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Volumn 9, Issue 11, 2001, Pages 2827-2841

Synthesis and anti-HIV activity of cosalane analogues incorporating two dichlorodisalicylmethane pharmacophore fragments

(9) Casimiro Garcia, Agustin a De Clercq, Erik b Pannecouque, Christophe b Witvrouw, Myriam b Loftus, Tracy L c Turpin, Jim A c Buckheit Jr , Robert W c Fanwick, Phillip E d Cushman, Mark a

a PURDUE UNIVERSITY (United States)

b REGA INSTITUTE FOR MEDICAL RESEARCH (Belgium)

c SOUTHERN RESEARCH INSTITUTE (United States)

d PURDUE UNIVERSITY (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5ALPHA,3BETA,17BETA DI[4',4' (3'',3'' DICARBOXY 5'',5'' DICHLORO 4'',4'' DIHYDROXYDIPHENYL) 3' BUTENYL]ANDROSTANE; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; COSALANE; N (5ALPHA,3BETA CHOLESTANYL) N[6,6 (3',3'' DICARBOXY 5',5'' DICHLORO 4',4'' DIMETHOXYDIPHENYL) 5 HEXENYL] 3,3 (3',3'' DICARBOXY 5',5'' DICHLORO 4',4'' DIMETHOXYDIPHENYL) 2 PROPENAMIDE; UNCLASSIFIED DRUG; 5ALPHA 3BETA,17BETA DI[3',3' (3'',3''' DICARBOXY 5'',5''' DICHLORO 4'',4''' DIHYDROXYDIPHENYL) 2' PROPENYL]ANDROSTANE; 5ALPHA 3BETA,17BETA DI[4',4' (3'',3''' DICARBOXY 5'',5''' DICHLORO 4'',4''' DIHYDROXYDIPHENYL) 3' BUTENYL]ANDROSTANE; 5ALPHA 3BETA,17BETA DI[N 3',3' (3'',3''' DICARBOXY 5'',5''' DICHLORO 4'',4''' DIMETHOXYDIPHENYL) 2' PROPENYLACETAMIDO]ANDROSTANE; 5ALPHA 3BETA,17BETA DI[N 4',4' (3'',3''' DICARBOXY 5'',5''' DICHLORO 4'',4''' DIMETHOXYDIPHENYL) 3' BUTENYLACETAMIDO]ANDROSTANE; AMIDE; AMINO ACID; ANDROSTANE DERIVATIVE; CD4 ANTIGEN; CHOLESTANE DERIVATIVE; DICHLORODISALICYLMETHANE; GLYCOPROTEIN GP 120; METHANE; N (5ALPHA,3BETA CHOLESTANYL) N [6,6 (3',3'' DICARBOXY 5',5'' DICHLORO 4',4'' DIMETHOXYDIPHENYL) 5 HEXENYL] 3,3 (3',3'' DICARBOXY 5',5'' DICHLORO 4',4'' DIMETHOXYPHENYL) 2 PROPENAMIDE; STEROID;

ANTIVIRAL ACTIVITY; ARTICLE; CELL CULTURE; CONTROLLED STUDY; CYTOPATHOGENIC EFFECT; DRUG PURIFICATION; DRUG SYNTHESIS; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 2; IN VITRO STUDY; PHARMACOPHORE; STRUCTURE ACTIVITY RELATION; VIRUS STRAIN; CELL TYPE; CYTOTOXICITY; DRUG POTENCY; DRUG STRUCTURE; REACTION ANALYSIS; STEREOCHEMISTRY; STRAIN DIFFERENCE;

ANTI-HIV AGENTS; ANTIGENS, CD4; AURINTRICARBOXYLIC ACID; CELL SURVIVAL; DRUG DESIGN; HIV ENVELOPE PROTEIN GP120; HIV-1; HIV-2; HUMANS; INHIBITORY CONCENTRATION 50; SALICYLIC ACIDS; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

EID: 0034806573 PISSN: 09680896 EISSN: None Source Type: Journal
DOI: 10.1016/S0968-0896(01)00152-3 Document Type: Article

Times cited : (8)

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