Advances in experimental dyslipidemia and atherosclerosis

Laboratory Investigation

Volumn 81, Issue 9, 2001, Pages 1173-1183

  Moghadasian, M H ^a   Frohlich, J J ^a   McManus, B M ^a  

^a ST PAUL S HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

LIPOPROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ATHEROGENESIS; ATHEROSCLEROSIS; CHLAMYDIASIS; DOG; DYSLIPIDEMIA; EXPERIMENTAL ANIMAL; LIPID METABOLISM; LIPOPROTEIN BLOOD LEVEL; MOUSE; NONHUMAN; PIGEON; PRIORITY JOURNAL; RABBIT; SHORT SURVEY; SWINE; TRANSGENIC ANIMAL;

EID: 0034804411     PISSN: 00236837     EISSN: None     Source Type: Journal    
DOI: 10.1038/labinvest.3780331     Document Type: Short Survey

References (96)

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2. Characterization of plasma lipoproteins of grain- and cholesterol-fed White Carneau and Show Racer pigeons
3. A genetic model for control of hypertriglyceridemia and apolipoprotein B levels in Johns Hopkins colony of St. Thomas Hospital rabbits
4. LCAT modulates atherogenic plasma lipoproteins and the extent of atherosclerosis only in the presence of normal LDL receptors in transgenic rabbits
5. Atherosclerosis in Cebus albifrons monkeys: III. Clinical and pathologic studies
6. Comparative primate atherosclerosis: I. Tissue cholesterol concentration and pathologic anatomy
7. Atherosclerosis in apo E knockout mice infected with multiple pathogens
8. Plasma and aortic lipids in experimental canine atherosclerosis
9. Mouse models of C. pneumoniae infection and atherosclerosis
10. Non-human primate models of atherosclerosis
11. Animal lipoproteins: Chemistry, structure, and comparative aspects
12. A study of atherosclerosis regression in Macaca mulatta: IV. Changes in coronary arteries from animals with atherosclerosis induced for 19 months and then regressed for 24 or 48 months at plasma cholesterol concentrations of 300 or 200 mg/dl
13. A study of atherosclerosis regression in Macaca mulatta: V. Changes in abdominal aorta and carotid and coronary arteries for 38 months and then regressed for 24 or 48 months at plasma cholesterol concentrations of 300 or 200 mg/dl
14. Genetic control of plasma cholesterol: Studies on squirrel monkeys
15. Genetic background determines the extent of atherosclerosis in apo E-deficient mice
16. Sequential morphologic studies of regression of advanced atherosclerosis
17. Complete atherosclerosis regression after human apo E gene transfer in apo E-deficient/nude mice
18. Inhibition of atherosclerosis development in cholesterol-fed human apolipoprotein A-I transgenic rabbits
19. Expression of human apolipoprotein A-II in apolipoprotein E-deficient mice induces features of familial combined hyperlipidemia
20. Overexpression of human apolipoprotein B-100 in transgenic rabbits results in increased levels of LDL and decreased levels of HDL
21. Transgenic rabbits expressing human apolipoprotein (a) develop more extensive atherosclerotic lesions in response to a cholesterol-rich diet
22. Overexpression of hepatic lipase in transgenic rabbits leads to a marked reduction of plasma high density lipoproteins and intermediate density lipoproteins
23. Increased expression of apolipoprotein E in transgenic rabbits results in reduced levels of very low density lipoproteins and an accumulation of low density lipoproteins in plasma
24. Increased atherosclerosis in LDL receptor-null mice lacking ACAT1 in macrophages
25. The effect of ileal bypass on sterol balance and plasma cholesterolin the White Carneau pigeons
26. Cholesteryl ester transfer protein corrects dysfunctional high density lipoproteins and reduces aortic atherosclerosis in lecithin cholesterol acyltransferase transgenic mice
27. Inhibition of VCAM-1 expression in the arterial wall is shared by structurally different antioxidants that reduce early atherosclerosis in NZW rabbits
28. Apolipoprotein B mRNA editing in 12 different mammalian species: Hepatic expression is reflected in low concentrations of apo B-containing lipoproteins
29. Development of coronary atherosclerosis in swine with sever hypercholesterolemia: Lack of influence of von Willebrand factor or acute intimal injury
30. Quantitative assessment of aortic atherosclerosis in APOE*3 Leiden transgenic mice and its relationship to serum cholesterol exposure
31. Overexpression of lecithin:cholesterol acyltransferase in transgenic rabbits prevents diet-induced atherosclerosis
32. Development of transgenic Watanabe Heritable Hyperlipidemic rabbits expressing human apolipoprotein A-I
33. Hyperhomocystinemia enhances vascular inflammation and accelerates atherosclerosis in a murine model
34. Studies on the progression and regression of coronary and peripheral atherosclerosis in the cynomolgus monkey: I. Effects of dipyridamole and aspirin
35. LDL hypercholesterolemia is associated with accumulation of oxidized LDL, atherosclerotic plaque growth, and compensatory vessel enlargement in coronary arteries of miniature pigs
36. Retrogression of atherosclerotic lesions on cessation of cholesterol feeding in the chick
37. Hypolipidemic and hyperlipidemic phenotypes in transgenic mice expressing human apolipoprotein E2
38. Apolipoprotein E2 transgenic rabbits: Modulation of type III hyperlipoproteinemic phenotype by estrogen and occurrence of spontaneous atherosclerosis
39. Influence of animal food on the organism of rabbits
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41. Regression of established natural atherosclerotic lesions by intestinal bypass surgery in pigeons: Structure and chemistry
42. Occlusive atherosclerotic disease of the coronary arteries in monkey (Macaca irus) induced by diet
