Synthesis of a cosalane analog with an extended polyanionic pharmacophore conferring enhanced potency as an anti-HIV agent

Bioorganic and Medicinal Chemistry Letters

Volumn 8, Issue 7, 1998, Pages 833-836

  Cushman, Mark ^a   Insaf, Shabana ^a   Ruell, Jeffrey A ^a   Schaeffer, Catherine A ^b   Rice, William G ^b  

^a PURDUE UNIVERSITY   (United States)

^b SAIC FREDERICK INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; CD4 ANTIGEN; COSALANE DERIVATIVE; DRUG CARRIER; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; CYTOPATHOGENIC EFFECT; DRUG POTENCY; DRUG SYNTHESIS; HUMAN IMMUNODEFICIENCY VIRUS 1; NONHUMAN;

ANTI-HIV AGENTS; ANTIGENS, CD4; AURINTRICARBOXYLIC ACID; DRUG DESIGN; HIV-1; HUMANS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MOLECULAR STRUCTURE; PROTEIN CONFORMATION; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 0032492726     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(98)00121-8     Document Type: Article

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