3028-3040.
51. Martin F, Schaller A, Egilte S, Schumperli D, Muller N: The gene for histone RNA hairpin binding protein is located on human chromosome 4 and encodes a novel type of RNA-binding protein. EMBO J 1997, in press.
52. Curtis D, Lehmann R, Zamore P: Translational regulation and development Cell 1995, 81:171-176.
53. Wickens M, Kimble J, Strickland S: Translational control of developmental decisions. In Translational Control. Edited by Hershey J, Mathews M, Sonenberg N. New York: Cold Spring Harbor Press; 1996:1411-1450.
54. MacDonald P, Smibert CA: Translational regulation of maternal mRNAs. Curr Opin Genet Dev 1996, 6:403-407.
55. Sheets MD, Fox CA, Hunt T, Vandewoude G, Wickens M: The 3′-untranslated regions of c-mos and cyclin messenger RNAs stimulate translation by regulating cytoplasmic polyadenylation. Genes Dev 1994, 8:926-938.
56. Richter JD: Dynamics of poly(A) addition and removal during early development. In Translational Control. Edited by Hershey J, Mathews M, Sonenberg N. New York: Cold Spring Harbor Press; 1996:481-503.
57. Wormington M, Searfoss AM, Hurney CA: Overexpression of poly(A) binding protein prevents maturation-specific deadenylation and translational inactivation in Xenopus oocytes. EMBO J 1996, 15:900-909.
58. Bouvet CP, Omilli F, Arlot-Bonnemains Y, Legagneux V, Roghi C, Bassez T, Osborne HB: The deadenylation conferred by the 3′ untranslated region of a developmentally controlled mRNA in Xenopus embryos is switched to polyadenylation by deletion of a short sequence element Mol Cell Biol 1994, 14:1893-1900.
59. Stebbins Boaz B, Richter JD: Multiple sequence elements and a maternal mRNA product control CDK2 RNA polyadenylation and translation during early Xenopus development. Mol Cell Biol 1994, 14:5870-5880.
60. Sheets MD, Wu M, Wickens M: Polyadenylation of c-mos messenger-RNA as a control point in Xenopus meiotic maturation. Nature 1995, 374:511-516.
61. Salles FJ, Lieberfarb ME, Wreden C, Gergen JP, Strickland S: Coordinate initiation of Drosophila development by regulated polyadenylation of maternal messenger RNAs. Science 1994, 266:1996-1999.
62. Lieberfarb ME, Chu TY, Wreden C, Theurkauf W, Gergen JP, Strickland S: Mutations that perturb poly(A)-dependent maternal messenger RNA activation block the initiation of development Development 1996, 122:570-588.
63. Gavis ER, Lunsford L, Bergsten SE, Lehmann R: A conserved 90-nucleotide element mediates translational repression of nanos RNA. Development 1996, 122:2791-2800.
64. Verrotti AC, Thompson SR, Wreden C, Strickland S, Wickens M: Evolutionary conservation of sequence elements controlling cytoplasmic polyadenylylation. Proc Natl Acad Sci USA 1996, 93:9027-9032.
65. Huarte J, Stutz A. O'Cornell ML, Gubler P, Belin D, Darrow AL, Strickland S, Vassalli J-D: Transient translational silencing by reversible mRNA deadenylation. Cell 1992, 69:1021-1030.
66. Walker J, Dale M, Standart N: Unmasking messenger RNA in clam oocytes - role of phosphorylation of a 3′-UTR masking element-binding protein at fertilization. Dev Biol 1996, 173:292-305.
67. Gebauer F, Xu W, Cooper GM, Richter JD: Translational control by cytoplasmic polyadenylation of c-mos mRNA is necessary for oocyte maturation in the mouse. EMBO J 1994, 13:5712-5720.
68. Kuge H, Richter JD: Cytoplasmic poly(A) addition induces 5′ cap ribose methylation: implications for the control of maternal mRNA. EMBO J 1995, 14:6301-6310.
69. Wickens M: Forward, backward, how much, when: mechanisms of poly(A) addition and removal and their role in early development Semin Dev Biol 1992, 3:399-412.
70. Bouvet P, Wolffe A: A role for transcription and FRGY2 in masking maternal mRNA within Xenopus oocytes. Cell 1994, 77:931-941.
71. Gunkel N, Braddock N, Thorburn AM, Muckenthaler M, Kingsman AJ, Kingsman SM: Promoter control of translation in Xenopus oocytes. Nucleic Acids Res 1995 23:405-412.
72. Ostarek DH, Ostareck-Lederer A, Wilm M, Thiele BJ, Mann M, Hentze MW: mRNA silencing during erythroid differentiation: hnRNP K and hnRNP E1 regulate 15-lipoxygenase translation from the 3′ end. Cell 1997, in press.
73. Hake LE, Richter JD: CPEB is a specificity factor that mediates cytoplasmic polyadenylation during Xenopus oocyte maturation. Cell 1994, 79:617-627.
74. Stebbins-Boaz B, Hake LE, Richter JD: CPEB controls the cytoplasmic polyadenylation of cyclin, cdk2 and c-mos messenger RNAs and is necessary for oocyte maturation in Xenopus. EMBO J 1996, 15:2582-2592.
75. Bilger A, Fox CA, Wahle E, Wickens M: Nuclear polyadenylation factors recognize cytoplasmic polyadenylation elements. Genes Dev 1994, 8:1106-1116.
76. Ballantyne S, Bilger A, Astrom J, Virtanen A, Wickens M: Poly(A) polymerases in the nucleus and cytoplasm of frog oocytes: dynamic changes during oocyte maturation and early development RNA 1995, 1:64-78.