43. Atherosclerosis in a rhesus monkey with genetic hypercholesterolemia and elevated plasma Lp (a)
44. Endothelial damage and thrombocyte adhesion in pigeon atherosclerosis
45. Experimental infection with bovine herpesvirus-4 enhances atherosclerotic process in rabbits
46. Atherosclerosis in APOE*3-Leiden transgenic mice: From proliferative to atheromatous stage
47. Reduction of atherosclerosis in mice by inhibition of CD40 signaling
48. Canine lipoproteins and atherosclerosis: II. Characterization of plasma lipoproteins associated with atherogenic and nonatherogenic hyperlipidemia
49. Severe atherosclerosis in transgenic mice expressing simian cholesteryl ester transfer protein
50. Experimental canine atherosclerosis and its prevention
51. Hepatic lipase deficiency increases plasma cholesterol but reduces susceptibility to atherosclerosis in apolipoprotein E-deficient mice
52. Therapeutic liver repopulation in a mouse model of hypercholesterolemia
53. Lack of regression of atherosclerotic lesions in phytosterol-treated apo E-deficient mice
54. Proatherogenic and antiatherogenic effects of probucol and phytosterols in apo E-deficient mice: Possible mechanisms of action
55. "Tall oil"-derived phytosterol mixture reduces atherosclerosis in apo E-deficient mice
56. Chlamydia pneumoniae-induced atherosclerosis in a rabbit model
57. Cloning and mRNA tissue distribution of rabbit cholesteryl ester transfer protein
58. Upregulation of VCAM-1 and ICAM-1 at atherosclerosis-prone sites on the endothelium in the ApoE-deficient mouse
59. Intermediate density of lipoprotein levels are strong predictors of the extent of aortic atherosclerosis in the St. Thomas's Hospital rabbit strain
60. Modulation of vascular inflammation in vitro and in vivo by peroxisome proliferator-activated receptor-gamma activators
61. Circulating autoantibodies to oxidized cardiolipin correlate with isoprostane F(2α)-VI levels and the extent of atherosclerosis in apo E-deficient mice: Modulation by vitamin E
62. Vitamin E suppresses isoprostane generation in vivo and reduces atherosclerosis in apo E-deficient mice
63. Development of complex atherosclerotic lesions in pigs with inherited hyper-LDL cholesterolemia bearing mutant alleles for apolipoprotein B
64. Aortic atherosclerosis in pigeons and its complications
65. Species variation in the atherogenic profile of monkeys: Relationship between dietary fats, lipoproteins, and platelet aggregation
66. Transgenic mice expressing high levels of human apolipoprotein B develop severe atherosclerotic lesions in response to a high fat diet
67. Pigeon aortic smooth muscle cells lack a functional low density lipoprotein receptor pathway
68. Lipoprotein mutations in pigs are associated with elevated plasma cholesterol and atherosclerosis
69. The domestic pig: A model for experimental atherosclerosis
70. Atherosclerosis: An inflammatory disease
71. Effects of azithromycin on murine arteriosclerosis exacerbated by Chlamydia pneumoniae
72. Apolipoprotein (a) yeast artificial chromosome transgenic rabbits
73. Low density lipoprotein receptor-negative mice expressing human apolipoprotein B-100 develop complex atherosclerotic lesions on a chow diet: No accentuation by apolipoprotein (a)
74. Genetically determined hypercholesterolemia in a rhesus monkey family due to a deficiency of the LDL receptor
75. Cholesterol balance in atherosclerosis-susceptible and atherosclerosis-resistant pigeons
76. Concentration changes of bile acids in sequential segments of pigeon intestine and their relation to bile acid absorption
77. Metabolic changes in the arterial wall associated with atherosclerosis in the pigeon
78. Coronary artery fine structure in rhesus monkeys: The early atherosclerotic lesions and its progression
79. An appraisal of cholesterol feeding in experimental atherogenesis
80. Long-term induction and regression of diet-induced atherosclerotic lesions in rhesus monkeys: I. Morphological and chemical evidence for regression of lesions in the aorta and carotid and peripheral arteries
81. Pathogenesis of diffuse intimal thickening (DIT) in aortas and coronary arteries of 2 1/2-year old miniature pigs
82. Reduction of isoprostanes and regression of advanced atherosclerosis by apolipoprotein E
83. Regression of atherosclerosis induced by liver-directed gene transfer of apolipoprotein A-I in mice
84. Increased atherosclerosis in hyperlipidemic mice deficient in α-tocopherol transfer protein and vitamin E
85. HDL-associated PAF-AH reduces endothelial adhesiveness in apo E-/-mice
86. Low levels of extrahepatic nonmacrophage apo E inhibit atherosclerosis without correcting hypercholesterolemia in apo E-deficient mice
87. Circulating autoantibodies to oxidized LDL correlate with arterial accumulation and depletion of oxidized LDL in LDL receptor-deficient mice
88. Lipoprotein clearance mechanisms in LDL receptor deficient "apo-B-48-only" and "apo-B-100-only" mice
89. Expression of human apolipoprotein A-I/C-III/A-IV gene cluster in mice induces hyperlipidemia but reduces atherogenesis
90. Regression of atherosclerosis in rabbits: I. Treatment with low-fat diet, hyperoxia and hypolipidemic agents
91. The development of pigeon strains with selected atherosclerosis characteristics
92. Rabbit hepatic lipase cDNA sequence: Low activity is associated with low messenger RNA levels
93. Increased angiotensin II type 1 receptor expression in hypercholesterolemic atherosclerosis in rabbits
94. Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein E
95. LDL immunization induces T-cell-dependent antibody formation and protection against atherosclerosis
96. Effects of lovastatin on suppression and regression of atherosclerosis in lipid-fed rabbits