FOG-2, a novel F-box containing protien, associates with the GLD-1 RNA binding protein and directs male sex determination in the C. elegans hermaphrodite germline

Development

Volumn 127, Issue 24, 2000, Pages 5265-5276

  Clifford, R ^a   Lee, M H ^a   Nayak, S ^a   Ohmachi, M ^a   Giorgini, F ^a   Schedl, T ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Caenorhabditis elegans; F box; FOG 2; Germline sex determination; GLD 1; Tra 2 mRNA; Translational repression

Indexed keywords

CYTOPLASM PROTEIN; GENE PRODUCT; MESSENGER RNA; RNA BINDING PROTEIN; UBIQUITIN PROTEIN LIGASE;

3' UNTRANSLATED REGION; AMINO TERMINAL SEQUENCE; ANIMAL TISSUE; ARTICLE; CAENORHABDITIS ELEGANS; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DEGRADATION; EVOLUTION; FERTILITY; GENE DUPLICATION; GERM LINE; HERMAPHRODITISM; MOLECULAR CLONING; MULTIGENE FAMILY; NEMATODE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; RNA TRANSLATION; SEX DETERMINATION; SPERMATOGENESIS; TRANSLATION REGULATION;

3' UNTRANSLATED REGIONS; ALLELES; AMINO ACID SEQUENCE; ANIMALS; CAENORHABDITIS ELEGANS PROTEINS; DNA-BINDING PROTEINS; DROSOPHILA PROTEINS; EVOLUTION, MOLECULAR; FEMALE; GENES, HELMINTH; HELMINTH PROTEINS; HERMAPHRODITISM; MALE; MOLECULAR SEQUENCE DATA; MULTIGENE FAMILY; PROTEIN BIOSYNTHESIS; RIBONUCLEOPROTEINS; RNA, MESSENGER; RNA-BINDING PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SEX DETERMINATION (GENETICS); TRANSCRIPTION FACTORS; TWO-HYBRID SYSTEM TECHNIQUES;

ANIMALIA; CAENORHABDITIS ELEGANS; NEMATODA;

EID: 0034519641     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (64)