77. Gebauer F, Richter JD: Cloning and characterization of a Xenapus poly(A) polymerase. Mol Cell Biol 1995, 15:1422-1430.
78. Sonenberg N: mRNA translation: influence of the 5′ and 3′ untranslated regions. Curr Opin Genet Dev 1994, 4:310-315.
79. Grünert S, St Johnston D: RNA localization and the development of asymmetry during Drosophila oogenesis. Curr Opin Genet Dev 1996, 6:395-402.
80. Ostareck-Lederer A, Ostareck DH, Standart N, Thiele BJ: Translation of 15-lipoxygenase messenger RNA is inhibited by a protein that binds to a repeated sequence in the 3′ untranslated region. EMBO J 1994, 13:1476-1481.
81. Goodwin E, Okkema P, Evans T, Kimble J: Translational regulation of tra-2 by its 3′ untranslated region controls sexual identity in C. elegans. Cell 1993, 75:329-339.
82. Dubnau J, Struhl G: RNA recognition and translational regulation by a homeodomain protein. Nature 1996, 379:694-699.
83. Rivera-Pomar R, Niessing D, Schmidt-Ott U, Gehring WJ, Jackle H: RNA binding and translational suppression by bicoid. Nature 1996, 379:746-749.
84. Murata Y, Wharton RP: Binding of pumilio to maternal hunchback mRNA is required for posterior patterning in Drosophila embryos. Cell 1595, 80:747-756.
85. Wharton RP, Struhl G: RNA regulatory elements mediate control of Drosophila body pattern by the posterior morphogen nanos. Cell 1991, 67:955-967.
86. Gavis ER, Lehmann R: Localization of nanos RNA control embryonic polarity. Cell 1992, 71:301-313.
87. Gavis ER, Lehmann R: Translational regulation of nanos by RNA localization. Nature 1894, 326:315-318.
88. Smibert CA, Wilson JE, Kerr K, Macdonald PM: smaug protein represses translation of unrealized nanos mRNA in the Drosophila embryo. Genes Dev 1996, 10:2600-2609.
89. Dahanukar A, Wharton RP: The nanos gradient in Drosophila embryos is generated by translational regulation. Genes Dev 1996, 10:2610-2620.
90. Kim-ha J, Kerr K, Macdonald PM: Translational regulation of oskar mRNA by bruno, an ovarian RNA-binding protein, is essential. Cell 1995, 81:403-412.
91. Liang L, Diehl-Jhomes W, Lasko P: Localization of vasa protein to the Drosophila pole plasm is independent of its RNA-binding and helicase activities. Development 1994, 120:1201-1211.
92. Evans T, Crittenden S, Kodoyianni V, Kimble J: Translational control of maternal glp-1 mRNA establishes an asymmetry in the C. elegans embryo. Cell 1994, 77:183-194.
93. Hunter C,P Kenyan C: Spatial and temporal controls target pal-1 blastomere-specification activity to a single blastomere lineage in C, elegans embryos. Cell 1996, 87:217-226.
94. Draper BW, Mello CC, Bowerman B, Hardin J, Priess JR: MEX-3 is a KH domain protein that regulates blastomere identity in early C. elegans embryos. Cell 1996, 87:205-216.
95. Lee R, Feinbaum R, Ambros V: The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 1993, 75:843-854.
96. Wightman B, Ha I, Ruvkjn G: Post-transcriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans, Cell 1993, 75:855-862.
97. Ha I, Wightman B, Ruvkun G: A bulged lin-4/lin-14 RNA duplex is sufficient for Caenorhabditis elegans lin-14 temporal gradient formation. Genes Dev 1995, 10:3041-3050.
98. Wickens M: Deviants - or emissaries. Nature 1993, 367:17-18.
99. Kwon YK, Hecht NB: Binding of a phosphoprotein to the 3′ untranslated region of the mouse protamine 2 mRNA temporally represses its translation. Mol Cell Biol 1993, 13:6547-6557.
100. Braun RE, Peschon JJ, Behringer RR, Brinster RL, Palmiter RD: Protamine 3′ -untranslated sequences regulate temporal translational control and subcellular localization of growth hormone in spermatids of transgenic mice. Genes Dev 1989, 3:793-802.
101. Frolova L, Legoff X, Rasmussen H, Cheperegin S, Drugeon G, Kress M, Arman I, Haenni A, Celis J, Philippe M ety al.: A highly conserved eukaryotic protein family possessing properties of polypeptide-chain release factor. Nature 1994, 372:701-703.
102. Frolova L, Legoff X, Zhouravleva G, Davydova E, Philippe M, Kisselev L: Eukaryotic polypeptide-chain release factor eRF3 is an eRF1-dependent and ribosome-dependent guanosine triphosphatase. RNA 1996, 2:334-341.
103. Stansfield I, Jones K, Kushnirov V, Dagkesamanskaya A, Poznyakovski A, Paushkin S, Nierras C, Cox B, Teravanesyan M, Tuite M: The products of the SUP45 (eRF1) and SUP35 genes interact to mediate translation termination in Saccharomyces cerevisiae. EMBO J 1995, 14:4365-4373.
104. Zhouravleva G, Frolova L, Legoff X, Leguellec R, Ingevechtomov S, Kisselev L, Philippe M: Termination of translation in eukaryotes is governed by 2 interacting polypeptide-chain release factors, eRF1 and eRF3. EMBO J 1995, 14:4065-4072.
105. Hinnebusch AG: Translational control of GCN4: gene-specific regulation by phosphorylation of elF2. In Translational Control. Edited by Hershey J, Mathews M, Sonenberg N. New York: Cold Spring Harbor Press; 1996:199-244.