1. Control of the sperm-oocyte switch in Caenorhabditis elegans hermaphrodites by the fem-3 3′untranslated region
2. mRNA and Translation
3. Histone ubiquitination and chromatin remodeling in mouse spermatogenesis
4. SKP1 connects cell cycle regulators to the ubiquitin proteolysis machinery through a novel motif, the F-box
5. Elimination of false positives that arise in using the two-hybrid system
6. Fog-1, a regulatory gene required for specification of spermatogenesis in the germ line of Caenorhabditis elegans
7. Gain-of-function mutations of fem-3, a sex-determination gene in Caenorhabditis elegans
8. The Pfam protein families database
9. The genetics of Caenorhabditis elegans
10. Genome sequence of the nematode C. elegans: A platform for investigating biology
11. SCF and Cullin/Ring H2-based ubiquitin ligases
12. Characterization of Sam68-like mammalian proteins SLM-1 and SLM-2: SLM-1 is a Src substrate during mitosis
13. Activity of the sex-determining gene tra-2 is modulated to allow spermatogenesis in the C. elegans hermaphrodite
14. The retinoblastoma protein associates with the protein phosphatase type 1 catalytic subunit
15. The fog-3 gene and regulation of cell fate in the germ line of Caenorhabditis elegans
16. Sex and death in the Caenorhabditis elegans
17. The two-hybrid system: An assay for protein-protein interactions
18. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
19. Evolution of male tail morphology and development in rhabditid nematodes related to Caenorhabditis elegans
20. Muscle organization in Caenorhabditis elegans: Localization of proteins implicated in thin filament attachment and I-band organization
21. Gld-1, a tumor suppressor gene required for oocyte development in Caenorhabditis elegans
22. Analysis of multiple roles of gld-1 in germline development: Interactions with the sex determination cascade and the glp-1 signaling pathway
23. Repression by the 3′UTR of fem-3, a sex determining gene, relies on a ubiquitous mog-dependent control in Caenorhabditis elegans
24. The KH domain occurs in a diverse set of RNA-binding protein that include the antiterminator NusA and is probably involved in binding to nucleic acid
25. Translational regulation of tra-2 by its 3′untranslated region controls sexual identity in C. elegans
26. Control of translation initiation in animals
27. Regulatory elements required for development of Caenorhabditis elegans hermaphrodites are conserved in the tra-2 homologue of C. remanei, a male/female sister species
28. Sex and the single worm: Sex determination in the nematode C. elegans
29. Molecular control of vertebrate iron metabolism: mRNA-based regulatory circuits operated by iron, nitric oxide, and oxidative stress
30. CLUSTAL V: Improved software for multiple sequence alignment
31. More sex-determination mutants of Caenorhabditis elegans
32. Sex determination in the nematode Caenorhabditis elegans: Analysis of tra-3 suppressors and characterization of the fem genes
33. More is not better: Brood size and population growth in a self-fertilizing nematode
34. Sel-10, a negative regulator of lin-12 activity in Caenorhabditis elegans, encodes a member of the CDC4 family of proteins
35. The STAR protein, GLD-1, is a translation regulator of sexual identity in Caenorhabditis elegans
36. Mutations in gld-1, a female germ cell-specific tumor suppressor gene in Caenorhabditis elegans, affect a conserved domain also found in Src-associated protein Sam68
37. GLD-1, a cytoplasmic protein essential for oocyte differentiation, shows stage- and sex-specific expression during Caenorhabditis elegans germline development
38. Genetic regulation of entry into meiosis in C. elegans
39. Regulating the yeast kinetochore by ubiquitin-dependent degradation and Skp1p-mediated phorphorylation
40. Molecular basis of loss-of-function mutations in the glp-1 gene of Caenorhabditis elegans
41. NANOS-3 and FBF proteins physically interact to control the sperm-oocyte switch in Caenorhabditis elegans
42. Tra-2 encodes a membrane protein and may mediate cell communication in the Caenorhabditis elegans sex determination pathway
43. Germ-line regulation of the Caenorhabditis elegans sex-determing gene tra-2
44. Control of mRNA decay by heat shock-ubiquitin-proteasome pathway
45. Sequence-specific RNA binding by a Nova KH domain: Implications for paraneoplastic disease and the fragile X syndrome
46. Synergistic activation of transcription by UNC-86 and MEC-3 in Caenorhabditis elegans embryo extracts
47. WebPHYLIP: A web interface to PHYLIP
48. Negative regulation of male development in Caenorhabditis elegans by a protein-protein interaction between TRA-2A and FEM-3
49. Three-dimensional structure and stability of the KH domain: Molecular insights into the fragile X syndrome
50. Molecular characterization of the her-1 gene suggests a direct role in cell signaling during Caenorhabditis elegans sex determination
51. Comparative genomics of the eukaryotes
52. Fog-2, a germ-line-specific sex determination gene required for hermaphrodite spermatogenesis in Caenorhabditis elegens
53. The pre-mRNA binding K protein contains a novel evolutionarily conserved motif
54. A function for monoubiquitination in the internalization of a G protein-coupled receptor
55. CLUSTAL W: Improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice
56. Sex-specific transcriptional regulation of the C. elegans sex-determining gene her-1
57. The polarisation of the anterior-posterior and dorsal-ventral axes during Drosophila oogenesis
58. STAR, a gene family involved in signal transduction and activation of RNA
59. A genetic mapping system in Caenorhabditis elegans based on polymorphic sequence-tagged sites
60. A family of mammalian F-box proteins
61. An Arabidopsis protein that interacts with the cytokinin-inducible response regulator, ARR4, implicated in the His-Asp phosphorylay signal transduction
62. A conserved RNA-binding protein that regulates sexual fates in the C. elegans hermaphrodite germ line